|
.008 |
.109 |
.001 |
.39 |
.001 |
.002 |
.001 |
.001 |
.142 |
.0 |
.571 |
.898 |
.0 |
-- |
.032 |
.002 |
.0 |
.0 |
.027 |
.076 |
.684 |
.44 |
.124 |
.001 |
-- |
.123 |
.009 |
.257 |
.996 |
.997 |
.993 |
.985 |
.0 |
.072 |
.049 |
.008 |
.011 |
.029 |
-- |
.754 |
.018 |
.263 |
.088 |
.004 |
.007 |
.078 |
.044 |
.344 |
.332 |
.014 |
.001 |
.0 |
.0 |
.003 |
.0 |
.005 |
.05 |
.0 |
.24 |
.009 |
.003 |
.076 |
.003 |
.012 |
.0 |
.384 |
.092 |
.0 |
.056 |
.004 |
.025 |
.942 |
.002 |
.0 |
.001 |
.006 |
-- |
.014 |
.106 |
.026 |
.063 |
.02 |
.006 |
.182 |
.0 |
.005 |
.001 |
.003 |
.0 |
.0 |
.002 |
.001 |
.485 |
.026 |
.704 |
.007 |
.056 |
.0 |
.0 |
.003 |
.0 |
.0 |
.0 |
.021 |
.006 |
.0 |
.025 |
.002 |
.001 |
.193 |
.612 |
.482 |
.0 |
.003 |
.981 |
.463 |
.029 |
.001 |
.0 |
.199 |
.001 |
.059 |
.388 |
.435 |
.002 |
.003 |
.043 |
.0 |
.001 |
.018 |
.178 |
.59 |
.009 |
.006 |
.0 |
.231 |
.103 |
.346 |
.34 |
.004 |
.001 |
.005 |
.0 |
.003 |
.01 |
.0 |
.001 |
.008 |
.003 |
.049 |
.001 |
.014 |
-- |
-- |
-- |
.354 |
.019 |
.0 |
.0 |
-- |
-- |
-- |
-- |
.002 |
.014 |
.947 |
.006 |
.012 |
.014 |
.057 |
.038 |
.082 |
.766 |
.001 |
.001 |
.333 |
.019 |
.06 |
.065 |
.006 |
.199 |
.106 |
.005 |
.001 |
.101 |
.352 |
.387 |
.002 |
.17 |
.175 |
.176 |
.006 |
.003 |
.0 |
.0 |
.0 |
.001 |
.0 |
.002 |
.001 |
.0 |
.053 |
.005 |
.001 |
.025 |
.0 |
.0 |
.971 |
.0 |
.01 |
.005 |
.024 |
.213 |
.01 |
.209 |
.024 |
.343 |
.073 |
.983 |
.003 |
.087 |
.102 |
-- |
.08 |
.029 |
.04 |
.033 |
.014 |
.454 |
.496 |
-- |
-- |
.012 |
.139 |
.138 |
.026 |
.001 |
.028 |
.0 |
.0 |
.003 |
.001 |
.0 |
.002 |
.009 |
.112 |
.001 |
.003 |
.003 |
.02 |
.021 |
.045 |
.0 |
.108 |
.001 |
.089 |
.011 |
.001 |
.001 |
.001 |
.019 |
.0 |
.0 |
.008 |
.001 |
.004 |
.037 |
.016 |
.006 |
.246 |
.178 |
.2 |
.071 |
.004 |
.002 |
.0 |
.382 |
.266 |
.172 |
.016 |
.001 |
.009 |
.0 |
.0 |
.014 |
.001 |
.011 |
.577 |
.0 |
.034 |
.0 |
.999 |
.984 |
.226 |
.328 |
.0 |
.01 |
.007 |
.038 |
.033 |
.024 |
.001 |
-- |
-- |
.789 |
.0 |
.108 |
.117 |
.119 |
.009 |
.996 |
.008 |
.132 |
.127 |
.023 |
.002 |
.001 |
.001 |
.02 |
.007 |
.012 |
.005 |
.001 |
.0 |
.007 |
.0 |
.02 |
.882 |
.002 |
.204 |
.001 |
.0 |
.002 |
.006 |
.0 |
.007 |
-- |
.008 |
.003 |
.006 |
.0 |
.008 |
.002 |
.004 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.062 |
.093 |
.031 |
.015 |
.005 |
.012 |
.013 |
