|
.0 |
.0 |
.009 |
.0 |
.008 |
.001 |
.0 |
.0 |
.0 |
.0 |
.005 |
.0 |
.001 |
.07 |
.0 |
.002 |
.0 |
.0 |
.359 |
.328 |
.145 |
.252 |
.087 |
.0 |
.002 |
.001 |
.004 |
.001 |
.0 |
.0 |
.008 |
.017 |
.0 |
.02 |
.001 |
-- |
-- |
.0 |
.02 |
.0 |
.001 |
.0 |
.0 |
.004 |
.0 |
.996 |
.0 |
.0 |
-- |
.002 |
.0 |
.0 |
.0 |
.0 |
.941 |
.0 |
.001 |
.002 |
.0 |
-- |
.475 |
.079 |
.008 |
.02 |
.112 |
.002 |
.004 |
.0 |
.045 |
.0 |
.0 |
.007 |
.006 |
.007 |
.0 |
.007 |
.001 |
.0 |
.0 |
.03 |
.0 |
.009 |
.002 |
.003 |
.026 |
.004 |
.002 |
.995 |
.285 |
.011 |
.008 |
.001 |
.012 |
.003 |
.003 |
.156 |
.003 |
.0 |
.0 |
-- |
-- |
.001 |
-- |
-- |
-- |
.873 |
.104 |
-- |
.0 |
.002 |
.01 |
.002 |
.0 |
.0 |
.015 |
.001 |
.008 |
-- |
-- |
.005 |
.822 |
.0 |
.001 |
.0 |
.006 |
1.0 |
.857 |
.904 |
.969 |
.0 |
.001 |
.0 |
.0 |
.001 |
.0 |
.996 |
.001 |
.002 |
.039 |
.059 |
.01 |
.026 |
.001 |
.0 |
-- |
.0 |
.0 |
.0 |
.0 |
.134 |
.624 |
.606 |
.015 |
.0 |
.0 |
.011 |
.0 |
.0 |
.003 |
.002 |
.0 |
.004 |
.0 |
.003 |
.019 |
.007 |
.0 |
.0 |
.004 |
.0 |
.025 |
.012 |
.069 |
.96 |
.055 |
.002 |
.002 |
.0 |
.0 |
.002 |
.0 |
.001 |
.0 |
.005 |
.0 |
.006 |
.011 |
.002 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.018 |
.006 |
.002 |
.0 |
.0 |
.0 |
.0 |
.01 |
.001 |
.006 |
.001 |
.001 |
.003 |
.001 |
.002 |
.001 |
.001 |
.003 |
.0 |
.001 |
.002 |
.0 |
.005 |
.093 |
.648 |
.001 |
.0 |
.004 |
.001 |
.006 |
.001 |
.001 |
.001 |
.036 |
.022 |
.001 |
.001 |
.013 |
-- |
-- |
.007 |
.0 |
.0 |
.0 |
.0 |
.0 |
.006 |
.004 |
.039 |
.003 |
.003 |
.001 |
-- |
-- |
-- |
-- |
.001 |
.92 |
.0 |
.002 |
.003 |
.004 |
.985 |
.002 |
.487 |
.005 |
.164 |
.002 |
.002 |
.006 |
-- |
-- |
-- |
-- |
.003 |
.0 |
.001 |
-- |
-- |
-- |
-- |
.0 |
.001 |
.003 |
.0 |
.002 |
.0 |
.101 |
.004 |
.002 |
.001 |
.0 |
.0 |
.005 |
.001 |
.0 |
.009 |
.007 |
.007 |
.0 |
.0 |
.0 |
.005 |
.004 |
.0 |
.0 |
.022 |
.311 |
.001 |
.001 |
.002 |
.099 |
.001 |
.0 |
.01 |
.0 |
.003 |
.001 |
.0 |
.023 |
