|
.264 |
-- |
.004 |
-- |
-- |
.019 |
.097 |
.105 |
.092 |
.02 |
.013 |
.006 |
.124 |
.925 |
.453 |
.488 |
.031 |
.81 |
.402 |
.018 |
.021 |
.0 |
.002 |
.094 |
.012 |
.028 |
.317 |
.207 |
.036 |
.117 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.027 |
.006 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.052 |
.315 |
.005 |
.004 |
.006 |
.008 |
.001 |
.481 |
.061 |
.067 |
.003 |
.002 |
.143 |
.001 |
.001 |
.475 |
.001 |
.098 |
.001 |
.121 |
.117 |
.016 |
.002 |
.002 |
.001 |
.003 |
.002 |
.004 |
.0 |
.019 |
.001 |
.0 |
.0 |
.0 |
.0 |
.018 |
.165 |
.087 |
.037 |
.013 |
.019 |
.0 |
.022 |
.006 |
.011 |
.0 |
.004 |
.005 |
.001 |
.024 |
.011 |
.011 |
.0 |
.0 |
.002 |
.001 |
.01 |
.004 |
.043 |
.19 |
.62 |
.012 |
.097 |
.068 |
.087 |
.014 |
.015 |
.03 |
.012 |
.334 |
.031 |
.001 |
-- |
.049 |
.514 |
.817 |
.124 |
-- |
.002 |
.04 |
.072 |
.123 |
.001 |
-- |
.03 |
.209 |
.521 |
.305 |
.033 |
.021 |
.024 |
.001 |
.066 |
.001 |
.004 |
.028 |
.0 |
.035 |
.224 |
.439 |
.436 |
.012 |
-- |
-- |
-- |
.001 |
.001 |
.006 |
.007 |
.022 |
.201 |
.024 |
-- |
-- |
-- |
-- |
.001 |
.226 |
.002 |
1.0 |
.028 |
.173 |
.001 |
.061 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.138 |
.028 |
.0 |
.166 |
.028 |
.023 |
.221 |
.014 |
.047 |
-- |
.065 |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.041 |
.028 |
.13 |
.002 |
.003 |
.219 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.023 |
.006 |
.017 |
.294 |
.005 |
.0 |
.004 |
.02 |
.007 |
.002 |
.001 |
.033 |
.001 |
.001 |
.012 |
.016 |
.001 |
.122 |
.005 |
.004 |
.068 |
.003 |
.033 |
.003 |
.004 |
.022 |
-- |
.012 |
.004 |
.006 |
.001 |
.052 |
.031 |
.183 |
.003 |
.002 |
.263 |
.001 |
.0 |
.007 |
.034 |
.005 |
.0 |
.021 |
.006 |
.009 |
.152 |
.015 |
.012 |
.001 |
.015 |
.0 |
.01 |
.997 |
.741 |
.001 |
.0 |
.006 |
.005 |
.563 |
.608 |
.028 |
.013 |
.012 |
.035 |
.016 |
.089 |
.003 |
.002 |
.015 |
.001 |
.022 |
.002 |
.154 |
.0 |
.03 |
.003 |
.004 |
.0 |
.01 |
.002 |
.0 |
.001 |
.003 |
.001 |
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
Trpc6
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
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--
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--
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--
|
--
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--
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--
|
--
|
--
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--
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|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
G |
T |
A |
C |
C |
C |
G |
G |
C |
T |
T |
9 |
A |
C |
4 |
C |
A |
G |
T |
G |
A |
