|
.0 |
.015 |
.0 |
.998 |
.077 |
.046 |
.829 |
.001 |
.003 |
.001 |
.001 |
-- |
.002 |
.003 |
.005 |
.016 |
.195 |
.009 |
-- |
.001 |
.005 |
.009 |
.118 |
.691 |
.008 |
.006 |
.101 |
.002 |
.007 |
.385 |
.231 |
.117 |
.019 |
.002 |
.008 |
.102 |
.089 |
.23 |
.034 |
1.0 |
.043 |
.015 |
.005 |
.048 |
.022 |
.198 |
.024 |
.049 |
.001 |
.063 |
.001 |
.03 |
.115 |
.012 |
.011 |
.006 |
.012 |
.698 |
.001 |
.0 |
.002 |
.06 |
.001 |
.002 |
-- |
-- |
.706 |
.741 |
.028 |
.001 |
.001 |
.002 |
.018 |
.007 |
.061 |
.006 |
.002 |
-- |
-- |
-- |
.02 |
.009 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.066 |
.004 |
.015 |
.088 |
.002 |
.001 |
.086 |
.011 |
.006 |
.019 |
.138 |
.278 |
.007 |
.017 |
.027 |
.002 |
.0 |
.005 |
.001 |
.0 |
.004 |
.0 |
.001 |
.345 |
.094 |
.004 |
.072 |
.003 |
.365 |
.137 |
.048 |
.133 |
.029 |
.001 |
.028 |
1.0 |
.188 |
.006 |
.248 |
.349 |
.004 |
.037 |
.047 |
.0 |
.014 |
.093 |
.023 |
.01 |
.002 |
.002 |
.024 |
.023 |
.048 |
.002 |
.054 |
.064 |
.022 |
.092 |
.06 |
.169 |
.999 |
.289 |
.009 |
.011 |
.009 |
.002 |
.011 |
.024 |
.017 |
.049 |
.004 |
.002 |
.013 |
.0 |
.007 |
.001 |
.001 |
.017 |
.001 |
.001 |
.004 |
-- |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
.514 |
.051 |
.027 |
.002 |
.251 |
.081 |
.0 |
.003 |
.0 |
.006 |
.001 |
.001 |
.024 |
.0 |
.004 |
.001 |
.001 |
.005 |
.034 |
.032 |
.003 |
.008 |
.004 |
.003 |
.1 |
.748 |
.799 |
.003 |
.001 |
.037 |
.488 |
.089 |
.052 |
.211 |
.1 |
.097 |
.011 |
.003 |
.009 |
.319 |
.659 |
.045 |
.0 |
.005 |
.329 |
.013 |
.013 |
.014 |
.009 |
.002 |
.021 |
.002 |
.001 |
.007 |
.001 |
.0 |
.0 |
.152 |
.11 |
.108 |
.131 |
.133 |
.128 |
.061 |
.03 |
.102 |
.03 |
.066 |
.805 |
.875 |
.87 |
.003 |
.008 |
.256 |
.005 |
.02 |
.004 |
-- |
-- |
-- |
-- |
-- |
.238 |
.016 |
.004 |
.07 |
.234 |
.355 |
.296 |
.006 |
.051 |
.223 |
.224 |
.233 |
.235 |
.062 |
.219 |
.223 |
.092 |
.001 |
.039 |
.068 |
.023 |
-- |
-- |
.285 |
.017 |
.003 |
.451 |
.208 |
.029 |
.044 |
.529 |
.014 |
.011 |
.006 |
.03 |
.081 |
.0 |
.007 |
.007 |
.002 |
.002 |
.075 |
.008 |
.65 |
.765 |
.016 |
.008 |
.02 |
.108 |
.018 |
.002 |
.012 |
.025 |
.009 |
.014 |
.001 |
.007 |
.009 |
.08 |
.169 |
.161 |
.018 |
.02 |
.001 |
-- |
-- |
.034 |
.0 |
.015 |
.0 |
.039 |
.0 |
.03 |
.006 |
.02 |
.016 |
.062 |
.001 |
.018 |
.001 |
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
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--
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--
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--
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--
|
--
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--
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--
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--
|
--
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--
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--
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--
|
--
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--
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--
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--
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--
|
--
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--
