|
.958 |
.001 |
.0 |
.0 |
.0 |
.0 |
.997 |
.094 |
.001 |
.0 |
.0 |
.006 |
-- |
-- |
.013 |
.002 |
.035 |
-- |
-- |
-- |
.746 |
.201 |
.04 |
.079 |
.021 |
.067 |
.127 |
.055 |
.191 |
.016 |
.057 |
.068 |
.052 |
.237 |
.168 |
-- |
-- |
-- |
.003 |
.003 |
.005 |
.002 |
.008 |
.754 |
.014 |
-- |
-- |
-- |
-- |
.022 |
.033 |
.002 |
.259 |
.006 |
.015 |
.017 |
.001 |
.01 |
.073 |
.05 |
.024 |
.108 |
.054 |
.002 |
.712 |
.009 |
1.0 |
.0 |
.005 |
.084 |
.002 |
.197 |
.953 |
.0 |
-- |
.002 |
.006 |
.07 |
.009 |
.001 |
.315 |
.18 |
.097 |
.018 |
.022 |
.031 |
.003 |
.014 |
.006 |
.989 |
.0 |
.004 |
.348 |
.006 |
.019 |
.013 |
.017 |
.03 |
.132 |
.128 |
.069 |
.0 |
.007 |
.002 |
.052 |
.0 |
.189 |
.58 |
.007 |
.145 |
.001 |
.053 |
.731 |
.004 |
.016 |
.022 |
.005 |
.038 |
.166 |
.443 |
.09 |
-- |
-- |
.641 |
.671 |
.102 |
.002 |
.011 |
.002 |
.003 |
.005 |
.008 |
.003 |
.002 |
.127 |
.007 |
.001 |
.002 |
1.0 |
.374 |
.007 |
.002 |
.002 |
.0 |
.0 |
.008 |
.001 |
.037 |
.004 |
.003 |
.004 |
.0 |
.001 |
.005 |
.005 |
.007 |
.002 |
.002 |
.0 |
.0 |
.014 |
.007 |
.003 |
.0 |
.001 |
.001 |
.052 |
.092 |
.078 |
.031 |
.315 |
.02 |
.011 |
.0 |
.028 |
.023 |
.025 |
.01 |
.005 |
.0 |
.469 |
.066 |
.378 |
-- |
-- |
-- |
.043 |
.019 |
.005 |
.005 |
.051 |
.694 |
.002 |
.0 |
.0 |
-- |
.268 |
.008 |
.0 |
.001 |
.525 |
.02 |
.101 |
.08 |
.09 |
.065 |
.099 |
.002 |
-- |
-- |
-- |
.231 |
.01 |
.312 |
.001 |
.003 |
.017 |
.078 |
.057 |
.006 |
.0 |
.003 |
.008 |
.002 |
.02 |
.154 |
.706 |
.014 |
.001 |
.038 |
.031 |
.084 |
.005 |
.031 |
.015 |
.343 |
.175 |
.518 |
.018 |
.086 |
.155 |
.182 |
.75 |
.004 |
.002 |
.013 |
.0 |
.451 |
.007 |
.057 |
.007 |
.294 |
-- |
-- |
.003 |
.002 |
.082 |
.003 |
.0 |
.003 |
.083 |
.657 |
.217 |
.001 |
.136 |
.015 |
.026 |
.133 |
.195 |
.187 |
.043 |
.0 |
.001 |
.002 |
.0 |
.008 |
.008 |
.0 |
.0 |
.023 |
.0 |
.0 |
-- |
.02 |
.374 |
.029 |
.079 |
-- |
-- |
.073 |
-- |
-- |
.726 |
.342 |
.012 |
.208 |
.012 |
.004 |
.004 |
-- |
.005 |
.43 |
.037 |
.015 |
.036 |
