|
.002 |
.002 |
.001 |
.001 |
.318 |
.262 |
.003 |
.003 |
.002 |
.011 |
.001 |
.001 |
.0 |
.0 |
.168 |
.189 |
.01 |
.022 |
.033 |
.026 |
.001 |
.007 |
.009 |
.029 |
.002 |
.007 |
.001 |
.024 |
.002 |
.006 |
.066 |
.0 |
.01 |
.001 |
.003 |
.0 |
.023 |
.001 |
.0 |
.0 |
.0 |
.0 |
.001 |
-- |
-- |
-- |
.088 |
.019 |
.246 |
-- |
.019 |
.003 |
.005 |
.705 |
.003 |
.0 |
.0 |
.002 |
.068 |
.291 |
.961 |
.059 |
.991 |
.014 |
.001 |
.053 |
.0 |
.055 |
1.0 |
.0 |
-- |
-- |
-- |
.006 |
.14 |
.061 |
.439 |
.134 |
.007 |
.004 |
.736 |
.008 |
.006 |
.0 |
.067 |
.017 |
-- |
-- |
-- |
.006 |
.006 |
.002 |
.003 |
.03 |
.022 |
.048 |
.106 |
.011 |
.006 |
.006 |
.015 |
.03 |
.044 |
.007 |
.003 |
.003 |
.025 |
.006 |
.003 |
.004 |
.043 |
.002 |
.017 |
.077 |
.093 |
.089 |
.026 |
.021 |
.014 |
.012 |
.005 |
.002 |
.006 |
.003 |
.001 |
.01 |
.002 |
.002 |
.008 |
.194 |
.008 |
.506 |
.299 |
.624 |
.86 |
.446 |
.002 |
.001 |
.005 |
.007 |
.1 |
.002 |
.334 |
-- |
-- |
-- |
-- |
.009 |
.008 |
.0 |
.005 |
.008 |
.047 |
.03 |
.001 |
.001 |
.001 |
.006 |
.06 |
.06 |
.019 |
.011 |
.0 |
.001 |
.0 |
.0 |
.0 |
.053 |
.0 |
.002 |
.001 |
.0 |
.0 |
.036 |
.005 |
.326 |
.0 |
.0 |
.812 |
.01 |
.003 |
.0 |
.001 |
.071 |
.012 |
.018 |
-- |
-- |
-- |
.243 |
.017 |
.009 |
.001 |
.0 |
-- |
.008 |
.049 |
.01 |
.001 |
.002 |
.036 |
.002 |
.0 |
.995 |
.0 |
.001 |
.054 |
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
Glp1r
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
C |
C |
C |
A |
18 |
16 |
A |
T |
8 |
G |
T |
6 |
T |
T |
C |
A |
A |
C |
T |
C |
A |
C |
A |
C |
T |
T |
A |
T |
C |
G |
T |
T |
T |
G |
T |
G |
A |
A |
A |
A |
C |
C |
C |
C |
A |
G |
G |
C |
G |
G |
4 |
C |
T |
2 |
A |
C |
G |
T |
G |
G |
C |
A |
A |
G |
A |
G |
T |
2 |
T |
T |
A |
A |
T |
G |
G |
G |
T |
T |
G |
T |
A |
G |
G |
8 |
T |
G |
G |
G |
C |
A |
A |
A |
T |
C |
T |
A |
T |
C |
G |
T |
C |
A |
T |
C |
A |
A |
G |
A |
A |
T |
A |
T |
A |
A |
T |
T |
T |
C |
T |
T |
T |
C |
G |
G |
T |
C |
C |
C |
C |
G |
A |
C |
T |
T |
C |
G |
G |
T |
A |
A |
C |
A |
C |
4 |
A |
G |
A |
T |
A |
T |
C |
G |
C |
C |
G |
G |
T |
A |
A |
G |
4 |
A |
C |
C |
A |
C |
A |
G |
T |
C |
C |
T |
G |
G |
C |
G |
G |
C |
C |
A |
T |
T |
C |
4 |
G |
T |
18 |
A |
C |
T |
G |
A |
A |
C |
G |
A |
A |
C |
A |
A |
G |
G |
2 |
T |
G |
T |
4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
A
|
A
|
C
|
-
|
-
|
C
|
C
|
-
|
A
|
G
|
-
|
C
|
C
|
T
|
G
|
G
|
T
|
G
|
T
|
4
|
T
|
G
|
A
|
G
|
C
|
G
|
C
|
A
|
T
|
C
|
C
|
G
|
C
|
C
|
A
|
G
|
G
|
G
|
G
|
T
|
G
|
T
|
T
|
G
|
A
|
A
|
29
|
A
|
A
|
-
|
T
|
G
|
-
|
G
|
G
|
T
|
C
|
A
|
C
|
A
|
G
|
G
|
A
|
G
|
-
|
A
|
-
|
C
|
C
|
2
|
2
|
A
|
25
|
A
|
A
|
2
|
-
|
A
|
C
|
G
|
A
|
A
|
-
|
G
|
C
|
A
|
T
|
T
|
G
|
C
|
G
|
C
|
T
|
A
|
G
|
G
|
T
|
A
|
C
|
G
|
G
|
C
|
T
|
G
|
T
|
A
|
G
|
G
|
A
|
G
|
C
|
G
|
G
|
3
|
C
|
C
|
T
|
C
|
A
|
C
|
G
|
A
|
A
|
C
|
-
|
G
|
-
|
-
|
-
|
G
|
T
|
2
|
A
|
T
|
A
|
A
|
C
|
-
|
T
|
T
|
G
|
T
|
-
|
G
|
-
|
5/17
|
C
|
G
|
G
|
T
|
C
|
T
|
T
|
A
|
-
|
G
|
G
|
G
|
3
|
-
|
G
|
T
|
T
|
T
|
T
|
G
|
A
|
A
|
T
|
T
|
C
|
4
|
A
|
T
|
A
|
A
|
T
|
T
|
G
|
C
|
C
|
T
|
-
|
A
|
C
|
-
|
G
|
2
|
C
|
-
|
G
|
G
|
A
|
T
|
-
|
C
|
G
|
T
|
G
|
A
|
A
|
-
|
C
|
A
|
C
|
-
|
|