 |  |
RGD_v3.4
Search| Landmark or Region: Examples: Stat3, Bp335, rs64562463, ENSRNOSNP2167044, D6Got99, Chr13:36,880,000..38,129,999, hypertension, kallikrein, 16, Disease:Heart, Defects, Congenital. | |
The following 983 regions match your request.
Chr10
Chr11
Chr12
Chr13
Chr14
Chr15
Chr16
Chr17
Chr18
Chr19
Chr1
Chr20
Chr2
Chr3
Chr4
Chr5
Chr6
Chr7
Chr8
| Name | Type | Description | Position | Match Score |
|---|---|---|---|---|
| Cyp3a18 | gene:RGD | ENCODES a protein that exhibits testosterone 16-alpha-hydroxylase activity AND testosterone 6-beta-hydroxylase activity AND PARTICIPATES IN linoleic acid metabolic pathway AND phase I biotransformation pathway via cytochrome P450 AND retinol metabolic pathway AND FOUND IN endoplasmic reticulum membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 2 6-dinitrotoluene | Chr12:9086752..9136606 | 40 |
| Star | gene:RGD | ENCODES a protein that exhibits cholesterol binding (inferred) AND cholesterol transporter activity (inferred) AND INVOLVED IN bile acid biosynthetic process AND biphenyl metabolic process AND brain development AND PARTICIPATES IN aldosterone biosynthetic pathway AND cortisol biosynthetic pathway AND estradiol biosynthetic pathway AND ASSOCIATED WITH Cardiomegaly AND Diabetes Mellitus Experimental AND Diabetes Mellitus Type 2 AND FOUND IN cytosol AND mitochondrial crista AND mitochondrial intermembrane space AND INTERACTS WITH (+)-pilocarpine AND (-)-citrinin AND (6aR 11aS 11bR)-10-acetyl-11-hydroxy-7 7-dimethyl-2 6 6a 7 11a 11b-hexahydro-9H-pyrrolo[1' 2':2 3]isoindolo[4 5 6-cd]indol-9-one | Chr16:70642580..70647203 | 40 |
| Fbp1 | gene:RGD | ENCODES a protein that exhibits fructose 1 6-bisphosphate 1-phosphatase activity AND monosaccharide binding AND AMP binding (ortholog) AND INVOLVED IN carbohydrate metabolic process AND cellular response to insulin stimulus AND fructose 6-phosphate metabolic process AND PARTICIPATES IN gluconeogenesis pathway AND glycolysis/gluconeogenesis pathwayfructose and mannose metabolic pathway AND ASSOCIATED WITH Fructose-1 6-Diphosphatase Deficiency (ortholog) AND FOUND IN cytosol AND cytoplasm (ortholog) AND INTERACTS WITH (-)-epigallocatechin 3-gallate AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr17:7795717..7818041 | 40 |
| Pfkp | gene:RGD | ENCODES a protein that exhibits 6-phosphofructokinase activity AND ATP binding AND fructose-6-phosphate binding AND INVOLVED IN fructose 1 6-bisphosphate metabolic process AND fructose 6-phosphate metabolic process AND glycolysis AND PARTICIPATES IN glycolysis pathway AND fructose and mannose metabolic pathway AND galactose metabolic pathway AND FOUND IN cytosol (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND N-nitrosodiethylamine AND ammonium chloride | Chr17:74760912..74823046 | 40 |
| Rps2 | gene:RGD | ENCODES a protein that exhibits protein complex binding AND structural constituent of ribosome AND fibroblast growth factor binding (ortholog) AND INVOLVED IN formation of translation preinitiation complex AND ribosomal small subunit assembly AND cellular response to interleukin-4 (ortholog) AND FOUND IN cytosolic small ribosomal subunit AND ribonucleoprotein complex AND nucleoplasm (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:13975350..13977199 | 30 |
| Gpx3 | gene:RGD | ENCODES a protein that exhibits glutathione binding AND glutathione peroxidase activity AND selenium binding AND INVOLVED IN female pregnancy AND glutathione metabolic process AND hydrogen peroxide catabolic process AND PARTICIPATES IN arachidonic acid metabolic pathway AND glutathione metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Endometrial Neoplasms AND Lung Diseases AND FOUND IN extracellular space AND INTERACTS WITH 2 2 2-tetramine AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND C60 fullerene | Chr10:40311094..40319382 | 30 |
| St3gal6 | gene:RGD | ENCODES a protein that exhibits beta-galactoside alpha-2 3-sialyltransferase activity (ortholog) AND INVOLVED IN cellular protein modification process (ortholog) AND cellular response to interleukin-6 (ortholog) AND glycolipid metabolic process (ortholog) AND PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway AND FOUND IN integral to Golgi membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr11:42893712..42937792 | 30 |
| Flt1 | gene:RGD | ENCODES a protein that exhibits ATP binding AND growth factor binding AND transmembrane receptor protein tyrosine kinase activity AND INVOLVED IN activation of MAPKK activity AND intracellular receptor mediated signaling pathway AND positive regulation of cell migration AND PARTICIPATES IN vascular endothelial growth factor signaling pathway AND axitinib pharmacodynamics pathway AND glypican signaling pathway AND ASSOCIATED WITH Acute Lung Injury AND Breast Neoplasms AND Diabetes Mellitus Experimental AND FOUND IN plasma membrane AND Golgi apparatus (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND C60 fullerene | Chr12:7858092..8035966 | 30 |
| Slc29a4 | gene:RGD | ENCODES a protein that exhibits nucleoside transmembrane transporter activity (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine (ortholog) | Chr12:12241259..12251656 | 30 |
| Xcl1 | gene:RGD | ENCODES a protein that exhibits chemokine activity (ortholog) AND chemokine receptor binding (ortholog) AND protein homodimerization activity (ortholog) AND INVOLVED IN cell-cell signaling (ortholog) AND cellular response to interleukin-4 (ortholog) AND cellular response to transforming growth factor beta stimulus (ortholog) AND PARTICIPATES IN chemokine mediated signaling pathway AND FOUND IN extracellular space (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 6-dinitrotoluene AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr13:80691195..80694638 | 30 |
| Mrpl1 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr14:14813544..14872680 | 30 |
| Comtd1 | gene:RGD | ENCODES a protein that exhibits O-methyltransferase activity (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr15:2512204..2515315 | 30 |
| Col4a1 | gene:RGD | ENCODES a protein that exhibits platelet-derived growth factor binding (ortholog) AND INVOLVED IN epithelial cell differentiation AND cellular response to amino acid stimulus (ortholog) AND neuromuscular junction development (ortholog) AND PARTICIPATES IN syndecan signaling pathway AND Entamoeba histolyca infection pathway AND cell-extracellular matrix signaling pathway AND ASSOCIATED WITH Central Nervous System Vascular Malformations (ortholog) AND Cerebral Hemorrhage (ortholog) AND Diabetic Nephropathies (ortholog) AND FOUND IN basement membrane (ortholog) AND collagen type IV (ortholog) AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND 6alpha-methylprednisolone AND D-glucose | Chr16:83045183..83157835 | 30 |
| Pfkfb3 | gene:RGD | ENCODES a protein that exhibits 6-phosphofructo-2-kinase activity (inferred) AND ATP binding (inferred) AND fructose-2 6-bisphosphate 2-phosphatase activity (inferred) AND INVOLVED IN brain development AND fructose 2 6-bisphosphate metabolic process AND PARTICIPATES IN hypoxia inducible factor pathway AND fructose and mannose metabolic pathway AND glycolysis pathway AND INTERACTS WITH N-nitrosodiethylamine AND ammonium chloride AND lactacystin | Chr17:78241182..78268272 | 30 |
| Ndst1 | gene:RGD | ENCODES a protein that exhibits deacetylase activity (ortholog) AND sulfotransferase activity (ortholog) AND INVOLVED IN MAPK cascade (ortholog) AND embryo development (ortholog) AND embryonic neurocranium morphogenesis (ortholog) AND PARTICIPATES IN heparan sulfate biosynthetic pathway AND FOUND IN Golgi membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND ammonium chloride | Chr18:56638891..56677831 | 30 |
| SS.MNS-(D2Rat183-D2Chm113)/Ayd | congenic:RGD_Rat_Strain | Congenic strain was created by backcrossing congenic strain SS.MNS-(<i>D2Mit6-D2Rat166</i>)/Lt strain into the parental Dahl Salt-sensitive (SS) strain. | Chr2:144136724..144136933 | 30 |
| SS.MNS-(D2Chm51-D2Rat341)/Ayd | congenic:RGD_Rat_Strain | Congenic strain was created by backcrossing congenic strain SS.MNS-(<i>D2Mit6-D2Rat166</i>)/Ayd strain into the parental Dahl Salt-sensitive (SS) strain. | Chr2:155664100..155664303 | 30 |
| Cldn6 | gene:RGD | ENCODES a protein that exhibits structural molecule activity (inferred) AND PARTICIPATES IN hepatitis C virus infection pathway AND FOUND IN plasma membrane (ortholog) AND tight junction (ortholog) AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND cadmium dichloride AND furan | Chr10:12944503..12947271 | 20 |
| Rgs11 | gene:RGD | ENCODES a protein that exhibits GTPase activator activity (inferred) AND signal transducer activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND intracellular signal transduction (inferred) AND positive regulation of GTPase activity (inferred) AND FOUND IN dendrite terminus (ortholog) AND protein complex (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND C60 fullerene AND ammonium chloride | Chr10:15469922..15478157 | 20 |
| Dock2 | gene:RGD | ENCODES a protein that exhibits Rac GTPase activator activity (ortholog) AND Rac guanyl-nucleotide exchange factor activity (ortholog) AND T cell receptor binding (ortholog) AND INVOLVED IN T cell activation (ortholog) AND T cell proliferation (ortholog) AND alpha-beta T cell activation (ortholog) AND PARTICIPATES IN Fc gamma receptor mediated signaling pathway AND chemokine mediated signaling pathway AND INTERACTS WITH 2 6-dinitrotoluene AND 2 6-di-tert-butyl-4-methylphenol (ortholog) AND 4 4'-diaminodiphenylmethane (ortholog) | Chr10:19207499..19660353 | 20 |
| Sec24a | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INVOLVED IN ER to Golgi vesicle-mediated transport (inferred) AND intracellular protein transport (inferred) AND PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway AND FOUND IN COPII vesicle coat (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:37208603..37283895 | 20 |
| Anxa6 | gene:RGD | ENCODES a protein that exhibits calcium-dependent phospholipid binding AND INVOLVED IN calcium ion transport (ortholog) AND regulation of muscle contraction (ortholog) AND FOUND IN apical plasma membrane AND cytoplasm AND protein complex AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:40383975..40439683 | 20 |
| Rnf187 | gene:RGD | ENCODES a protein that exhibits ubiquitin-protein ligase activity (ortholog) AND INVOLVED IN positive regulation of cell proliferation (ortholog) AND positive regulation of transcription DNA-dependent (ortholog) AND proteasomal ubiquitin-dependent protein catabolic process (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:45221784..45227683 | 20 |
| Myh10 | gene:RGD | ENCODES a protein that exhibits ADP binding (ortholog) AND ATP binding (ortholog) AND actin filament binding (ortholog) AND INVOLVED IN actin cytoskeleton organization (ortholog) AND actin filament-based movement (ortholog) AND adult heart development (ortholog) AND PARTICIPATES IN myocarditis pathway AND FOUND IN axon (ortholog) AND cell cortex (ortholog) AND cleavage furrow (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr10:55445288..55576096 | 20 |
| Eif5a | gene:RGD | ENCODES a protein that exhibits RNA binding (ortholog) AND U6 snRNA binding (ortholog) AND protein N-terminus binding (ortholog) AND INVOLVED IN aging AND negative regulation of apoptotic process AND positive regulation of muscle cell differentiation AND FOUND IN dendrite AND neuronal cell body AND annulate lamellae (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND Delta(9)-tetrahydrocannabinol | Chr10:56760289..56764689 | 20 |
| Foxn1 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (inferred) AND INVOLVED IN keratinocyte differentiation AND thymus development AND cell proliferation (ortholog) AND ASSOCIATED WITH abnormal hair growth AND athymia AND ASSOCIATED WITH Alopecia (ortholog) AND Immunologic Deficiency Syndromes (ortholog) AND Nail Diseases (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND furan | Chr10:64243323..64256847 | 20 |
| Gosr1 | gene:RGD | ENCODES a protein that exhibits SNAP receptor activity (ortholog) AND INVOLVED IN ER to Golgi vesicle-mediated transport AND retrograde transport endosome to Golgi (ortholog) AND FOUND IN Golgi apparatus AND cis-Golgi network AND integral to membrane AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr10:67407203..67442601 | 20 |
| Ccl1 | gene:RGD | ENCODES a protein that exhibits cytokine activity (ortholog) AND INVOLVED IN response to glucocorticoid stimulus AND chemotaxis (ortholog) AND PARTICIPATES IN chemokine mediated signaling pathway AND ASSOCIATED WITH Glomerulonephritis AND Nephrosis AND Asthma (ortholog) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND all-trans-retinoic acid (ortholog) | Chr10:70380498..70383276 | 20 |
| Lig3 | gene:RGD | ENCODES a protein that exhibits DNA ligase activity (ortholog) AND INVOLVED IN double-strand break repair via nonhomologous end joining (ortholog) AND mitochondrial DNA repair (ortholog) AND negative regulation of DNA recombination (ortholog) AND PARTICIPATES IN base excision repair pathway AND ASSOCIATED WITH Reperfusion Injury AND Pancreatic Neoplasms (ortholog) AND FOUND IN condensed nuclear chromosome (ortholog) AND nucleus (ortholog) AND synaptonemal complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:71000287..71021398 | 20 |
| Ccl3 | gene:RGD | ENCODES a protein that exhibits chemokine activity AND CCR1 chemokine receptor binding (ortholog) AND CCR5 chemokine receptor binding (ortholog) AND INVOLVED IN elevation of cytosolic calcium ion concentration AND inflammatory response AND leukocyte chemotaxis AND PARTICIPATES IN interleukin-12 signaling pathway AND Toll-like receptor signaling pathway AND Trypanosoma cruzi infection pathway AND ASSOCIATED WITH Arthritis Experimental AND Chagas Disease AND Colonic Neoplasms AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND extracellular region (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2-amino-2-deoxy-D-glucopyranose AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr10:71744559..71746109 | 20 |
| Usp32 | gene:RGD | ENCODES a protein that exhibits ubiquitin thiolesterase activity (ortholog) AND INVOLVED IN ubiquitin-dependent protein catabolic process (inferred) AND FOUND IN Golgi apparatus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:73256761..73374747 | 20 |
| Itga3 | gene:RGD | ENCODES a protein that exhibits collagen binding AND fibronectin binding AND integrin binding AND INVOLVED IN cell adhesion AND heart development AND maternal process involved in female pregnancy AND PARTICIPATES IN Reelin signaling pathway AND altered Reelin signaling pathway AND integrin mediated signaling pathway AND ASSOCIATED WITH Cardiomegaly AND Diabetes Mellitus Experimental AND Glomerulonephritis AND FOUND IN alpha3-beta1 integrin complex AND cell surface AND growth cone AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND losartan AND 17beta-estradiol (ortholog) | Chr10:83728710..83759576 | 20 |
| Snf8 | gene:RGD | ENCODES a protein that exhibits transcription factor binding (ortholog) AND INVOLVED IN regulation of transcription from RNA polymerase II promoter (ortholog) AND PARTICIPATES IN autophagy pathway AND endocytic pathway AND FOUND IN transcription factor complex (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 6-dinitrotoluene AND cyclosporin A | Chr10:84749033..84761230 | 20 |
| Rara | gene:RGD | ENCODES a protein that exhibits drug binding AND mRNA 5'-UTR binding AND retinoic acid receptor activity AND INVOLVED IN female pregnancy AND hippocampus development AND liver development AND PARTICIPATES IN retinoic acid signaling pathway AND acute myeloid leukemia pathway AND ASSOCIATED WITH Amyotrophic Lateral Sclerosis AND Spinal Cord Injuries AND Leukemia Promyelocytic Acute (ortholog) AND FOUND IN cytoplasm AND dendrite AND neuron projection AND INTERACTS WITH 17alpha-ethynylestradiol AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND 4-aminopyridine | Chr10:87740479..87753265 | 20 |
| Gast | gene:RGD | ENCODES a protein that exhibits hormone activity AND INVOLVED IN G-protein coupled receptor signaling pathway AND signal transduction AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine AND 6-propyl-2-thiouracil AND C60 fullerene | Chr10:89273628..89276192 | 20 |
| Stat5a | gene:RGD | ENCODES a protein that exhibits double-stranded DNA binding AND sequence-specific DNA binding AND sequence-specific DNA binding transcription factor activity AND INVOLVED IN JAK-STAT cascade AND lactation AND mammary gland involution AND PARTICIPATES IN Jak-Stat signaling pathway AND erythropoietin signaling pathway AND granulocyte-macrophage colony-stimulating factor signaling pathway AND ASSOCIATED WITH Mammary Neoplasms Experimental AND Reperfusion Injury AND Breast Neoplasms (ortholog) AND FOUND IN cytoplasm AND nucleus AND INTERACTS WITH Goe 6976 AND N-nitrosodiethylamine AND all-trans-retinol | Chr10:89795404..89819732 | 20 |