.027 |
.022 |
.0 |
.015 |
.004 |
.004 |
.303 |
.958 |
.004 |
.001 |
.002 |
.002 |
.01 |
.0 |
.005 |
.742 |
.002 |
.002 |
.003 |
.007 |
.005 |
.0 |
.001 |
.001 |
.002 |
.001 |
.001 |
.011 |
.003 |
.007 |
.06 |
.063 |
.33 |
.224 |
.007 |
-- |
.001 |
.0 |
.0 |
.0 |
.077 |
.003 |
.01 |
.117 |
.371 |
.0 |
.04 |
.0 |
.083 |
.012 |
.007 |
.382 |
.082 |
.05 |
.044 |
.061 |
.065 |
.005 |
.004 |
.0 |
.767 |
.128 |
.128 |
.016 |
.0 |
.001 |
.004 |
.015 |
.0 |
.003 |
.0 |
.001 |
.044 |
.002 |
.001 |
.024 |
.018 |
.0 |
.006 |
.001 |
.0 |
.062 |
.103 |
.014 |
.143 |
.0 |
.003 |
.005 |
.0 |
.276 |
.02 |
.0 |
.003 |
.0 |
.001 |
.0 |
.047 |
.001 |
.002 |
.0 |
.004 |
.0 |
.003 |
.192 |
.86 |
.956 |
.962 |
.034 |
.121 |
.004 |
.013 |
.001 |
.004 |
.0 |
.002 |
.045 |
.06 |
.058 |
.248 |
.929 |
.823 |
.473 |
.106 |
.03 |
.016 |
.019 |
.0 |
.02 |
.003 |
.002 |
.222 |
.004 |
.0 |
.058 |
.015 |
.121 |
.006 |
.0 |
.004 |
.052 |
.001 |
.004 |
.001 |
.004 |
.0 |
.0 |
.001 |
.001 |
.055 |
.001 |
.67 |
.44 |
.342 |
.0 |
.001 |
.846 |
.002 |
.0 |
.362 |
.094 |
.194 |
.071 |
.014 |
.0 |
.002 |
.119 |
.118 |
.017 |
.076 |
.0 |
.013 |
.062 |
.012 |
.053 |
.007 |
.002 |
.001 |
.002 |
.03 |
.004 |
.138 |
.001 |
.0 |
.001 |
.0 |
.0 |
.003 |
.102 |
.011 |
.021 |
-- |
.001 |
.07 |
.477 |
-- |
-- |
-- |
-- |
.066 |
.028 |
.0 |
.018 |
.028 |
.082 |
.001 |
-- |
.011 |
.001 |
.98 |
.0 |
.678 |
.002 |
.261 |
.081 |
.148 |
.001 |
.002 |
.0 |
.002 |
.199 |
.171 |
.003 |
.005 |
.001 |
.206 |
.934 |
.446 |
.015 |
.001 |
.012 |
.011 |
.002 |
.001 |
.031 |
.018 |
.003 |
.069 |
.005 |
.038 |
.039 |
.03 |
.003 |
.001 |
.048 |
.002 |
.026 |
.015 |
.117 |
.03 |
.189 |
.0 |
.0 |
.0 |
.023 |
.001 |
.183 |
.625 |
.119 |
.001 |
.537 |
.559 |
.625 |
.014 |
.456 |
.005 |
.041 |
.009 |
.004 |
.009 |
.022 |
.019 |
.01 |
.261 |
.135 |
.001 |
.013 |
.002 |
.002 |
.088 |
.009 |
.016 |
.16 |
.143 |
.062 |
.035 |
.68 |
.095 |
.0 |
.007 |
.188 |
.0 |
.326 |
.152 |
.032 |
.065 |
.014 |
.003 |
.045 |
.02 |
.012 |
.011 |
.004 |
.002 |
.001 |
.001 |
.028 |
.036 |
.267 |
.169 |
.148 |
.044 |
.058 |
.01 |
.184 |
.056 |
.12 |
.129 |
.106 |
.161 |
.003 |
.009 |
.001 |
.002 |
.001 |
.001 |
.129 |
.022 |
.021 |
.038 |
.003 |
.002 |
.001 |
.033 |
-- |
.002 |
.002 |
-- |
-- |
-- |
.002 |
.101 |
.012 |
-- |
.795 |
.044 |
.604 |
.006 |
.211 |
.525 |
.0 |
.015 |
.017 |
.003 |
.169 |
.0 |