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--
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--
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--
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--
|
--
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--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
Tgfbr2
|
|
G |
C |
G |
T |
T |
C |
A |
A |
C |
G |
C |
C |
C |
A |
A |
T |
2 |
A |
G |
A |
A |
A |
T |
C |
A |
C |
G |
T |
T |
T |
16 |
T |
A |
A |
T |
T |
C |
T |
A |
A |
G |
2 |
C |
G |
C |
A |
G |
19 |
G |
C |
T |
T |
G |
C |
T |
C |
G |
T |
T |
A |
T |
G |
A |
A |
13 |
A |
G |
G |
T |
C |
G |
A |
T |
2 |
G |
T |
2 |
G |
T |
C |
T |
C |
T |
A |
G |
A |
C |
4 |
2 |
A |
4 |
T |
G |
G |
G |
T |
C |
T |
A |
G |
C |
G |
T |
C |
T |
G |
C |
A |
A |
T |
C |
C |
A |
G |
C |
T |
T |
T |
T |
A |
C |
C |
A |
T |
G |
G |
11 |
T |
C |
C |
A |
A |
G |
T |
A |
C |
G |
C |
A |
C |
C |
T |
T |
G |
T |
G |
G |
C |
G |
A |
A |
A |
A |
G |
A |
C |
G |
T |
C |
C |
G |
G |
5 |
G |
T |
T |
T |
A |
G |
A |
T |
T |
A |
A |
T |
A |
T |
C |
G |
G |
C |
A |
A |
G |
4 |
T |
C |
T |
A |
G |
C |
T |
G |
T |
A |
C |
A |
10 |
G |
G |
T |
A |
A |
C |
G |
C |
C |
G |
C |
G |
T |
G |
C |
G |
G |
T |
G |
A |
A |
A |
T |
C |
A |
G |
G |
G |
A |
G |
T |
C |
C |
C |
G |
A |
C |
T |
A |
G |
A |
G |
G |
T |
A |
C |
T |
G |
C |
A |
19 |
C |
G |
T |
G |
G |
T |
52 |
14 |
8 |
A |
A |
A |
T |
G |
G |
C |
G |
A |
T |
C |
T |
T |
T |
C |
C |
G |
T |
A |
G |
G |
A |
C |
C |
2 |
G |
2 |
C |
G |
5 |
A |
G |
C |
C |
G |
C |
A |
A |
G |
C |
A |
G |
C |
T |
C |
G |
G |
T |
G |
A |
A |
17 |
A |
A |
A |
A |
T |
G |
T |
T |
G |
A |
G |
C |
T |
T |
G |
A |
T |
C |
T |
A |
C |
T |
T |
G |
G |
T |
G |
A |
A |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
A
|
G/A
|
C
|
A
|
T
|
17
|
A/G
|
T
|
A
|
2
|
T
|
G
|
T
|
-
|
C
|
2/-
|
C
|
3
|
G
|
G
|
G
|
G
|
T
|
G
|
T
|
A
|
C
|
C
|
C
|
-
|
C
|
T
|
G
|
C
|
C
|
T
|
C
|
C
|
G
|
C
|
-
|
A
|
G/A
|
G
|
A/G
|
C
|
-
|
C
|
G
|
G
|
C
|
A
|
3
|
C
|
T
|
A
|
C
|
A
|
G
|
A
|
A
|
C
|
A/G
|
13/-
|
A/G
|
G/3
|
G/3
|
G
|
T
|
A
|
G
|
C
|
-
|
A
|
C
|
2/-
|
2
|
C
|
2
|
C
|
T
|
T/C
|
G
|
C
|
A/3
|
T
|
4/-
|
-
|
G
|
4/-
|
C
|
A
|
C
|
A
|
C
|
T
|
C
|
G
|
A
|
T
|
G/A
|
C
|
G
|
T/C
|
A
|
A
|
G
|
G
|
C
|
T
|
T
|
T
|
A
|
T
|
G
|
3
|
C
|
C
|
G
|
T
|
T
|
G
|
C
|
A
|
C
|
-
|
2
|
C/5
|
C/13
|
-
|
A/G
|
5
|
C
|
G
|
T
|
-
|
A
|
A/G
|
C/T
|
G
|
T/A
|
C
|
C
|
T/2
|
35
|
G/C
|
C/6
|
A
|
-
|
T
|
G
|
-
|
T
|
T
|
A
|
A
|
C
|
A
|
T
|
C
|
A
|
-
|
A
|
C
|
2
|
18
|
G
|
A
|
A/G
|
C
|
T/2
|
G
|
T
|
G
|
C
|
2
|
T
|
5
|
A
|
T
|
G
|
T
|
3
|
4/-
|
C
|
A
|
C
|
C
|
A
|
8
|
A
|
A
|
C
|
7
|
A
|
11
|
10/-
|
T
|
C
|
T/A
|
A/G
|
G
|
T
|
A
|
C/T
|
C/T
|
C
|
T
|
A
|
C
|
A
|
T
|
G/A
|
A
|
T/C
|
T
|
G
|
G
|
G
|
C
|
T
|
2
|
A
|
A
|
G/A
|
G
|
A
|
C
|
T
|
T
|
T
|
A
|
G
|
A
|
T/2
|
G
|
A
|
G
|
A
|
A
|
T/C
|
G
|
3
|
A
|
C
|
C/3
|
A/-
|
19/-
|
T
|
C
|
C
|
A
|
A
|
C
|
-
|
14/-
|
8/-
|
G
|
A/G
|
C
|
C
|
A
|
A
|
T
|
A
|
T
|
-
|
C/T
|
-
|
T/G
|
G
|
T
|
T
|
G/15
|
T/C
|
G
|
A
|
A
|
T
|
A
|
T
|
-
|
A
|
-
|
T
|
A
|
5/-
|
G
|
A
|
G
|
T
|
C
|
T
|
A/5
|
T
|
A
|
T
|
A/2
|
G/A
|
A
|
-
|
T
|
C
|
A
|
T/C
|
C
|
G
|
G
|
-
|
12
|
A/G
|
C
|
G
|
A
|
A
|
C
|
T/2
|
A
|
G
|
A
|
T
|
T/2
|
C
|
A
|
G
|
C
|
T
|
-
|
G
|
T
|
C
|
C
|
A
|
G/6
|
T/2
|
A
|
G
|
G
|
T
|
|