| G6pc | gene:RGD | ENCODES a protein that exhibits glucose-6-phosphatase activity AND phosphate ion binding (ortholog) AND phosphotransferase activity alcohol group as acceptor (ortholog) AND INVOLVED IN gluconeogenesis AND glucose 6-phosphate metabolic process AND glucose homeostasis AND PARTICIPATES IN altered galactose metabolic pathway AND gluconeogenesis pathway AND glycogen degradation pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Diabetes Mellitus Type 2 AND Fetal Growth Retardation AND FOUND IN intracellular membrane-bounded organelle AND endoplasmic reticulum (ortholog) AND integral to membrane (ortholog) AND INTERACTS WITH (-)-epigallocatechin 3-gallate AND 1-naphthyl isothiocyanate AND 2 3 7 8-tetrachlorodibenzodioxine | Chr10:90393531..90403485 | 20 |
| G6pc3 | gene:RGD | ENCODES a protein that exhibits glucose-6-phosphatase activity AND INVOLVED IN gluconeogenesis AND glucose 6-phosphate metabolic process AND phosphate-containing compound metabolic process AND PARTICIPATES IN gluconeogenesis pathway AND FOUND IN endoplasmic reticulum (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND ammonium chloride | Chr10:91260522..91264754 | 20 |
| Map3k3 | gene:RGD | ENCODES a protein that exhibits protein kinase activity (ortholog) AND INVOLVED IN intracellular protein kinase cascade (ortholog) AND positive regulation of I-kappaB kinase/NF-kappaB cascade (ortholog) AND protein autophosphorylation (ortholog) AND PARTICIPATES IN Erk5 MAPK signaling pathway AND c-Jun N-terminal kinases MAPK signaling pathway AND interleukin-1 signaling pathway AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:95482303..95551065 | 20 |
| Slc39a11 | gene:RGD | ENCODES a protein that exhibits metal ion transmembrane transporter activity (inferred) AND INVOLVED IN zinc ion transport (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:102863399..103189081 | 20 |
| H3f3b | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND protein heterodimerization activity (inferred) AND INVOLVED IN brain development AND response to hormone stimulus AND muscle cell differentiation (ortholog) AND PARTICIPATES IN systemic lupus erythematosus pathway AND FOUND IN nucleosome (inferred) AND nucleus (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr10:106130320..106132544 | 20 |
| Srp68 | gene:RGD | ENCODES a protein that exhibits signal recognition particle binding (ortholog) AND INVOLVED IN response to drug (ortholog) AND FOUND IN cytoplasm (ortholog) AND signal recognition particle endoplasmic reticulum targeting (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND furan | Chr10:106359742..106387284 | 20 |
| Ube2o | gene:RGD | ENCODES a protein that exhibits acid-amino acid ligase activity (inferred) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND INTERACTS WITH 2 4 6-trinitrotoluene AND C60 fullerene AND clofibrate | Chr10:106646738..106694554 | 20 |
| Mgat5b | gene:RGD | ENCODES a protein that exhibits alpha-1 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity (inferred) AND INVOLVED IN protein N-linked glycosylation (inferred) AND PARTICIPATES IN N-linked glycan biosynthetic pathway AND O-linked glycan biosynthetic pathway AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:107019869..107089319 | 20 |
| Baiap2 | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND proline-rich region binding (ortholog) AND INVOLVED IN actin filament bundle assembly (ortholog) AND dendrite development (ortholog) AND regulation of actin cytoskeleton organization (ortholog) AND PARTICIPATES IN platelet-derived growth factor signaling pathway AND FOUND IN actin cytoskeleton (ortholog) AND cell junction (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND C60 fullerene | Chr10:109351201..109413703 | 20 |
| Mrpl12 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN positive regulation of transcription DNA-dependent (ortholog) AND transcription from mitochondrial promoter (ortholog) AND FOUND IN mitochondrial large ribosomal subunit (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:109870160..109874664 | 20 |
| Usp25 | gene:RGD | ENCODES a protein that exhibits SUMO binding (ortholog) AND ubiquitin-specific protease activity (ortholog) AND INVOLVED IN protein K48-linked deubiquitination (ortholog) AND protein K63-linked deubiquitination (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr11:15799829..15907792 | 20 |
| Usp16 | gene:RGD | ENCODES a protein that exhibits cysteine-type endopeptidase activity (ortholog) AND histone binding (ortholog) AND transcription coactivator activity (ortholog) AND INVOLVED IN histone H2A K63-linked deubiquitination (ortholog) AND histone deubiquitination (ortholog) AND mitosis (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr11:27204766..27233883 | 20 |
| Itsn1 | gene:RGD | ENCODES a protein that exhibits kinase activator activity (ortholog) AND proline-rich region binding (ortholog) AND protein complex scaffold (ortholog) AND INVOLVED IN negative regulation of neuron apoptotic process (ortholog) AND positive regulation of catalytic activity (ortholog) AND positive regulation of phosphorylation (ortholog) AND PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis AND FOUND IN coated pit (ortholog) AND endocytic vesicle (ortholog) AND lamellipodium (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr11:31721528..31901963 | 20 |
| Gtpbp8 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN barrier septum assembly (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:57484578..57494406 | 20 |
| Zdhhc23 | gene:RGD | ENCODES a protein that exhibits transferase activity transferring acyl groups (inferred) AND zinc ion binding (inferred) AND INVOLVED IN protein localization to plasma membrane (ortholog) AND protein palmitoylation (ortholog) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr11:58286189..58296769 | 20 |
| Rnf168 | gene:RGD | ENCODES a protein that exhibits K63-linked polyubiquitin binding (ortholog) AND chromatin binding (ortholog) AND histone binding (ortholog) AND INVOLVED IN double-strand break repair (ortholog) AND histone H2A K63-linked ubiquitination (ortholog) AND histone H2A monoubiquitination (ortholog) AND FOUND IN nucleus (ortholog) AND site of double-strand break (ortholog) AND ubiquitin ligase complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND aflatoxin B1 (ortholog) AND benzo[a]pyrene (ortholog) | Chr11:70304917..70328010 | 20 |
| Eif4a2 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATP-dependent helicase activity (inferred) AND translation initiation factor activity (inferred) AND PARTICIPATES IN RNA transport pathway AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr11:79950592..79957185 | 20 |
| Tbx1 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND protein homodimerization activity (ortholog) AND sequence-specific DNA binding (ortholog) AND INVOLVED IN angiogenesis (ortholog) AND anterior/posterior pattern specification (ortholog) AND aorta morphogenesis (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND C60 fullerene AND methimazole | Chr11:84400980..84410631 | 20 |
| Eif3b | gene:RGD | ENCODES a protein that exhibits translation initiation factor activity (ortholog) AND INVOLVED IN regulation of translational initiation (ortholog) AND translational initiation (ortholog) AND PARTICIPATES IN RNA transport pathway AND FOUND IN eukaryotic translation initiation factor 3 complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr12:14666974..14692130 | 20 |
| Cyp3a9 | gene:RGD | ENCODES a protein that exhibits monooxygenase activity (ortholog) AND oxidoreductase activity (ortholog) AND INVOLVED IN alkaloid catabolic process (ortholog) AND drug catabolic process (ortholog) AND oxidative demethylation (ortholog) AND PARTICIPATES IN linoleic acid metabolic pathway AND phase I biotransformation pathway via cytochrome P450 AND retinol metabolic pathway AND ASSOCIATED WITH Pediatric Crohn's disease (ortholog) AND FOUND IN endoplasmic reticulum membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-di-tert-butyl-4-methylphenol AND 6-propyl-2-thiouracil | Chr12:17164384..17204589 | 20 |
| Ywhag | gene:RGD | ENCODES a protein that exhibits receptor tyrosine kinase binding AND actin binding (ortholog) AND insulin-like growth factor receptor binding (ortholog) AND INVOLVED IN protein targeting (ortholog) AND regulation of neuron differentiation (ortholog) AND regulation of synaptic plasticity (ortholog) AND PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway AND interleukin-3 signaling pathway AND mTOR signaling pathway AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr12:21859804..21888050 | 20 |
| Eif4h | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND nucleotide binding (inferred) AND translation initiation factor activity (inferred) AND INVOLVED IN developmental growth (ortholog) AND sexual reproduction (ortholog) AND ASSOCIATED WITH Williams Syndrome (ortholog) AND FOUND IN perinuclear region of cytoplasm (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr12:23148332..23164980 | 20 |
| Hip1r | gene:RGD | ENCODES a protein that exhibits actin binding (ortholog) AND phosphatidylinositol binding (ortholog) AND INVOLVED IN receptor-mediated endocytosis (ortholog) AND FOUND IN membrane AND clathrin-coated vesicle (ortholog) AND coated pit (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr12:33714225..33742792 | 20 |
| Vps33a | gene:RGD | ENCODES a protein that exhibits protein complex binding AND INVOLVED IN lysosome localization (ortholog) AND melanosome localization (ortholog) AND pigmentation (ortholog) AND FOUND IN cytoplasmic vesicle AND HOPS complex (ortholog) AND early endosome (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND pregnenolone 16alpha-carbonitrile | Chr12:34163538..34189019 | 20 |
| Ptpn11 | gene:RGD | ENCODES a protein that exhibits insulin receptor binding AND insulin receptor substrate binding AND phospholipase binding AND INVOLVED IN protein dephosphorylation AND DNA damage checkpoint (ortholog) AND activation of MAPK activity (ortholog) AND PARTICIPATES IN insulin signaling pathway AND somatostatin signaling pathway AND Interleukin-6 signaling pathway AND ASSOCIATED WITH Craniofacial Abnormalities (ortholog) AND Heart Defects Congenital (ortholog) AND Noonan Syndrome (ortholog) AND FOUND IN cytosol AND mitochondrion AND protein complex AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr12:36501886..36558055 | 20 |
| Rfc5 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND DNA binding (inferred) AND nucleoside-triphosphatase activity (inferred) AND INVOLVED IN DNA replication (inferred) AND PARTICIPATES IN mismatch repair pathway AND DNA replication pathway AND nucleotide excision repair pathway AND FOUND IN DNA replication factor C complex (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr12:40395942..40405498 | 20 |
| Git2 | gene:RGD | ENCODES a protein that exhibits ARF GTPase activator activity (inferred) AND kinase activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN regulation of ARF GTPase activity (inferred) AND PARTICIPATES IN endocytic pathway AND FOUND IN nucleoplasm (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 6-dinitrotoluene AND furan | Chr12:43117706..43158710 | 20 |
| Actr3 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND actin binding (inferred) AND INVOLVED IN positive regulation of actin filament polymerization AND positive regulation of dendrite morphogenesis AND positive regulation of filopodium assembly AND PARTICIPATES IN platelet-derived growth factor signaling pathway AND FOUND IN Golgi membrane AND actin filament AND cell leading edge AND INTERACTS WITH 2 4-dinitrotoluene AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND ammonium chloride | Chr13:37861558..37904589 | 20 |
| Tnnt2 | gene:RGD | ENCODES a protein that exhibits protein binding bridging AND troponin I binding AND ATPase activity (ortholog) AND INVOLVED IN actin crosslink formation AND cardiac muscle contraction AND muscle contraction AND PARTICIPATES IN dilated cardiomyopathy pathway AND hypertrophic cardimyopathy pathway AND ASSOCIATED WITH abnormal cardiac muscle relaxation AND ASSOCIATED WITH Cardiomyopathy Dilated (ortholog) AND Cardiomyopathy Hypertrophic (ortholog) AND Cardiomyopathy Hypertrophic Familial (ortholog) AND FOUND IN myofibril AND troponin complex AND cytoplasm (ortholog) AND INTERACTS WITH 2 2'-iminobis[1-(6-fluoro-3 4-dihydro-2H-chromen-2-yl)ethanol] AND 5-azacytidine AND 6-propyl-2-thiouracil | Chr13:48872972..48885815 | 20 |
| Mrps14 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN mitochondrion (ortholog) AND nuclear membrane (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND pregnenolone 16alpha-carbonitrile | Chr13:75614841..75620588 | 20 |
| Faslg | gene:RGD | ENCODES a protein that exhibits tumor necrosis factor receptor binding AND INVOLVED IN cellular chloride ion homeostasis AND cellular response to stress AND endosomal lumen acidification AND PARTICIPATES IN FasL mediated signaling pathway AND extrinsic apoptotic pathway AND interleukin-12 signaling pathway AND ASSOCIATED WITH neurodegeneration AND ASSOCIATED WITH Brain Ischemia AND Clonorchiasis AND Diabetes Mellitus Experimental AND FOUND IN caveola AND cytoplasmic membrane-bounded vesicle AND membrane raft AND INTERACTS WITH (S)-nicotine AND 2 3 7 8-tetrachlorodibenzodioxine AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr13:77472950..77480210 | 20 |
| Dnm3 | gene:RGD | ENCODES a protein that exhibits GTPase activity AND INVOLVED IN GTP catabolic process AND endocytosis AND filopodium assembly AND PARTICIPATES IN Fc gamma receptor mediated signaling pathway AND endocytic pathway AND FOUND IN dendritic spine AND perinuclear region of cytoplasm AND postsynaptic density AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND ammonium chloride AND cocaine | Chr13:77688376..78165178 | 20 |
| Atp1b1 | gene:RGD | ENCODES a protein that exhibits sodium:potassium-exchanging ATPase activity AND INVOLVED IN metal ion transport AND potassium ion transport AND response to hypoxia AND PARTICIPATES IN aldosterone signaling pathway AND bile acid transport pathway AND FOUND IN apical plasma membrane AND basolateral plasma membrane AND caveola AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND 3H-1 2-dithiole-3-thione | Chr13:80214056..80234576 | 20 |
| Pex19 | gene:RGD | ENCODES a protein that exhibits ATPase binding (ortholog) AND peroxisome membrane class-1 targeting sequence binding (ortholog) AND protein N-terminus binding (ortholog) AND INVOLVED IN chaperone-mediated protein folding (ortholog) AND chaperone-mediated protein transport (ortholog) AND establishment of protein localization to peroxisome (ortholog) AND FOUND IN brush border membrane AND cytoplasm AND peroxisome AND INTERACTS WITH 2 6-dinitrotoluene AND 6-propyl-2-thiouracil AND 9-cis-retinoic acid | Chr13:88122462..88139003 | 20 |
| Prox1 | gene:RGD | ENCODES a protein that exhibits DBD domain binding (ortholog) AND DNA binding (ortholog) AND LBD domain binding (ortholog) AND INVOLVED IN brain development AND liver development AND response to nutrient levels AND ASSOCIATED WITH Status Epilepticus AND FOUND IN nucleus AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND C60 fullerene | Chr13:106421541..106471350 | 20 |
| Nenf | gene:RGD | ENCODES a protein that exhibits growth factor activity (ortholog) AND INVOLVED IN positive regulation of MAPK cascade (ortholog) AND FOUND IN extracellular space (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:107368359..107377301 | 20 |
| Camk1g | gene:RGD | ENCODES a protein that exhibits calmodulin-dependent protein kinase activity AND INVOLVED IN protein phosphorylation AND FOUND IN cytoplasm AND neuron projection AND calcium- and calmodulin-dependent protein kinase complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr13:109192833..109216471 | 20 |
| Hpse | gene:RGD | ENCODES a protein that exhibits heparanase activity AND protein dimerization activity (ortholog) AND syndecan binding (ortholog) AND INVOLVED IN angiogenesis involved in wound healing (ortholog) AND cell-matrix adhesion (ortholog) AND heparan sulfate proteoglycan catabolic process (ortholog) AND PARTICIPATES IN syndecan signaling pathway AND glycosaminoglycan degradation pathway AND FOUND IN lysosome (ortholog) AND membrane raft (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND 9H-xanthine AND NAD zwitterion | Chr14:10144322..10185115 | 20 |
| Pf4 | gene:RGD | ENCODES a protein that exhibits heparin binding (ortholog) AND INVOLVED IN immune response AND protein complex assembly AND cytokine-mediated signaling pathway (ortholog) AND PARTICIPATES IN chemokine mediated signaling pathway AND cytokine mediated signaling pathway AND FOUND IN platelet alpha granule AND protein complex AND vesicle AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND C60 fullerene | Chr14:18812550..18813259 | 20 |
