|
.031 |
.03 |
.0 |
.004 |
.029 |
.07 |
.171 |
.0 |
.036 |
.059 |
.023 |
-- |
-- |
.074 |
.003 |
.007 |
.039 |
.005 |
.99 |
.986 |
-- |
-- |
-- |
.001 |
-- |
-- |
.076 |
.298 |
.025 |
.053 |
.516 |
.189 |
.344 |
.001 |
.046 |
.114 |
.103 |
.007 |
.055 |
.15 |
-- |
-- |
.029 |
.235 |
.011 |
.022 |
.466 |
.013 |
.057 |
.634 |
.011 |
.064 |
.043 |
.042 |
.557 |
.006 |
.004 |
.0 |
.0 |
.014 |
.037 |
.814 |
.037 |
.0 |
.17 |
.006 |
.008 |
.117 |
-- |
.131 |
.152 |
.003 |
.053 |
.232 |
.233 |
.234 |
.083 |
.014 |
.0 |
.923 |
.001 |
.003 |
.007 |
.027 |
.055 |
.154 |
.003 |
.005 |
.004 |
.0 |
.0 |
.01 |
.046 |
.224 |
.249 |
.014 |
.002 |
.002 |
.002 |
.036 |
.204 |
.218 |
.923 |
.004 |
.066 |
.032 |
.004 |
.023 |
.292 |
.236 |
.0 |
.002 |
.326 |
.907 |
.007 |
.916 |
.091 |
.002 |
.006 |
.0 |
.0 |
.118 |
.013 |
.02 |
.003 |
.12 |
.015 |
.001 |
.004 |
.0 |
.0 |
.003 |
.018 |
.033 |
.041 |
.002 |
.01 |
.001 |
.002 |
.011 |
.312 |
.003 |
.006 |
.0 |
.001 |
.03 |
.473 |
.001 |
.046 |
.002 |
.022 |
-- |
.002 |
.002 |
-- |
-- |
.048 |
.004 |
.04 |
.032 |
.017 |
.001 |
.006 |
.576 |
.126 |
.103 |
.715 |
.001 |
.005 |
.023 |
.001 |
.008 |
.711 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.01 |
-- |
.044 |
.142 |
.006 |
.034 |
.215 |
.29 |
.37 |
.658 |
.852 |
.073 |
-- |
-- |
-- |
.181 |
.189 |
.003 |
.005 |
.008 |
.036 |
.008 |
.0 |
.133 |
.056 |
.015 |
.0 |
.0 |
.015 |
.002 |
.002 |
.016 |
.003 |
.008 |
.007 |
.001 |
.0 |
.002 |
.0 |
.001 |
.001 |
.024 |
.001 |
.001 |
.998 |
-- |
.094 |
.191 |
.157 |
.074 |
.357 |
.013 |
.004 |
.0 |
.003 |
.013 |
.01 |
.002 |
.001 |
.0 |
.004 |
.002 |
.003 |
.071 |
.001 |
.002 |
.043 |
.121 |
.963 |
.004 |
.03 |
.051 |
.049 |
.049 |
.623 |
.022 |
.018 |
.008 |
.034 |
.035 |
.028 |
.001 |
.999 |
.727 |
1.0 |
.672 |
.029 |
.008 |
.022 |
.002 |
.023 |
.095 |
.628 |
.0 |
.034 |
.024 |
.001 |
.001 |
.145 |
.622 |
.001 |
.014 |
.001 |
.008 |
.012 |
.039 |
.005 |
.001 |
.179 |
.179 |
.034 |
.347 |
.012 |
.0 |
.004 |
.022 |
.112 |
.003 |
.009 |
.004 |
.013 |
.0 |
.002 |
.011 |
.001 |
.0 |
.046 |
.002 |
.001 |
.006 |
.002 |
.001 |
.007 |
.002 |
.001 |
.001 |
.003 |
.001 |
.0 |
.0 |
.006 |
.034 |
.006 |
.01 |
.011 |
.034 |
.031 |
.557 |