.0 |
.049 |
.202 |
.008 |
.152 |
.001 |
.903 |
.68 |
.04 |
.001 |
.014 |
.495 |
.014 |
.033 |
.001 |
.173 |
.001 |
.012 |
.196 |
.079 |
-- |
-- |
.003 |
.295 |
.047 |
.312 |
.005 |
.124 |
.014 |
.009 |
.338 |
.079 |
.112 |
.026 |
.067 |
.626 |
-- |
-- |
-- |
.038 |
.014 |
.27 |
.855 |
.0 |
.055 |
.03 |
.002 |
.003 |
.094 |
1.0 |
.001 |
.004 |
.011 |
.0 |
.567 |
.196 |
.002 |
.003 |
-- |
-- |
-- |
-- |
.032 |
.083 |
-- |
-- |
-- |
.023 |
.04 |
.083 |
.035 |
.0 |
.002 |
.003 |
.001 |
.464 |
.027 |
.0 |
.001 |
.002 |
.019 |
.001 |
.014 |
.001 |
.0 |
.046 |
.003 |
.013 |
.009 |
.01 |
.001 |
.004 |
.001 |
.007 |
.0 |
.157 |
.132 |
.001 |
.352 |
-- |
-- |
-- |
.007 |
.002 |
.008 |
.015 |
.12 |
.003 |
.001 |
.001 |
.002 |
.07 |
.078 |
.031 |
.158 |
.322 |
.0 |
.013 |
.018 |
.01 |
.199 |
.186 |
.161 |
.001 |
.004 |
.0 |
.069 |
-- |
.584 |
.016 |
.452 |
.004 |
.005 |
.049 |
.011 |
.052 |
.027 |
.003 |
.049 |
.023 |
.0 |
.097 |
.095 |
.0 |
.032 |
.001 |
.001 |
.002 |
.003 |
.002 |
.001 |
.002 |
.004 |
.108 |
.0 |
.0 |
.002 |
.002 |
.0 |
.0 |
.023 |
.307 |
.005 |
.001 |
.008 |
.0 |
.001 |
.0 |
.002 |
.014 |
.001 |
.012 |
.009 |
.121 |
.152 |
.013 |
.044 |
.006 |
.033 |
.001 |
.0 |
.005 |
.0 |
.015 |
.003 |
.168 |
.0 |
.002 |
.011 |
.002 |
.01 |
.136 |
.001 |
.022 |
.018 |
.0 |
.001 |
.005 |
.015 |
-- |
-- |
.002 |
.005 |
.007 |
.13 |
.012 |
.01 |
.005 |
.705 |
.111 |
.011 |
.0 |
.022 |
.0 |
.004 |
.0 |
.0 |
.001 |
.002 |
.001 |
.004 |
.009 |
.008 |
.001 |
.01 |
.198 |
.0 |
.643 |
.159 |
.28 |
.027 |
.03 |
.006 |
.001 |
.003 |
.008 |
.017 |
-- |
.001 |
.002 |
.02 |
.158 |
.623 |
-- |
.052 |
.005 |
.145 |
.692 |
.086 |
.014 |
.046 |
.003 |
.0 |
.0 |
.0 |
.989 |
.001 |
.0 |
.045 |
.031 |
.055 |
.016 |
.03 |
.006 |
.001 |
.003 |
.001 |
.416 |
.003 |
.003 |
.001 |
.002 |
.001 |
.0 |
.009 |
.024 |
-- |
.03 |
.021 |
.005 |
-- |
.02 |
.212 |
.002 |
.026 |
.034 |
.004 |
.011 |
.009 |
.004 |
.001 |
.002 |
.001 |
.002 |
.009 |
.002 |
.015 |
.02 |
.0 |
.174 |
.038 |
.477 |
.623 |