| Corin | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase activity AND INVOLVED IN protein processing AND proteolysis AND regulation of blood pressure AND PARTICIPATES IN atrial natriuretic peptide signaling pathway AND ASSOCIATED WITH Cardiomegaly AND Heart Failure AND Hypertension (ortholog) AND FOUND IN cytoplasmic membrane-bounded vesicle AND integral to plasma membrane AND cell surface (ortholog) AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND ammonium chloride AND cadmium dichloride | Chr14:38109932..38339631 | 20 |
| Ugdh | gene:RGD | ENCODES a protein that exhibits UDP-glucose 6-dehydrogenase activity AND INVOLVED IN gastrulation with mouth forming second (ortholog) AND PARTICIPATES IN amino sugar metabolic pathway AND ascorbate and aldarate metabolic pathway AND nucleotide sugar metabolic pathway AND FOUND IN cytosol AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:45542781..45570961 | 20 |
| Tlr6 | gene:RGD | ENCODES a protein that exhibits lipopeptide binding AND diacyl lipopeptide binding (ortholog) AND protein heterodimerization activity (ortholog) AND INVOLVED IN defense response to bacterium AND inflammatory response AND microglial cell activation involved in immune response AND PARTICIPATES IN Toll-like receptor signaling pathway AND Mycobacterium tuberculosis infection pathway AND Trypanosoma cruzi infection pathway AND ASSOCIATED WITH Enterocolitis Necrotizing AND Inflammation AND Pneumonia Bacterial AND FOUND IN Toll-like receptor 2-Toll-like receptor 6 protein complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:46089365..46100687 | 20 |
| Qdpr | gene:RGD | ENCODES a protein that exhibits 6 7-dihydropteridine reductase activity AND NADH binding AND NADPH binding AND INVOLVED IN L-phenylalanine catabolic process AND cellular response to drug AND liver development AND PARTICIPATES IN dopamine biosynthetic pathway AND epinephrine biosynthetic pathway AND norepinephrine biosynthetic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Hypertension AND Lead Poisoning AND FOUND IN cytosol AND neuron projection AND cytoplasm (ortholog) AND INTERACTS WITH (+)-pilocarpine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:70741998..70755600 | 20 |
| Drd5 | gene:RGD | ENCODES a protein that exhibits G-protein alpha-subunit binding AND dopamine receptor activity AND dopamine receptor activity coupled via Gs AND INVOLVED IN adenylate cyclase-activating G-protein coupled receptor signaling pathway AND adenylate cyclase-activating dopamine receptor signaling pathway AND dopamine receptor signaling pathway AND PARTICIPATES IN dopamine signaling pathway AND long term depression AND long term potentiation AND ASSOCIATED WITH Alzheimer Disease (ortholog) AND Attention Deficit Disorder with Hyperactivity (ortholog) AND Blepharospasm (ortholog) AND FOUND IN axon AND brush border membrane AND dendrite AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr14:77768060..77769487 | 20 |
| Lyar | gene:RGD | ENCODES a protein that exhibits metal ion binding (inferred) AND FOUND IN nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr14:77859637..77873205 | 20 |
| Add1 | gene:RGD | ENCODES a protein that exhibits T cell receptor binding AND actin filament binding (ortholog) AND protein heterodimerization activity (ortholog) AND INVOLVED IN cellular response to retinoic acid AND positive regulation of angiogenesis AND positive regulation of endocytosis AND ASSOCIATED WITH increased systemic arterial systolic blood pressure AND ASSOCIATED WITH Epilepsy Temporal Lobe AND Hypertension AND Atherosclerosis (ortholog) AND FOUND IN dendrite AND dendritic spine AND perinuclear region of cytoplasm AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr14:81750430..81808919 | 20 |
| Ap1b1 | gene:RGD | ENCODES a protein that exhibits clathrin binding (inferred) AND protein transporter activity (inferred) AND INVOLVED IN clathrin coat assembly AND PARTICIPATES IN forkhead class A signaling pathway AND FOUND IN Golgi apparatus (inferred) AND clathrin adaptor complex (inferred) AND clathrin coat (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr14:85663840..85695487 | 20 |
| Actr2 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND actin binding (inferred) AND INVOLVED IN actin cytoskeleton organization (ortholog) AND asymmetric cell division (ortholog) AND cytokinesis after meiosis (ortholog) AND PARTICIPATES IN platelet-derived growth factor signaling pathway AND FOUND IN actin cap (ortholog) AND cell cortex (ortholog) AND INTERACTS WITH 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND dibutyl phthalate AND 17alpha-ethynylestradiol (ortholog) | Chr14:100848391..100883833 | 20 |
| Zfp219 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN negative regulation of transcription DNA-dependent (ortholog) AND regulation of transcription DNA-dependent (ortholog) AND transcription DNA-dependent (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr15:27434140..27437773 | 20 |
| Supt16h | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN cellular process (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ochratoxin A | Chr15:27604676..27641794 | 20 |
| Mettl3 | gene:RGD | ENCODES a protein that exhibits mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity (ortholog) AND INVOLVED IN RNA methylation (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND (S)-nicotine (ortholog) | Chr15:27743959..27754787 | 20 |
| Myh6 | gene:RGD | ENCODES a protein that exhibits ATP binding AND calcium-dependent ATPase activity AND microfilament motor activity AND INVOLVED IN ATP catabolic process AND muscle contraction AND BMP signaling pathway (ortholog) AND PARTICIPATES IN dilated cardiomyopathy pathway AND hypertrophic cardimyopathy pathway AND myocarditis pathway AND ASSOCIATED WITH Cardiomyopathy Dilated (ortholog) AND Cardiomyopathy Hypertrophic (ortholog) AND Cardiomyopathy Hypertrophic Familial (ortholog) AND FOUND IN cytoplasm AND muscle myosin complex AND myofibril AND INTERACTS WITH (R)-noradrenaline AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine AND 3 3' 5-triiodo-L-thyronine | Chr15:33044506..33068098 | 20 |
| Tinf2 | gene:RGD | ENCODES a protein that exhibits telomeric DNA binding (ortholog) AND INVOLVED IN negative regulation of epithelial cell proliferation (ortholog) AND negative regulation of protein ADP-ribosylation (ortholog) AND negative regulation of telomere maintenance (ortholog) AND FOUND IN chromosome telomeric region (ortholog) AND nuclear telomere cap complex (ortholog) AND perinucleolar chromocenter (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND C60 fullerene | Chr15:33828924..33832032 | 20 |
| Ctsb | gene:RGD | ENCODES a protein that exhibits cysteine-type endopeptidase activity AND endopeptidase activity AND kininogen binding AND INVOLVED IN autophagy AND negative regulation of cell death AND proteolysis AND PARTICIPATES IN antigen processing and presentation pathway AND ASSOCIATED WITH Acidosis Renal Tubular AND Albuminuria AND Arthritis Experimental AND FOUND IN apical plasma membrane AND caveola AND cell surface AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr15:42402829..42423701 | 20 |
| Gnrh1 | gene:RGD | ENCODES a protein that exhibits gonadotropin hormone-releasing hormone activity (inferred) AND INVOLVED IN female pregnancy AND negative regulation of apoptotic process AND ovulation cycle AND PARTICIPATES IN gonadotropin-releasing hormone signaling pathway AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Hypogonadism (ortholog) AND FOUND IN extracellular space AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 3' 5'-cyclic GMP AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr15:47303309..47307517 | 20 |
| Tnfsf11 | gene:RGD | ENCODES a protein that exhibits cytokine activity (ortholog) AND tumor necrosis factor receptor superfamily binding (ortholog) AND INVOLVED IN positive regulation of bone resorption AND positive regulation of osteoclast differentiation AND response to radiation AND PARTICIPATES IN Interleukin-6 signaling pathway AND cytokine mediated signaling pathway AND rheumatoid arthritis pathway AND ASSOCIATED WITH Myocarditis AND Tibial Fractures AND Myocardial Infarction (ortholog) AND FOUND IN intracellular (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND ammonium chloride AND calcitriol | Chr15:59397837..59428014 | 20 |
| SS.LEW-(D16Rat112-D16Chm60)/Ayd | congenic:RGD_Rat_Strain | A sub congenic strain derived from the progenitor strain SS.LEW-(<i>D16Rat12-D16Chm23</i>)/Ayd | Chr16:64718..64959 | 20 |
| SS.LEW-(D16Rat112-D16Chm60) | strain_ont:RGD_Ontology_RDO0005134 | A+sub+congenic+strain+derived+from+the+progenitor+strain+SS. LEW-(<i>D16Rat12-D16Chm23</i>)/Ayd | Chr16:64718..64959 | 20 |
| SS.LEW-(D16Rat112-D16Chm60) | strain_ont:RGD_Ontology_RDO0006304 | A+sub+congenic+strain+derived+from+the+progenitor+strain+SS. LEW-(<i>D16Rat12-D16Chm23</i>)/Ayd | Chr16:64718..64959 | 20 |
| SS.LEW-(D16Got3-D16Rat112)/Ayd | congenic:RGD_Rat_Strain | A sub congenic strain derived from the progenitor strain SS.LEW-(<i>D16Mit2-D16Chm23</i>)/Ayd | Chr16:64718..3531727 | 20 |
| WKY.LEW-(D16Rat88-D16Rat40) | congenic:RGD_Rat_Strain | 22.6 cM segment of chr 16 from LEW/NHsd was introgressed into WKY/NCrl | Chr16:819225..60432230 | 20 |
| WKY.LEW-(D16Rat88-D16Rat40) | strain_ont:RGD_Ontology_RDO0005585 | 22.6+cM+segment+of+chr+16+from+LEW/NHsd+was+introgressed+into+WK Y/NCrl | Chr16:819225..60432230 | 20 |
| WKY.LEW-(D16Rat88-D16Rat40) | strain_ont:RGD_Ontology_RDO0005655 | 22.6+cM+segment+of+chr+16+from+LEW/NHsd+was+introgressed+into+WK Y/NCrl | Chr16:819225..60432230 | 20 |
| SS.LEW-(D16Chm36-D16Mit2)/Ayd | congenic:RGD_Rat_Strain | A sub congenic strain derived from the progenitor strain SS.LEW-(<i>D16Rat12-D16Chm23</i>)/Ayd | Chr16:4304396..4304517 | 20 |
| SS.LEW-(D16Chm36-D16Mit2) | strain_ont:RGD_Ontology_RDO0005134 | A+sub+congenic+strain+derived+from+the+progenitor+strain+SS. LEW-(<i>D16Rat12-D16Chm23</i>)/Ayd | Chr16:4304396..4304517 | 20 |
| SS.LEW-(D16Chm36-D16Mit2) | strain_ont:RGD_Ontology_RDO0006304 | A+sub+congenic+strain+derived+from+the+progenitor+strain+SS. LEW-(<i>D16Rat12-D16Chm23</i>)/Ayd | Chr16:4304396..4304517 | 20 |
| Tnnc1 | gene:RGD | ENCODES a protein that exhibits calcium ion binding AND actin filament binding (ortholog) AND calcium-dependent protein binding (ortholog) AND INVOLVED IN cardiac muscle contraction AND diaphragm contraction AND response to metal ion AND PARTICIPATES IN calcium signaling pathway AND dilated cardiomyopathy pathway AND hypertrophic cardimyopathy pathway AND ASSOCIATED WITH Cardiomyopathy Hypertrophic (ortholog) AND FOUND IN contractile fiber AND troponin complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 3'-amino-3'-deoxy-N(6) N(6)-dimethyladenosine | Chr16:6639357..6642331 | 20 |
| Dnah1 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATPase activity (inferred) AND microtubule motor activity (inferred) AND INVOLVED IN microtubule-based movement (ortholog) AND PARTICIPATES IN Huntington disease pathway AND FOUND IN cilium axoneme (inferred) AND cytoplasm (inferred) AND dynein complex (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND 6-propyl-2-thiouracil | Chr16:6693763..6754535 | 20 |
| Myo9b | gene:RGD | ENCODES a protein that exhibits ADP binding AND ATP binding AND ATP-dependent protein binding AND INVOLVED IN ATP catabolic process AND Rho protein signal transduction AND positive regulation of GTPase activity AND FOUND IN actin filament AND cytoplasm AND lamellipodium AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr16:18434261..18519220 | 20 |
| Pik3r2 | gene:RGD | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog) AND receptor tyrosine kinase binding (ortholog) AND INVOLVED IN signal transduction (inferred) AND PARTICIPATES IN FasL mediated signaling pathway AND Trail mediated signaling pathway AND epidermal growth factor/neuregulin signaling pathway AND FOUND IN cytosol (inferred) AND phosphatidylinositol 3-kinase complex (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr16:19171101..19179650 | 20 |
| Ifi30 | gene:RGD | ENCODES a protein that exhibits oxidoreductase activity acting on a sulfur group of donors (ortholog) AND INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog) AND antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog) AND negative regulation of fibroblast proliferation (ortholog) AND PARTICIPATES IN antigen processing and presentation pathway AND FOUND IN cell junction (ortholog) AND intracellular membrane-bounded organelle (ortholog) AND lysosome (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr16:19181236..19185438 | 20 |
| Uimc1 | gene:RGD | ENCODES a protein that exhibits K63-linked polyubiquitin binding (ortholog) AND histone binding (ortholog) AND retinoid X receptor binding (ortholog) AND INVOLVED IN G2/M transition DNA damage checkpoint (ortholog) AND double-strand break repair (ortholog) AND histone H2A K63-linked deubiquitination (ortholog) AND FOUND IN BRCA1-A complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH cadmium dichloride AND dibutyl phthalate AND 17alpha-ethynylestradiol (ortholog) | Chr17:15579709..15644888 | 20 |
| Bmp6 | gene:RGD | ENCODES a protein that exhibits growth factor activity AND BMP receptor binding (ortholog) AND protein heterodimerization activity (ortholog) AND INVOLVED IN osteoblast differentiation AND positive regulation of osteoblast differentiation AND response to glucocorticoid stimulus AND PARTICIPATES IN Bone morphogenetic proteins signaling pathway AND Hedgehog signaling pathway AND transforming growth factor-beta superfamily mediated signaling pathway AND ASSOCIATED WITH Brain Injuries AND Brain Ischemia AND Reperfusion Injury AND FOUND IN cytoplasm AND extracellular space AND membrane-bounded vesicle AND INTERACTS WITH 2 6-dinitrotoluene AND 2-amino-2-deoxy-D-glucopyranose AND 6-propyl-2-thiouracil | Chr17:32380199..32689295 | 20 |
| Fars2 | gene:RGD | ENCODES a protein that exhibits phenylalanine-tRNA ligase activity (ortholog) AND tRNA binding (ortholog) AND INVOLVED IN phenylalanyl-tRNA aminoacylation (ortholog) AND tRNA processing (ortholog) AND PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr17:34595255..35048596 | 20 |
| Ggps1 | gene:RGD | ENCODES a protein that exhibits farnesyltranstransferase activity (ortholog) AND geranyltranstransferase activity (ortholog) AND INVOLVED IN isoprenoid metabolic process (ortholog) AND metabolic process (ortholog) AND PARTICIPATES IN terpenoid biosynthetic pathway AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND 2-methylcholine (ortholog) AND 2-trans 6-trans 10-trans-geranylgeranyl diphosphate (ortholog) | Chr17:59458469..59470856 | 20 |
| Ryr2 | gene:RGD | ENCODES a protein that exhibits binding (ortholog) AND calcium channel activity (ortholog) AND calcium-release channel activity (ortholog) AND INVOLVED IN cytosolic calcium ion homeostasis AND response to calcium ion AND response to drug AND PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway AND calcium signaling pathway AND dilated cardiomyopathy pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Heart Failure AND Arrhythmogenic Right Ventricular Dysplasia (ortholog) AND FOUND IN Z disc AND neuron projection AND protein complex AND INTERACTS WITH (S)-nicotine AND 17beta-estradiol AND 2 2' 3 3' 6 6'-hexachlorobiphenyl | Chr17:68959042..69544816 | 20 |
| Proc | gene:RGD | ENCODES a protein that exhibits peptidase activity (ortholog) AND INVOLVED IN metabolic process (ortholog) AND negative regulation of apoptotic process (ortholog) AND negative regulation of blood coagulation (ortholog) AND PARTICIPATES IN coagulation cascade pathway AND complement system pathway AND protein C anticoagulant pathway AND ASSOCIATED WITH Protein C Deficiency (ortholog) AND Thromboembolism (ortholog) AND Thrombophilia (ortholog) AND FOUND IN extracellular space AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 6-propyl-2-thiouracil | Chr18:24563368..24573715 | 20 |
| Slc14a1 | gene:RGD | ENCODES a protein that exhibits urea transmembrane transporter activity AND water transmembrane transporter activity (ortholog) AND INVOLVED IN urea transport AND transmembrane transport (ortholog) AND urea transmembrane transport (ortholog) AND FOUND IN plasma membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr18:75024200..75048481 | 20 |
| Cd97 | gene:RGD | ASSOCIATED WITH Pancreatic Neoplasms (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND C60 fullerene AND silicon dioxide | Chr19:26089268..26108997 | 20 |
| CD97 molecule | gene_ont:RGD_Ontology_RDO0003763 | ASSOCIATED WITH Pancreatic Neoplasms (ortholog) AND INTERACTS WITH 26-dinitrotoluene AND C60 fullerene AND silicon dioxide | Chr19:26089268..26108997 | 20 |
