chr start stop reference nuc variant nuc depth genic status zygosity variant ID 20 16604481 16604482 G T 19 GENIC homozygous 45450883 20 16604613 16604614 G - 4 GENIC homozygous 45904959 20 16605147 16605148 C CAAAAAAAAAAAAAAAAAA 4 GENIC homozygous 45843859 20 16605556 16605557 C T 18 GENIC homozygous 45450887 20 16605561 16605562 C T 18 GENIC homozygous 45450888 20 16605600 16605601 T C 8 GENIC homozygous 45450889 20 16605725 16605726 G A 10 GENIC homozygous 45450890 20 16605739 16605740 C T 10 GENIC homozygous 45450891 20 16605792 16605793 G A 13 GENIC homozygous 45450892 20 16606019 16606020 T C 12 GENIC homozygous 45450893 20 16606210 16606211 C T 13 GENIC homozygous 45450894 20 16606444 16606445 T C 15 GENIC homozygous 45450895 20 16606584 16606585 C T 6 GENIC homozygous 45450896 20 16607167 16607168 T C 9 GENIC homozygous 45904960 20 16608557 16608558 A G 18 GENIC homozygous 45450900 20 16608658 16608659 T C 20 GENIC homozygous 45450901 20 16608818 16608819 C T 9 GENIC homozygous 45904961 20 16608865 16608866 T - 4 GENIC homozygous 45864516 20 16609205 16609206 T C 10 GENIC homozygous 45904962 20 16610590 16610591 T C 10 GENIC homozygous 45450903 20 16611278 16611279 G A 13 GENIC homozygous 45904963 20 16611798 16611799 A G 20 GENIC homozygous 45781600 20 16611873 16611874 C T 15 GENIC possibly homozygous 45781602 20 16611995 16611996 T C 9 GENIC homozygous 45781603 20 16612076 16612077 T C 15 GENIC homozygous 45781604 20 16612493 16612494 C T 7 GENIC homozygous 45781605 20 16612514 16612515 T C 5 GENIC homozygous 45781606 20 16612711 16612712 G T 15 GENIC homozygous 45781608 20 16613071 16613072 T C 9 GENIC homozygous 45781610 20 16613477 16613478 A G 5 GENIC homozygous 45450904 20 16613851 16613852 A C 10 GENIC homozygous 45904964 20 16614429 16614430 T C 14 GENIC homozygous 45781611 20 16614432 16614433 G C 13 GENIC homozygous 45781612 20 16614457 16614458 C T 10 GENIC homozygous 45781613 20 16614485 16614486 C T 9 GENIC homozygous 45904965 20 16614642 16614643 G A 15 GENIC homozygous 45781615 20 16614650 16614668 ATAATAATAATAATAATA ------------------ 16 GENIC homozygous 45904966 20 16614798 16614799 C T 2 GENIC homozygous 45781616 20 16615117 16615118 T C 16 GENIC homozygous 45781617 20 16615715 16615716 C G 14 GENIC homozygous 45791813 20 16615778 16615779 G A 13 GENIC homozygous 45904967 20 16616420 16616421 A G 8 GENIC homozygous 45450908 20 16617923 16617924 C T 12 GENIC homozygous 45450912 20 16617931 16617932 G GA 10 GENIC possibly homozygous 45900950 20 16618299 16618300 A T 21 GENIC homozygous 45904968 20 16618917 16618918 C - 17 GENIC homozygous 45450918 20 16619535 16619536 G GC 27 GENIC homozygous 45450919 20 16619579 16619580 T C 21 GENIC homozygous 45450920 20 16619958 16619959 A - 11 GENIC homozygous 45450923 20 16620071 16620072 G C 18 GENIC homozygous 45904969 20 16620903 16620904 T TAA 4 GENIC homozygous 45781633 20 16621328 16621329 A G 11 GENIC homozygous 45781635 20 16621541 16621542 A G 14 GENIC homozygous 45781636 20 16621566 16621567 C T 12 GENIC homozygous 45904970 20 16622216 16622217 T C 11 GENIC homozygous 45781637 20 16622352 16622353 T - 23 GENIC homozygous 45781638 20 16622806 16622807 A C 15 GENIC homozygous 45781640 20 16622822 16622823 T C 16 GENIC