.144 |
.01 |
.006 |
.031 |
.056 |
-- |
-- |
-- |
.13 |
.002 |
.006 |
.003 |
.48 |
.135 |
.04 |
.019 |
.034 |
.0 |
.0 |
.005 |
.0 |
.001 |
.001 |
.003 |
.001 |
.001 |
.833 |
.444 |
-- |
-- |
.005 |
.008 |
.013 |
.003 |
.06 |
.074 |
.083 |
.101 |
.004 |
.001 |
.0 |
.017 |
.0 |
.048 |
.014 |
.003 |
.0 |
.003 |
.001 |
.001 |
.001 |
.0 |
.002 |
.0 |
.995 |
.004 |
.176 |
.986 |
.964 |
|
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Hdac4
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|
3 |
A |
A |
G |
A |
A |
2 |
T |
C |
A |
C |
G |
C |
A |
C |
39 |
C |
G |
T |
G |
T |
A |
G |
A |
G |
G |
G |
G |
2 |
2 |
A |
C |
C |
T |
C |
G |
G |
C |
G |
C |
C |
C |
C |
C |
A |
T |
C |
G |
G |
A |
C |
C |
C |
T |
G |
C |
G |
G |
G |
G |
G |
C |
C |
T |
C |
C |
T |
T |
G |
4 |
A |
A |
C |
T |
C |
T |
G |
A |
A |
T |
G |
T |
C |
C |
6 |
4 |
A |
A |
G |
T |
C |
3 |
C |
A |
C |
G |
T |
G |
A |
C |
C |
T |
G |
T |
T |
A |
C |
G |
G |
T |
A |
A |
G |
T |
A |
C |
T |
G |
G |
G |
A |
A |
G |
T |
A |
C |
A |
A |
T |
C |
C |
A |
C |
A |
C |
T |
A |
G |
T |
T |
T |
G |
A |
G |
T |
T |
T |
13 |
T |
4 |
T |
C |
C |
G |
A |
A |
T |
G |
G |
A |
G |
A |
T |
T |
G |
G |
C |
A |
T |
C |
G |
T |
G |
C |
2 |
C |
T |
A |
T |
T |
69 |
C |
C |
A |
T |
A |
G |
A |
T |
G |
T |
T |
G |
G |
C |
2 |
T |
T |
C |
C |
G |
C |
C |
C |
T |
C |
C |
G |
G |
A |
A |
C |
A |
A |
A |
G |
T |
G |
G |
G |
C |
C |
T |
C |
A |
A |
T |
T |
C |
C |
G |
C |
T |
T |
A |
C |
T |
A |
16 |
G |
G |
G |
A |
C |
A |
T |
T |
A |
G |
C |
T |
G |
C |
C |
G |
A |
G |
G |
A |
T |
T |
G |
G |
C |
T |
C |
C |
G |
A |
A |
G |
T |
T |
C |
T |
C |
G |
C |
T |
C |
A |
C |
G |
A |
G |
C |
G |
C |
A |
C |
G |
G |
117 |
A |
G |
C |
C |
A |
G |
C |
G |
C |
C |
G |
A |
7 |
T |
T |
G |
A |
T |
T |
C |
A |
G |
A |
C |
G |
G |
C |
A |
C |
G |
T |
C |
A |
G |
T |
C |
G |
G |
C |
T |
G |
C |
C |
A |
T |
A |
G |
A |
T |
2 |
A |
A |
T |
G |
C |
G |
9 |
7 |
C |
7 |
T |
T |
G |
2 |
T |
A |
A |
A |
G |
G |
A |
G |
G |
A |
G |
C |
T |
C |
8 |
T |
