|
.0 |
.0 |
.017 |
.133 |
.095 |
.078 |
.052 |
.231 |
.033 |
.0 |
.002 |
.32 |
.069 |
.145 |
.103 |
.101 |
.04 |
.154 |
.183 |
.135 |
.078 |
.111 |
.102 |
.122 |
.098 |
.013 |
.023 |
.002 |
.105 |
.023 |
.201 |
.197 |
.109 |
-- |
-- |
.085 |
.047 |
.053 |
.154 |
.165 |
.003 |
.099 |
.076 |
.014 |
-- |
.026 |
.005 |
.033 |
.003 |
.405 |
.714 |
.026 |
.378 |
.018 |
.014 |
.001 |
.048 |
.032 |
.581 |
1.0 |
.016 |
.001 |
.016 |
.005 |
.001 |
.033 |
.157 |
.004 |
.001 |
.0 |
.0 |
.778 |
.783 |
.001 |
.006 |
.002 |
.031 |
.111 |
.135 |
.852 |
.214 |
.0 |
.006 |
.054 |
.01 |
.003 |
.033 |
.006 |
.003 |
.162 |
.026 |
.18 |
.865 |
.48 |
-- |
-- |
-- |
-- |
.024 |
.995 |
.0 |
-- |
.014 |
.002 |
.036 |
.003 |
.087 |
.005 |
.001 |
.001 |
.0 |
.036 |
.013 |
-- |
-- |
-- |
-- |
-- |
.052 |
.048 |
.029 |
.002 |
.116 |
.9 |
.996 |
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
Ptpn11
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
T |
A |
T |
C |
C |
G |
T |
G |
C |
C |
T |
T |
G |
G |
C |
T |
3 |
T |
G |
T |
G |
C |
6 |
7 |
2 |
T |
C |
C |
G |
T |
T |
G |
A |
C |
G |
A |
T |
C |
T |
T |
G |
C |
T |
T |
T |
C |
T |
G |
C |
C |
T |
C |
G |
C |
G |
T |
A |
A |
C |
T |
G |
C |
C |
C |
G |
T |
G |
A |
C |
G |
C |
C |
C |
G |
G |
G |
T |
C |
13 |
G |
G |
G |
C |
G |
T |
C |
G |
T |
C |
C |
A |
A |
A |
G |
G |
G |
C |
C |
T |
T |
C |
C |
A |
C |
A |
G |
C |
C |
G |
C |
8 |
A |
T |
C |
A |
A |
T |
T |
G |
G |
2 |
G |
C |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
G
|
G
|
-
|
T
|
T
|
A
|
C
|
A
|
T
|
2
|
G
|
4
|
A
|
G/T
|
C/T
|
G
|
-
|
C
|
A
|
-
|
-
|
T
|
6/-
|
7/-
|
2/-
|
G
|
T
|
T
|
G/A
|
C
|
T/C
|
2
|
G
|
T
|
T
|
G
|
C
|
2
|
G
|
G
|
A
|
T
|
T/C
|
C
|
T/C
|
G
|
T/C
|
G/A
|
T
|
T
|
T/C
|
T
|
A
|
T
|
A
|
C
|
G
|
G
|
T
|
C
|
A
|
-
|
T
|
T
|
A
|
C
|
A
|
G
|
A
|
T
|
T
|
-
|
T
|
A
|
A
|
A
|
T/G
|
G
|
-
|
A
|
A
|
3
|
T
|
A
|
C
|
-
|
A
|
G
|
T
|
C/T
|
G
|
G
|
T
|
C
|
A
|
T
|
A
|
C/3
|
C
|
C
|
T
|
G
|
G
|
T
|
G
|
A
|
T
|
T
|
G/T
|
T
|
-
|
T
|
C
|
T
|
G
|
G
|
C
|
T/C
|
T
|
G/A
|
2/-
|
A
|
C/T
|
G
|
|