homozygous 45781641 20 16623434 16623435 C T 14 GENIC homozygous 45781642 20 16623487 16623488 G A 13 GENIC homozygous 45781643 20 16623536 16623537 G A 12 GENIC homozygous 45781644 20 16623803 16623804 C A 7 GENIC homozygous 45623381 20 16623810 16623811 T C 7 GENIC homozygous 45623382 20 16623817 16623818 G A 5 GENIC homozygous 45781645 20 16624452 16624453 G A 3 GENIC homozygous 45781647 20 16624920 16624921 G A 14 GENIC homozygous 45904971 20 16625175 16625176 T C 16 GENIC homozygous 45781649 20 16625426 16625427 A G 16 GENIC homozygous 45781650 20 16625505 16625506 A - 9 GENIC homozygous 45904972 20 16625579 16625617 GTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGT -------------------------------------- 2 GENIC homozygous 45904973 20 16625885 16625889 ATAA ---- 4 GENIC homozygous 45450929 20 16625892 16625893 A G 3 GENIC homozygous 45904974 20 16626031 16626035 AAAC ---- 3 GENIC homozygous 45904975 20 16626304 16626305 T G 16 GENIC homozygous 45904976 20 16626305 16626306 T A 16 GENIC homozygous 45904977 20 16626372 16626373 C T 12 GENIC homozygous 45904978 20 16626691 16626692 G GCTTGCCTAGCAA 1 GENIC homozygous 45843867 20 16626460 16626461 A G 18 GENIC homozygous 45904979 20 16626682 16626683 G GGGGATTTAGC 3 GENIC homozygous 45843864 20 16626685 16626686 A AGTGG 2 GENIC homozygous 45843865 20 16626687 16626688 A AG 2 GENIC homozygous 45843866 20 16626695 16626696 C - 2 GENIC homozygous 45843868 20 16626724 16626725 G - 10 GENIC homozygous 45904980 20 16627020 16627021 T C 11 GENIC homozygous 45781656 20 16627540 16627541 G A 1 GENIC homozygous 45904981 20 16627823 16627824 G A 18 GENIC homozygous 45904982 20 16627913 16627914 A T 18 GENIC homozygous 45904983 20 16627981 16627982 G GT 18 GENIC homozygous 45859373 20 16628102 16628103 G A 21 GENIC homozygous 45450933 20 16628109 16628110 G C 21 GENIC homozygous 45450934 20 16628341 16628342 T C 10 GENIC homozygous 45450937 20 16628646 16628647 T TTTTATTTA 1 GENIC homozygous 45864519 20 16630349 16630350 C T 19 GENIC homozygous 45904984 20 16630536 16630537 G T 9 GENIC homozygous 45904985 20 16630689 16630690 C CT 19 GENIC homozygous 45904986 20 16630693 16630698 CCGGC ----- 20 GENIC homozygous 45904987 20 16630699 16630702 GGT --- 18 GENIC homozygous 45904988 20 16630704 16630705 C CAG 16 GENIC homozygous 45904989 20 16630707 16630710 CCC --- 16 GENIC homozygous 45904990 20 16630715 16630716 T TGTGGGGAGGGAG 13 GENIC homozygous 45904991 20 16630767 16630768 C T 11 GENIC homozygous 45904992 20 16630800 16630801 G GA 13 GENIC homozygous 45450956 20 16631137 16631138 A G 9 GENIC homozygous 45904993 20 16631276 16631277 T A 8 GENIC homozygous 45450963 20 16631279 16631280 C T 7 GENIC homozygous 45904994 20 16631561 16631562 T C 23 GENIC homozygous 45450967 20 16631661 16631662 G T 13 GENIC homozygous 45450969 20 16632442 16632443 A G 18 GENIC homozygous 45450982 20 16633084 16633087 AGA --- 1 GENIC homozygous 46013112 20 16633116 16633117 T - 1 GENIC homozygous 45450997 20 16633391 16633392 C T 15 GENIC homozygous 45904996 20 16634612 16634613 C T 17 GENIC homozygous 45904997 20 16634664 16634665 C T 14 GENIC homozygous 45904998 20 16635566 16635567 C T 17 GENIC homozygous 45904999 20 16635589 16635590 C T 14 GENIC homozygous 45905000 