C |
G |
C |
G |
8 |
6 |
2 |
A |
G |
A |
G |
C |
A |
C |
C |
C |
T |
A |
T |
C |
9 |
T |
A |
C |
A |
G |
C |
T |
A |
G |
C |
G |
T |
G |
T |
A |
T |
A |
A |
T |
G |
G |
G |
T |
A |
T |
T |
C |
C |
T |
C |
A |
T |
G |
2 |
2 |
G |
T |
T |
A |
C |
C |
C |
6 |
4 |
C |
T |
C |
C |
G |
C |
C |
G |
G |
C |
C |
G |
T |
A |
2 |
T |
3 |
2 |
T |
A |
G |
A |
A |
2 |
4 |
G |
A |
T |
G |
C |
C |
C |
A |
C |
G |
T |
T |
T |
T |
C |
T |
C |
T |
4 |
2 |
G |
T |
A |
A |
C |
T |
25 |
G |
A |
T |
C |
A |
G |
31 |
C |
C |
C |
G |
G |
G |
C |
A |
A |
T |
6 |
A |
A |
T |
G |
A |
A |
T |
T |
T |
G |
A |
G |
G |
C |
G |
A |
T |
C |
T |
A |
T |
C |
C |
G |
T |
C |
4 |
C |
A |
16 |
C |
11 |
G |
C |
C |
G |
A |
C |
C |
G |
G |
T |
A |
C |
T |
G |
T |
T |
C |
C |
T |
C |
G |
T |
C |
G |
A |
T |
A |
C |
A |
T |
T |
A |
G |
G |
A |
G |
A |
2 |
T |
T |
C |
A |
A |
C |
T |
C |
A |
24 |
C |
C |
4 |
G |
A |
A |
C |
A |
6 |
A |
C |
T |
A |
T |
C |
G |
A |
G |
G |
A |
A |
A |
C |
G |
C |
A |
25 |
23 |
G |
2 |
A |
G |
A |
G |
A |
G |
T |
A |
T |
A |
C |
G |
C |
C |
A |
T |
T |
G |
G |
T |
T |
T |
G |
A |
A |
6 |
4 |
A |
A |
G |
G |
C |
G |
T |
A |
C |
A |
C |
T |
3 |
C |
C |
C |
T |
G |
C |
G |
G |
G |
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
-
|
9
|
G
|
A
|
C
|
G
|
-
|
C
|
T
|
G
|
T
|
A
|
5
|
G
|
T
|
-
|
A
|
T
|
C
|
C
|
23
|
G
|
A
|
G
|
T
|
C
|
A
|
A
|
-
|
-
|
G
|
T
|
T
|
A
|
T
|
C
|
A
|
G
|
A
|
T
|
2
|
2
|
T
|
G
|
G
|
T/2
|
3
|
33
|
11
|
T
|
T
|
T
|
T
|
G
|
T
|
T
|
A
|
T
|
A
|
A
|
A
|
T
|
T
|
C
|
T
|
T
|
2
|
C
|
C
|
4/-
|
19
|
T
|
T
|
C
|
8
|
2
|
26/28
|
G
|
G
|
A
|
A
|
A
|
T
|
3
|
6/-
|
4/-
|
G
|
G
|
A
|
C
|
2
|
-
|
T
|
G
|
T
|
T
|
2
|
2
|
G
|
T
|
A
|
C
|
2
|
C
|
C
|
G
|
T
|
A
|
A
|
A
|
G
|
G
|
T
|
G
|
T
|
T
|
C
|
A
|
A
|
A
|
G
|
G
|
3
|
-
|
G
|
T
|
T
|
G
|
G
|
T
|
-
|
C
|
A
|
C
|
T
|
C
|
G
|
A
|
G
|
C
|
C
|
A
|
G
|
A
|
C
|
C
|
C
|
-
|
C
|
-
|
A
|
T
|
T
|
T
|
G
|
C
|
C
|
A
|
T
|
G
|
T
|
G
|
G
|
C
|
C
|
T
|
T
|
C
|
C
|
A
|
A
|
A
|
A
|
T
|
-
|
2
|
A
|
G
|
G
|
G
|
-
|
T
|
T
|
T
|
-
|
G
|
