|
.864 |
.001 |
.823 |
.113 |
.201 |
.002 |
.063 |
.008 |
.011 |
.11 |
.013 |
.662 |
.049 |
.07 |
.01 |
-- |
.032 |
.043 |
.076 |
.347 |
.002 |
.278 |
-- |
.013 |
-- |
-- |
.449 |
.164 |
.118 |
-- |
.81 |
.003 |
.197 |
.001 |
.001 |
.01 |
.314 |
.384 |
.571 |
.859 |
.202 |
.454 |
.01 |
.0 |
.0 |
-- |
-- |
.076 |
.009 |
.694 |
.002 |
.002 |
.009 |
.149 |
.02 |
.011 |
-- |
-- |
.114 |
-- |
.011 |
.017 |
.624 |
.01 |
-- |
-- |
-- |
.006 |
.877 |
.441 |
.085 |
.077 |
.014 |
.401 |
.19 |
-- |
.004 |
.004 |
.842 |
.089 |
.236 |
.011 |
.061 |
.074 |
.139 |
.149 |
-- |
-- |
.143 |
.16 |
.017 |
.003 |
.012 |
.041 |
.083 |
.0 |
.001 |
.007 |
.102 |
.0 |
.011 |
.001 |
.005 |
.0 |
.291 |
.192 |
.255 |
.001 |
.001 |
.015 |
.052 |
.244 |
.0 |
.024 |
-- |
-- |
-- |
-- |
-- |
.052 |
.06 |
.0 |
.0 |
.962 |
.034 |
.017 |
-- |
-- |
.833 |
.001 |
.005 |
.1 |
.012 |
.003 |
-- |
.001 |
.462 |
-- |
.0 |
-- |
-- |
.0 |
.341 |
.02 |
.082 |
.89 |
.017 |
.23 |
.082 |
.956 |
.003 |
.006 |
.002 |
.0 |
.001 |
.026 |
.064 |
.029 |
.201 |
.093 |
.001 |
-- |
-- |
.003 |
.009 |
.129 |
.051 |
.181 |
.011 |
.004 |
.001 |
.012 |
.008 |
.009 |
-- |
-- |
-- |
.048 |
.024 |
.46 |
.015 |
.0 |
.001 |
.994 |
.001 |
.001 |
.02 |
.013 |
.053 |
.019 |
.102 |
.248 |
.02 |
.0 |
-- |
-- |
-- |
-- |
.0 |
-- |
-- |
.112 |
.001 |
.006 |
.559 |
.972 |
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
Gsk3b
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
6 |
G |
T |
T |
A |
G |
T |
G |
12 |
T |
3 |
C |
A |
T |
A |
9 |
A |
4 |
2 |
C |
C |
G |
T |
A |
C |
A |
A |
T |
G |
T |
G |
A |
20 |
G |
T |
G |
A |
A |
T |
A |
A |
A |
A |
C |
G |
22 |
20 |
6 |
A |
G |
G |
A |
C |
5 |
7 |
C |
A |
C |
G |
G |
C |
T |
T |
G |
20 |
2 |
T |
C |
C |
T |
T |
C |
T |
T |
T |
T |
A |
A |
T |
G |
T |
C |
A |
T |
5 |
32 |
37 |
C |
G |
A |
A |
C |
T |
T |
T |
A |
T |
T |
G |
C |
T |
T |
A |
C |
T |
A |
A |
A |
45 |
T |
T |
G |
2 |
T |
C |
T |
A |
A |
32 |
G |
A |
T |
A |
A |
A |
C |
G |
T |
G |
A |
C |
A |
T |
T |
G |
G |
T |
A |
T |
C |
A |
C |
T |
A |
G |
G |
C |
C |
G |
C |
G |
T |
G |
3 |
A |
C |
G |
G |
A |
C |
A |
G |
G |
G |
2 |
C |
2 |
G |
G |
A |
C |
G |
2 |
10 |
G |
A |
56 |
G |
C |
T |
G |
T |
C |
T |
3 |
C |
G |
C |
C |
C |
G |
G |
A |
G |
4 |
G |
7 |
G |
A |
3 |
5 |
T |
G |
A |
G |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
-
|
A
|
2
|
-
|
3
|
T
|
4
|
C
|
-
|
-
|
-
|
T
|
C
|
C
|
T
|
-
|
3
|
-
|
-
|
CT/4
|
T
|
A
|
C
|
2
|
T
|
T
|
T
|
A
|
A
|
2
|
C
|
G
|
-
|
A
|
C
|
A
|
T
|
2
|
-
|
G
|
G
|
C
|
G
|
3
|
A
|
22/-
|
20/-
|
-
|
T
|
A
|
A
|
-
|
T
|
-
|
-
|
13
|
3
|
T
|
A
|
C
|
T
|
3
|
G
|
A
|
-
|
2/-
|
C
|
G
|
4
|
-
|
C
|
T
|
C
|
C
|
-
|
5
|
T
|
T
|
11
|
3
|
C
|
T
|
A/3
|
7
|
5/-
|
32/-
|
37/-
|
G
|
15
|
G
|
T
|
T
|
C
|
-
|
C
|
C
|
C
|
2
|
A
|
T
|
C
|
C
|
T
|
T
|
A
|
G
|
-
|
G
|
-
|
G
|
3
|
17
|
-
|
C
|
A
|
C
|
T
|
T
|
-
|
A
|
T
|
A
|
G
|
G
|
C
|
T
|
A
|
21
|
A
|
G
|
T
|
2
|
C
|
G
|
C
|
A
|
C
|
T
|
C
|
C/2
|
A/-
|
T
|
C
|
G
|
A
|
2
|
C/-
|
T
|
A
|
9/5
|
A
|
T/-
|
A
|
-
|
3
|
2
|
A
|
2
|
G
|
13
|
G
|
A
|
A
|
T
|
-
|
T
|
-
|
C
|
T
|
4
|
T
|
A
|
-
|
-
|
T
|
G
|
-
|
3
|
A
|
10
|
A
|
2
|
T
|
G
|
3/-
|
T
|
T
|
T
|
G
|
T
|
-
|
15
|
2
|
A
|
4/6
|
A
|
-
|
17
|
G
|
-
|
-
|
C
|
A
|
9
|
T
|
G
|
|