20 16635814 16635815 T G 19 GENIC homozygous 45905001 20 16636568 16636569 T A 18 GENIC homozygous 45905002 20 16636771 16636772 C T 16 GENIC homozygous 45451009 20 16636778 16636779 G A 17 GENIC homozygous 45905003 20 16637087 16637088 C T 11 GENIC homozygous 45451011 20 16637175 16637176 T C 12 GENIC homozygous 45451014 20 16637277 16637278 C T 11 GENIC homozygous 45905004 20 16637293 16637294 C T 14 GENIC homozygous 45905005 20 16637498 16637499 G T 21 GENIC homozygous 45791816 20 16637590 16637591 G T 14 GENIC homozygous 45791817 20 16637612 16637613 C T 16 GENIC homozygous 45791818 20 16637642 16637643 T C 21 GENIC homozygous 45791819 20 16637768 16637769 G T 18 GENIC homozygous 45791820 20 16637772 16637773 G A 18 GENIC homozygous 45791821 20 16637902 16637903 A G 11 GENIC homozygous 45791822 20 16637908 16637909 A - 11 GENIC homozygous 45791823 20 16637912 16637913 G T 13 GENIC homozygous 45791824 20 16637976 16637977 C T 17 GENIC homozygous 45791826 20 16638069 16638070 C T 16 GENIC homozygous 45791827 20 16638078 16638079 C G 17 GENIC homozygous 45791828 20 16638157 16638158 A T 6 GENIC homozygous 45791829 20 16638217 16638218 A G 13 GENIC homozygous 45791830 20 16638651 16638652 C T 18 GENIC homozygous 45451016 20 16638759 16638760 C T 18 GENIC homozygous 45791831 20 16638908 16638913 TTTTT ----- 3 GENIC homozygous 45864523 20 16639296 16639297 G A 12 GENIC homozygous 45791832 20 16639688 16639689 G - 5 GENIC homozygous 45791834 20 16639754 16639755 C T 7 GENIC homozygous 45905006 20 16640319 16640320 C A 12 GENIC homozygous 45451020 20 16640693 16640694 T G 6 GENIC homozygous 45451022 20 16641050 16641051 C CTATTCCTCTGCAT 7 GENIC homozygous 45905007 20 16641283 16641284 A T 18 GENIC homozygous 45451031 20 16641346 16641347 G C 12 GENIC homozygous 45905008 20 16642373 16642374 G A 14 GENIC homozygous 45905009 20 16642828 16642829 C T 8 GENIC homozygous 45451035 20 16642966 16642967 G A 13 GENIC homozygous 45451036 20 16643361 16643362 A G 15 GENIC homozygous 45451037 20 16643412 16643413 A G 14 GENIC homozygous 45451038 20 16644331 16644332 A T 10 GENIC homozygous 45451039 20 16644446 16644447 A G 6 GENIC homozygous 45451040 20 16644724 16644725 G A 7 GENIC homozygous 45905010 20 16644957 16644958 C G 16 GENIC homozygous 45451042 20 16645573 16645574 A G 15 GENIC homozygous 45451044 20 16646987 16646988 G A 14 GENIC homozygous 45905011 20 16647084 16647085 A G 12 GENIC homozygous 45451046 20 16647089 16647090 C T 15 GENIC homozygous 45451047 20 16647145 16647146 G T 11 GENIC homozygous 45905012 20 16647307 16647308 G - 9 GENIC homozygous 45451048 20 16647677 16647678 G C 11 GENIC homozygous 45451050 20 16647851 16647852 T C 17 GENIC homozygous 45451051 20 16648882 16648883 C G 20 GENIC homozygous 45905013 20 16649213 16649214 T C 11 GENIC homozygous 45451053 20 16649346 16649347 T TAA 5 GENIC heterozygous 45451054 20 16649346 16649347 T TA 5 GENIC heterozygous 45451055 20 16649836 16649837 G T 23 GENIC homozygous 45905014 20 16649991 16649992 C T 18 GENIC homozygous 45451056 20 16651285 16651286 A G 13 GENIC homozygous 45905015 20 16651657 16651658 T C 11 GENIC homozygous 45451057 20 16652057 16652077 GGCGTGGCCTTGTTGGAGTG -------------------- 4 GENIC homozygous 45864536 20 16652275 