| CD97 molecule | gene_ont:RGD_Ontology_RDO0004756 | ASSOCIATED WITH Pancreatic Neoplasms (ortholog) AND INTERACTS WITH 26-dinitrotoluene AND C60 fullerene AND silicon dioxide | Chr19:26089268..26108997 | 20 |
| CD97 molecule | gene_ont:RGD_Ontology_RDO0005309 | ASSOCIATED WITH Pancreatic Neoplasms (ortholog) AND INTERACTS WITH 26-dinitrotoluene AND C60 fullerene AND silicon dioxide | Chr19:26089268..26108997 | 20 |
| Nde1 | gene:RGD | ENCODES a protein that exhibits protein domain specific binding AND identical protein binding (ortholog) AND microtubule binding (ortholog) AND INVOLVED IN centrosome duplication (ortholog) AND cerebral cortex development (ortholog) AND establishment of chromosome localization (ortholog) AND FOUND IN centrosome (ortholog) AND kinetochore (ortholog) AND microtubule organizing center (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:777877..814260 | 10 |
| Marf1 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND nucleic acid binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN female meiosis (ortholog) AND negative regulation of phosphatase activity (ortholog) AND oogenesis (ortholog) AND FOUND IN peroxisome (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:826803..872214 | 10 |
| Parn | gene:RGD | ENCODES a protein that exhibits protein kinase binding (ortholog) AND INVOLVED IN nuclear-transcribed mRNA catabolic process nonsense-mediated decay (ortholog) AND nuclear-transcribed mRNA poly(A) tail shortening (ortholog) AND PARTICIPATES IN RNA degradation pathway AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-di-tert-butyl-4-methylphenol (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:1788754..1925032 | 10 |
| Ercc4 | gene:RGD | ENCODES a protein that exhibits TFIID-class transcription factor binding (ortholog) AND damaged DNA binding (ortholog) AND endodeoxyribonuclease activity (ortholog) AND INVOLVED IN DNA repair (ortholog) AND UV protection (ortholog) AND double-strand break repair via homologous recombination (ortholog) AND PARTICIPATES IN nucleotide excision repair pathway AND ASSOCIATED WITH Pancreatic Neoplasms (ortholog) AND Xeroderma Pigmentosum (ortholog) AND FOUND IN chromosome telomeric region (ortholog) AND nuclear chromosome telomeric region (ortholog) AND nucleotide-excision repair complex (ortholog) AND INTERACTS WITH C60 fullerene AND clofibrate AND (-)-epigallocatechin 3-gallate (ortholog) | Chr10:2144262..2177554 | 10 |
| Nubp1 | gene:RGD | ENCODES a protein that exhibits iron-sulfur cluster binding (ortholog) AND INVOLVED IN cell growth (ortholog) AND cellular iron ion homeostasis (ortholog) AND iron-sulfur cluster assembly (ortholog) AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr10:5206634..5217205 | 10 |
| Usp7 | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity AND ubiquitin-specific protease activity AND cysteine-type endopeptidase activity (ortholog) AND INVOLVED IN induction of apoptosis AND protein deubiquitination AND regulation of protein stability AND PARTICIPATES IN p53 signaling pathway AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND carbonyl sulfide | Chr10:6917612..6963452 | 10 |
| Pmm2 | gene:RGD | ENCODES a protein that exhibits phosphomannomutase activity (inferred) AND INVOLVED IN mannose biosynthetic process (inferred) AND PARTICIPATES IN amino sugar metabolic pathway AND fructose and mannose metabolic pathway AND nucleotide sugar metabolic pathway AND ASSOCIATED WITH Congenital Disorders of Glycosylation (ortholog) AND FOUND IN cytoplasm (ortholog) AND neuronal cell body (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cadmium dichloride | Chr10:7001340..7022517 | 10 |
| Alg1 | gene:RGD | ENCODES a protein that exhibits transferase activity transferring glycosyl groups (inferred) AND PARTICIPATES IN N-linked glycan biosynthetic pathway AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cadmium dichloride | Chr10:10460098..10470815 | 10 |
| Glis2 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (ortholog) AND transcription regulatory region DNA binding (ortholog) AND INVOLVED IN negative regulation of sequence-specific DNA binding transcription factor activity (ortholog) AND negative regulation of smoothened signaling pathway (ortholog) AND negative regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN nuclear speck (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND all-trans-retinoic acid AND dibutyl phthalate | Chr10:11080702..11100905 | 10 |
| Crebbp | gene:RGD | ENCODES a protein that exhibits SMAD binding AND activating transcription factor binding AND histone acetyltransferase activity AND INVOLVED IN cell proliferation AND histone acetylation AND positive regulation of transcription from RNA polymerase II promoter AND PARTICIPATES IN Hedgehog signaling pathway AND androgen signaling pathway AND canonical Wnt signaling pathway AND ASSOCIATED WITH cardiac hypertrophy AND ASSOCIATED WITH Leukemia Myeloid Acute (ortholog) AND Rubinstein-Taybi Syndrome (ortholog) AND FOUND IN nucleus AND protein complex AND transcription factor complex AND INTERACTS WITH 17beta-estradiol AND 2 6-dinitrotoluene AND 4-hydroxynon-2-enal | Chr10:11598680..11724122 | 10 |
| Mefv | gene:RGD | ENCODES a protein that exhibits actin binding (ortholog) AND INVOLVED IN inflammatory response (ortholog) AND negative regulation of inflammatory response (ortholog) AND negative regulation of interleukin-1 beta production (ortholog) AND PARTICIPATES IN NOD-like receptor signaling pathway AND ASSOCIATED WITH Asthma (ortholog) AND Familial Mediterranean Fever (ortholog) AND Lung Diseases (ortholog) AND FOUND IN microtubule associated complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND ammonium chloride AND paracetamol (ortholog) | Chr10:12059821..12069345 | 10 |
| Olr1361 | gene:RGD | ENCODES a protein that exhibits olfactory receptor activity (ortholog) AND INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (ortholog) AND sensory perception of smell (ortholog) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND raloxifene | Chr10:12199166..12200107 | 10 |
| Olr1366 | gene:RGD | ENCODES a protein that exhibits olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND phenobarbital | Chr10:12334211..12335155 | 10 |
| Olr1375 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:12520186..12521127 | 10 |
| Olr1381 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND N-acetyl-L-cysteine AND N-nitrosodiethylamine | Chr10:12706761..12707702 | 10 |
| Zfp13 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND L-methionine (ortholog) | Chr10:12846897..12855039 | 10 |
| Cldn9 | gene:RGD | ENCODES a protein that exhibits structural molecule activity (inferred) AND PARTICIPATES IN hepatitis C virus infection pathway AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND tight junction (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND cadmium dichloride | Chr10:12947423..12948854 | 10 |
| Pkmyt1 | gene:RGD | ENCODES a protein that exhibits kinase activity (ortholog) AND INVOLVED IN negative regulation of phosphatase activity (ortholog) AND PARTICIPATES IN cell cycle pathway mitotic AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND cefaloridine | Chr10:12982319..12993706 | 10 |
| Pdpk1 | gene:RGD | ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase activity AND insulin receptor binding AND protein kinase binding AND INVOLVED IN focal adhesion assembly AND activation of protein kinase B activity (ortholog) AND cellular response to insulin stimulus (ortholog) AND PARTICIPATES IN angiotensin II signaling pathway AND FasL mediated signaling pathway AND fibroblast growth factor signaling pathway AND FOUND IN cytosol AND plasma membrane AND cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:13329708..13394080 | 10 |
| Amdhd2 | gene:RGD | ENCODES a protein that exhibits N-acetylglucosamine-6-phosphate deacetylase activity (inferred) AND metal ion binding (inferred) AND INVOLVED IN N-acetylglucosamine metabolic process (inferred) AND carbohydrate metabolic process (inferred) AND PARTICIPATES IN amino sugar metabolic pathway AND nucleotide sugar metabolic pathway AND INTERACTS WITH cadmium dichloride AND indole-3-methanol AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:13407051..13415537 | 10 |
| Tbc1d24 | gene:RGD | ENCODES a protein that exhibits Rab GTPase activator activity (inferred) AND INVOLVED IN neuron projection development (ortholog) AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND 17beta-estradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:13429738..13456667 | 10 |
| Rnps1 | gene:RGD | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog) AND INVOLVED IN nuclear-transcribed mRNA catabolic process nonsense-mediated decay (ortholog) AND PARTICIPATES IN RNA transport pathway AND mRNA decay pathway AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 6-propyl-2-thiouracil AND L-ethionine | Chr10:13670753..13681591 | 10 |
| Eci1 | gene:RGD | ENCODES a protein that exhibits dodecenoyl-CoA delta-isomerase activity AND identical protein binding AND INVOLVED IN fatty acid beta-oxidation (ortholog) AND metabolic process (ortholog) AND FOUND IN mitochondrion AND mitochondrial inner membrane (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr10:13683000..13697179 | 10 |
| Tsc2 | gene:RGD | ENCODES a protein that exhibits GTPase activator activity AND protein heterodimerization activity AND 14-3-3 protein binding (ortholog) AND INVOLVED IN acute-phase response AND cell projection organization AND establishment of protein localization AND PARTICIPATES IN canonical Wnt signaling pathway AND mTOR signaling pathway AND mitogen activated protein kinase signaling pathway AND ASSOCIATED WITH Tuberous Sclerosis AND Alzheimer Disease (ortholog) AND Lymphangioleiomyomatosis (ortholog) AND FOUND IN caveola AND cytoskeletal part AND cytosol AND INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one AND 2 6-dinitrotoluene AND N-acetyl-L-cysteine | Chr10:13848210..13883189 | 10 |
| Nthl1 | gene:RGD | ENCODES a protein that exhibits DNA N-glycosylase activity (ortholog) AND DNA-(apurinic or apyrimidinic site) lyase activity (ortholog) AND double-stranded DNA binding (ortholog) AND INVOLVED IN base-excision repair AP site formation (ortholog) AND nucleotide-excision repair DNA incision 5'-to lesion (ortholog) AND PARTICIPATES IN base excision repair pathway AND FOUND IN mitochondrion (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND cadmium dichloride | Chr10:13883284..13889790 | 10 |
| Zfp598 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND clofibrate (ortholog) | Chr10:13922112..13934058 | 10 |
| Nubp2 | gene:RGD | ENCODES a protein that exhibits 4 iron 4 sulfur cluster binding (inferred) AND ATP binding (inferred) AND metal ion binding (inferred) AND FOUND IN microtubule organizing center (inferred) AND nucleus (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:14131309..14134994 | 10 |
| Mapk8ip3 | gene:RGD | ENCODES a protein that exhibits mitogen-activated protein kinase kinase binding AND JUN kinase binding (ortholog) AND MAP-kinase scaffold activity (ortholog) AND INVOLVED IN neuron projection development AND positive regulation of neuron differentiation AND JNK cascade (ortholog) AND PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway AND mitogen activated protein kinase signaling pathway AND ASSOCIATED WITH Reperfusion Injury AND FOUND IN neuron projection AND Golgi membrane (ortholog) AND axolemma (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND cefaloridine | Chr10:14147895..14186277 | 10 |
| Telo2 | gene:RGD | ENCODES a protein that exhibits protein complex binding (ortholog) AND protein complex scaffold (ortholog) AND FOUND IN cytoplasm (ortholog) AND intracellular (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:14348537..14363121 | 10 |
| Rhot2 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND GTPase activity (inferred) AND calcium ion binding (inferred) AND INVOLVED IN apoptotic process (ortholog) AND cellular homeostasis (ortholog) AND mitochondrion transport along microtubule (ortholog) AND FOUND IN integral to mitochondrial outer membrane (ortholog) AND mitochondrial inner membrane (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:15104341..15110135 | 10 |
| Nme4 | gene:RGD | ENCODES a protein that exhibits protein complex binding AND nucleoside diphosphate kinase activity (ortholog) AND INVOLVED IN CTP biosynthetic process (inferred) AND GTP biosynthetic process (inferred) AND UTP biosynthetic process (inferred) AND PARTICIPATES IN de novo pyrimidine biosynthetic pathway AND purine metabolic pathway AND pyrimidine metabolic pathway AND FOUND IN mitochondrion AND INTERACTS WITH 17alpha-ethynylestradiol AND 6-propyl-2-thiouracil AND ammonium chloride | Chr10:15360310..15364165 | 10 |
| Hba-a2 | gene:RGD | ENCODES a protein that exhibits beta-amyloid binding AND heme binding AND organic acid binding AND INVOLVED IN negative regulation of blood pressure AND protein heterooligomerization AND regulation of sensory perception of pain AND PARTICIPATES IN Plasmodium infection pathway AND Trypanosoma brucei infection pathway AND ASSOCIATED WITH Anemia (ortholog) AND Anemia Hemolytic (ortholog) AND Cyanosis (ortholog) AND FOUND IN hemoglobin complex AND cytosolic small ribosomal subunit (ortholog) AND haptoglobin-hemoglobin complex (ortholog) AND INTERACTS WITH 1 1-dichloroethene AND 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil | Chr10:15584360..15585215 | 10 |
| Mpg | gene:RGD | ENCODES a protein that exhibits alkylbase DNA N-glycosylase activity (ortholog) AND INVOLVED IN base-excision repair (ortholog) AND metabolic process (ortholog) AND PARTICIPATES IN base excision repair pathway AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:15643334..15649561 | 10 |
| Stk10 | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity (ortholog) AND protein serine/threonine kinase activity (ortholog) AND INVOLVED IN lymphocyte aggregation (ortholog) AND protein autophosphorylation (ortholog) AND regulation of lymphocyte migration (ortholog) AND FOUND IN plasma membrane (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr10:17379245..17481768 | 10 |
| Ranbp17 | gene:RGD | ENCODES a protein that exhibits protein transporter activity (inferred) AND INVOLVED IN intracellular protein transport (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH C60 fullerene AND 17alpha-ethynylestradiol (ortholog) AND daunorubicin (ortholog) | Chr10:18111581..18413103 | 10 |
| Fbll1 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND methyltransferase activity (inferred) AND INVOLVED IN rRNA processing (inferred) AND tRNA processing (inferred) AND PARTICIPATES IN ribosome biogenesis pathway AND INTERACTS WITH C60 fullerene AND furan AND valproic acid (ortholog) | Chr10:20709269..20710912 | 10 |
| Rars | gene:RGD | ENCODES a protein that exhibits ATP binding AND arginine binding AND arginine-tRNA ligase activity AND INVOLVED IN arginyl-tRNA aminoacylation AND PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway AND FOUND IN aminoacyl-tRNA synthetase multienzyme complex AND cytoplasm (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND diuron | Chr10:20721170..20745484 | 10 |
| Slu7 | gene:RGD | ENCODES a protein that exhibits pre-mRNA 3'-splice site binding (ortholog) AND second spliceosomal transesterification activity (ortholog) AND zinc ion binding (ortholog) AND INVOLVED IN RNA splicing via transesterification reactions (ortholog) AND alternative mRNA splicing via spliceosome (ortholog) AND mRNA 3'-splice site recognition (ortholog) AND PARTICIPATES IN spliceosome pathway AND FOUND IN nuclear speck (ortholog) AND small nuclear ribonucleoprotein complex (ortholog) AND spliceosomal complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:28536630..28551427 | 10 |
| Il12b | gene:RGD | ENCODES a protein that exhibits interleukin-12 alpha subunit binding AND protein heterodimerization activity AND cytokine activity (ortholog) AND INVOLVED IN natural killer cell activation involved in immune response AND sensory perception of pain AND T-helper cell differentiation (ortholog) AND PARTICIPATES IN interleukin-12 signaling pathway AND interleukin-23 signaling pathway AND interleukin-27 signaling pathway AND ASSOCIATED WITH Encephalomyelitis Autoimmune Experimental AND Sepsis AND Asthma (ortholog) AND FOUND IN extracellular space AND interleukin-12 complex AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrobenzenesulfonic acid AND 2-amino-2-deoxy-D-galactopyranose | Chr10:29558955..29568331 | 10 |
| Ublcp1 | gene:RGD | ENCODES a protein that exhibits phosphoprotein phosphatase activity (inferred) AND FOUND IN nucleolus (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND flutamide | Chr10:29612055..29627325 | 10 |
| Clint1 | gene:RGD | ENCODES a protein that exhibits clathrin binding AND INVOLVED IN clathrin coat assembly AND FOUND IN clathrin-coated vesicle AND Golgi apparatus (ortholog) AND INTERACTS WITH 2-methoxyethanol AND 6-propyl-2-thiouracil AND cadmium dichloride | Chr10:30996087..31047175 | 10 |
