|
.802 |
.93 |
.01 |
.004 |
.001 |
.011 |
.0 |
.04 |
.402 |
.176 |
.01 |
.0 |
.0 |
.002 |
.034 |
.839 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.967 |
.243 |
-- |
.0 |
.001 |
.026 |
.005 |
.009 |
.001 |
.015 |
.031 |
.089 |
.113 |
.0 |
.003 |
.001 |
.004 |
.29 |
.003 |
.011 |
.009 |
.011 |
.004 |
.002 |
.0 |
.213 |
-- |
-- |
.009 |
1.0 |
.999 |
1.0 |
.078 |
.031 |
.019 |
.001 |
.001 |
.001 |
.002 |
.014 |
.001 |
.0 |
.001 |
.0 |
.038 |
.709 |
.002 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.002 |
.027 |
.086 |
.008 |
.0 |
.04 |
.02 |
.003 |
.16 |
.31 |
.005 |
.001 |
.0 |
.261 |
.001 |
.001 |
.003 |
.102 |
.001 |
.529 |
.001 |
.032 |
.074 |
.034 |
.225 |
.025 |
.0 |
.032 |
.005 |
.002 |
.036 |
.024 |
.218 |
.007 |
.947 |
.039 |
.0 |
.013 |
.0 |
.002 |
.003 |
-- |
-- |
-- |
.009 |
.012 |
.203 |
.15 |
.022 |
.092 |
.023 |
-- |
.019 |
.0 |
.01 |
.023 |
.001 |
.382 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.096 |
.0 |
.003 |
.016 |
.079 |
.151 |
.034 |
.032 |
.016 |
.005 |
.001 |
.004 |
.013 |
.283 |
.001 |
.239 |
.273 |
.002 |
.098 |
.02 |
.023 |
.001 |
.002 |
.461 |
.136 |
.001 |
.147 |
.015 |
.0 |
.869 |
.888 |
.001 |
.022 |
.062 |
.002 |
.001 |
.0 |
.994 |
.0 |
.0 |
.011 |
.013 |
.052 |
.033 |
.001 |
.0 |
.046 |
.011 |
.0 |
.0 |
.0 |
.001 |
.0 |
.001 |
.0 |
.0 |
.001 |
.515 |
.0 |
.0 |
.407 |
-- |
-- |
.001 |
.012 |
.053 |
.071 |
.077 |
.079 |
.031 |
.0 |
.003 |
.115 |
.016 |
.004 |
.006 |
.01 |
.618 |
.54 |
.543 |
.161 |
.003 |
.025 |
.002 |
.029 |
.229 |
.0 |
.027 |
.0 |
.001 |
.0 |
.001 |
.004 |
.033 |
.272 |
.157 |
.194 |
.332 |
.008 |
.023 |
.508 |
.062 |
.034 |
.125 |
.059 |
.014 |
.34 |
.004 |
.012 |
.002 |
-- |
.007 |
.046 |
.011 |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.037 |
.051 |
.035 |
.022 |
.001 |
.026 |
.004 |
.004 |
.0 |
.029 |
.107 |
.178 |
.265 |
.007 |
.005 |
.036 |
.12 |
.072 |
.519 |
.005 |
.016 |
.001 |
.328 |
.29 |
.0 |
.001 |
-- |
-- |
.217 |
-- |
-- |
.12 |
.645 |
.032 |
.025 |
-- |
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
Pcsk2
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
Wbp4-ps1
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
T |
G |
T |
C |
C |
T |
G |
A |
A |
G |
T |
A |
G |
G |
A |
2 |
3 |
A |
A |
T |
G |
T |
G |
T |
G |
T |
G |
C |
A |
A |
G |
A |
G |
C |
G |
T |
T |
T |
4 |
C |
G |
A |
A |
6 |
C |
C |
C |
G |
G |
A |
G |
A |
103 |
A |
G |
A |
A |
A |
A |
A |