16652276 C T 14 GENIC homozygous 45905016 20 16652554 16652555 T C 5 GENIC homozygous 45905017 20 16653092 16653093 G A 12 GENIC homozygous 45905018 20 16653276 16653277 A G 8 GENIC homozygous 45905019 20 16654641 16654642 C G 2 GENIC homozygous 45820813 20 16656229 16656230 A AAAAC 8 GENIC heterozygous 45864537 20 16656809 16656813 TATC ---- 1 GENIC homozygous 45900956 20 16656866 16656874 TCTGTCTG -------- 2 GENIC homozygous 45864539 20 16657115 16657119 TATC ---- 10 GENIC homozygous 45891368 20 16657176 16657184 TCTGTCTG -------- 9 GENIC homozygous 45864541 20 16657335 16657339 ATCT ---- 3 GENIC homozygous 45843873 20 16657426 16657427 C CATCT 17 GENIC heterozygous 45864543 20 16657426 16657427 C CATCTATCT 17 GENIC heterozygous 45864544 20 16657540 16657541 A ATCTG 13 GENIC homozygous 45451071 20 16657665 16657666 C CTATCTATA 4 GENIC heterozygous 46013113 20 16658900 16658904 GGGG ---- 13 GENIC homozygous 45905020 20 16660175 16660177 TA -- 7 GENIC heterozygous 45451088 20 16662733 16662734 C T 16 GENIC homozygous 45905021 20 16664075 16664076 C T 9 GENIC homozygous 45905022 20 16664909 16664910 G A 14 GENIC homozygous 45905023 20 16665003 16665004 A G 12 GENIC homozygous 45905024 20 16665277 16665278 A G 9 GENIC homozygous 45451090 20 16666083 16666084 C CATTG 10 GENIC homozygous 45451091 20 16668628 16668629 G C 13 GENIC homozygous 45905025 20 16669752 16669753 A G 16 GENIC homozygous 45451096 20 16670418 16670419 T C 17 GENIC homozygous 45451099 20 16671567 16671568 C CGTT 9 GENIC homozygous 45451100 20 16673807 16673808 C T 22 GENIC homozygous 45905026 20 16675155 16675156 G A 17 GENIC homozygous 45905027 20 16675164 16675165 A G 17 GENIC homozygous 45905028 20 16675239 16675240 A G 17 GENIC homozygous 45451107 20 16677310 16677311 T A 1 GENIC homozygous 45843875 20 16677717 16677718 T C 6 GENIC homozygous 45451112 20 16677718 16677719 T C 7 GENIC homozygous 45451113 20 16678629 16678630 C T 17 GENIC homozygous 45905029 20 16679902 16679903 T C 18 GENIC homozygous 45791962 20 16680614 16680615 T TCAA 9 GENIC homozygous 45905030 20 16680615 16680616 T TC 9 GENIC homozygous 45905031 20 16681372 16681373 A G 21 GENIC homozygous 45451117 20 16682470 16682471 G A 16 GENIC homozygous 45905032 20 16682853 16682854 A C 13 GENIC homozygous 45451119 20 16683733 16683734 C T 17 GENIC homozygous 45905033 20 16683881 16683882 A - 21 GENIC homozygous 45791965 20 16683950 16683951 T G 36 GENIC homozygous 45451124 20 16684683 16684684 A C 16 GENIC homozygous 45905034 20 16685509 16685510 A G 17 GENIC homozygous 45451126 20 16684698 16684699 G GA 13 GENIC possibly homozygous 45905035 20 16684908 16684936 CACACACACACACACACACACACACACA ---------------------------- 9 GENIC homozygous 45905036 20 16685163 16685164 C T 19 GENIC homozygous 45905037 20 16685885 16685886 A C 12 GENIC homozygous 45451127 20 16686008 16686009 G A 18 GENIC homozygous 45905038 20 16686183 16686184 T C 21 GENIC homozygous 45451128 20 16686384 16686385 T - 7 GENIC heterozygous 45864547 20 16686944 16686945 C CACACACACACACACACAT 11 GENIC homozygous 45905039 20 16686980 16686981 A G 13 GENIC homozygous 45451130 20 16686992 16686996 ACAC ---- 17 GENIC homozygous 45451131 20 16687598 16687600 AA -- 6 GENIC heterozygous 45905040 20 