.002 |
.0 |
.002 |
.0 |
.189 |
.145 |
-- |
-- |
.124 |
.054 |
.165 |
.0 |
.003 |
.004 |
.051 |
.006 |
.003 |
.011 |
.005 |
.001 |
.001 |
.041 |
.002 |
.064 |
.0 |
.062 |
.998 |
.0 |
.0 |
.0 |
.002 |
-- |
-- |
.302 |
.002 |
.004 |
.192 |
.005 |
.0 |
.0 |
.023 |
.611 |
.116 |
.002 |
.004 |
.305 |
.004 |
.037 |
.008 |
.091 |
.071 |
.713 |
.069 |
.032 |
.003 |
.15 |
.04 |
.038 |
.004 |
.018 |
.0 |
.001 |
.016 |
.0 |
.003 |
.009 |
.005 |
.984 |
.99 |
.273 |
.024 |
.006 |
.001 |
.001 |
.0 |
.0 |
.006 |
.988 |
.988 |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.0 |
.003 |
.002 |
-- |
.001 |
.001 |
.0 |
.0 |
.003 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.01 |
.0 |
-- |
.032 |
.99 |
.966 |
.384 |
.452 |
.681 |
.76 |
.062 |
.027 |
.517 |
.171 |
.043 |
.038 |
.006 |
.009 |
.073 |
.024 |
.01 |
.024 |
.041 |
.0 |
.004 |
-- |
.022 |
.001 |
.035 |
.053 |
.722 |
.0 |
.001 |
.0 |
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
Atxn1
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
G |
C |
G |
T |
8 |
G |
A |
C |
C |
T |
T |
G |
12 |
C |
G |
A |
G |
G |
T |
G |
T |
T |
A |
T |
T |
G |
T |
G |
C |
A |
A |
42 |
A |
T |
5 |
C |
C |
G |
8 |
A |
C |
T |
A |
G |
T |
G |
C |
G |
13 |
A |
C |
T |
A |
C |
A |
G |
3 |
G |
C |
A |
G |
A |
T |
10 |
G |
T |
9 |
A |
5 |
G |
G |
T |
G |
C |
T |
C |
C |
A |
T |
T |
T |
G |
C |
2 |
A |
9 |
T |
G |
C |
G |
C |
T |
2 |
T |
A |
A |
A |
5 |
A |
2 |
G |
C |
A |
G |
A |
28 |
12 |
G |
G |
G |
G |
A |
A |
G |
C |
T |
A |
T |
C |
A |
C |
A |
24 |
22 |
C |
T |
2 |
8 |
6 |
T |
G |
C |
A |
T |
C |
T |
T |
T |
C |
G |
2 |
2 |
A |
C |
C |
G |
G |
A |
A |
A |
T |
A |
C |
C |
6 |
G |
T |
C |
G |
3 |
2 |
G |
T |
T |
G |
14 |
G |
2 |
T |
24 |
22 |
2 |
C |
C |
C |
2 |
2 |
2 |
T |
G |
T |
G |
C |
T |
2 |
C |
G |
C |
C |
C |
C |
5 |
C |
C |
T |
C |
G |
T |
C |
A |
A |
C |
C |
A |
C |
C |
T |
G |
A |
T |
G |
C |
G |
A |
T |
4 |
2 |
C |
C |
4 |
4 |
A |
T |
C |
C |
C |
A |
4 |
G |
G |
C |
C |
C |
3 |
14 |
T |
C |
C |
A |
A |
A |
T |
G |
G |
T |
G |
A |
G |
G |
G |
G |
A |
C |
T |
C |
G |
8 |
G |
G |
A |
5 |
G |
T |
T |
C |
C |
A |
A |
G |
A |
G |
4 |
G |
A |
G |
T |
8 |
C |
C |
A |
A |
C |
A |
T |
A |
T |
A |
A |
G |
A |
C |
G |
2 |
A |
G |
T |
4 |
2 |
C |
C |
C |
A |
T |
A |
2 |
A |
T |
G |
A |
G |
C |
T |
2 |
C |
A |
T |
G |
T |
C |
T |
T |
A |
A |
T |
C |
C |
G |
A |
A |
A |
A |
