|
-- |
.008 |
.002 |
.005 |
.005 |
.105 |
.161 |
.027 |
.999 |
.002 |
.011 |
.006 |
.292 |
.189 |
.09 |
.003 |
.199 |
.002 |
.018 |
.109 |
.016 |
.001 |
.031 |
.001 |
.173 |
.914 |
.004 |
.073 |
.119 |
.264 |
.964 |
1.0 |
.343 |
.114 |
.006 |
.047 |
.007 |
.0 |
.004 |
.004 |
.002 |
.0 |
.031 |
.002 |
.002 |
.013 |
.012 |
.388 |
.398 |
.871 |
.074 |
.001 |
.952 |
.794 |
-- |
-- |
-- |
-- |
-- |
.001 |
.016 |
.001 |
.992 |
.101 |
.008 |
.515 |
.001 |
.163 |
.15 |
.057 |
.046 |
.039 |
.001 |
-- |
-- |
-- |
-- |
.135 |
.0 |
.873 |
.901 |
.003 |
.002 |
.018 |
.0 |
.001 |
.0 |
.03 |
.023 |
.004 |
.066 |
.051 |
.002 |
.025 |
.076 |
.23 |
.47 |
.007 |
.001 |
.054 |
.069 |
-- |
-- |
.003 |
.336 |
.001 |
.001 |
.092 |
.079 |
.005 |
.0 |
.001 |
.036 |
.0 |
.02 |
.007 |
.0 |
.008 |
.725 |
-- |
.056 |
.026 |
.021 |
.001 |
.0 |
.023 |
.031 |
.0 |
.003 |
.0 |
.974 |
.04 |
.179 |
.012 |
.019 |
.023 |
.024 |
.0 |
.006 |
.003 |
.019 |
.0 |
.158 |
.342 |
.171 |
.181 |
.041 |
.003 |
.001 |
.001 |
.009 |
.335 |
.036 |
.002 |
.0 |
.003 |
.095 |
.011 |
.002 |
.002 |
.001 |
.0 |
.038 |
.003 |
.037 |
.0 |
.025 |
.025 |
.013 |
.009 |
.006 |
.002 |
.003 |
.979 |
.001 |
.044 |
.0 |
.034 |
.001 |
.001 |
.002 |
.003 |
.011 |
.076 |
.497 |
.017 |
.001 |
.001 |
.001 |
.008 |
.001 |
.007 |
.004 |
.045 |
.002 |
.001 |
.003 |
.0 |
.15 |
.053 |
.019 |
.016 |
.005 |
.816 |
.057 |
.173 |
.014 |
-- |
-- |
-- |
-- |
-- |
-- |
.055 |
.145 |
.009 |
.552 |
.006 |
.002 |
.001 |
.929 |
.983 |
.0 |
.008 |
.062 |
.049 |
.171 |
.0 |
.0 |
.018 |
.014 |
.105 |
.283 |
.395 |
.966 |
.963 |
.742 |
.984 |
.594 |
.004 |
.001 |
.001 |
.023 |
.009 |
.0 |
.589 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.001 |
.056 |
.109 |
.005 |
.034 |
.202 |
.012 |
.021 |
.013 |
.009 |
.0 |
.075 |
.002 |
.094 |
.226 |
.012 |
.005 |
.085 |
.031 |
.004 |
.32 |
-- |
.009 |
.014 |
.012 |
.012 |
.198 |
.02 |
.056 |
.324 |
.015 |
.29 |
.01 |
.009 |
.018 |
.018 |
.059 |
.039 |
.044 |
.006 |
.001 |
.213 |
.002 |
.005 |
.006 |
.004 |
.002 |
.031 |
.002 |
.007 |
.069 |
.008 |
.006 |
.016 |
.54 |
.002 |
.091 |
.026 |
.069 |
.044 |
.796 |
.002 |
.02 |
.001 |
.017 |
.292 |
.02 |
.002 |
.001 |
.073 |
.409 |
.0 |
.003 |
.091 |
.055 |
.017 |
.023 |
.004 |
.005 |
.002 |
.001 |
.013 |
.106 |
.044 |
.0 |
.0 |
.067 |
.001 |
.061 |
.126 |
.002 |
.001 |
.069 |
.051 |
.175 |
.005 |
.001 |
.002 |
-- |
-- |
-- |
-- |
.059 |
.387 |
.005 |
.012 |
.0 |
.0 |
.044 |
.0 |
.0 |
.879 |
.0 |
.007 |
.982 |
.858 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
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--
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--
|
--
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--
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--
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--
|
--
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--
|
--
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--
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--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
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--
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--
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--
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--
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--
|
--
