|
.002 |
.866 |
.012 |
.001 |
.341 |
.001 |
.052 |
.004 |
.003 |
.016 |
.005 |
.004 |
.318 |
.181 |
.003 |
.077 |
.001 |
-- |
-- |
.231 |
.645 |
.013 |
.003 |
.303 |
.033 |
.006 |
.01 |
.024 |
.024 |
.001 |
.001 |
.013 |
.133 |
.015 |
.018 |
.011 |
.11 |
.905 |
.018 |
.006 |
.0 |
.0 |
.0 |
.003 |
.002 |
-- |
-- |
-- |
.002 |
.015 |
.012 |
.048 |
.756 |
.013 |
.007 |
.005 |
.018 |
.0 |
.001 |
.004 |
.036 |
.256 |
.12 |
.886 |
.266 |
-- |
.003 |
.359 |
.003 |
.025 |
.013 |
.006 |
.018 |
-- |
-- |
.058 |
.02 |
.036 |
.861 |
.002 |
.001 |
.009 |
.117 |
.06 |
.056 |
.145 |
.002 |
.002 |
.007 |
.232 |
.035 |
.006 |
.194 |
.54 |
.07 |
.002 |
.227 |
.001 |
.005 |
.39 |
.043 |
.002 |
.005 |
.001 |
.017 |
.079 |
.007 |
.012 |
.013 |
.108 |
.125 |
.006 |
.0 |
1.0 |
.023 |
.104 |
.001 |
.018 |
.001 |
.713 |
.001 |
.053 |
.0 |
1.0 |
.006 |
.004 |
.815 |
.034 |
-- |
.023 |
-- |
-- |
.215 |
.045 |
.007 |
.02 |
.045 |
.078 |
.111 |
.042 |
.011 |
.099 |
.09 |
.286 |
.0 |
.002 |
.0 |
.018 |
.001 |
.006 |
.002 |
.798 |
.0 |
.0 |
.0 |
.001 |
.0 |
.001 |
-- |
.008 |
.002 |
.002 |
.0 |
.01 |
.001 |
.116 |
.011 |
.014 |
.014 |
.005 |
.001 |
.011 |
.002 |
.011 |
.022 |
.023 |
.001 |
.067 |
-- |
-- |
-- |
.177 |
.007 |
.003 |
.003 |
.0 |
.0 |
.998 |
.03 |
.008 |
.023 |
.0 |
.012 |
.0 |
.006 |
.002 |
.0 |
.0 |
.058 |
.001 |
.0 |
.001 |
.004 |
.001 |
.0 |
.005 |
.011 |
.063 |
.002 |
.002 |
.001 |
.002 |
.012 |
.0 |
.097 |
.087 |
.062 |
.006 |
.039 |
.993 |
.985 |
.03 |
.981 |
.001 |
.011 |
.34 |
.001 |
.104 |
.002 |
.042 |
.003 |
.037 |
.007 |
.021 |
.001 |
.015 |
.011 |
.011 |
.0 |
.27 |
.0 |
.025 |
.008 |
.07 |
.877 |
.001 |
.0 |
.162 |
.988 |
.653 |
.114 |
.155 |
.0 |
.001 |
.007 |
.738 |
.033 |
.015 |
.002 |
-- |
.001 |
.003 |
.019 |
.002 |
.017 |
.0 |
.003 |
.007 |
.142 |
.048 |
.007 |
.002 |
.015 |
.018 |
.001 |
.494 |
.001 |
.014 |
.011 |
.001 |
.0 |
.001 |
.002 |
.003 |
.0 |
.001 |
.0 |
.401 |
.0 |
.0 |
.002 |
.0 |
.0 |
.002 |
.034 |
.001 |
.015 |
.273 |
.0 |
.009 |
.0 |
.001 |
.0 |
.004 |
.014 |
.069 |
.001 |
.002 |
.998 |
.991 |
.996 |
.903 |
.996 |
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
Scn2a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
A |
T |
A |
T |
G |
C |
G |
C |
A |
A |
T |
T |
T |
C |
A |
A |
G |
C |
T |
T |
G |
A |
C |
A |
T |
A |
C |
T |
C |
C |
A |
A |
G |
C |
C |
A |
T |
G |
G |
T |
C |
T |
C |
T |
G |
C |
A |
C |
G |
A |
G |
G |
2 |
C |
T |
T |
