|
.001 |
.341 |
.001 |
.052 |
.028 |
.004 |
.001 |
.005 |
.026 |
.004 |
.01 |
.318 |
-- |
-- |
-- |
.231 |
.13 |
.09 |
.368 |
.303 |
.188 |
.006 |
.014 |
.024 |
.024 |
.099 |
.002 |
.01 |
.004 |
.11 |
.018 |
.056 |
.0 |
.003 |
.002 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.002 |
.012 |
.775 |
.008 |
.053 |
.023 |
.219 |
.038 |
.007 |
.005 |
.032 |
.001 |
.0 |
.013 |
.0 |
.004 |
.007 |
.266 |
-- |
.003 |
.359 |
.003 |
.025 |
.013 |
.006 |
.018 |
-- |
.02 |
.036 |
.861 |
.002 |
.001 |
.117 |
.06 |
.056 |
.145 |
.002 |
.006 |
.007 |
.232 |
.035 |
.021 |
.194 |
.54 |
.07 |
.005 |
.001 |
.084 |
.043 |
.002 |
.005 |
.001 |
.017 |
.079 |
.007 |
.01 |
.108 |
.125 |
.006 |
.059 |
.0 |
.007 |
.0 |
.534 |
1.0 |
.702 |
.0 |
.018 |
.022 |
.022 |
.015 |
.0 |
.034 |
.019 |
-- |
-- |
.069 |
.045 |
.111 |
.0 |
.0 |
.001 |
.001 |
.0 |
.116 |
.108 |
.007 |
.001 |
.012 |
.001 |
.002 |
.028 |
.006 |
.005 |
.001 |
.0 |
.084 |
.121 |
.999 |
.246 |
.0 |
.04 |
.499 |
.481 |
.011 |
.017 |
.074 |
.381 |
.0 |
.0 |
.011 |
.001 |
.007 |
.002 |
.072 |
.001 |
.388 |
.002 |
.008 |
.008 |
.144 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.012 |
.009 |
.114 |
.055 |
.023 |
.0 |
.0 |
.001 |
.109 |
.002 |
.0 |
.001 |
.0 |
.001 |
.002 |
.004 |
.063 |
.002 |
.001 |
.002 |
.001 |
.002 |
.056 |
.097 |
.087 |
.062 |
.032 |
.019 |
.001 |
.015 |
.093 |
.009 |
.081 |
.03 |
.608 |
.001 |
.015 |
.024 |
.011 |
.001 |
.023 |
.037 |
.007 |
.448 |
.0 |
.007 |
.009 |
.021 |
.032 |
.0 |
.016 |
.0 |
.0 |
.172 |
.002 |
.01 |
.068 |
.003 |
.006 |
.001 |
.021 |
.008 |
.062 |
.003 |
.002 |
.011 |
.013 |
-- |
-- |
-- |
-- |
.162 |
.968 |
.988 |
.001 |
.001 |
.007 |
-- |
.019 |
.003 |
.142 |
.0 |
.001 |
.494 |
.07 |
.052 |
.001 |
.001 |
.0 |
.002 |
.003 |
.0 |
.001 |
.0 |
.474 |
.401 |
.001 |
.0 |
.002 |
.0 |
.001 |
.0 |
.531 |
.628 |
.002 |
.015 |
.0 |
.009 |
.002 |
.0 |
.983 |
.009 |
.011 |
.069 |
.004 |
.003 |
.014 |
.001 |
.002 |
.998 |
.961 |
.991 |
.535 |
1.0 |
1.0 |
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
T |
C |
C |
G |
G |
T |
A |
T |
T |
G |
T |
C |
G |
C |
T |
A |
A |
G |
C |
8 |
T |
G |
C |
T |
2 |
G |
C |
A |
A |
G |
G |
T |
C |
T |
G |
C |
3 |
T |
G |
C |
A |
C |
C |
A |
G |
C |
A |
6 |
T |
A |
C |
T |
A |
T |
T |
C |
T |
G |
G |
G |
G |
T |