A
|
2
|
C
|
A
|
C
|
C
|
10
|
7
|
T
|
2/-
|
C
|
G
|
T
|
C/6
|
A
|
T
|
T
|
A
|
C
|
T
|
A
|
A
|
2
|
A/-
|
C
|
T
|
G
|
T
|
G
|
A
|
A
|
A
|
A
|
-
|
G
|
T
|
-
|
2
|
C
|
G
|
C
|
C
|
T
|
T
|
A
|
T
|
C
|
C
|
G
|
T
|
T/25
|
-
|
-
|
A
|
T
|
3
|
T
|
G
|
G
|
C
|
C
|
-
|
A
|
A
|
C
|
C
|
T
|
C/-
|
A
|
G
|
3
|
A
|
G
|
C
|
C
|
T
|
C
|
5
|
C
|
T
|
T
|
T
|
G
|
C
|
A
|
C
|
C
|
T
|
C
|
T
|
A
|
A
|
2
|
T
|
G
|
A
|
3
|
C
|
2
|
A
|
A
|
A
|
9
|
T
|
4
|
A
|
-
|
-
|
A
|
T
|
A
|
T
|
A
|
T
|
A
|
T
|
G
|
A
|
G
|
-
|
C
|
C
|
T
|
G
|
C
|
C
|
T
|
T
|
C
|
T
|
T
|
2
|
2
|
T
|
-
|
T
|
-
|
C
|
T
|
G
|
A
|
2
|
T
|
T
|
A
|
T
|
C
|
A
|
T
|
G
|
16
|
C
|
T
|
A
|
G
|
C
|
2/-
|
-
|
G
|
G
|
C
|
T
|
C
|
9/-
|
-
|
T
|
-
|
G
|
-
|
3
|
-
|
C
|
T
|
5
|
G
|
7
|
C
|
43
|
C
|
C
|
T
|
7
|
T
|
T/7
|
C/-
|
8/-
|
C
|
T
|
A
|
G
|
C
|
8/-
|
-
|
-
|
2
|
A
|
G
|
T
|
2
|
T
|
T
|
G
|
T
|
C
|
G
|
C
|
T
|
-
|
A
|
5
|
T
|
G
|
A
|
A
|
C
|
19
|
A
|
T
|
?
|
2
|
85
|
C
|
T
|
11
|
T
|
G
|
C
|
A
|
A
|
A
|
C
|
-
|
C
|
C
|
T
|
T
|
-
|
-
|
G
|
6
|
C
|
-
|
-
|
A
|
C
|
C
|
2
|
G
|
T
|
T
|
6/-
|
-
|
G
|
C
|
T
|
A
|
-
|
T
|
T
|
A
|
A
|
A
|
T
|
A
|
A
|
4
|
2/-
|
A
|
3/-
|
-
|
C
|
G
|
A
|
4
|
8
|
-
|
-
|
A
|
G
|
C
|
A
|
A
|
T
|
-
|
C
|
-
|
A
|
-
|
C
|
A
|
C
|
T
|
C
|
4
|
C
|
4/-
|
2/-
|
A
|
C
|
G
|
-
|
T
|
-
|
-
|
T
|
18
|
C
|
G
|
G
|
A
|
-
|
T
|
T
|
T
|
T
|
A
|
A
|
T
|
9
|
7
|
C
|
-
|
G
|
2
|
C
|
A
|
9
|
G
|
2
|
C
|
C
|
A
|
G
|
A
|
C
|
A
|
9
|
T
|
C
|
T
|
C
|
G
|
G
|
-
|
T
|
A
|
C
|
T
|
-
|
G
|
T
|
16/-
|
C/-
|
11/-
|
A
|
T
|
T
|
A
|
G
|
T
|
T
|
A
|
-
|
G
|
G
|
T
|
C
|
T
|
C
|
C
|
2
|
A
|
C
|
T
|
2
|
A
|
T
|
A
|
G
|
C
|
G
|
T
|
G
|
C
|
A
|
G
|
A
|
A
|
G
|
A
|
G
|
-
|
10
|
C
|
T
|
T
|
3
|
G
|
C
|
T
|
C
|
24/-
|
A
|
T
|
-
|
A
|
-
|
G
|
T
|
G
|
-
|
C
|
G
|
-
|
G
|
C
|
-
|
A
|
-
|
A
|
C
|
G
|
17
|
G
|
T
|
C
|
T
|
-
|
25/-
|
23/-
|
A
|
2/-
|
A/-
|
C
|
C
|
A
|
G
|
T
|
C
|
G
|
G
|
G
|
T
|
A
|
T
|
2
|
-
|
G
|
12
|
C
|
A
|
2
|
C
|
C
|
A
|
3
|
G
|
6/-
|
4/-
|
G
|
G
|
A
|
2
|
G
|
2
|
C
|
G
|
T
|
C
|
T
|
-
|
-
|
T
|
T
|
10
|
C
|
2
|
A
|
A
|
2
|
-
|
|