T |
C |
G |
G |
T |
T |
2 |
G |
G |
T |
G |
T |
A |
A |
A |
T |
G |
G |
12 |
A |
2 |
T |
C |
T |
G |
C |
G |
A |
T |
C |
T |
A |
T |
T |
C |
G |
A |
A |
T |
T |
T |
A |
C |
A |
T |
C |
A |
C |
G |
C |
T |
T |
A |
C |
G |
A |
T |
C |
G |
C |
T |
2 |
G |
T |
44 |
T |
A |
C |
A |
T |
C |
T |
T |
T |
G |
A |
T |
T |
T |
C |
C |
C |
C |
C |
C |
A |
T |
T |
C |
G |
C |
T |
T |
A |
T |
C |
T |
C |
A |
C |
G |
T |
A |
T |
C |
C |
C |
T |
A |
5 |
G |
T |
G |
T |
A |
G |
G |
G |
T |
T |
T |
G |
T |
C |
T |
A |
A |
G |
C |
T |
T |
5 |
T |
A |
A |
A |
T |
C |
A |
C |
A |
A |
A |
T |
A |
G |
T |
A |
G |
G |
G |
A |
G |
C |
G |
C |
T |
T |
T |
C |
T |
T |
G |
A |
C |
G |
G |
A |
G |
T |
A |
C |
A |
T |
A |
T |
A |
G |
G |
G |
G |
G |
3 |
C |
A |
7 |
G |
G |
T |
T |
A |
A |
T |
T |
T |
A |
C |
T |
T |
G |
A |
C |
A |
T |
T |
G |
G |
C |
C |
T |
T |
T |
C |
G |
A |
C |
G |
G |
C |
G |
C |
A |
T |
C |
G |
A |
T |
T |
G |
A |
C |
G |
G |
A |
T |
T |
G |
T |
G |
G |
T |
T |
T |
C |
A |
G |
T |
T |
T |
G |
A |
T |
2 |
G |
A |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
A
|
C
|
-
|
C
|
C
|
2
|
T
|
A
|
T
|
G
|
C
|
C
|
C
|
T/C
|
T
|
C
|
A/G
|
G/T
|
T
|
G
|
T/G
|
A
|
-
|
G
|
C
|
C
|
A/G
|
A
|
G
|
T
|
T
|
T
|
A/T
|
A
|
T
|
T
|
C
|
C
|
T
|
T
|
T/-
|
G
|
T/6
|
A
|
-
|
A
|
T
|
T
|
T
|
A
|
G
|
A
|
A
|
-
|
G
|
T/C
|
T/-
|
C
|
T
|
A
|
T
|
9
|
-
|
-
|
T
|
A
|
C
|
G/T
|
3
|
G
|
G
|
G
|
C
|
A
|
A
|
12/-
|
G
|
-
|
C
|
T
|
C
|
C
|
A
|
A
|
2
|
C
|
T
|
C
|
G
|
2
|
C
|
A
|
2
|
T
|
C
|
C
|
G
|
C
|
T
|
T
|
A/T
|
C
|
T
|
A/2
|
G
|
A
|
G
|
2
|
2
|
2
|
T
|
A
|
T
|
C
|
T
|
A
|
T
|
C
|
2/-
|
A
|
G
|
-
|
C
|
G
|
T
|
G
|
C
|
A
|
-
|
C
|
C
|
G/A
|
G
|
G
|
T/A
|
C
|
T
|
T
|
T
|
T
|
T
|
T
|
A/G
|
G
|
C
|
T
|
2
|
T
|
T/C
|
C
|
G
|
G
|
T
|
G
|
T
|
T
|
A
|
T
|
C
|
G
|
T/C
|
C/2
|
T
|
G
|
A
|
A/G
|
-
|
T
|
-
|
T
|
C
|
-
|
A
|
A
|
A
|
G
|
-
|
C
|
A
|
C
|
T
|
-
|
-
|
T
|
A
|
C/2
|
T/3
|
C
|
-
|
T/G
|
C
|
G
|
A/C
|
C
|
C/T
|
G
|
T
|
G
|
G
|
T
|
A
|
G
|
A
|
A
|
G
|
A
|
A
|
A
|
G
|
A
|
T
|
A
|
A
|
C
|
-
|
A
|
T
|
C
|
A
|
G/2
|
A/-
|
T
|
A
|
A
|
G
|
A
|
C
|
G
|
T
|
C
|
-
|
G
|
A
|
G
|
A
|
A
|
A
|
A
|
C
|
-
|
T
|
2
|
-
|
A
|
A
|
T/2
|
2
|
T
|
-
|
A
|
C
|
C
|
G
|
A
|
C
|
5
|
A
|
T
|
C/A
|
G
|
-
|
C
|
A
|
A
|
T
|
T
|
C
|
-
|
C
|
6
|
T
|
T
|
T
|
C
|
T
|
C/T
|
A
|
A
|
G
|
C
|
T
|
T
|
2
|
C
|
T/C
|
G/A
|
G
|
C/2
|
A
|
G/A
|
A/G
|
T/C
|
C
|
T
|
C
|
A
|
A
|
G
|
C
|
C
|
T
|
C
|
G/40
|
-
|
3
|
3
|
A
|
T
|
C
|
2/-
|
A
|
2
|
2
|
|