|
.044 |
.001 |
-- |
.039 |
.234 |
.032 |
.004 |
-- |
.009 |
.054 |
.046 |
.05 |
.001 |
.041 |
.028 |
.015 |
.045 |
.009 |
.048 |
-- |
.01 |
.017 |
.009 |
.001 |
.006 |
-- |
-- |
.265 |
.001 |
.0 |
.0 |
.005 |
.013 |
.002 |
.0 |
.0 |
.001 |
.0 |
.001 |
.005 |
.004 |
.007 |
.125 |
-- |
.007 |
.0 |
.002 |
.008 |
.115 |
.218 |
.477 |
.694 |
.665 |
.003 |
.004 |
.006 |
.197 |
-- |
.322 |
.014 |
.041 |
.648 |
.641 |
.539 |
.158 |
.032 |
.026 |
.011 |
.009 |
.148 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.998 |
.998 |
.894 |
.0 |
.04 |
.092 |
1.0 |
.993 |
.0 |
.004 |
.004 |
.01 |
.104 |
.076 |
.208 |
.007 |
.003 |
.132 |
.143 |
.161 |
.254 |
.182 |
.198 |
.219 |
.144 |
.184 |
.234 |
.16 |
.018 |
.076 |
.479 |
.085 |
.037 |
.109 |
.037 |
.029 |
.018 |
.002 |
.006 |
.002 |
.004 |
.102 |
.103 |
.052 |
.014 |
.009 |
.208 |
.386 |
.06 |
.027 |
.003 |
.067 |
.026 |
.059 |
.011 |
.43 |
.006 |
-- |
-- |
-- |
.388 |
.037 |
.013 |
.0 |
.0 |
.001 |
.003 |
.0 |
.0 |
.001 |
.002 |
.003 |
.0 |
.0 |
.0 |
.0 |
.022 |
.0 |
.001 |
.0 |
.99 |
.959 |
.001 |
.001 |
.001 |
.002 |
.001 |
.0 |
.0 |
.003 |
.0 |
1.0 |
.519 |
.031 |
.022 |
.006 |
.003 |
.001 |
.002 |
.007 |
.006 |
.557 |
.003 |
.005 |
.004 |
.001 |
.008 |
.006 |
.0 |
.002 |
.022 |
.104 |
.024 |
.001 |
-- |
-- |
.002 |
.021 |
.001 |
.0 |
.0 |
.0 |
-- |
-- |
-- |
-- |
-- |
.342 |
.085 |
.001 |
.026 |
.034 |
.004 |
.007 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.0 |
.0 |
.001 |
.008 |
.0 |
.001 |
.216 |
.026 |
-- |
-- |
-- |
-- |
-- |
.003 |
.016 |
.04 |
.001 |
.001 |
.0 |
.013 |
.0 |
.208 |
.915 |
.001 |
.0 |
.024 |
.726 |
.0 |
.0 |
.004 |
.004 |
.004 |
.063 |
.16 |
.236 |
.075 |
.998 |
.0 |
.012 |
.027 |
.014 |
-- |
.008 |
.001 |
.61 |
.553 |
.021 |
.015 |
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
Trpm2
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
4 |
12 |
4 |
2 |
C |
A |
8 |
T |
A |
G |
C |
C |
2 |
G |
T |
A |
G |
A |
C |
T |
C |
T |
T |
A |
A |
A |
C |
A |
A |
C |
C |
G |
G |
G |
G |
C |
C |
T |
G |
A |
C |
T |
A |
C |
A |
T |
17 |
4 |
2 |
T |
G |
A |
T |
C |
T |
G |