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--
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
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--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
Scn1a
|
|
14 |
A |
G |
T |
T |
T |
C |
A |
2 |
A |
G |
T |
G |
C |
T |
A |
G |
C |
A |
C |
C |
C |
A |
T |
C |
A |
A |
C |
6 |
T |
T |
A |
A |
C |
G |
A |
C |
G |
T |
C |
G |
A |
G |
C |
T |
C |
C |
T |
T |
C |
C |
T |
C |
C |
G |
A |
G |
A |
A |
G |
12 |
C |
C |
C |
C |
G |
C |
20 |
16 |
18 |
16 |
T |
C |
G |
A |
A |
C |
C |
A |
T |
G |
G |
A |
G |
G |
A |
T |
C |
T |
T |
T |
C |
G |
T |
C |
T |
A |
G |
G |
A |
G |
2 |
2 |
G |
C |
A |
C |
A |
A |
T |
A |
A |
A |
C |
T |
C |
T |
6 |
T |
C |
T |
T |
C |
A |
G |
4 |
4 |
A |
C |
T |
A |
T |
T |
G |
T |
G |
G |
T |
T |
T |
A |
A |
G |
A |
3 |
2 |
6 |
6 |
G |
C |
C |
C |
T |
C |
T |
G |
G |
G |
C |
C |
A |
A |
G |
G |
A |
A |
A |
T |
A |
A |
G |
C |
A |
C |
9 |
G |
C |
A |
C |
T |
T |
C |
T |
C |
A |
G |
4 |
A |
T |
2 |
G |
G |
T |
T |
A |
A |
C |
T |
C |
C |
C |
A |
G |
G |
G |
C |
A |
C |
T |
G |
T |
T |
C |
3 |
6 |
G |
A |
G |
C |
A |
A |
G |
A |
A |
A |
C |
G |
T |
C |
T |
C |
A |
G |
T |
A |
2 |
A |
G |
T |
A |
A |
G |
A |
A |
G |
T |
G |
A |
T |
T |
T |
5 |
G |
G |
G |
G |
G |
T |
A |
C |
C |
A |
A |
4 |
2 |
T |
G |
C |
G |
A |
G |
G |
G |
T |
G |
C |
24 |
A |
G |
C |
C |
T |
C |
T |
T |
T |
T |
T |
C |
C |
G |
2 |
T |
G |
T |
T |
T |
G |
T |
C |
A |
T |
C |
G |
T |
G |
12 |
10 |
T |
T |
C |
T |
G |
14 |
12 |
A |
C |
A |
A |
G |
T |
T |
C |
C |
A |
A |
A |
C |
C |
T |
T |
T |
G |
T |
A |
C |
C |
C |
A |
3 |
2 |
T |
T |
T |
A |
C |
G |
G |
A |
A |
G |
T |
T |
G |
12 |
10 |
8 |
T |
A |
G |
C |
T |
A |
C |
G |
G |
G |
A |
T |
A |
G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14/-
|
G
|
A
|
A
|
C
|
-
|
G
|
G
|
-
|
2
|
A
|
C
|
11
|
T
|
C
|
?
|
2
|
T
|
G
|
2
|
T
|
G
|
G
|
C
|
T
|
9
|
G
|
T
|
-
|
2
|
C
|
G
|
2
|
T
|
T
|
C
|
T
|
A
|
-
|
T
|
-
|
G
|
A
|
T
|
C
|
T
|
T
|
A
|
A
|
T
|
T
|
-
|
T
|
12
|
A
|
G
|
A
|
G
|
2
|
-
|
-
|
T
|
T
|
G
|
A
|
T
|
T
|
20/-
|
-
|
18/-
|
16/-
|
C
|
T
|
A
|
G
|
G
|
T
|
T
|
G
|
C
|
A
|
A
|
2
|
A
|
A
|
G
|
C
|
T
|
C
|
C
|
2
|
T
|
A
|
G
|
A
|
G
|
3
|
A
|
A
|
-
|
A
|
-
|
-
|
A
|
15
|
C
|
T
|
T
|
C
|
T/66
|
T
|
2
|
2
|
-
|
C
|
T
|
C
|
-
|
2
|
73
|
2
|
2
|
2
|
G
|
A
|
-
|
-
|
2
|
A
|
C
|
A/3
|
-
|
C
|
A
|
C
|
C
|
A
|
G
|
C
|
C
|
2
|
G
|
A
|
-
|
3/-
|
-
|
-
|
-
|
-
|
G
|
2
|
T
|
-
|
T
|
C
|
14
|
A
|
A
|
G
|
T
|
G
|
G
|
A
|
A
|
C
|
C
|
10
|
T/-
|
-
|
C
|
A
|
T
|
G
|
T
|
-
|
A
|
T
|
G
|
T
|
C
|
C
|
A
|
C
|
T
|
A/3
|
A
|
4/-
|
G
|
G
|
-
|
C
|
-
|
A
|
A
|
G
|
G
|
G
|
C
|
T
|
T
|
T
|
G
|
2
|
A
|
A
|
T
|
5
|
3
|
C
|
A
|
C
|
A
|
A
|
-
|
-
|
A
|
G
|
C
|
T
|
C
|
G
|
C
|
G
|
4
|
2
|
T
|
C
|
C
|
A
|
C
|
T
|
2
|
A
|
C
|
T
|
-
|
G
|
-
|
-
|
G
|
4
|
A
|
T
|
C
|
C
|
C
|
A
|
G
|
-
|
G
|
G
|
-
|
T
|
T
|
T
|
A
|
A
|
-
|
G
|
T
|
T
|
-
|
G
|
4/-
|
2/-
|
C
|
T
|
T
|
A
|
C
|
T
|
3
|
2
|
A
|
A
|
G
|
24/-
|
4
|
4
|
2
|
T
|
10
|
T
|
C
|
C
|
G
|
C
|
C
|
T
|
T
|
A
|
-
|
-
|
A
|
A
|
G
|
6
|
3
|
2
|
A
|
2
|
C
|
G
|
2
|
-
|
T
|
12/-
|
-
|
C
|
3
|
T
|
C
|
6
|
14/-
|
12/-
|
G
|
T
|
G
|
T
|
A
|
A
|
C
|
T
|
T
|
G
|
G
|
G
|
A
|
T
|
A
|
G
|
C
|
A
|
-
|
G
|
T
|
2
|
T
|
G
|
-
|
2/-
|
C
|
-
|
A
|
T
|
G
|
A
|
A
|
G
|
4
|
A
|
2
|
A
|
A
|
12/-
|
10/-
|
8/-
|
C
|
3
|
T
|
T
|
C
|
G
|
T
|
A
|
A
|
2
|
T
|
C
|
G
|
22
|
|