|
.001 |
.987 |
.002 |
.002 |
.005 |
.001 |
.001 |
.582 |
.002 |
.011 |
.001 |
.0 |
.0 |
.0 |
.168 |
.189 |
.01 |
.033 |
.001 |
.007 |
.009 |
.029 |
.002 |
.007 |
.001 |
.024 |
.002 |
.006 |
.066 |
.0 |
.01 |
.001 |
.003 |
.023 |
.001 |
.0 |
.001 |
.0 |
1.0 |
.0 |
.0 |
.001 |
-- |
-- |
-- |
-- |
.088 |
.012 |
.366 |
-- |
-- |
-- |
.02 |
.005 |
.705 |
.003 |
.0 |
.068 |
.291 |
.961 |
.059 |
.991 |
.014 |
.001 |
.053 |
.07 |
.0 |
.048 |
.0 |
1.0 |
.685 |
.035 |
.009 |
.002 |
.0 |
.011 |
-- |
-- |
-- |
.033 |
.006 |
.007 |
.013 |
-- |
.439 |
.004 |
.047 |
.017 |
.446 |
.014 |
.804 |
.0 |
.017 |
-- |
-- |
.006 |
.004 |
.01 |
.008 |
.01 |
.002 |
.002 |
.008 |
.194 |
.372 |
.398 |
.446 |
.542 |
.537 |
.497 |
.468 |
.382 |
.697 |
.059 |
.062 |
.506 |
.299 |
.624 |
.86 |
.002 |
.001 |
.005 |
.007 |
.1 |
.002 |
.334 |
.033 |
-- |
-- |
-- |
-- |
.009 |
.0 |
.0 |
.005 |
.008 |
.047 |
.03 |
.001 |
.001 |
.001 |
.006 |
.01 |
.008 |
.06 |
.019 |
.011 |
.0 |
.001 |
.0 |
.0 |
.0 |
.053 |
.002 |
.001 |
.0 |
.0 |
.036 |
.339 |
.005 |
.326 |
.0 |
.812 |
.01 |
.003 |
.0 |
.001 |
.052 |
.012 |
.018 |
-- |
-- |
-- |
.243 |
.017 |
.009 |
.001 |
.0 |
-- |
-- |
.008 |
.0 |
.01 |
.002 |
.036 |
.0 |
.001 |
.003 |
.995 |
.991 |
.539 |
.956 |
.001 |
.0 |
.001 |
.05 |
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
C |
C |
C |
G |
C |
A |
6 |
8 |
G |
T |
C |
T |
T |
C |
A |
A |
T |
A |
C |
A |
C |
T |
T |
A |
T |
C |
G |
T |
T |
T |
G |
T |
A |
A |
A |
G |
A |
C |
C |
C |
C |
C |
A |
2 |
G |
G |
A |
C |
G |
6 |
5 |
C |
T |
2 |
A |
G |
G |
G |
C |
A |
A |
G |
A |
G |
C |
T |
C |
T |
T |
A |
G |
G |
C |
T |
G |
A |
A |
T |
C |
12 |
10 |
C |
A |
T |
T |
G |
G |
C |
G |
C |
8 |
G |
G |
G |
A |
T |
G |
T |
C |
C |
C |
C |
G |
A |
6 |
C |
C |
C |
A |
A |
A |
T |
C |
2 |
C |
T |
T |
C |
G |
T |
A |
A |
C |
A |
C |
14 |
4 |
A |
G |
A |
T |
C |
T |
C |
G |
C |
C |
G |
G |
T |
A |
A |
2 |
G |
4 |
A |
C |
C |
A |
C |
A |
G |
C |
C |
T |
G |
G |
G |
C |
G |
G |
C |
A |
T |
T |
C |
G |
G |
T |
18 |
A |
C |
T |
G |
A |
A |
C |
7 |
G |
A |
A |
C |
C |
G |
2 |
T |
T |
T |
A |
C |
C |
C |
G |
T |
3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
T
|
T
|
A
|
A
|
A
|
C
|
-
|
8/-
|
G/A
|
G
|
C/3
|
C
|
C
|
T
|
G
|
G
|
G
|
A/2
|
T
|
G
|
A
|
G
|
C
|
G
|
C
|
A
|
T
|
C
|
C
|
G
|
C
|
C
|
G
|
G
|
G
|
T
|
G
|
T
|
T
|
G
|
T
|
T
|
G
|
-
|
A
|
A
|
33
|
5
|
A
|
6/-
|
5/-
|
T
|
G
|
-
|
G
|
T
|
A
|
C
|
A
|
G
|
G
|
A
|
G
|
-
|
T
|
A
|
5
|
C
|
C
|
G
|
A
|
A
|
G
|
C
|
A
|
2
|
2
|
A
|
G
|
12/-
|
10/-
|
T
|
G
|
2
|
C
|
A
|
A
|
T
|
A
|
A
|
-
|
C
|
A
|
T
|
G
|
A
|
2
|
C
|
-
|
G
|
-
|
-
|
-
|
T
|
-
|
T
|
G
|
A
|
G
|
G
|
G
|
C
|
T
|
-
|
T
|
2
|
A
|
T
|
A
|
C
|
-
|
T
|
T
|
G
|
T
|
14/-
|
-
|
G
|
-
|
5/7
|
C
|
T
|
G
|
T
|
C
|
T
|
T
|
A
|
-
|
G
|
G
|
A/27
|
2/-
|
3
|
-
|
G
|
T
|
T
|
T
|
T
|
G
|
A
|
T
|
T
|
C
|
4/3
|
A
|
A
|
T
|
A
|
A
|
T
|
G
|
C
|
C
|
T
|
5/3
|
A
|
C
|
-
|
G
|
2
|
C
|
-
|
G
|
G
|
A
|
-
|
T
|
-
|
3
|
G
|
T
|
A
|
2/-
|
T/2
|
T/4
|
C
|
G
|
C/3
|
G
|
T
|
C
|
C
|
-
|
|