| Sox30 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog) AND sequence-specific DNA binding RNA polymerase II transcription factor activity (ortholog) AND INVOLVED IN regulation of transcription from RNA polymerase II promoter (ortholog) AND response to corticosteroid stimulus (ortholog) AND transcription from RNA polymerase II promoter (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND cocaine AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:31116928..31144665 | 10 |
| Adam19 | gene:RGD | ENCODES a protein that exhibits metalloendopeptidase activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN heart development (ortholog) AND membrane protein ectodomain proteolysis (ortholog) AND PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway AND ASSOCIATED WITH Heart Defects Congenital (ortholog) AND INTERACTS WITH 2-methoxyethanol AND C60 fullerene AND cocaine | Chr10:31190242..31282773 | 10 |
| Havcr2 | gene:RGD | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| hepatitis A virus cellular receptor 2 | gene_ont:RGD_Ontology_RDO0003053 | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 24-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| hepatitis A virus cellular receptor 2 | gene_ont:RGD_Ontology_RDO0003158 | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 24-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| hepatitis A virus cellular receptor 2 | gene_ont:RGD_Ontology_RDO0003763 | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 24-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| hepatitis A virus cellular receptor 2 | gene_ont:RGD_Ontology_RDO0004950 | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 24-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| hepatitis A virus cellular receptor 2 | gene_ont:RGD_Ontology_RDO0004965 | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 24-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| hepatitis A virus cellular receptor 2 | gene_ont:RGD_Ontology_RDO0005265 | ASSOCIATED WITH Asthma (ortholog) AND Cystic Fibrosis (ortholog) AND Eczema (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 24-dinitrotoluene AND C60 fullerene AND cadmium dichloride | Chr10:31585703..31610825 | 10 |
| Gnb2l1 | gene:RGD | ENCODES a protein that exhibits protein kinase C binding AND SH2 domain binding (ortholog) AND cysteine-type endopeptidase activator activity involved in apoptotic process (ortholog) AND INVOLVED IN negative regulation of translation AND regulation of establishment of protein localization to plasma membrane AND activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog) AND PARTICIPATES IN hypoxia inducible factor pathway AND insulin-like growth factor signaling pathway AND protein kinase C (PKC) signaling pathway AND FOUND IN small ribosomal subunit AND cytoplasm (ortholog) AND dendrite (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr10:34067237..34072593 | 10 |
| Olr1391 | gene:RGD | ENCODES a protein that exhibits olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride | Chr10:34818740..34819669 | 10 |
| Olr1401 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr10:34998047..34998982 | 10 |
| Gfpt2 | gene:RGD | ENCODES a protein that exhibits carbohydrate binding (inferred) AND glutamine-fructose-6-phosphate transaminase (isomerizing) activity (inferred) AND INVOLVED IN UDP-N-acetylglucosamine biosynthetic process (inferred) AND carbohydrate biosynthetic process (inferred) AND glutamine metabolic process (inferred) AND PARTICIPATES IN alanine aspartate and glutamate metabolic pathway AND amino sugar metabolic pathway AND nucleotide sugar metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Type 2 (ortholog) AND Diabetic Nephropathies (ortholog) AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH diuron AND (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:35290139..35336286 | 10 |
| Sqstm1 | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity AND protein kinase C binding AND K63-linked polyubiquitin binding (ortholog) AND INVOLVED IN positive regulation of protein phosphorylation AND protein heterooligomerization AND macroautophagy (ortholog) AND PARTICIPATES IN interleukin-1 signaling pathway AND tumor necrosis factor mediated signaling pathway AND ASSOCIATED WITH Osteitis Deformans (ortholog) AND FOUND IN pre-autophagosomal structure (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2-methoxyethanol | Chr10:35751300..35762630 | 10 |
| Mgat4b | gene:RGD | ENCODES a protein that exhibits transferase activity transferring hexosyl groups (inferred) AND INVOLVED IN carbohydrate metabolic process (inferred) AND PARTICIPATES IN N-linked glycan biosynthetic pathway AND FOUND IN membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND dibutyl phthalate | Chr10:35775757..35785551 | 10 |
| Hnrph1 | gene:RGD | ENCODES a protein that exhibits RNA binding (ortholog) AND INVOLVED IN regulation of RNA splicing (ortholog) AND FOUND IN nucleoplasm AND nucleus AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND cadmium dichloride | Chr10:35922840..35930132 | 10 |
| Rufy1 | gene:RGD | ENCODES a protein that exhibits protein transporter activity (ortholog) AND INVOLVED IN protein transport (ortholog) AND regulation of endocytosis (ortholog) AND PARTICIPATES IN endocytic pathway AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:35933369..35977968 | 10 |
| Col23a1 | gene:RGD | ENCODES a protein that exhibits heparin binding AND protein homodimerization activity AND INVOLVED IN protein homotrimerization AND FOUND IN cell surface AND extracellular space AND INTERACTS WITH C60 fullerene AND ammonium chloride AND dibutyl phthalate | Chr10:36808661..37096560 | 10 |
| Hnrnpab | gene:RGD | ENCODES a protein that exhibits DNA binding AND DNA replication origin binding AND sequence-specific DNA binding (ortholog) AND INVOLVED IN negative regulation of transcription DNA-dependent AND epithelial to mesenchymal transition (ortholog) AND positive regulation of transcription DNA-dependent (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND ribonucleoprotein complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:37117285..37123177 | 10 |
| Phf15 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INVOLVED IN histone H3 acetylation (ortholog) AND histone H4-K12 acetylation (ortholog) AND histone H4-K5 acetylation (ortholog) AND FOUND IN histone acetyltransferase complex (ortholog) AND INTERACTS WITH C60 fullerene AND cefaloridine AND phenethyl isothiocyanate | Chr10:37338457..37379931 | 10 |
| Ppp2ca | gene:RGD | ENCODES a protein that exhibits protein C-terminus binding AND protein dimerization activity AND protein serine/threonine phosphatase activity AND INVOLVED IN protein dephosphorylation AND protein heterotrimerization AND regulation of protein autophosphorylation AND PARTICIPATES IN p53 signaling pathway AND platelet-derived growth factor signaling pathway AND transforming growth factor-beta Smad dependent signaling pathway AND ASSOCIATED WITH Prostatic Neoplasms (ortholog) AND FOUND IN chromosome centromeric region (ortholog) AND cytoplasm (ortholog) AND cytosol (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:37621256..37641008 | 10 |
| Kif3a | gene:RGD | ENCODES a protein that exhibits protein complex binding AND INVOLVED IN positive regulation of receptor-mediated endocytosis AND anterior/posterior pattern specification (ortholog) AND cilium assembly (ortholog) AND PARTICIPATES IN Hedgehog signaling pathway AND FOUND IN cilium axoneme AND synaptic vesicle AND centrosome (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:39029351..39062570 | 10 |
| Il4 | gene:RGD | ENCODES a protein that exhibits cytokine activity (ortholog) AND INVOLVED IN cellular response to mercury ion AND female pregnancy AND negative regulation of acute inflammatory response AND PARTICIPATES IN Notch signaling pathway AND interleukin-12 signaling pathway AND interleukin-4 signaling pathway AND ASSOCIATED WITH Anti-Glomerular Basement Membrane Disease AND Arthritis Experimental AND Asthma AND FOUND IN extracellular space AND external side of plasma membrane (ortholog) AND INTERACTS WITH 2 4 6-trinitrobenzenesulfonic acid AND 3H-1 2-dithiole-3-thione AND D-penicillamine | Chr10:39074582..39080134 | 10 |
| Rad50 | gene:RGD | ENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog) AND ATP-dependent DNA helicase activity (ortholog) AND DNA binding (ortholog) AND INVOLVED IN protein heterooligomerization AND DNA duplex unwinding (ortholog) AND DNA recombination (ortholog) AND PARTICIPATES IN homologous recombination pathway of double-strand break repair AND non-homologous end joining pathway of double-strand break repair AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Carcinoma Ductal Breast (ortholog) AND Urologic Neoplasms (ortholog) AND FOUND IN condensed nuclear chromosome AND inclusion body AND nuclear chromatin AND INTERACTS WITH 1 3-dinitrobenzene AND 6-propyl-2-thiouracil AND N-nitrosodiethylamine | Chr10:39112733..39164694 | 10 |
| P4ha2 | gene:RGD | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog) AND INVOLVED IN oxidation-reduction process (ortholog) AND peptidyl-proline hydroxylation to 4-hydroxy-L-proline (ortholog) AND PARTICIPATES IN arginine and proline metabolic pathway AND FOUND IN endoplasmic reticulum (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:39522157..39551063 | 10 |
| Tnip1 | gene:RGD | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog) AND polyubiquitin binding (ortholog) AND ubiquitin-specific protease activity (ortholog) AND INVOLVED IN MyD88-dependent toll-like receptor signaling pathway (ortholog) AND glycoprotein biosynthetic process (ortholog) AND leukocyte cell-cell adhesion (ortholog) AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND 17beta-estradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:40319735..40366764 | 10 |
| Hand1 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND bHLH transcription factor binding (ortholog) AND enzyme binding (ortholog) AND INVOLVED IN angiogenesis (ortholog) AND blastocyst development (ortholog) AND cardiac left ventricle formation (ortholog) AND ASSOCIATED WITH Cardiomegaly AND FOUND IN cytoplasm (ortholog) AND nucleolus (ortholog) AND nucleoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND all-trans-retinoic acid AND ammonium chloride | Chr10:43423366..43425933 | 10 |
| Igtp | gene:RGD | ENCODES a protein that exhibits GTPase activity (ortholog) AND INVOLVED IN GTP catabolic process (ortholog) AND cellular response to interferon-beta (ortholog) AND PARTICIPATES IN Toxoplasma gondii infection pathway AND FOUND IN cytosol (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr10:43829273..43837092 | 10 |
| Olr1413 | gene:RGD | ENCODES a protein that exhibits olfactory receptor activity (ortholog) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND methotrexate (ortholog) | Chr10:44095885..44096832 | 10 |
| Olr1415 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:44131543..44132550 | 10 |
| Olr1455 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND indole-3-methanol | Chr10:44997581..44998510 | 10 |
| Trim17 | gene:RGD | ENCODES a protein that exhibits ubiquitin-protein ligase activity (ortholog) AND INVOLVED IN protein autoubiquitination (ortholog) AND FOUND IN intracellular (inferred) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND ammonium chloride | Chr10:45255305..45263207 | 10 |
| Guk1 | gene:RGD | ENCODES a protein that exhibits guanylate kinase activity AND INVOLVED IN ATP metabolic process AND GDP biosynthetic process AND GDP-mannose metabolic process AND PARTICIPATES IN purine metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND FOUND IN cytosol AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:45489304..45497364 | 10 |
| Arf1 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN cellular copper ion homeostasis (ortholog) AND vesicle-mediated transport (ortholog) AND PARTICIPATES IN Arf family mediated signaling pathway AND phosphatidylinositol 3-kinase class I signaling pathway AND vascular endothelial growth factor signaling pathway AND FOUND IN Golgi apparatus (ortholog) AND cytosol (ortholog) AND endomembrane system (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND DDT AND dichlorine | Chr10:45516609..45532091 | 10 |
| Llgl1 | gene:RGD | ENCODES a protein that exhibits Rab GTPase activator activity AND Rab GTPase binding AND protein kinase binding (ortholog) AND INVOLVED IN Golgi to plasma membrane transport AND axonogenesis AND positive regulation of Rab GTPase activity AND FOUND IN Golgi cis cisterna AND axon AND early endosome membrane AND INTERACTS WITH C60 fullerene AND ammonium chloride AND dibutyl phthalate | Chr10:46845810..46859100 | 10 |
| Flii | gene:RGD | ENCODES a protein that exhibits actin binding (inferred) AND INVOLVED IN multicellular organismal development (ortholog) AND FOUND IN centrosome (ortholog) AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND bromobenzene | Chr10:46860271..46874196 | 10 |
| Shmt1 | gene:RGD | ENCODES a protein that exhibits L-allo-threonine aldolase activity AND amino acid binding AND glycine hydroxymethyltransferase activity AND INVOLVED IN glycine biosynthetic process AND glycine biosynthetic process from serine AND glycine metabolic process AND PARTICIPATES IN folate mediated one-carbon metabolic pathway AND glycine metabolic pathway AND glycine serine and threonine metabolic pathway AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Ovarian Neoplasms (ortholog) AND FOUND IN cytosol AND cytoplasm (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND dibutyl phthalate | Chr10:46936605..46964779 | 10 |
| Dhrs7b | gene:RGD | ENCODES a protein that exhibits nucleotide binding (inferred) AND oxidoreductase activity (inferred) AND FOUND IN integral to membrane (inferred) AND peroxisomal membrane (inferred) AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND amiodarone | Chr10:46971430..47003953 | 10 |
| Map2k3 | gene:RGD | ENCODES a protein that exhibits MAP kinase kinase activity (ortholog) AND protein kinase binding (ortholog) AND INVOLVED IN MAPK cascade (ortholog) AND activation of MAPK activity (ortholog) AND cardiac muscle contraction (ortholog) AND PARTICIPATES IN p38 MAPK signaling pathway AND interleukin-12 signaling pathway AND tumor necrosis factor mediated signaling pathway AND ASSOCIATED WITH Astrocytoma (ortholog) AND Glioblastoma (ortholog) AND INTERACTS WITH 1-naphthyl isothiocyanate AND 2 6-dinitrotoluene AND N-acetyl-L-cysteine | Chr10:47075270..47096617 | 10 |
| Slc47a1 | gene:RGD | ENCODES a protein that exhibits drug transmembrane transporter activity AND monovalent cation:hydrogen antiporter activity AND INVOLVED IN drug transmembrane transport AND drug transport AND organic cation transport AND FOUND IN membrane-bounded vesicle AND INTERACTS WITH C60 fullerene AND paraquat AND tetraethylammonium | Chr10:47514258..47548353 | 10 |
| Rnf112 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND GTPase activity (inferred) AND zinc ion binding (inferred) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-di-tert-butyl-4-methylphenol AND ammonium chloride AND chlorpyrifos | Chr10:47599958..47605503 | 10 |
| Epn2 | gene:RGD | ENCODES a protein that exhibits lipid binding (inferred) AND INVOLVED IN regulation of endocytosis AND Notch signaling pathway (ortholog) AND embryonic organ development (ortholog) AND PARTICIPATES IN endocytic pathway AND FOUND IN clathrin coat of endocytic vesicle AND INTERACTS WITH 2-ethoxyethanol AND 2-methoxyethanol AND C60 fullerene | Chr10:47677508..47739193 | 10 |
| Prpsap2 | gene:RGD | ENCODES a protein that exhibits magnesium ion binding (inferred) AND ribose phosphate diphosphokinase activity (inferred) AND INVOLVED IN nucleotide biosynthetic process (inferred) AND FOUND IN protein complex AND ribose phosphate diphosphokinase complex AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:47890667..47925430 | 10 |
| Ncor1 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II regulatory region DNA binding AND chromatin binding AND estrogen receptor binding AND INVOLVED IN cerebellum development AND lactation AND negative regulation of gene expression AND PARTICIPATES IN Notch signaling pathway AND androgen signaling pathway AND cortisol signaling pathway AND ASSOCIATED WITH Hypothyroidism AND Polycystic Ovary Syndrome AND social behavior AND FOUND IN cytoplasm AND nucleus AND perinuclear region of cytoplasm AND INTERACTS WITH 17beta-estradiol AND 2 4-dinitrotoluene AND C60 fullerene | Chr10:48481110..48628538 | 10 |
| Trim16 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND NACHT domain binding (ortholog) AND interleukin-1 binding (ortholog) AND INVOLVED IN histone H3 acetylation (ortholog) AND histone H4 acetylation (ortholog) AND positive regulation of interleukin-1 beta secretion (ortholog) AND FOUND IN PML body (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND 17beta-estradiol (ortholog) | Chr10:48987004..49009696 | 10 |