C |
T |
A |
A |
C |
G |
G |
G |
A |
A |
G |
G |
A |
A |
C |
C |
A |
A |
G |
A |
C |
T |
G |
115 |
G |
T |
T |
C |
T |
A |
4 |
G |
C |
G |
A |
A |
A |
G |
G |
T |
T |
C |
C |
A |
T |
G |
G |
T |
C |
A |
A |
G |
8 |
C |
C |
C |
G |
T |
C |
G |
G |
C |
G |
A |
C |
T |
A |
G |
G |
C |
T |
A |
G |
A |
A |
T |
A |
G |
T |
G |
C |
G |
T |
2 |
6 |
C |
G |
G |
T |
G |
C |
G |
A |
T |
G |
T |
C |
T |
A |
T |
T |
G |
C |
C |
C |
2 |
A |
12 |
10 |
A |
C |
A |
2 |
A |
T |
8 |
4 |
A |
G |
C |
C |
C |
T |
G |
C |
C |
G |
A |
T |
G |
G |
G |
T |
G |
A |
G |
G |
G |
A |
C |
G |
C |
A |
G |
T |
A |
C |
T |
T |
G |
C |
C |
3 |
2 |
A |
14 |
A |
A |
G |
C |
G |
C |
A |
2 |
C |
3 |
G |
A |
2 |
G |
G |
4 |
4 |
C |
4 |
A |
G |
T |
T |
C |
2 |
4 |
G |
A |
A |
C |
3 |
T |
6 |
T |
A |
A |
C |
2 |
A |
T |
G |
A |
G |
C |
8 |
A |
G |
C |
C |
G |
C |
G |
A |
A |
G |
C |
G |
2 |
2 |
A |
T |
3 |
A |
A |
T |
G |
G |
T |
G |
C |
A |
22 |
20 |
A |
G |
A |
G |
A |
T |
A |
G |
T |
T |
G |
T |
G |
T |
A |
C |
4 |
2 |
2 |
G |
3 |
2 |
A |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
-
|
A
|
C
|
G
|
G
|
C
|
A
|
-
|
C
|
A
|
C
|
2
|
C
|
C
|
-
|
-
|
-
|
G
|
G
|
3
|
A
|
G
|
T
|
C
|
A
|
A
|
T
|
T
|
5
|
T
|
A
|
C
|
A
|
T
|
T
|
C
|
C
|
C
|
4/-
|
A
|
A
|
G
|
C
|
-
|
T
|
T
|
2
|
2
|
2
|
T
|
A
|
G
|
-
|
C
|
-
|
2
|
C
|
G
|
2
|
G
|
T
|
C
|
2
|
C
|
G
|
A
|
A
|
A
|
G
|
G
|
T
|
A
|
G
|
G
|
A
|
G
|
C
|
C
|
C
|
A/2
|
T
|
A
|
A
|
-
|
A
|
C
|
C
|
T
|
C
|
T
|
-
|
A
|
T
|
A
|
2
|
4
|
9
|
5
|
2
|
G
|
C
|
A
|
T
|
G
|
A
|
3
|
T
|
C
|
G
|
G
|
G
|
A
|
-
|
4
|
G
|
T
|
T
|
C
|
G
|
A
|
A
|
13
|
2
|
-
|
T
|
C
|
C
|
A
|
A
|
T
|
5
|
G
|
A
|
T
|
-
|
A
|
G
|
A
|
C
|
A
|
-
|
A
|
89
|
2/-
|
6/-
|
G
|
A
|
2
|
G
|
A
|
A
|
A
|
T
|
2
|
2
|
-
|
-
|
-
|
4
|
-
|
3
|
T
|
T
|
T
|
13
|
2/-
|
A/-
|
12/-
|
10/-
|
-
|
T
|
A/T
|
-
|
T
|
C
|
8/-
|
4/-
|
G
|
A
|
15
|
2
|
T
|
A
|
A
|
T
|
T
|
A
|
T
|
-
|
T
|
C
|
C
|
A
|
C
|
C
|
A
|
C
|
C
|
C
|
A
|
C
|
T
|
T
|
A
|
T/2
|
C
|
T
|
T/C
|
T/C
|
3
|
3
|
T
|
3/-
|
2/-
|
A/-
|
-
|
G
|
C
|
T
|
T
|
T
|
T
|
G
|
-
|
C/-
|
3/-
|
-
|
C
|
-
|
A
|
-
|
-
|
-
|
C/A
|
-
|
G
|
A
|
2
|
C
|
T
|
2/-
|
4/-
|
4
|
G
|
G
|
T
|
-
|
A
|
-
|
C
|
G
|
G
|
2
|
-
|
5/7
|
C
|
5
|
G
|
A
|
A
|
-
|
G
|
A
|
T
|
3
|
-
|
-
|
-
|
-
|
G
|
A
|
-
|
T
|
2/-
|
2/-
|
C
|
-
|
-
|
G
|
G
|
C
|
A
|
A
|
C
|
A
|
6
|
T
|
22/-
|
20/-
|
2
|
A
|
3
|
25
|
G
|
-
|
9/7
|
A
|
C
|
C
|
-
|
30
|
G/2
|
T/-
|
A/-
|
A
|
-
|
2/-
|
2/-
|
26
|
-
|
2/-
|
A/-
|
C/5
|
|