|
.039 |
.083 |
.019 |
.023 |
.154 |
.183 |
.078 |
.039 |
.018 |
.023 |
.01 |
.023 |
.201 |
.011 |
.005 |
.033 |
.004 |
.109 |
.01 |
-- |
-- |
.09 |
.047 |
.053 |
.154 |
.165 |
.003 |
.014 |
-- |
-- |
-- |
.026 |
.005 |
.035 |
.059 |
.108 |
.004 |
.001 |
.006 |
.003 |
.032 |
.581 |
-- |
.065 |
.006 |
.005 |
.001 |
.001 |
.033 |
.157 |
.004 |
.0 |
.778 |
.783 |
.031 |
.111 |
.135 |
.214 |
.0 |
.006 |
.003 |
.003 |
.026 |
-- |
.18 |
.043 |
.233 |
-- |
-- |
-- |
-- |
.033 |
.004 |
.035 |
.995 |
-- |
.006 |
.014 |
.002 |
.002 |
1.0 |
.013 |
-- |
.146 |
.003 |
.024 |
.015 |
.022 |
.001 |
.032 |
.001 |
.503 |
-- |
.093 |
.032 |
.049 |
.25 |
.013 |
.014 |
.309 |
.001 |
.0 |
.008 |
.116 |
.013 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.012 |
.005 |
.03 |
.004 |
.0 |
.01 |
.019 |
.012 |
.053 |
.001 |
.0 |
.029 |
.313 |
.0 |
.002 |
.005 |
.0 |
.09 |
.0 |
.0 |
.0 |
.002 |
.0 |
.657 |
.941 |
.012 |
.062 |
.015 |
.845 |
.996 |
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
C |
C |
C |
3 |
T |
T |
G |
G |
T |
T |
G |
T |
C |
T |
C |
C |
G |
C |
A |
C |
G |
A |
T |
C |
T |
T |
T |
A |
C |
T |
T |
C |
G |
7 |
G |
A |
G |
G |
C |
A |
A |
A |
A |
G |
C |
G |
C |
G |
T |
G |
C |
C |
C |
G |
T |
C |
G |
G |
G |
T |
T |
C |
C |
A |
T |
G |
T |
G |
G |
4 |
4 |
A |
C |
T |
C |
2 |
C |
A |
G |
C |
C |
A |
2 |
A |
C |
C |
G |
C |
T |
G |
7 |
A |
G |
C |
A |
T |
C |
G |
T |
4 |
2 |
T |
C |
A |
C |
C |
A |
C |
G |
C |
A |
A |
C |
T |
G |
G |
G |
G |
A |
A |
C |
C |
7 |
A |
G |
G |
G |
C |
A |
2 |
G |
G |
C |
G |
C |
G |
T |
T |
A |
C |
G |
2 |
C |
C |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
-
|
CT/5
|
T
|
-
|
C
|
-
|
A
|
4/5
|
G
|
C
|
A
|
C
|
T
|
C
|
T
|
-
|
2
|
24
|
G
|
T
|
-
|
G
|
C
|
2
|
G
|
G
|
C
|
22
|
T
|
C
|
C
|
G
|
A
|
-
|
A
|
-
|
A
|
A
|
T
|
G
|
G
|
T
|
G
|
A
|
T
|
A
|
T
|
A
|
C
|
A
|
A
|
T
|
-
|
A
|
G
|
G
|
A
|
A
|
3
|
C
|
G
|
T
|
?
|
G
|
A
|
A
|
A
|
C
|
T
|
-
|
-
|
G
|
4
|
C
|
T
|
-
|
G
|
G
|
A
|
T
|
T
|
G
|
2/-
|
G
|
T
|
G
|
C
|
T
|
C
|
T
|
-
|
G
|
T
|
T
|
5
|
C
|
T
|
A
|
C
|
4/-
|
2/-
|
3
|
T
|
T
|
2
|
T
|
G
|
T
|
A
|
A
|
G
|
T
|
G
|
C
|
A
|
T
|
A
|
A
|
G
|
G
|
T
|
A
|
-
|
G
|
A
|
A
|
A
|
T
|
3
|
-
|
A
|
A
|
T
|
A
|
T
|
T
|
C
|
A
|
G
|
T
|
A
|
-
|
T
|
A
|
G
|
|