| Map2k4 | gene:RGD | ENCODES a protein that exhibits ATP binding AND JUN kinase kinase activity AND MAP kinase kinase activity AND INVOLVED IN JNK cascade AND activation of JUN kinase activity AND positive regulation of DNA replication AND PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway AND c-Jun N-terminal kinases MAPK signaling pathway AND Interleukin-6 signaling pathway AND ASSOCIATED WITH Carcinoma Ductal Breast (ortholog) AND Ovarian Neoplasms (ortholog) AND Pancreatic Neoplasms (ortholog) AND FOUND IN axon part AND cytosol AND dendrite cytoplasm AND INTERACTS WITH N-acetyl-L-cysteine AND cadmium dichloride AND copper atom | Chr10:52009149..52041599 | 10 |
| Zfp18 | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND sequence-specific DNA binding transcription factor activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN transcription DNA-dependent (inferred) AND viral reproduction (inferred) AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:52518940..52533893 | 10 |
| Myh3 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND actin binding (inferred) AND calmodulin binding (inferred) AND PARTICIPATES IN myocarditis pathway AND FOUND IN contractile fiber (ortholog) AND myosin complex (ortholog) AND INTERACTS WITH C60 fullerene AND Delta(9)-tetrahydrocannabinol AND ammonium chloride | Chr10:53776858..53800677 | 10 |
| Gas7 | gene:RGD | ENCODES a protein that exhibits actin filament binding (ortholog) AND INVOLVED IN actin filament bundle assembly (ortholog) AND actin filament polymerization (ortholog) AND neuron differentiation (ortholog) AND FOUND IN actin filament (ortholog) AND ruffle (ortholog) AND INTERACTS WITH (S)-colchicine AND 3H-1 2-dithiole-3-thione AND C60 fullerene | Chr10:54312438..54403868 | 10 |
| Stx8 | gene:RGD | ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog) AND INVOLVED IN endosome to lysosome transport AND vesicle fusion AND vesicle-mediated transport AND FOUND IN SNARE complex AND late endosome membrane AND lysosomal membrane AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione | Chr10:54700557..54942042 | 10 |
| Pik3r5 | gene:RGD | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity AND INVOLVED IN regulation of phosphatidylinositol 3-kinase activity AND PARTICIPATES IN eicosanoids signaling pathway AND ephrin - ephrin receptor bidirectional signaling axis AND phosphatidylinositol 3-kinase class I signaling pathway AND FOUND IN phosphatidylinositol 3-kinase complex AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 2 6-di-tert-butyl-4-methylphenol (ortholog) AND 3-methylcholanthrene (ortholog) | Chr10:55227872..55248301 | 10 |
| Arhgef15 | gene:RGD | ENCODES a protein that exhibits Rho guanyl-nucleotide exchange factor activity (ortholog) AND INVOLVED IN negative regulation of synapse maturation (ortholog) AND regulation of catalytic activity (ortholog) AND PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis AND FOUND IN dendrite (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND cobalt dichloride (ortholog) | Chr10:55703919..55716219 | 10 |
| Pfas | gene:RGD | ENCODES a protein that exhibits phosphoribosylformylglycinamidine synthase activity (ortholog) AND INVOLVED IN glutamine metabolic process AND response to drug AND ribonucleoside monophosphate biosynthetic process AND PARTICIPATES IN de novo purine biosynthetic pathway AND purine metabolic pathway AND ASSOCIATED WITH Carcinoma Hepatocellular AND Diabetes Mellitus Experimental AND INTERACTS WITH C60 fullerene AND 17beta-estradiol (ortholog) AND benzo[a]pyrene (ortholog) | Chr10:55745617..55761944 | 10 |
| Vamp2 | gene:RGD | ENCODES a protein that exhibits SNARE binding AND myosin binding AND protein C-terminus binding AND INVOLVED IN protein complex assembly AND protein transport AND regulation of exocytosis AND PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway AND insulin secretion pathway AND vasopressin signaling pathway AND FOUND IN SNARE complex AND intracellular membrane-bounded organelle AND intracellular organelle AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 3H-1 2-dithiole-3-thione AND C60 fullerene | Chr10:55848264..55852132 | 10 |
| Per1 | gene:RGD | ENCODES a protein that exhibits E-box binding (ortholog) AND RNA polymerase II core promoter proximal region sequence-specific DNA binding (ortholog) AND protein binding transcription factor activity (ortholog) AND INVOLVED IN circadian rhythm AND circadian regulation of gene expression (ortholog) AND negative regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 4-dinitrotoluene AND C60 fullerene | Chr10:55859851..55868747 | 10 |
| Cntrob | gene:RGD | ENCODES a protein that exhibits protein domain specific binding (ortholog) AND INVOLVED IN centriole replication (ortholog) AND centrosome separation (ortholog) AND cytokinesis (ortholog) AND FOUND IN centriole (ortholog) AND centrosome (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cobalt dichloride (ortholog) | Chr10:56094489..56116421 | 10 |
| Cyb5d1 | gene:RGD | ENCODES a protein that exhibits heme binding (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr10:56188328..56189804 | 10 |
| Kdm6b | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog) AND INVOLVED IN histone demethylation (ortholog) AND negative regulation of transcription from RNA polymerase II promoter (ortholog) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND benzo[a]pyrene (ortholog) | Chr10:56194131..56202139 | 10 |
| Efnb3 | gene:RGD | ENCODES a protein that exhibits ephrin receptor binding (ortholog) AND INVOLVED IN adult walking behavior (ortholog) AND axon choice point recognition (ortholog) AND axon guidance (ortholog) AND PARTICIPATES IN altered ephrin - ephrin receptor bidirectional signaling pathway AND ephrin - ephrin receptor bidirectional signaling axis AND FOUND IN membrane (inferred) AND INTERACTS WITH C60 fullerene AND cocaine AND furan | Chr10:56373322..56379316 | 10 |
| Senp3 | gene:RGD | ENCODES a protein that exhibits ubiquitin-specific protease activity (ortholog) AND INVOLVED IN protein metabolic process (ortholog) AND FOUND IN MLL1 complex (ortholog) AND nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cadmium dichloride | Chr10:56490584..56499367 | 10 |
| Polr2a | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND protein kinase activity (ortholog) AND ubiquitin protein ligase binding (ortholog) AND INVOLVED IN protein phosphorylation (ortholog) AND transcription from RNA polymerase II promoter (ortholog) AND PARTICIPATES IN Huntington disease pathway AND purine metabolic pathway AND pyrimidine metabolic pathway AND FOUND IN DNA-directed RNA polymerase II core complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND C60 fullerene | Chr10:56552872..56579172 | 10 |
| Zbtb4 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND diuron AND ochratoxin A | Chr10:56596070..56602532 | 10 |
| Ctdnep1 | gene:RGD | ENCODES a protein that exhibits protein serine/threonine phosphatase activity (ortholog) AND INVOLVED IN nuclear envelope organization (ortholog) AND positive regulation of triglyceride biosynthetic process (ortholog) AND protein dephosphorylation (ortholog) AND FOUND IN Nem1-Spo7 phosphatase complex (ortholog) AND cytoplasm (ortholog) AND endoplasmic reticulum membrane (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND cocaine | Chr10:56826157..56835292 | 10 |
| Gabarap | gene:RGD | ENCODES a protein that exhibits GABA receptor binding AND beta-tubulin binding (ortholog) AND microtubule binding (ortholog) AND INVOLVED IN protein transport AND apoptotic process (ortholog) AND microtubule cytoskeleton organization (ortholog) AND PARTICIPATES IN autophagy pathway AND FOUND IN cell body AND perinuclear region of cytoplasm AND Golgi apparatus (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND ammonium chloride AND dibutyl phthalate | Chr10:56837772..56840707 | 10 |
| Asgr1 | gene:RGD | ENCODES a protein that exhibits asialoglycoprotein receptor activity AND protein homodimerization activity (ortholog) AND INVOLVED IN cellular response to extracellular stimulus (ortholog) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2-acetamidofluorene AND C60 fullerene | Chr10:56899266..56903173 | 10 |
| Asgr2 | gene:RGD | ENCODES a protein that exhibits carbohydrate binding (inferred) AND INVOLVED IN bone mineralization AND glycoprotein metabolic process (ortholog) AND lipid homeostasis (ortholog) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil | Chr10:56942683..56955742 | 10 |
| Bcl6b | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND INVOLVED IN negative regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND L-ethionine | Chr10:57063162..57068306 | 10 |
| Alox15 | gene:RGD | ENCODES a protein that exhibits arachidonate 12-lipoxygenase activity AND arachidonate 15-lipoxygenase activity AND hepoxilin A3 synthase activity AND INVOLVED IN arachidonic acid metabolic process AND hepoxilin biosynthetic process AND lipoxygenase pathway AND PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism AND atherosclerosis pathway AND interleukin-4 signaling pathway AND ASSOCIATED WITH abnormal apoptosis AND ASSOCIATED WITH Brain Ischemia AND Glomerulonephritis AND Heart Failure AND FOUND IN cytosol AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND dioxygen | Chr10:57185939..57194388 | 10 |
| Pld2 | gene:RGD | ENCODES a protein that exhibits phospholipase D activity AND protein kinase C binding AND INVOLVED IN neuron projection development AND phospholipid catabolic process AND positive regulation of cell adhesion AND PARTICIPATES IN Arf family mediated signaling pathway AND mTOR signaling pathwayFc gamma receptor mediated signaling pathway AND ASSOCIATED WITH vascular smooth muscle hypertrophy AND ASSOCIATED WITH Heart Failure AND Myocardial Reperfusion Injury AND Reperfusion Injury AND FOUND IN Golgi apparatus AND caveola AND lamellipodium AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND N-nitrosodiethylamine | Chr10:57388474..57439063 | 10 |
| Rnf167 | gene:RGD | ENCODES a protein that exhibits ubiquitin-protein ligase activity (ortholog) AND INVOLVED IN negative regulation of cell cycle (ortholog) AND protein polyubiquitination (ortholog) AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:57527033..57531325 | 10 |
| C1qbp | gene:RGD | ENCODES a protein that exhibits complement component C1q binding AND protein kinase C binding AND INVOLVED IN immune response (inferred) AND FOUND IN cytoplasm AND extracellular space AND nucleus AND INTERACTS WITH (R)-adrenaline AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:57881783..57886434 | 10 |
| Wscd1 | gene:RGD | ENCODES a protein that exhibits sulfotransferase activity (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr10:58616509..58645325 | 10 |
| Mybbp1a | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding AND INVOLVED IN cellular response to glucose starvation (ortholog) AND intrinsic apoptotic signaling pathway by p53 class mediator (ortholog) AND negative regulation of transcription DNA-dependent (ortholog) AND FOUND IN nucleus AND NLS-dependent protein nuclear import complex (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr10:59325648..59335604 | 10 |
| Ube2g1 | gene:RGD | ENCODES a protein that exhibits ubiquitin-protein ligase activity AND ubiquitin protein ligase binding (ortholog) AND INVOLVED IN protein K48-linked ubiquitination (ortholog) AND protein K63-linked ubiquitination (ortholog) AND PARTICIPATES IN Alzheimer disease pathway AND altered ubiquitin/proteasome degradation pathway AND ubiquitin/proteasome degradation pathway AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND ammonium chloride AND calcitriol | Chr10:59495501..59576926 | 10 |
| Ankfy1 | gene:RGD | ENCODES a protein that exhibits metal ion binding (inferred) AND FOUND IN endosome membrane (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND flutamide | Chr10:59582425..59654290 | 10 |
| Atp2a3 | gene:RGD | ENCODES a protein that exhibits calcium-transporting ATPase activity AND INVOLVED IN calcium ion transport AND PARTICIPATES IN Alzheimer disease pathway AND calcium signaling pathway AND ASSOCIATED WITH increased systemic arterial systolic blood pressure AND ASSOCIATED WITH Hypertension AND FOUND IN endoplasmic reticulum membrane AND endoplasmic reticulum (ortholog) AND sarcoplasmic reticulum (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND dichlorine | Chr10:59853363..59884087 | 10 |
| Olr1475 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND lead diacetate (ortholog) | Chr10:60446655..60447593 | 10 |
| Olr1498 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr10:61003425..61004363 | 10 |
| Olr1511 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH benzo[a]pyrene (ortholog) AND pregnenolone 16alpha-carbonitrile (ortholog) | Chr10:61419544..61420491 | 10 |
| Olr1513 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride | Chr10:61481889..61482827 | 10 |
| Olr1515 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr10:61516480..61517451 | 10 |
| Olr1516 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND paracetamol (ortholog) | Chr10:61555063..61556034 | 10 |
| Pafah1b1 | gene:RGD | ENCODES a protein that exhibits dynein intermediate chain binding AND protein complex binding AND dynein binding (ortholog) AND INVOLVED IN brain development AND cerebral cortex neuron differentiation AND establishment of centrosome localization AND PARTICIPATES IN Reelin signaling pathway AND altered Reelin signaling pathwayether lipid metabolic pathway AND ASSOCIATED WITH Nervous System Malformations (ortholog) AND FOUND IN axon part AND cytosol AND growth cone AND INTERACTS WITH 17beta-estradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:61955348..62037871 | 10 |
| Sgsm2 | gene:RGD | ENCODES a protein that exhibits Rab GTPase activator activity (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 2-methylcholine (ortholog) | Chr10:62165180..62206440 | 10 |
| Rtn4rl1 | gene:RGD | ENCODES a protein that exhibits receptor activity (ortholog) AND FOUND IN anchored to plasma membrane AND external side of plasma membrane AND membrane raft AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND ammonium chloride | Chr10:62500853..62576593 | 10 |
| Serpinf1 | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred) AND INVOLVED IN aging AND kidney development AND negative regulation of inflammatory response AND ASSOCIATED WITH Alzheimer Disease AND Choroidal Neovascularization AND Diabetes Mellitus Experimental AND FOUND IN extracellular matrix (ortholog) AND extracellular region (ortholog) AND extracellular space (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr10:62713441..62739444 | 10 |
| Serpinf2 | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity AND eukaryotic cell surface binding (ortholog) AND protease binding (ortholog) AND INVOLVED IN negative regulation of fibrinolysis AND response to organic substance AND blood vessel morphogenesis (ortholog) AND PARTICIPATES IN coagulation cascade pathway AND complement system pathway AND ASSOCIATED WITH Hyperlipidemias AND Pancreatitis Acute Necrotizing AND Coronary Artery Disease (ortholog) AND FOUND IN extracellular space AND fibrinogen complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil | Chr10:62748116..62756200 | 10 |
| Rilp | gene:RGD | ENCODES a protein that exhibits Rab GTPase binding (ortholog) AND INVOLVED IN endosome to lysosome transport (ortholog) AND PARTICIPATES IN phagocytosis pathway AND FOUND IN late endosome (ortholog) AND lysosome (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:62831609..62834767 | 10 |
| Pitpna | gene:RGD | ENCODES a protein that exhibits fatty-acyl-CoA binding AND phosphatidylinositol binding AND phosphatidylinositol transporter activity AND INVOLVED IN phospholipid transport AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:62908533..62948856 | 10 |
| Ywhae | gene:RGD | ENCODES a protein that exhibits enzyme binding AND protein complex binding AND histone deacetylase binding (ortholog) AND INVOLVED IN cerebral cortex development (ortholog) AND hippocampus development (ortholog) AND negative regulation of protein dephosphorylation (ortholog) AND PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway AND insulin-like growth factor signaling pathway AND mTOR signaling pathway AND FOUND IN axon part AND kinesin complex AND mitochondrion (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND benzo[a]pyrene | Chr10:63072128..63109833 | 10 |
| Doc2b | gene:RGD | ENCODES a protein that exhibits calcium-dependent phospholipid binding AND syntaxin binding (ortholog) AND INVOLVED IN calcium ion-dependent exocytosis of neurotransmitter AND exocytosis AND positive regulation of calcium ion-dependent exocytosis AND FOUND IN SNARE complex AND plasma membrane AND cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:63115782..63140805 | 10 |