A |
C |
T |
C |
16 |
2 |
4 |
2 |
G |
C |
A |
G |
T |
A |
2 |
T |
T |
G |
C |
C |
A |
T |
C |
C |
T |
A |
G |
A |
T |
T |
A |
C |
C |
C |
A |
A |
G |
A |
A |
C |
G |
T |
A |
A |
C |
T |
C |
A |
T |
A |
A |
T |
A |
A |
C |
T |
T |
T |
T |
A |
A |
T |
132 |
A |
C |
C |
G |
T |
C |
T |
A |
C |
G |
C |
G |
G |
C |
G |
C |
T |
A |
C |
G |
T |
G |
A |
T |
G |
6 |
4 |
G |
C |
C |
T |
G |
G |
G |
G |
A |
C |
A |
C |
T |
G |
T |
T |
G |
A |
G |
G |
C |
T |
G |
C |
C |
G |
A |
G |
C |
C |
A |
A |
19 |
2 |
G |
C |
T |
C |
A |
A |
G |
2 |
G |
A |
T |
G |
A |
G |
2 |
C |
G |
G |
G |
A |
G |
A |
A |
A |
C |
T |
T |
C |
14 |
A |
G |
2 |
T |
A |
G |
G |
G |
T |
T |
12 |
2 |
2 |
C |
T |
8 |
6 |
6 |
T |
G |
A |
T |
G |
G |
2 |
T |
A |
3 |
2 |
C |
C |
G |
G |
C |
C |
T |
T |
A |
C |
T |
A |
C |
2 |
G |
G |
G |
C |
C |
T |
C |
T |
T |
A |
C |
G |
T |
G |
A |
G |
A |
T |
A |
A |
A |
4 |
T |
C |
T |
20 |
4 |
2 |
A |
T |
C |
A |
G |
2 |
T |
G |
C |
G |
C |
A |
C |
G |
C |
C |
C |
T |
C |
T |
A |
T |
A |
G |
A |
T |
C |
G |
G |
A |
A |
G |
C |
T |
A |
T |
A |
A |
C |
16 |
T |
4 |
2 |
4 |
2 |
7 |
11 |
11 |
2 |
2 |
3 |
G |
T |
2 |
A |
G |
T |
A |
4 |
3 |
T |
C |
G |
8 |
T |
G |
T |
C |
C |
C |
T |
2 |
6 |
5 |
G |
C |
A |
G |
A |
A |
G |
A |
2 |
C |
8 |
20 |
A |
T |
A |
T |
T |
T |
C |
G |
14 |
A |
G |
5 |
G |
A |
G |
T |
G |
A |
C |
T |
A |
A |
T |
T |
G |
T |
T |
C |
C |
T |
A |
C |
G |
C |
C |
C |
T |
A |
A |
T |
C |
C |
G |
G |
T |
A |
G |
G |
C |
T |
3 |
10 |
8 |
C |
C |
C |
C |
A |
2 |
G |
2 |
3 |
14 |
C |
G |
G |
A |
A |
A |
A |
G |
C |
A |
G |
G |
C |
A |
4 |
G |
G |
G |
C |
T |
T |
T |
T |
2 |
12 |
8 |
C |
C |
G |
A |
T |
G |
T |
T |
C |
T |
T |
T |
T |
C |
5 |
C |
C |
A |
A |
G |
C |
G |
G |
T |
A |
C |
C |
G |
T |
C |
G |
122 |
G |
C |
G |
T |
48 |
C |
T |
A |
A |
G |
C |
T |
A |
C |
T |
A |
T |
T |
A |
A |
A |
A |
T |
C |
A |
A |
A |
G |
A |
4 |
2 |
T |
C |
A |
8 |
T |
C |
3 |
G |
C |
C |
G |
24 |
C |
T |
A |
8 |
2 |
C |
C |
C |
A |
A |
C |
A |
G |
6 |
T |
G |
A |
T |
A |
G |
T |
G |
G |
T |
A |
G |
A |
A |
T |
G |
T |
C |
A |
G |
T |
T |
A |
T |
T |
G |
T |
T |
5 |
A |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G/3
|
T
|
2
|
C
|
-
|
A
|
G
|
G
|
T
|
C
|
A
|
A
|
-
|
6
|
2
|
G
|
T
|
A
|
C
|
G/4
|
9
|
C
|
G
|
3
|
3
|
A
|
C
|
2
|
T
|
3
|
3
|
-
|
G
|
-
|
-
|
T
|
T
|
T
|
-
|
G
|
2
|
-
|
C
|
A
|
C
|
A
|
T
|
-
|
-
|
?