.002 |
.038 |
.007 |
.024 |
.009 |
.115 |
.001 |
.001 |
.0 |
.0 |
.008 |
.001 |
-- |
.222 |
.128 |
.226 |
.328 |
.252 |
.092 |
.002 |
.0 |
.008 |
.088 |
.001 |
.003 |
.0 |
.0 |
.0 |
.007 |
.019 |
.044 |
-- |
-- |
.001 |
.68 |
.0 |
.074 |
.013 |
.199 |
.362 |
.062 |
-- |
.036 |
.001 |
.001 |
.0 |
.068 |
.002 |
.882 |
.261 |
.007 |
.007 |
.028 |
.227 |
.161 |
-- |
.001 |
.04 |
.008 |
.008 |
.635 |
.057 |
.255 |
.98 |
.005 |
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
Kcnq1
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
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--
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--
|
--
|
--
|
--
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--
|
--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
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--
|
--
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--
|
--
|
--
|
--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
A |
T |
6 |
A |
C |
C |
C |
C |
G |
T |
A |
4 |
A |
T |
G |
A |
T |
4 |
2 |
G |
8 |
6 |
14 |
T |
A |
A |
4 |
G |
C |
2 |
C |
A |
G |
2 |
T |
T |
G |
T |
4 |
T |
2 |
T |
C |
G |
T |
A |
C |
C |
G |
T |
C |
A |
G |
C |
A |
T |
G |
G |
G |
72 |
6 |
G |
A |
A |
T |
A |
T |
C |
T |
G |
A |
C |
6 |
4 |
2 |
C |
C |
T |
G |
G |
T |
G |
6 |
A |
C |
C |
4 |
C |
G |
4 |
A |
T |
A |
A |
C |
A |
A |
A |
T |
C |
C |
T |
G |
T |
G |
T |
C |
T |
12 |
G |
T |
T |
T |
G |
G |
A |
T |
G |
G |
T |
G |
T |
C |
T |
C |
T |
A |
T |
T |
A |
G |
A |
T |
A |
G |
G |
G |
T |
T |
T |
G |
T |
T |
T |
A |
A |
T |
G |
C |
T |
4 |
G |
A |
2 |
G |
C |
C |
2 |
A |
C |
T |
C |
T |
C |
T |
T |
C |
G |
T |
T |
G |
T |
A |
C |
G |
A |
C |
A |
C |
G |
C |
C |
C |
A |
4 |
12 |
C |
2 |
A |
G |
G |
T |
C |
G |
T |
T |
C |
T |
C |
T |
4 |
4 |
T |
A |
G |
T |
C |
A |
A |
T |
T |
T |
G |
T |
A |
G |
T |
C |
A |
C |
2 |
A |
4 |
G |
T |
T |
T |
C |
T |
G |
G |
C |
A |
C |
A |
G |
G |
G |
A |
C |
T |
G |
C |
C |
C |
A |
G |
T |
T |
A |
G |
A |
C |
C |
T |
T |
C |
G |
C |
C |
T |
3 |
T |
C |
T |
G |
C |
C |
C |
C |
G |
C |
C |
C |
A |
A |
G |
A |
A |
G |
C |
5 |
G |
G |
C |
G |
G |
A |
T |
G |
T |
G |
A |
C |
2 |
G |
C |
G |
A |
C |
G |
14 |
12 |
A |
A |