| Dbil5 | gene:RGD | ENCODES a protein that exhibits fatty-acyl-CoA binding (inferred) AND lipid binding (inferred) AND INVOLVED IN spermatogenesis AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND 17alpha-ethynylestradiol (ortholog) | Chr10:63571303..63572315 | 10 |
| LOC100360580 | gene:RGD | ENCODES a protein that exhibits methyltransferase activity (inferred) AND FOUND IN mitochondrion (inferred) AND INTERACTS WITH (S)-nicotine (ortholog) AND 2 4 6-trinitrobenzenesulfonic acid (ortholog) AND benzo[a]pyrene (ortholog) | Chr10:63600163..63600936 | 10 |
| Pipox | gene:RGD | ENCODES a protein that exhibits L-pipecolate oxidase activity (ortholog) AND receptor binding (ortholog) AND sarcosine oxidase activity (ortholog) AND INVOLVED IN L-lysine catabolic process to acetyl-CoA via L-pipecolate (ortholog) AND oxidation-reduction process (ortholog) AND PARTICIPATES IN glycine serine and threonine metabolic pathway AND lysine degradation pathway AND FOUND IN peroxisome (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND cefaloridine | Chr10:63920814..63933307 | 10 |
| Phf12 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II transcription corepressor activity (ortholog) AND phosphatidylinositol binding (ortholog) AND transcription corepressor binding (ortholog) AND INVOLVED IN negative regulation of transcription from RNA polymerase II promoter (ortholog) AND negative regulation of transcription DNA-dependent (ortholog) AND FOUND IN Sin3 complex (ortholog) AND nucleus (ortholog) AND transcriptional repressor complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:64024531..64074458 | 10 |
| Unc119 | gene:RGD | ENCODES a protein that exhibits lipid binding (ortholog) AND INVOLVED IN lipoprotein transport (ortholog) AND FOUND IN centrosome (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND ammonium chloride | Chr10:64285993..64291392 | 10 |
| Pigs | gene:RGD | ENCODES a protein that exhibits GPI-anchor transamidase activity (ortholog) AND INVOLVED IN GPI anchor biosynthetic process (inferred) AND PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway AND FOUND IN endoplasmic reticulum membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr10:64292136..64307281 | 10 |
| Nek8 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND protein serine/threonine kinase activity (inferred) AND FOUND IN primary cilium (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:64458886..64470044 | 10 |
| Slc46a1 | gene:RGD | ENCODES a protein that exhibits folic acid transporter activity (ortholog) AND heme transporter activity (ortholog) AND INVOLVED IN folic acid transport (ortholog) AND heme transport (ortholog) AND FOUND IN apical plasma membrane (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND L-ethionine | Chr10:64576068..64582504 | 10 |
| Taok1 | gene:RGD | ENCODES a protein that exhibits protein kinase activator activity AND protein kinase binding AND protein serine/threonine kinase activity AND INVOLVED IN positive regulation of protein kinase activity AND protein phosphorylation AND regulation of cytoskeleton organization AND PARTICIPATES IN p38 MAPK signaling pathway AND mitogen activated protein kinase signaling pathway AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND calcium atom | Chr10:66503966..66584625 | 10 |
| Blmh | gene:RGD | ENCODES a protein that exhibits peptidase activity (ortholog) AND INVOLVED IN metabolic process (ortholog) AND response to drug (ortholog) AND response to toxin (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:67195276..67238359 | 10 |
| Nxn | gene:RGD | ENCODES a protein that exhibits thioredoxin-disulfide reductase activity (ortholog) AND INVOLVED IN cardiovascular system development (ortholog) AND negative regulation of Wnt receptor signaling pathway (ortholog) AND negative regulation of protein ubiquitination (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND 2 4-dinitrotoluene AND 6-propyl-2-thiouracil | Chr10:67775938..67913018 | 10 |
| Myo1d | gene:RGD | ENCODES a protein that exhibits actin-dependent ATPase activity AND calcium-dependent protein binding AND calmodulin binding AND INVOLVED IN negative regulation of phosphatase activity (ortholog) AND FOUND IN axolemma AND myosin complex AND smooth endoplasmic reticulum AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND amiodarone | Chr10:68720729..68997721 | 10 |
| Ccl12 | gene:RGD | ENCODES a protein that exhibits CCR2 chemokine receptor binding (ortholog) AND INVOLVED IN angiogenesis (ortholog) AND inflammatory response (ortholog) AND monocyte chemotaxis (ortholog) AND PARTICIPATES IN NOD-like receptor signaling pathway AND Plasmodium infection pathway AND Trypanosoma cruzi infection pathway AND FOUND IN extracellular space (inferred) AND INTERACTS WITH C60 fullerene AND edaravone AND quercetin | Chr10:70321036..70322586 | 10 |
| Rffl | gene:RGD | ENCODES a protein that exhibits ligase activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN intracellular protein transport (ortholog) AND PARTICIPATES IN tumor necrosis factor mediated signaling pathway AND FOUND IN cytoplasmic membrane-bounded vesicle (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:71025035..71047280 | 10 |
| Unc45b | gene:RGD | ENCODES a protein that exhibits Hsp90 protein binding (ortholog) AND INVOLVED IN chaperone-mediated protein folding (ortholog) AND FOUND IN cytosol (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND N-nitrosodiethylamine | Chr10:71128525..71156471 | 10 |
| Slfn3 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND INVOLVED IN negative regulation of cell proliferation (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene | Chr10:71277765..71301183 | 10 |
| Ap2b1 | gene:RGD | ENCODES a protein that exhibits clathrin binding AND protein complex binding AND INVOLVED IN clathrin coat assembly AND PARTICIPATES IN Huntington disease pathway AND endocytic pathway AND FOUND IN clathrin coat AND trans-Golgi network AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:71386233..71488000 | 10 |
| Rasl10b | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND GTPase activity (inferred) AND INVOLVED IN positive regulation of peptide hormone secretion (ortholog) AND regulation of systemic arterial blood pressure by atrial natriuretic peptide (ortholog) AND FOUND IN membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:71492903..71503357 | 10 |
| Mmp28 | gene:RGD | ENCODES a protein that exhibits metalloendopeptidase activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN proteolysis (inferred) AND FOUND IN extracellular matrix (inferred) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:71526718..71547699 | 10 |
| Ccl9 | gene:RGD | ENCODES a protein that exhibits chemokine activity (inferred) AND INVOLVED IN immune response (inferred) AND PARTICIPATES IN chemokine mediated signaling pathway AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND cadmium dichloride | Chr10:71645931..71650814 | 10 |
| Ccl6 | gene:RGD | ENCODES a protein that exhibits chemokine activity AND INVOLVED IN cell chemotaxis AND PARTICIPATES IN chemokine mediated signaling pathway AND FOUND IN extracellular space (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:71660623..71665255 | 10 |
| Hnf1b | gene:RGD | ENCODES a protein that exhibits RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity AND core promoter proximal region DNA binding AND protein complex binding AND INVOLVED IN circadian regulation of gene expression AND embryo development AND hepatocyte differentiation AND PARTICIPATES IN forkhead class A signaling pathway AND maturity onset diabetes of the young pathway AND ASSOCIATED WITH Diabetes Mellitus Type 2 (ortholog) AND Kidney Diseases (ortholog) AND Pancreatic Diseases (ortholog) AND FOUND IN nucleus AND transcription factor complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr10:72081091..72187014 | 10 |
| Tada2a | gene:RGD | ENCODES a protein that exhibits histone acetyltransferase activity (ortholog) AND INVOLVED IN histone H3 acetylation (ortholog) AND mitosis (ortholog) AND regulation of histone deacetylation (ortholog) AND FOUND IN Ada2/Gcn5/Ada3 transcription activator complex (ortholog) AND PCAF complex (ortholog) AND mitotic spindle (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) AND 17alpha-ethynylestradiol (ortholog) | Chr10:72365950..72413305 | 10 |
| Acaca | gene:RGD | ENCODES a protein that exhibits ATP binding AND acetyl-CoA carboxylase activity AND biotin binding AND INVOLVED IN acetyl-CoA metabolic process AND fatty acid biosynthetic process AND response to drug AND PARTICIPATES IN fatty acid biosynthetic pathway AND insulin signaling pathway AND propanoate metabolic pathway AND ASSOCIATED WITH Fatty Liver AND Insulin Resistance AND Hyperparathyroidism (ortholog) AND FOUND IN cytosol (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:72483772..72677134 | 10 |
| Pigw | gene:RGD | ENCODES a protein that exhibits transferase activity transferring acyl groups (inferred) AND INVOLVED IN GPI anchor biosynthetic process (inferred) AND PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway AND FOUND IN endoplasmic reticulum membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:73152849..73154357 | 10 |
| Bcas3 | gene:RGD | ASSOCIATED WITH Breast Neoplasms (ortholog) AND FOUND IN cell periphery (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND sodium dichromate | Chr10:73617547..74078190 | 10 |
| breast carcinoma amplified sequence 3 | gene_ont:RGD_Ontology_RDO0005265 | ASSOCIATED WITH Breast Neoplasms (ortholog) AND FOUND IN cell periphery (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2378-tetrachlorodibenzodioxine AND C60 fullerene AND sodium dichromate | Chr10:73617547..74078190 | 10 |
| breast carcinoma amplified sequence 3 | gene_ont:RGD_Ontology_RDO0005309 | ASSOCIATED WITH Breast Neoplasms (ortholog) AND FOUND IN cell periphery (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2378-tetrachlorodibenzodioxine AND C60 fullerene AND sodium dichromate | Chr10:73617547..74078190 | 10 |
| Tbx2 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND sequence-specific DNA binding (ortholog) AND sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN aorta morphogenesis (ortholog) AND atrioventricular canal development (ortholog) AND cardiac muscle tissue development (ortholog) AND FOUND IN nucleus (ortholog) AND transcription factor complex (ortholog) AND INTERACTS WITH C60 fullerene AND D-glucose AND dibutyl phthalate | Chr10:74085203..74092988 | 10 |
| Tbx4 | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND sequence-specific DNA binding transcription factor activity (inferred) AND INVOLVED IN angiogenesis (ortholog) AND embryonic limb morphogenesis (ortholog) AND limb morphogenesis (ortholog) AND ASSOCIATED WITH Joint Diseases (ortholog) AND FOUND IN nucleus (inferred) AND INTERACTS WITH C60 fullerene AND amiodarone (ortholog) AND pirinixic acid (ortholog) | Chr10:74136416..74166080 | 10 |
| Med13 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II transcription cofactor activity (ortholog) AND receptor activity (ortholog) AND thyroid hormone receptor binding (ortholog) AND INVOLVED IN androgen receptor signaling pathway (ortholog) AND intracellular steroid hormone receptor signaling pathway (ortholog) AND positive regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN mediator complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND rotenone AND tributylstannane | Chr10:74498274..74584128 | 10 |
| SS.LEW-(D10Chm224-D10Chm259)/Ayd | congenic:RGD_Rat_Strain | A sub congenic strain derived from the progenitor strain SS.LEW-(<i>D10Chm224-D10Chm6</i>)/Ayd. | Chr10:74705355..75291923 | 10 |
| SS.LEW-(D10Chm224-D10Chm259) | strain_ont:RGD_Ontology_RDO0005134 | A+sub+congenic+strain+derived+from+the+progenitor+strain+SS. LEW-(<i>D10Chm224-D10Chm6</i>)/Ayd. | Chr10:74705355..75291923 | 10 |
| Gdpd1 | gene:RGD | ENCODES a protein that exhibits glycerophosphodiester phosphodiesterase activity (inferred) AND metal ion binding (inferred) AND INVOLVED IN glycerol metabolic process (inferred) AND lipid metabolic process (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 4 6-trinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:75300459..75345043 | 10 |
| Trim37 | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity (ortholog) AND tumor necrosis factor receptor binding (ortholog) AND ubiquitin protein ligase binding (ortholog) AND INVOLVED IN aggresome assembly (ortholog) AND negative regulation of NF-kappaB transcription factor activity (ortholog) AND protein autoubiquitination (ortholog) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND ASSOCIATED WITH Dwarfism (ortholog) AND FOUND IN aggresome (ortholog) AND cytosolic part (ortholog) AND peroxisome (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND indole-3-methanol AND (-)-epigallocatechin 3-gallate (ortholog) | Chr10:75404911..75537072 | 10 |
| Rnf43 | gene:RGD | ENCODES a protein that exhibits frizzled binding (ortholog) AND ubiquitin-protein ligase activity (ortholog) AND INVOLVED IN Wnt receptor catabolic process (ortholog) AND negative regulation of Wnt receptor signaling pathway (ortholog) AND protein ubiquitination (ortholog) AND FOUND IN integral to plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND 17beta-estradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:75957792..76027392 | 10 |
| Bzrap1 | gene:RGD | ENCODES a protein that exhibits benzodiazepine receptor binding (ortholog) AND FOUND IN cytoplasm AND mitochondrion AND INTERACTS WITH C60 fullerene AND bisphenol A AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:76053461..76074635 | 10 |
| SS.LEW-(D10Chm194-D10Chm243)/Ayd | congenic:RGD_Rat_Strain | A sub congenic strain derived from the progenitor strain SS.LEW-(<i>D10Chm224-D10Chm6</i>)/Ayd. | Chr10:76061878..76081753 | 10 |
| SS.LEW-(D10Chm194-D10Chm243) | strain_ont:RGD_Ontology_RDO0005134 | A+sub+congenic+strain+derived+from+the+progenitor+strain+SS. LEW-(<i>D10Chm224-D10Chm6</i>)/Ayd. | Chr10:76061878..76081753 | 10 |
| Lpo | gene:RGD | ENCODES a protein that exhibits heme binding (inferred) AND peroxidase activity (inferred) AND INVOLVED IN response to oxidative stress (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND indole-3-methanol | Chr10:76099137..76118724 | 10 |
| Dynll2 | gene:RGD | ENCODES a protein that exhibits cytoskeletal protein binding AND INVOLVED IN synaptic target recognition AND PARTICIPATES IN vasopressin signaling pathway via receptor type 2 AND FOUND IN cytoplasm AND centrosome (ortholog) AND myosin complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr10:76263883..76271908 | 10 |
| Mrps23 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN intermediate filament cytoskeleton (ortholog) AND mitochondrion (ortholog) AND nuclear membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:76500621..76508379 | 10 |
| Nme2 | gene:RGD | ENCODES a protein that exhibits drug binding AND enzyme binding AND fatty acid binding AND INVOLVED IN CTP biosynthetic process AND GTP biosynthetic process AND UTP biosynthetic process AND PARTICIPATES IN de novo pyrimidine biosynthetic pathway AND purine metabolic pathway AND pyrimidine metabolic pathway AND ASSOCIATED WITH decreased metastatic potential AND ASSOCIATED WITH Neoplasm Metastasis AND Arteriosclerosis (ortholog) AND Endometrial Neoplasms (ortholog) AND FOUND IN intermediate filament AND mitochondrial membrane AND perinuclear region of cytoplasm AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 5-azacytidine AND 6-propyl-2-thiouracil | Chr10:82582766..82588269 | 10 |
| Nme1 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II regulatory region sequence-specific DNA binding AND enzyme binding AND gamma-tubulin binding AND INVOLVED IN cellular response to drug AND cellular response to fatty acid AND cellular response to glucose stimulus AND PARTICIPATES IN E-cadherin signaling pathway AND de novo pyrimidine biosynthetic pathwaypurine metabolic pathway AND ASSOCIATED WITH Cardiomegaly AND Breast Neoplasms (ortholog) AND Carcinoma Pancreatic Ductal (ortholog) AND FOUND IN centrosome AND cytosol AND intermediate filament AND INTERACTS WITH 1 2 4-trimethylbenzene AND 17alpha-ethynylestradiol AND 2 6-dinitrotoluene | Chr10:82591705..82601075 | 10 |
| Spata20 | gene:RGD | ENCODES a protein that exhibits catalytic activity (inferred) AND INVOLVED IN cell differentiation (inferred) AND multicellular organismal development (inferred) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr10:83117661..83124501 | 10 |
| Mrpl27 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr10:83287375..83293135 | 10 |