.0 |
.001 |
.0 |
.001 |
.002 |
.0 |
.005 |
.0 |
.0 |
.0 |
.002 |
.001 |
.0 |
.0 |
.002 |
.0 |
.001 |
.025 |
.006 |
.001 |
.002 |
.002 |
.0 |
.014 |
-- |
.008 |
.007 |
.0 |
.0 |
-- |
-- |
-- |
-- |
.0 |
.015 |
.0 |
.0 |
.0 |
.0 |
.007 |
.334 |
.002 |
.001 |
.003 |
.0 |
.0 |
-- |
-- |
-- |
-- |
.003 |
.0 |
.001 |
-- |
.0 |
.004 |
.001 |
.0 |
.0 |
.002 |
.0 |
.0 |
.001 |
.011 |
.003 |
.0 |
.0 |
.006 |
.002 |
.001 |
.004 |
.014 |
.004 |
.002 |
.073 |
.299 |
.0 |
.001 |
.133 |
.237 |
.002 |
.001 |
.002 |
.001 |
.004 |
.121 |
.023 |
.011 |
.001 |
.001 |
.005 |
.003 |
.006 |
.006 |
.003 |
.009 |
.01 |
-- |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.0 |
.0 |
.003 |
.003 |
.138 |
.003 |
.003 |
.005 |
.005 |
.006 |
.001 |
.089 |
.083 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
.0 |
.0 |
.0 |
.0 |
.028 |
.0 |
.001 |
.012 |
.007 |
.001 |
.0 |
.071 |
.0 |
.003 |
.0 |
.006 |
.011 |
.003 |
.0 |
-- |
-- |
.004 |
.0 |
.115 |
.003 |
.012 |
.802 |
.791 |
.008 |
-- |
-- |
-- |
-- |
-- |
-- |
1.0 |
1.0 |
1.0 |
.981 |
.985 |
.998 |
1.0 |
.001 |
.0 |
.0 |
.0 |
.0 |
.001 |
.002 |
.0 |
.0 |
.0 |
.524 |
.007 |
.491 |
.011 |
.002 |
.002 |
.026 |
.018 |
.001 |
.04 |
.002 |
.007 |
.004 |
.22 |
.002 |
.0 |
1.0 |
.0 |
.0 |
.0 |
.0 |
.0 |
.002 |
.034 |
.02 |
.073 |
.001 |
.037 |
.0 |
.013 |
.011 |
.0 |
.006 |
.999 |
.992 |
.569 |
.004 |
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
Plcb4
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
T |
G |
C |
A |
A |
T |
C |
C |
C |
C |
A |
G |
G |
A |
A |
A |
G |
C |
C |
C |
C |
C |
C |
G |
G |
C |
A |
G |
G |
A |
C |
C |
A |
C |
G |
C |
T |
A |
T |
G |
A |
C |
C |
T |
G |
A |
T |
C |
C |
G |
A |
A |
C |
T |
C |
C |
C |
G |
G |
C |
A |
T |
C |
T |
T |
A |
T |
A |
C |
G |
A |
G |
C |
T |
C |
C |
T |
A |
C |
A |
C |
A |
G |
C |
C |
G |
A |
A |
A |
A |
A |
A |
C |
G |
T |
G |
C |
C |
C |
A |
C |
C |
A |
T |
T |
C |
G |
A |
G |
A |
A |
T |
G |
G |
A |
G |
G |
C |
A |
G |
G |
A |
C |
C |