|
T
|
C
|
G
|
A
|
G
|
T
|
-
|
T
|
T
|
G
|
A
|
G
|
-
|
-
|
3/GC
|
C
|
-
|
G
|
-
|
-
|
2
|
T/2
|
A
|
2
|
-
|
T
|
T
|
G
|
-
|
C
|
G
|
2
|
C/7
|
-
|
G
|
-
|
C
|
A
|
A
|
A
|
T
|
C
|
-
|
73
|
G
|
G
|
G
|
-
|
G
|
2/-
|
G/-
|
T
|
G
|
9
|
G
|
28/-
|
12/-
|
A
|
C
|
C
|
C
|
G
|
C
|
-
|
T
|
A
|
G
|
C
|
A
|
G
|
4
|
G
|
24/-
|
22/-
|
T
|
C
|
-
|
8/-
|
6/-
|
2
|
T
|
5
|
12
|
2
|
T
|
C
|
-
|
A
|
A
|
C
|
-
|
-
|
C
|
T
|
-
|
T
|
A
|
T
|
T
|
G
|
C
|
3
|
-
|
2
|
-
|
3/5
|
C
|
8
|
G/A
|
3/-
|
2/-
|
T
|
8
|
2
|
A
|
-
|
A
|
2/-
|
T/-
|
24/-
|
-
|
-
|
3/CT
|
T
|
2
|
-
|
-
|
2/-
|
-
|
2
|
G
|
C
|
A
|
G
|
-
|
A
|
-
|
A
|
2
|
-
|
3
|
-
|
2
|
T
|
2
|
10
|
A
|
A
|
?
|
G
|
G
|
T
|
T
|
G
|
T
|
T
|
C
|
A
|
C
|
G
|
A
|
T
|
A
|
G
|
G
|
-
|
-
|
-
|
C/3
|
-
|
-
|
G
|
C
|
T
|
17
|
T
|
C
|
-
|
A
|
A
|
T
|
T
|
5
|
-
|
-
|
-
|
T
|
T
|
T
|
G
|
-
|
3
|
A
|
C
|
C
|
C
|
-
|
A
|
A
|
3
|
A
|
C
|
T
|
C
|
T
|
A
|
-
|
A
|
A
|
G
|
-
|
A
|
C
|
C
|
T
|
T
|
G
|
G
|
A
|
G
|
-
|
-
|
A
|
5
|
A
|
C
|
-
|
G
|
G
|
G
|
T
|
T
|
C
|
C
|
G
|
6
|
AT/3
|
G
|
C
|
G
|
-
|
A
|
-
|
C
|
A
|
A
|
4/-
|
2/-
|
G
|
G
|
G
|
G
|
C
|
C
|
-
|
T
|
C
|
G/2
|
A/-
|
A
|
2
|
3/TC
|
-
|
3
|
3/AC
|
G
|
A
|
C
|
34
|
C
|
C
|
C
|
G
|
C
|
T
|
T
|
A
|
G
|
G
|
C
|
G
|
G
|
4
|
C
|
T
|
16/-
|
-
|
4/-
|
2/-
|
A
|
T
|
G
|
A
|
G
|
T
|
-
|
3
|
49
|
A
|
2
|
2
|
2
|
2
|
T
|
T
|
C
|
G
|
C
|
G
|
9
|
33
|
G
|
T
|
T
|
T
|
C
|
G
|
T
|
G
|
G
|
T
|
T
|
C
|
5/6
|
C
|
G
|
C
|
A
|
G
|
C
|
G
|
T
|
C
|
G
|
G
|
T
|
G
|
G
|
C
|
C
|
G
|
C
|
C
|
-
|
C
|
A
|
T
|
T
|
A
|
A
|
2
|
G
|
T
|
-
|
6
|
A
|
A
|
T
|
C
|
31
|
C
|
G
|
G
|
A
|
2
|
C
|
G
|
C
|
A
|
6/-
|
4/-
|
12
|
G
|
G
|
2
|
2
|
A
|
T
|
A
|
G
|
T
|
G
|
A
|
C
|
A
|
C
|
A
|
A
|
G
|
A
|
C
|
T
|
A
|
GA/3
|
T
|
T
|
T
|
C
|
A
|