G |
T |
A |
A |
A |
T |
G |
A |
2 |
T |
C |
T |
C |
G |
A |
T |
C |
C |
A |
T |
T |
3 |
G |
A |
A |
T |
T |
C |
A |
T |
C |
A |
C |
G |
C |
2 |
A |
C |
G |
A |
C |
3 |
T |
T |
T |
C |
C |
T |
T |
A |
A |
C |
C |
T |
C |
G |
C |
C |
C |
T |
G |
A |
G |
T |
A |
C |
19 |
G |
C |
T |
C |
G |
T |
G |
G |
T |
T |
C |
A |
A |
2 |
T |
C |
A |
G |
C |
T |
T |
C |
A |
C |
C |
A |
T |
A |
T |
A |
A |
G |
C |
A |
G |
C |
T |
G |
T |
A |
A |
C |
G |
T |
G |
G |
C |
2 |
A |
A |
T |
T |
C |
A |
A |
A |
T |
A |
C |
G |
G |
A |
C |
G |
A |
C |
G |
T |
T |
C |
A |
T |
C |
C |
C |
C |
G |
C |
C |
G |
G |
G |
A |
T |
T |
A |
G |
G |
C |
T |
C |
A |
8 |
G |
T |
C |
C |
T |
C |
T |
C |
C |
2 |
G |
C |
G |
T |
G |
C |
T |
T |
C |
T |
3 |
A |
A |
T |
A |
C |
C |
T |
A |
G |
T |
T |
T |
G |
C |
C |
3 |
T |
C |
G |
A |
T |
T |
G |
A |
A |
C |
G |
G |
A |
T |
C |
T |
G |
A |
G |
C |
T |
T |
G |
C |
G |
A |
T |
A |
T |
G |
T |
G |
A |
T |
A |
2 |
C |
C |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
C
|
-
|
T
|
T
|
A
|
C
|
C
|
C
|
C
|
A
|
C
|
2
|
A
|
T
|
T/G
|
G
|
G
|
T
|
G
|
8/-
|
C
|
A
|
A
|
G
|
-
|
A
|
C/T
|
G
|
C
|
T
|
A
|
-
|
A
|
-
|
G/A
|
C/T
|
-
|
C
|
A
|
C/T
|
T
|
T
|
T
|
G
|
G/A
|
T
|
G
|
-
|
2
|
G
|
G
|
C
|
-
|
T/6
|
T/A
|
T
|
C
|
A
|
A
|
T
|
G/A
|
C
|
T
|
3
|
G
|
G
|
G
|
C
|
A
|
G
|
-
|
C
|
T
|
C
|
A
|
A
|
2
|
C
|
T
|
A
|
G
|
2
|
C
|
-
|
2
|
T
|
C
|
C
|
C
|
T
|
T
|
C
|
T
|
A/3
|
G
|
A
|
G
|
2/-
|
2
|
T
|
A
|
C
|
A
|
-
|
G
|
C
|
C
|
T
|
T
|
C
|
C
|
C
|
-
|
G
|
A
|
5
|
-
|
G/T
|
A
|
T
|
T
|
C
|
T
|
G
|
4
|
-
|
A/G
|
T
|
19/-
|
A
|
C/2
|
C
|
A
|
A
|
A
|
C
|
A
|
C
|
A
|
T
|
A/C
|
G
|
-
|
C
|
-
|
T
|
A
|
C/2
|
C
|
-
|
T
|
G
|
T
|
T
|
T
|
C
|
A/G
|
G
|
T
|
-
|
G/A
|
C/T
|
-
|
G/A
|
T
|
T/C
|
G/A
|
C
|
G
|
G
|
T
|
A
|
C
|
C
|
T
|
T
|
-
|
C
|
G
|
C
|
G
|
A
|
G
|
G
|
T
|
A
|
G
|
T
|
A
|
A
|
G
|
T
|
A
|
G
|
T
|
A
|
-
|
A
|
T
|
G
|
C
|
A
|
A
|
T
|
T
|
A
|
T
|
T
|
A
|
A
|
T
|
G
|
C
|
2
|
G
|
A
|
A
|
T
|
A
|
C/T
|
A/G
|
8/-
|
C
|
C
|
T
|
A
|
T/C
|
T
|
G
|
A
|
T
|
-
|
A
|
C/T
|
A
|
A
|
T
|
T
|
T/4
|
T/C
|
T
|
C
|
-
|
G
|
T
|
-
|
-
|
T
|
A
|
C
|
G
|
A
|
C
|
C
|
G
|
T
|
C/T
|
-
|
-
|
T/C
|
G
|
A
|
3/AT
|
C
|
T/C
|
G/A
|
G
|
T
|
2
|
G/A
|
A
|
A/G
|
T/C
|
C/A
|
C
|
T
|
T
|
G/T
|
T
|
C
|
C
|
A
|
T
|
A
|
T
|
-
|
G
|
C
|
A
|
3
|
A
|
T
|
C
|
-
|
-
|
T
|
T
|
T
|
|