C |
C |
T |
T |
C |
A |
C |
T |
T |
C |
G |
C |
G |
T |
T |
G |
A |
T |
G |
G |
A |
A |
C |
C |
A |
G |
A |
T |
T |
G |
T |
G |
T |
A |
C |
G |
A |
A |
A |
T |
A |
T |
G |
T |
A |
C |
C |
A |
T |
T |
A |
C |
C |
A |
C |
A |
T |
T |
C |
A |
T |
G |
C |
C |
T |
T |
C |
A |
C |
C |
C |
T |
C |
C |
G |
A |
T |
G |
T |
G |
A |
A |
C |
A |
G |
A |
G |
A |
T |
C |
G |
G |
C |
T |
C |
T |
A |
T |
A |
C |
T |
A |
T |
G |
C |
T |
G |
C |
A |
G |
T |
C |
T |
T |
C |
C |
G |
A |
C |
C |
T |
A |
G |
A |
G |
G |
C |
C |
C |
T |
A |
T |
A |
C |
A |
T |
T |
G |
T |
T |
A |
A |
A |
C |
T |
G |
C |
T |
C |
T |
G |
A |
C |
T |
G |
T |
C |
A |
G |
C |
A |
T |
C |
T |
T |
G |
A |
A |
G |
G |
T |
G |
G |
A |
G |
C |
A |
G |
C |
C |
T |
G |
C |
G |
T |
C |
G |
T |
G |
A |
T |
G |
C |
G |
A |
G |
T |
A |
T |
A |
G |
A |
T |
A |
G |
T |
A |
G |
A |
C |
G |
T |
T |
T |
T |
G |
A |
T |
C |
A |
A |
A |
T |
C |
G |
G |
T |
T |
T |
C |
T |
C |
T |
C |
A |
T |
G |
C |
G |
T |
C |
A |
T |
A |
G |
T |
T |
C |
T |
G |
A |
C |
G |
A |
C |
A |
G |
T |
T |
T |
A |
T |
T |
A |
G |
C |
C |
G |
C |
T |
C |
G |
C |
G |
A |
T |
C |
C |
T |
T |
G |
A |
T |
G |
G |
G |
G |
G |
A |
T |
T |
C |
G |
A |
G |
C |
A |
A |
T |
G |
A |
C |
T |
G |
T |
T |
A |
A |
G |
G |
A |
G |
G |
T |
T |
A |
G |
C |
T |
A |
A |
C |
C |
T |
A |
A |
C |
A |
A |
C |
T |
C |
G |
A |
T |
G |
C |
A |
G |
G |
C |
C |
T |
A |
C |
A |
C |
G |
T |
C |
A |
A |
C |
C |
C |
C |
C |
T |
T |
T |
C |
C |
C |
G |
G |
C |
T |
G |
A |
T |
A |
T |
G |
G |
C |
A |
A |
T |
T |
C |
A |
T |
A |
A |
G |
G |
G |
A |
A |
G |
T |
T |
A |
C |
A |
G |
T |
T |
G |
A |
A |
G |
C |
G |
A |
C |
A |
T |
A |
G |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
A
|
A
|
T
|
G
|
T
|
A
|
T
|
T
|
T
|
T
|
G
|
A
|
A
|
G
|
C
|
G
|
A
|
T
|
T
|
G
|
G
|
G
|
T
|
A
|
A
|
T
|
G
|
T
|
A
|
C
|
T
|
T
|
G
|
G
|
A
|
T
|
C
|
C
|
C
|
T
|
T
|
T
|
G
|
C
|
A
|
C
|
T/C
|
T
|
T
|
C
|
G
|
A/G
|
A
|
C
|
T
|
T
|
T
|
C
|
C
|
T
|
G
|
C
|
T
|
C
|
C
|
G