16687629 16687630 C A 17 GENIC homozygous 45451134 20 16687645 16687646 C CA 15 GENIC homozygous 45451135 20 16687730 16687731 C T 11 GENIC homozygous 45905041 20 16687983 16687984 G A 7 GENIC homozygous 45905042 20 16689217 16689218 C T 17 GENIC homozygous 45905043 20 16689698 16689699 A G 27 GENIC homozygous 45451137 20 16690870 16690871 C CAGG 23 GENIC homozygous 45451138 20 16691463 16691464 C G 12 GENIC homozygous 45905044 20 16691474 16691475 A G 9 GENIC homozygous 45451140 20 16691763 16691764 C T 11 GENIC homozygous 45905045 20 16692867 16692868 C CCGCCCACTCCAACAAGGCCCCACCCACTCCAACAAGGCCACGCCCACTCCAACAGGGCCA 10 GENIC homozygous 45905046 20 16694065 16694066 G A 15 GENIC homozygous 45451141 20 16694449 16694450 C - 12 GENIC homozygous 45451142 20 16694591 16694592 T C 19 GENIC homozygous 45451143 20 16694837 16694838 T C 11 GENIC homozygous 45905047 20 16695117 16695118 A AG 13 GENIC homozygous 45905048 20 16695128 16695129 A G 17 GENIC homozygous 45781685 20 16695913 16695914 A G 13 GENIC homozygous 45781688 20 16695919 16695920 A C 15 GENIC homozygous 45781689 20 16696087 16696088 T TACACACACACACAC 8 GENIC homozygous 45859375 20 16696123 16696124 T C 8 GENIC homozygous 45879580 20 16696598 16696599 T C 5 GENIC homozygous 45451146 20 16697127 16697139 GTGTGTGTGTGT ------------ 3 GENIC heterozygous 45843880 20 16697185 16697186 T C 7 GENIC homozygous 45451147 20 16697520 16697521 G A 3 GENIC homozygous 45451148 20 16698025 16698026 G C 8 GENIC homozygous 45781698 20 16698125 16698126 C T 14 GENIC homozygous 45905049 20 16698160 16698161 T C 17 GENIC homozygous 45451149 20 16698270 16698271 T C 21 GENIC homozygous 45451150 20 16698986 16698987 G A 9 GENIC homozygous 45905050 20 16699016 16699017 G A 6 GENIC homozygous 45451152 20 16700410 16700411 A AGATGGATG 9 GENIC homozygous 45781703 20 16701386 16701387 C T 14 GENIC homozygous 45905051 20 16701640 16701641 T G 17 GENIC homozygous 45905052 20 16702392 16702393 A G 15 GENIC homozygous 45451163 20 16702474 16702475 C T 23 GENIC homozygous 45905053 20 16703622 16703623 T G 18 GENIC homozygous 45451166 20 16704070 16704071 A T 17 GENIC homozygous 46013114 20 16704399 16704400 T C 2 GENIC homozygous 45451171 20 16704416 16704417 G GGACGGACA 6 GENIC homozygous 45905054 20 16704516 16704517 A AATAG 9 GENIC homozygous 45451176 20 16704626 16704627 A G 11 GENIC homozygous 45451177 20 16704641 16704642 G GGACAGATA 7 GENIC homozygous 45900961 20 16704671 16704672 G A 18 GENIC homozygous 45451180 20 16704694 16704695 C T 17 GENIC homozygous 45451181 20 16704770 16704771 A G 17 GENIC homozygous 45451182 20 16704788 16704789 A G 19 GENIC homozygous 45451183 20 16704872 16704873 T C 18 GENIC homozygous 45451184 20 16705044 16705045 G A 17 GENIC homozygous 45905055 20 16705151 16705152 A G 6 GENIC homozygous 45451185 20 16705840 16705841 T C 13 GENIC homozygous 45451188 20 16705851 16705852 G A 13 GENIC homozygous 45905056 20 16705860 16705861 G A 12 GENIC homozygous 45905057 20 16706011 16706012 T C 18 GENIC homozygous 45451189 20 16706223 16706224 T C 14 GENIC homozygous 45451191 20 16706253 16706254 T C 13 GENIC homozygous 45451192 20 16706679 16706680 C A 16 GENIC homozygous 45905058 20 16706774 16706775 T TC 13 GENIC homozygous 45451194 20 16706775 