T
|
G
|
G
|
G
|
-
|
-
|
A
|
T
|
G
|
T
|
G
|
G
|
-
|
-
|
A
|
G
|
C
|
A
|
G
|
A
|
-
|
T
|
T
|
A
|
-
|
T
|
-
|
-
|
-
|
G
|
G
|
G
|
-
|
G
|
-
|
T
|
A
|
-
|
C
|
2
|
T
|
A
|
A
|
C
|
C
|
-
|
-
|
-
|
T
|
3
|
8/-
|
-
|
-
|
A
|
A
|
G
|
C
|
T
|
A
|
-
|
C
|
3
|
3/-
|
2/-
|
T
|
T
|
A
|
A
|
T
|
A
|
C
|
C
|
3
|
T
|
-
|
G
|
7/5
|
-
|
A
|
A
|
A
|
T
|
T
|
G
|
2
|
G
|
A
|
G
|
T
|
A
|
C
|
A
|
G
|
2
|
G
|
-
|
G
|
G
|
3
|
-
|
5
|
2
|
C
|
-
|
4/-
|
2/-
|
2
|
G
|
A
|
11/9
|
T
|
-
|
2
|
A
|
16
|
A
|
T
|
G
|
-
|
2
|
T
|
T
|
5/9
|
2
|
3
|
14
|
G
|
C
|
G
|
3
|
G
|
A
|
T
|
A
|
A
|
-
|
-
|
A
|
T
|
G
|
G
|
G
|
2
|
2
|
T
|
16/-
|
C
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
3/TC
|
-
|
T
|
T
|
C
|
G
|
-
|
-
|
-
|
A
|
G/5
|
-
|
C
|
2
|
3
|
3/CT
|
A
|
-
|
T/3
|
-
|
6/-
|
5/-
|
-
|
6/7
|
G
|
A
|
G
|
27
|
A
|
A/11
|
-
|
-
|
-
|
-
|
G
|
C
|
9
|
-
|
11
|
C
|
T
|
A
|
14/-
|
T
|
T
|
-
|
T
|
G
|
A
|
G
|
A
|
G
|
G
|
C
|
G
|
G
|
C
|
C
|
A
|
T/3
|
T/G
|
T
|
T
|
C
|
G
|
T
|
A
|
45
|
T
|
G
|
C
|
G
|
-
|
A
|
T
|
G
|
A
|
C
|
C
|
G
|
A
|
A
|
T
|
C
|
-
|
10/-
|
8/-
|
T
|
T
|
2
|
2
|
7
|
-
|
A
|
-
|
-
|
-
|
T
|
A
|
A
|
G
|
G
|
G
|
G
|
C
|
T
|
G
|
A
|
4
|
C/5
|
A/T
|
-
|
7
|
G/19
|
11
|
3
|
-
|
C
|
C
|
C
|
-
|
-
|
8/-
|
A
|
2
|
A
|
G
|
G
|
T
|
-
|
C
|
T
|
C
|
C
|
C
|
G
|
T
|
-
|
T
|
2
|
G
|
C
|
A
|
T
|
A
|
A
|
C
|
T
|
T
|
T
|
5
|
C
|
-
|
A
|
-
|
C
|
T
|
C
|
G
|
-
|
T
|
A
|
T
|
G
|
T
|
T
|
G
|
G
|
T
|
G
|
G
|
C
|
A
|
G
|
G
|
7
|
6
|
C
|
A
|
6
|
G
|
3/AC
|
T
|
5
|
-
|
-
|
4
|
-
|
T
|
-
|
9
|
4
|
-
|
G/4
|
C/4
|
7
|
A
|
-
|
T
|
C
|
C
|
-
|
-
|
G
|
G
|
G
|
G
|
G
|
T
|
G
|
A
|
-
|
C
|
A
|
G
|
29
|
G
|
A
|
C
|
A
|
A
|
G
|
9
|
T
|
G
|
-
|
C
|
T
|
A
|
T
|
T
|
A
|
C
|
-
|
A/-
|
C
|
C
|
A
|
G
|
A
|
-
|
2
|
G
|
|