|
C
|
G
|
T
|
T
|
T
|
A
|
T
|
C
|
T
|
T
|
C
|
T
|
T
|
G
|
T
|
G
|
A
|
T
|
T
|
C
|
T
|
G
|
A/G
|
A/G
|
G
|
C
|
T
|
C
|
C
|
A
|
T
|
T
|
T
|
G
|
G
|
C/T
|
T
|
G
|
A
|
T
|
A
|
G
|
A
|
G
|
G
|
C
|
A
|
A
|
T
|
A
|
G/A
|
C/T
|
A/G
|
A
|
A
|
G
|
A
|
T
|
A
|
A
|
G
|
C
|
C/G
|
G
|
T
|
T/G
|
A
|
T
|
G/A
|
T
|
A
|
G
|
C
|
A
|
G
|
C
|
A
|
G/A
|
A/G
|
T
|
T
|
T
|
G
|
A
|
G
|
G
|
C
|
A
|
C
|
A
|
C
|
T
|
A
|
A
|
G
|
G
|
G
|
C
|
G
|
C
|
A
|
C
|
G
|
T
|
T
|
G
|
G
|
C
|
G
|
T
|
T
|
C
|
T
|
G
|
C
|
G
|
A
|
G
|
G
|
A
|
T
|
T
|
C
|
C
|
A
|
G
|
G
|
T
|
T
|
C
|
G
|
C/G
|
A
|
G
|
C
|
A
|
C
|
A
|
G
|
G
|
A
|
G
|
A
|
T
|
A
|
C
|
C
|
T
|
A
|
A
|
T
|
C
|
T
|
C
|
G
|
G
|
T
|
T
|
C
|
T
|
C
|
A
|
T
|
C
|
A
|
G
|
G
|
A
|
C
|
A
|
C
|
C
|
T
|
C/T
|
A
|
G
|
T
|
A
|
C
|
C
|
A
|
A/C
|
G/C
|
G/C
|
C/G
|
T
|
A
|
A
|
G
|
G
|
T
|
T
|
G
|
C
|
C
|
G/A
|
C
|
C
|
G
|
A/C
|
A/C
|
C/T
|
C
|
A
|
A
|
C
|
T
|
G
|
C
|
G
|
T
|
C
|
A
|
C
|
T
|
G
|
A
|
T
|
G
|
C
|
T
|
C
|
C
|
A
|
C
|
C
|
A
|
T
|
G
|
T
|
A
|
G
|
A
|
G
|
G
|
T
|
A
|
A
|
C
|
A
|
G
|
A
|
A
|
T
|
A
|
C
|
A
|
C
|
C
|
T
|
T
|
A
|
C
|
T
|
G
|
G
|
A
|
G
|
T
|
G
|
C
|
T
|
C
|
A
|
G
|
A
|
G
|
T
|
A
|
C
|
C
|
G
|
C
|
A
|
C
|
G
|
T
|
G
|
G
|
G
|
C
|
A
|
T
|
A
|
C
|
C
|
C
|
T
|
G
|
T
|
A
|
T
|
C
|
C
|
G/A
|
C/G
|
G/A
|
T/C
|
C/T
|
A/G
|
C
|
G
|
G/C
|
T/G
|
C
|
T
|
G
|
A
|
C
|
T
|
C
|
G
|
A
|
C
|
A
|
C
|
T/C
|
C
|
T
|
C
|
C
|
G
|
T
|
G
|
T
|
A
|
T
|
C
|
T
|
A
|
A
|
T
|
G
|
C
|
T
|
T
|
G
|
C
|
A
|
T
|
C
|
G/C
|
G/C
|
G/C
|
G/C
|
G/C
|
C
|
C
|
C
|
T
|
A
|
G
|
C
|
A
|
T
|
G
|
C
|
A
|
G
|
A
|
C
|
A
|
C
|
C
|
T
|
G
|
A
|
C
|
G
|
A
|
A
|
G
|
A
|
G
|
A
|
T
|
C
|
G
|
G
|
T
|
T
|
C
|
T
|
G
|
T
|
G
|
G
|
A
|
C
|
T
|
C
|
G
|
C
|
A
|
G
|
G
|
A
|
A
|
T
|
A
|
G
|
G
|
T
|
C
|
T
|
A
|
A
|
T
|
G
|
T
|
A
|
A
|
T
|
T
|
T
|
T/C
|
T/C
|
T/C
|
T
|
T
|
T
|
G/C
|
A
|
T
|
C
|
A
|
G
|
C
|
G
|
C
|
C
|
A
|
T
|
G
|
G
|
G
|
A
|
T
|
C
|
C
|
C
|
G
|
C
|
A
|
C
|
G
|
C
|
C
|
C
|
C
|
G
|
T
|
G
|
A
|
C
|
C
|
C
|
C
|
G
|
A
|
A
|
A
|
T
|
T
|
G
|
C
|
G
|
T
|
C
|
|