16706776 A G 13 GENIC homozygous 45897659 20 16706777 16706778 C CTCT 13 GENIC homozygous 45897660 20 16706780 16706784 AGAC ---- 14 GENIC homozygous 45897661 20 16706843 16706844 A G 8 GENIC homozygous 45905059 20 16707045 16707046 T A 17 GENIC homozygous 45451196 20 16707140 16707141 G A 11 GENIC homozygous 45905060 20 16707167 16707168 A G 8 GENIC homozygous 45451197 20 16707576 16707577 T C 22 GENIC homozygous 45451200 20 16709874 16709875 T A 7 GENIC homozygous 45451206 20 16709927 16709928 G GA 8 GENIC heterozygous 45843881 20 16709928 16709929 A - 8 GENIC heterozygous 45739037 20 16710180 16710181 A G 18 GENIC homozygous 45451207 20 16710262 16710263 T C 17 GENIC homozygous 45451208 20 16710387 16710388 G C 11 GENIC homozygous 45791977 20 16710417 16710418 A G 8 GENIC homozygous 45451209 20 16714641 16714642 G - 3 GENIC homozygous 45905061 20 16714643 16714654 GAGAGAGAGAG ----------- 3 GENIC homozygous 45905062 20 16715876 16715877 T TCACA 4 GENIC homozygous 45905063 20 16715951 16715955 ACAA ---- 22 GENIC homozygous 45905064 20 16716759 16716760 C T 10 GENIC homozygous 45451232 20 16717044 16717045 T C 17 GENIC homozygous 45451235 20 16717143 16717144 A G 5 GENIC homozygous 45451236 20 16721676 16721717 CACGCACGCCATACACACACACACACACACACACACACACA ----------------------------------------- 2 GENIC homozygous 46013115 20 16723064 16723065 G A 16 GENIC homozygous 45905065 20 16723472 16723473 A AAC 8 GENIC homozygous 45905066 20 16723504 16723506 AC -- 10 GENIC homozygous 45905067 20 16723740 16723748 AAAAAAAA -------- 5 GENIC homozygous 45905068 20 16724018 16724019 G A 9 GENIC homozygous 45905069 20 16724030 16724031 A ACTTCTCT 8 GENIC homozygous 45451285 20 16724189 16724190 A AC 13 GENIC homozygous 45905070 20 16724277 16724278 G - 4 GENIC homozygous 45905071 20 16724279 16724342 GGTGGAGCCTAGGACCATGAGCCTCCGGAAGAGGTGGAGCCTAGGACCATGAGCCTCCGGAAG --------------------------------------------------------------- 4 GENIC homozygous 45905072 20 16724491 16724492 A G 11 GENIC homozygous 45905073 20 16724522 16724523 T C 16 GENIC homozygous 45451289 20 16724605 16724606 C T 16 GENIC homozygous 45451290 20 16724891 16724892 C T 14 GENIC homozygous 45451291 20 16725284 16725285 A G 12 GENIC homozygous 45451292 20 16725324 16725326 TA -- 8 GENIC homozygous 45451293 20 16725333 16725334 A G 8 GENIC homozygous 45781718 20 16725354 16725358 TATA ---- 5 GENIC homozygous 45905074 20 16725362 16725376 TGTGTGTGTGTATA -------------- 6 GENIC homozygous 45905075 20 16725413 16725414 T C 5 GENIC homozygous 45451297 20 16725594 16725595 A - 6 GENIC homozygous 45451298 20 16725668 16725669 G GCC 6 GENIC homozygous 45623401 20 16725686 16725687 G GA 4 GENIC homozygous 45451300 20 16726067 16726068 G A 20 GENIC homozygous 45451301 20 16726414 16726415 A G 13 GENIC homozygous 45451302 20 16726525 16726526 C CT 3 GENIC heterozygous 45879584 20 16726994 16726998 AGAC ---- 13 GENIC homozygous 45451303 20 16727347 16727348 G C 9 GENIC homozygous 45451304 20 16728526 16728527 T C 1 GENIC homozygous 45451306 20 16728539 16728540 T G 1 GENIC homozygous 45623402 20 16728541 16728542 A AG 1 GENIC homozygous 45451308 20 16728557 16728558 T G 1 GENIC homozygous 45451310 20 16728722 16728723 A AG 1 GENIC homozygous 45451317