G |
C |
A |
G |
C |
G |
T |
G |
T |
C |
G |
A |
C |
C |
2 |
G |
G |
G |
G |
A |
2 |
A |
A |
A |
C |
T |
C |
G |
T |
T |
T |
C |
T |
A |
C |
T |
A |
T |
G |
G |
T |
T |
A |
2 |
G |
G |
C |
T |
C |
G |
G |
C |
T |
C |
G |
10 |
C |
G |
C |
A |
A |
A |
A |
A |
A |
G |
T |
T |
T |
A |
C |
A |
C |
G |
T |
G |
A |
8 |
G |
G |
A |
T |
G |
A |
C |
G |
G |
G |
C |
G |
A |
A |
A |
G |
A |
A |
A |
C |
T |
T |
T |
G |
A |
T |
G |
A |
C |
T |
C |
T |
A |
G |
T |
T |
G |
C |
C |
C |
T |
T |
A |
C |
A |
2 |
C |
A |
T |
T |
A |
C |
G |
C |
C |
T |
A |
C |
C |
A |
A |
T |
G |
T |
T |
C |
C |
G |
T |
T |
T |
C |
G |
A |
T |
T |
G |
T |
T |
T |
T |
T |
G |
G |
T |
C |
A |
C |
G |
T |
C |
T |
A |
A |
G |
C |
C |
C |
G |
C |
3 |
C |
C |
T |
4 |
G |
C |
C |
C |
G |
A |
A |
T |
G |
10 |
G |
C |
C |
G |
G |
T |
A |
G |
C |
C |
A |
C |
A |
T |
A |
G |
T |
C |
A |
T |
G |
A |
A |
G |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
4/-
|
-
|
-
|
-
|
T
|
G
|
8/-
|
C
|
G
|
3/GT
|
2
|
T
|
-
|
A
|
C
|
G
|
A
|
3
|
T
|
2
|
T
|
C
|
2
|
G
|
-
|
-
|
T
|
G
|
G
|
T
|
C/G
|
G/2
|
G/A
|
G/A
|
G/A
|
C/T
|
C/A
|
T/C
|
G/A
|
G
|
T
|
7
|
G
|
T
|
G
|
C
|
-
|
-
|
-
|
C
|
A
|
G
|
A
|
T
|
C
|
A
|
A
|
-
|
G
|
C
|
T
|
-
|
C
|
A
|
G
|
T
|
A
|
G
|
T
|
T
|
-
|
3
|
C
|
C
|
G/C
|
A/T
|
2/-
|
A/G
|
G
|
3
|
T
|
G
|
G
|
A
|
C
|
C
|
C
|
G
|
G
|
T
|
T
|
G
|
G
|
-
|
A
|
A
|
G
|
2
|
G
|
-
|
G/C
|
C
|
2
|
C
|
T
|
A
|
A
|
T
|
C
|
A
|
A
|
-
|
T
|
T
|
T
|
2
|
G
|
G
|
G
|
A/2
|
AG/G
|
T
|
2
|
C
|
C
|
2
|
T
|
G
|
G
|
T
|
C
|
A
|
G
|
-
|
A
|
G/A
|
G
|
-
|
A
|
G
|
12/T
|
G/A
|
A
|
C
|
T
|
A
|
C
|
T
|
G
|
C
|
G
|
G
|
T
|
T
|
G
|
C
|
G
|
A
|
G
|
C
|
A
|
G
|
G
|
C
|
T
|
C
|
G
|
A
|
C
|
C
|
A
|
T
|
T
|
T
|
C
|
C
|
G
|
G
|
G
|
-
|
T
|
2
|
C
|
G
|
2
|
3
|
A
|
3
|
4
|
G
|
G
|
CT/3
|
A
|
2
|
G
|
C
|
A
|
C
|
G
|
T
|
T
|
C
|
G
|
C
|
C
|
25
|
A
|
G
|
C
|
C
|
A
|
C
|
2
|
2
|
3
|
-
|
T
|
A
|
G
|
T
|
T
|
G
|
A
|
A
|
G
|
C
|
G
|
G
|
A
|
G
|
A
|
6/7
|
A
|
T
|
3/-
|
C/T
|
T
|
-
|
-
|
2
|
A
|
T
|
T
|
A
|
G
|
T
|
G
|
4
|
-
|
A
|
T
|
T
|
A
|
A
|
C
|
G
|
A
|
T
|
A
|
G
|
T
|
G
|
C
|
G
|
T
|
C
|
6
|
2
|
C
|
A
|
G
|
G
|
-
|
T/-
|
|