A |
T |
G |
C |
C |
C |
G |
A |
C |
T |
T |
T |
C |
A |
C |
A |
A |
T |
T |
A |
2 |
G |
A |
A |
2 |
T |
C |
G |
G |
G |
T |
C |
A |
T |
T |
G |
C |
T |
C |
T |
C |
G |
T |
C |
G |
T |
C |
T |
G |
G |
A |
A |
T |
A |
A |
G |
G |
A |
G |
T |
C |
T |
2 |
A |
A |
C |
A |
C |
A |
T |
G |
T |
T |
A |
C |
T |
G |
G |
T |
T |
A |
C |
G |
G |
A |
G |
G |
G |
T |
G |
A |
G |
G |
A |
T |
C |
G |
G |
T |
T |
C |
G |
T |
C |
T |
C |
A |
C |
G |
T |
G |
A |
A |
C |
G |
4 |
A |
C |
A |
G |
T |
A |
T |
10 |
A |
T |
A |
C |
G |
C |
A |
T |
A |
A |
G |
A |
G |
T |
T |
C |
A |
C |
2 |
C |
C |
C |
A |
A |
C |
T |
T |
2 |
T |
A |
C |
T |
T |
T |
T |
C |
9 |
A |
2 |
C |
C |
G |
G |
C |
G |
T |
A |
G |
T |
C |
18 |
14 |
12 |
A |
T |
T |
T |
C |
T |
G |
T |
A |
G |
C |
T |
G |
G |
T |
C |
A |
G |
8 |
G |
C |
2 |
G |
C |
A |
A |
C |
A |
C |
C |
C |
G |
G |
C |
G |
C |
A |
T |
T |
A |
A |
G |
C |
T |
G |
G |
2 |
C |
G |
C |
T |
T |
T |
T |
G |
5 |
T |
G |
C |
G |
A |
A |
C |
A |
A |
C |
A |
T |
T |
A |
G |
T |
T |
2 |
C |
G |
A |
G |
C |
T |
A |
G |
A |
A |
A |
A |
C |
A |
G |
C |
A |
C |
T |
A |
C |
C |
8 |
A |
G |
T |
C |
T |
T |
A |
G |
G |
2 |
G |
T |
T |
A |
G |
T |
A |
T |
T |
G |
T |
T |
T |
G |
C |
A |
T |
C |
A |
A |
G |
G |
A |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
-
|
55
|
C
|
G
|
T
|
T
|
T
|
T
|
5
|
T
|
C
|
G
|
-
|
T
|
T
|
-
|
T
|
T
|
A
|
A
|
A
|
G
|
T
|
C
|
A
|
T
|
-
|
T
|
A
|
G
|
T
|
C
|
C
|
G
|
T
|
C
|
T
|
C
|
G
|
C
|
G
|
-
|
-
|
C
|
G
|
G
|
-
|
-
|
T
|
T
|
C
|
C
|
A
|
A
|
T
|
C
|
C
|
A
|
T
|
-
|
A
|
C
|
G
|
T
|
C
|
T
|
A
|
C
|
T
|
C
|
A
|
G/3
|
2
|
G
|
C
|
3
|
G
|
-
|
-
|
-
|
A
|
-
|
2
|
-
|
-
|
9
|
G
|
A
|
C
|
G
|
G
|
C
|
C
|
C
|
A
|
C
|
T
|
C
|
A
|
C
|
C
|
A
|
G
|
T
|
C
|
A
|
G
|
A
|
C
|
T
|
C
|
A
|
G
|
C
|
A
|
2
|
C
|
T
|
A
|
A
|
A
|
G
|
A
|
A
|
4
|
10
|
C
|
T
|
G
|
T
|
A
|
C
|
A
|
A/T
|
A/G
|
-
|
4
|
-
|
C
|
T
|
G
|
2
|
C
|
G
|
A
|
-
|
G
|
C
|
6
|
T
|
A
|
-
|
G
|
T/6
|
C
|
2
|
C
|
C
|
A
|
2
|
C
|
T
|
13
|
A
|
-
|
G
|
T
|
A
|
G
|
2
|
T
|
-
|
C
|
2/-
|
A
|
G
|
2
|
A
|
5/7
|
T/4
|
T/13
|
T
|
-
|
16
|
-
|
T
|
T
|
A
|
A
|
T
|
T
|
C
|
G
|
A
|
2
|
T
|
-
|
14/-
|
12/-
|
T
|
C
|
C
|
C
|
T
|
A
|
A
|
C
|
G
|
A
|
T
|
5
|
A
|
A
|
C
|
G
|
13
|
A
|
-
|
C
|
2
|
-
|
A
|
A
|
-
|
G
|
G
|
G
|
T
|
C/11
|
G
|
A
|
T
|
T
|
A
|
-
|
G
|
C
|
C
|
C
|
G
|
A
|
A
|
C
|
A
|
A
|
-
|
A
|
A
|
T
|
C
|
C
|
A
|
G
|
-
|
-
|
C
|
T
|
T
|
A
|
G
|
G
|
T
|
C
|
G
|
T
|
G
|
C
|
G
|
G
|
A
|
C
|
-
|
-
|
T
|
A
|
C
|
A
|
T
|
C
|
-
|
A
|
G
|
G
|
G
|
G
|
T
|
G
|
T
|
G
|
G
|
T
|
G
|
T
|
T
|
G
|
-
|
G
|
2
|
G
|
-
|
C
|
C
|
G
|
T
|
G/13
|
-
|
A
|
C
|
C
|
G
|
A
|
-
|
G
|
A
|
G
|
C
|
C
|
C
|
C
|
A
|
T
|
G
|
C
|
T
|
G
|
G
|
C
|
C
|
C
|
G
|
|