A |
T |
G |
T |
A |
T |
T |
T |
C |
4 |
T |
G |
G |
T |
C |
C |
G |
C |
T |
T |
A |
A |
G |
A |
A |
T |
G |
A |
T |
20 |
A |
G |
G |
T |
C |
C |
G |
A |
A |
A |
A |
4 |
A |
G |
C |
G |
T |
C |
A |
A |
T |
T |
T |
T |
6 |
T |
A |
A |
G |
G |
G |
T |
A |
T |
G |
T |
A |
2 |
T |
A |
C |
G |
C |
T |
G |
T |
76 |
C |
C |
A |
T |
A |
C |
G |
G |
C |
4 |
G |
T |
G |
C |
C |
A |
A |
A |
A |
C |
A |
C |
C |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
G
|
10/12
|
-
|
9
|
-
|
T
|
T
|
2
|
C
|
C
|
G
|
-
|
G
|
T/3
|
2
|
G
|
C
|
4/-
|
2/-
|
A
|
8/-
|
6/-
|
-
|
2
|
-
|
G
|
-
|
A
|
3
|
2/-
|
T
|
T
|
C
|
-
|
C
|
G
|
T
|
C
|
-
|
-
|
-
|
C
|
-
|
A
|
C
|
G
|
T
|
T
|
G/3
|
A
|
A
|
C
|
A
|
-
|
T
|
C
|
-
|
-
|
-
|
-
|
-
|
C
|
G
|
G
|
A
|
G
|
-
|
A
|
A
|
A
|
G
|
T
|
6/-
|
4/-
|
2/-
|
T
|
G
|
2
|
A
|
A
|
A
|
G/-
|
-
|
G
|
T
|
A
|
-
|
T
|
A
|
-
|
3
|
C
|
G
|
3
|
5
|
G
|
G
|
2
|
11
|
3
|
G
|
C
|
A
|
A
|
T
|
G
|
T
|
T/-
|
12/-
|
A
|
A
|
-
|
C
|
A
|
A
|
2
|
C
|
A
|
C
|
G
|
103
|
19
|
A
|
34
|
T
|
C
|
G
|
C
|
C
|
G
|
A
|
G
|
C
|
G
|
25
|
T
|
A
|
C
|
10
|
C
|
T
|
C
|
5/3
|
C
|
G
|
G
|
C
|
A
|
T
|
T/5
|
-
|
A
|
T
|
-
|
8
|
T
|
G
|
2/-
|
T
|
C/13
|
C
|
3
|
25
|
T
|
G
|
3
|
3
|
T
|
C
|
C
|
T
|
C
|
5
|
A
|
-
|
17
|
T
|
-
|
T
|
A
|
-
|
T
|
4
|
T
|
-
|
-
|
2
|
2/-
|
A/-
|
-
|
G/2
|
88
|
2
|
T
|
C
|
G
|
CT/3
|
22/24
|
T
|
3
|
-
|
-
|
-
|
G
|
3
|
-
|
4/3
|
G
|
T
|
-
|
5
|
13
|
A
|
G
|
G
|
2
|
6
|
3
|
-
|
T
|
-
|
G
|
-
|
A
|
2
|
2
|
2
|
T
|
8
|
C
|
A
|
A
|
T
|
G
|
G
|
A
|
A
|
A
|
2
|
3
|
2
|
A
|
T
|
T
|
T
|
-
|
2
|
3
|
C
|
G
|
A
|
T
|
T
|
3
|
C
|
A
|
T
|
A
|
T
|
T
|
C
|
-
|
5
|
T
|
2
|
T
|
2
|
2
|
2
|
2
|
A
|
A
|
T
|
A
|
G
|
G
|
A
|
T
|
2
|
T
|
T
|
-
|
T
|
3/GT
|
2
|
A
|
A
|
17/5
|
C
|
A
|
C
|
3
|
G
|
T
|
-
|
2
|
T
|
A
|
G
|
T
|
A
|
14/-
|
12/-
|
?
|
T
|
G
|
4
|
A
|
61
|
G
|
C
|
A
|
2
|
T
|
-
|
C
|
A
|
T
|
C
|
7
|
A
|
A
|
G
|
A
|
C
|
G
|
C
|
A
|
-
|
104
|
G
|
A
|
G
|
G
|
-
|
G
|
A
|
A
|
C
|
7
|
A
|
A
|
G
|
G
|
G
|
10
|
-
|
G
|
A
|
G
|
A
|
A
|
T
|
C
|
2
|
C
|
11
|
C
|
-
|
6/-
|
T/-
|
G
|
4
|
2
|
A
|
A
|
A
|
G
|
C
|
A
|
C
|
3/AT
|
2/-
|
T/-
|
G
|
T
|
A
|
A
|
T/-
|
A
|
C
|
-
|
C/2
|
C/3
|
3
|
T/2
|
G
|
13
|
A
|
2
|
C/-
|
-
|
-
|
2
|
A
|
-
|
3
|
G
|
-
|
C
|
A/-
|
2
|
G
|
T
|
CA/3
|
G
|
|