| Kat7 | gene:RGD | ENCODES a protein that exhibits histone acetyltransferase activity (inferred) AND sequence-specific DNA binding transcription factor activity (inferred) AND transferase activity transferring acyl groups other than amino-acyl groups (inferred) AND INVOLVED IN DNA replication (ortholog) AND histone H3 acetylation (ortholog) AND histone H4-K12 acetylation (ortholog) AND FOUND IN histone acetyltransferase complex (ortholog) AND nucleolus (ortholog) AND nucleoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:83960245..83995124 | 10 |
| Ube2z | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ubiquitin-protein ligase activity (inferred) AND INVOLVED IN apoptotic process (inferred) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 6-propyl-2-thiouracil AND dibutyl phthalate | Chr10:84762405..84781526 | 10 |
| Mrpl10 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (ortholog) AND INVOLVED IN translation (ortholog) AND FOUND IN mitochondrial large ribosomal subunit (ortholog) AND mitochondrion (ortholog) AND ribonucleoprotein complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND (S)-nicotine (ortholog) AND 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine (ortholog) | Chr10:85761934..85770350 | 10 |
| Kpnb1 | gene:RGD | ENCODES a protein that exhibits protein domain specific binding (ortholog) AND protein transporter activity (ortholog) AND INVOLVED IN protein import into nucleus (ortholog) AND ribosomal protein import into nucleus (ortholog) AND PARTICIPATES IN RNA transport pathway AND FOUND IN cytoplasm (ortholog) AND nuclear membrane (ortholog) AND protein complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:85882382..85910805 | 10 |
| Npepps | gene:RGD | ENCODES a protein that exhibits aminopeptidase activity AND INVOLVED IN cellular response to hypoxia (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:85927819..86011826 | 10 |
| Mrpl45 | gene:RGD | ENCODES a protein that exhibits P-P-bond-hydrolysis-driven protein transmembrane transporter activity (inferred) AND INVOLVED IN intracellular protein transport (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ethanol | Chr10:86046541..86058364 | 10 |
| Srcin1 | gene:RGD | ENCODES a protein that exhibits protein domain specific binding AND protein kinase binding (ortholog) AND INVOLVED IN negative regulation of protein secretion AND negative regulation of cell adhesion (ortholog) AND negative regulation of protein tyrosine kinase activity (ortholog) AND FOUND IN actin cytoskeleton AND axon AND dendrite AND INTERACTS WITH C60 fullerene AND ammonium chloride AND lithium atom | Chr10:86263255..86320681 | 10 |
| Mllt6 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr10:86413002..86431124 | 10 |
| Lasp1 | gene:RGD | ENCODES a protein that exhibits ion transmembrane transporter activity AND actin filament binding (ortholog) AND INVOLVED IN ion transmembrane transport AND ion transport AND FOUND IN cortical actin cytoskeleton AND cytoplasm (ortholog) AND focal adhesion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene | Chr10:86552612..86593328 | 10 |
| Rpl19 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (ortholog) AND INVOLVED IN translation (inferred) AND FOUND IN cytosolic large ribosomal subunit (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr10:86788838..86792126 | 10 |
| Neurod2 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND E-box binding (ortholog) AND protein heterodimerization activity (ortholog) AND INVOLVED IN associative learning (ortholog) AND behavioral fear response (ortholog) AND cellular response to calcium ion (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND Delta(9)-tetrahydrocannabinol AND ammonium chloride | Chr10:87097850..87111300 | 10 |
| Med24 | gene:RGD | ENCODES a protein that exhibits histone acetyltransferase activity AND transcription coactivator activity AND RNA polymerase II transcription cofactor activity (ortholog) AND INVOLVED IN histone acetylation AND protein heterooligomerization AND androgen receptor signaling pathway (ortholog) AND FOUND IN nucleus AND mediator complex (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:87477371..87502682 | 10 |
| Nr1d1 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND sequence-specific DNA binding transcription factor activity (ortholog) AND transcription regulatory region DNA binding (ortholog) AND INVOLVED IN cellular response to lipopolysaccharide (ortholog) AND circadian rhythm (ortholog) AND negative regulation of receptor biosynthetic process (ortholog) AND FOUND IN nuclear chromatin (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:87541246..87548186 | 10 |
| Krt13 | gene:RGD | ENCODES a protein that exhibits structural molecule activity (inferred) AND INVOLVED IN cellular response to retinoic acid AND response to radiation AND tongue morphogenesis AND ASSOCIATED WITH Skin Diseases Genetic (ortholog) AND FOUND IN keratin filament (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:89057240..89061150 | 10 |
| Jup | gene:RGD | ENCODES a protein that exhibits protein kinase binding AND structural molecule activity AND alpha-catenin binding (ortholog) AND INVOLVED IN cell-cell adhesion AND protein heterooligomerization AND bundle of His cell to Purkinje myocyte communication (ortholog) AND PARTICIPATES IN E-cadherin signaling pathway AND N-cadherin signaling pathwayacute myeloid leukemia pathway AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Carcinoma Ductal Breast (ortholog) AND Carcinoma Renal Cell (ortholog) AND FOUND IN actin cytoskeleton AND apicolateral plasma membrane AND cell-cell adherens junction AND INTERACTS WITH 2 2' 4 4' 5 5'-hexachlorobiphenyl AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:89307938..89335254 | 10 |
| Nt5c3l | gene:RGD | ENCODES a protein that exhibits 5'-nucleotidase activity (inferred) AND magnesium ion binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN nucleotide metabolic process (inferred) AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:89370969..89385133 | 10 |
| Cnp | gene:RGD | ENCODES a protein that exhibits 2' 3'-cyclic-nucleotide 3'-phosphodiesterase activity AND cyclic nucleotide binding AND INVOLVED IN aging AND forebrain development AND microtubule cytoskeleton organization AND ASSOCIATED WITH Brain Injuries AND Carotid Stenosis AND Encephalomyelitis Autoimmune Experimental AND FOUND IN cell projection AND cytoplasm AND microvillus AND INTERACTS WITH (2 4-dichlorophenoxy)acetic acid AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:89519421..89525978 | 10 |
| Dnajc7 | gene:RGD | ENCODES a protein that exhibits heat shock protein binding (ortholog) AND INVOLVED IN chaperone cofactor-dependent protein refolding (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ferroheme b | Chr10:89527163..89563723 | 10 |
| Hcrt | gene:RGD | ENCODES a protein that exhibits neuropeptide hormone activity AND type 1 hypocretin receptor binding AND type 2 hypocretin receptor binding AND INVOLVED IN eating behavior AND elevation of cytosolic calcium ion concentration AND negative regulation of DNA replication AND PARTICIPATES IN orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1 AND orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2orexin/hypocretin signaling pathway AND ASSOCIATED WITH hyperactivity AND increased eating behavior AND ASSOCIATED WITH Hyperphagia AND Hypertriglyceridemia AND Narcolepsy AND FOUND IN cytoplasm AND secretory granule AND perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:89699633..89700847 | 10 |
| Stat3 | gene:RGD | ENCODES a protein that exhibits CCR5 chemokine receptor binding AND DNA binding AND glucocorticoid receptor binding AND INVOLVED IN acute-phase response AND response to cytokine stimulus AND response to drug AND PARTICIPATES IN Interleukin-10 signaling pathway AND Interleukin-6 signaling pathway AND Jak-Stat signaling pathway AND ASSOCIATED WITH Brain Injuries AND Diabetes Mellitus Experimental AND Non-alcoholic Fatty Liver Disease AND FOUND IN cytoplasm AND nucleus AND plasma membrane (ortholog) AND INTERACTS WITH (+)-alpha-tocopherol AND 1 3-dinitrobenzene AND 1-naphthyl isothiocyanate | Chr10:89821078..89872970 | 10 |
| Atp6v0a1 | gene:RGD | ENCODES a protein that exhibits ATPase binding (ortholog) AND INVOLVED IN ATP hydrolysis coupled proton transport (inferred) AND PARTICIPATES IN Mycobacterium tuberculosis infection pathway AND oxidative phosphorylation pathway AND phagocytosis pathway AND FOUND IN Golgi apparatus (ortholog) AND cytoplasm (ortholog) AND intracellular membrane-bounded organelle (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND C60 fullerene AND ammonium chloride | Chr10:89948286..90072304 | 10 |
| Psmc3ip | gene:RGD | ENCODES a protein that exhibits DBD domain binding AND androgen receptor binding AND estrogen receptor binding AND INVOLVED IN positive regulation of transcription from RNA polymerase II promoter AND FOUND IN nucleus AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:90108909..90112013 | 10 |
| Ezh1 | gene:RGD | ENCODES a protein that exhibits histone methyltransferase activity (H3-K27 specific) (ortholog) AND INVOLVED IN histone H3-K27 methylation (ortholog) AND negative regulation of transcription from RNA polymerase II promoter (ortholog) AND peptidyl-lysine methylation (ortholog) AND FOUND IN ESC/E(Z) complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND benzo[a]pyrene | Chr10:90211249..90237563 | 10 |
| Wnk4 | gene:RGD | ENCODES a protein that exhibits protein serine/threonine kinase activity AND ATP binding (ortholog) AND INVOLVED IN protein phosphorylation AND chloride transport (ortholog) AND intracellular protein kinase cascade (ortholog) AND ASSOCIATED WITH Hypertension (ortholog) AND Pseudohypoaldosteronism (ortholog) AND FOUND IN cytoplasm (ortholog) AND tight junction (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND C60 fullerene AND N-nitrosodiethylamine | Chr10:90289273..90306225 | 10 |
| Psme3 | gene:RGD | ENCODES a protein that exhibits MDM2/MDM4 family protein binding (ortholog) AND endopeptidase activator activity (ortholog) AND p53 binding (ortholog) AND INVOLVED IN positive regulation of endopeptidase activity (ortholog) AND regulation of apoptotic process (ortholog) AND regulation of proteasomal protein catabolic process (ortholog) AND PARTICIPATES IN antigen processing and presentation pathway AND hepatitis C virus infection pathway AND ubiquitin/proteasome degradation pathway AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr10:90343493..90351335 | 10 |
| Aoc3 | gene:RGD | ENCODES a protein that exhibits primary amine oxidase activity AND protein homodimerization activity AND calcium ion binding (ortholog) AND INVOLVED IN aging AND eating behavior AND leukocyte migration involved in inflammatory response AND PARTICIPATES IN beta-alanine metabolic pathway AND glycine serine and threonine metabolic pathway AND phenylalanine metabolic pathway AND ASSOCIATED WITH Aortic Aneurysm AND Arthritis Experimental AND Choroidal Neovascularization AND FOUND IN extracellular space AND intracellular membrane-bounded organelle AND cell surface (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND dibutyl phthalate AND ochratoxin A | Chr10:90357094..90365040 | 10 |
| Rpl27 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN cytosolic large ribosomal subunit (ortholog) AND ribonucleoprotein complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr10:90469811..90473510 | 10 |
| Vat1 | gene:RGD | ENCODES a protein that exhibits nucleotide binding (inferred) AND oxidoreductase activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN negative regulation of mitochondrial fusion (ortholog) AND FOUND IN mitochondrial outer membrane AND INTERACTS WITH 1 1 1-trichloro-2 2-bis(4-hydroxyphenyl)ethane AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr10:90483845..90491463 | 10 |
| Nbr1 | gene:RGD | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog) AND ubiquitin binding (ortholog) AND INVOLVED IN macroautophagy (ortholog) AND negative regulation of osteoblast differentiation (ortholog) AND protein oligomerization (ortholog) AND FOUND IN autophagic vacuole (ortholog) AND cytosol (ortholog) AND late endosome (ortholog) AND INTERACTS WITH C60 fullerene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr10:90573671..90601807 | 10 |
| Etv4 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND INVOLVED IN branching involved in mammary gland duct morphogenesis (ortholog) AND motor neuron axon guidance (ortholog) AND negative regulation of mammary gland epithelial cell proliferation (ortholog) AND FOUND IN intracellular (ortholog) AND nucleolus (ortholog) AND INTERACTS WITH C60 fullerene AND cisplatin AND dibutyl phthalate | Chr10:90808439..90824019 | 10 |
| Dusp3 | gene:RGD | ENCODES a protein that exhibits MAP kinase phosphatase activity (ortholog) AND phosphoprotein phosphatase activity (ortholog) AND protein tyrosine phosphatase activity (ortholog) AND INVOLVED IN in utero embryonic development AND inactivation of MAPK activity (ortholog) AND negative regulation of ERK1 and ERK2 cascade (ortholog) AND PARTICIPATES IN mitogen activated protein kinase signaling pathway AND FOUND IN cytosol (ortholog) AND immunological synapse (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND dibutyl phthalate AND rotenone | Chr10:91031206..91044858 | 10 |
| Mpp3 | gene:RGD | ENCODES a protein that exhibits PDZ domain binding AND FOUND IN cell surface (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND 8-bromo-3' 5'-cyclic AMP (ortholog) | Chr10:91057154..91085728 | 10 |
| Hdac5 | gene:RGD | ENCODES a protein that exhibits histone deacetylase activity (ortholog) AND protein kinase C binding (ortholog) AND repressing transcription factor binding (ortholog) AND INVOLVED IN response to drug AND heart development (ortholog) AND histone deacetylation (ortholog) AND FOUND IN cytoplasm AND nucleus AND Golgi apparatus (ortholog) AND INTERACTS WITH 4-aminopyridine AND C60 fullerene AND ammonium chloride | Chr10:91266512..91277705 | 10 |
| Ubtf | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND INVOLVED IN chromatin silencing at rDNA (ortholog) AND positive regulation of transcription from RNA polymerase I promoter (ortholog) AND ASSOCIATED WITH Cardiomegaly (ortholog) AND FOUND IN nucleus AND nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr10:91385368..91398458 | 10 |
| Slc4a1 | gene:RGD | ENCODES a protein that exhibits actin binding AND protein C-terminus binding AND anion:anion antiporter activity (ortholog) AND INVOLVED IN anion transport (ortholog) AND chloride transport (ortholog) AND ion transmembrane transport (ortholog) AND ASSOCIATED WITH Spherocytosis Hereditary (ortholog) AND FOUND IN Z disc AND basolateral plasma membrane AND cortical cytoskeleton (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND D-penicillamine | Chr10:91454824..91471072 | 10 |
| Fzd2 | gene:RGD | ENCODES a protein that exhibits Wnt-activated receptor activity AND protein heterodimerization activity AND PDZ domain binding (ortholog) AND INVOLVED IN G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger AND Wnt receptor signaling pathway calcium modulating pathway AND cell activation AND PARTICIPATES IN Wnt signaling pathway AND non-canonical Wnt signaling pathwaybasal cell carcinoma pathway AND ASSOCIATED WITH Hypertrophy Left Ventricular AND Myocardial Infarction AND Breast Neoplasms (ortholog) AND FOUND IN plasma membrane AND cytoplasm (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2-nitrotoluene AND C60 fullerene | Chr10:91709222..91711132 | 10 |
| Acbd4 | gene:RGD | ENCODES a protein that exhibits fatty-acyl-CoA binding (inferred) AND lipid binding (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND N-nitrosodiethylamine | Chr10:92276972..92285988 | 10 |
| Fmnl1 | gene:RGD | ENCODES a protein that exhibits GTPase activating protein binding (ortholog) AND Rac GTPase binding (ortholog) AND actin filament binding (ortholog) AND INVOLVED IN actin filament severing (ortholog) AND cellular process (ortholog) AND cortical actin cytoskeleton organization (ortholog) AND FOUND IN cytosol (ortholog) AND phagocytic vesicle (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND chlorpyrifos AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:92343548..92384092 | 10 |
| Arhgap27 | gene:RGD | ENCODES a protein that exhibits GTPase activator activity AND Rac GTPase activator activity AND SH3 domain binding AND INVOLVED IN positive regulation of Cdc42 GTPase activity AND positive regulation of Rac GTPase activity AND receptor-mediated endocytosis AND FOUND IN intracellular AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 4-hydroxynon-2-enal (ortholog) | Chr10:92522546..92551340 | 10 |
| Wnt3 | gene:RGD | ENCODES a protein that exhibits frizzled binding (ortholog) AND protein domain specific binding (ortholog) AND INVOLVED IN Spemann organizer formation at the anterior end of the primitive streak (ortholog) AND anatomical structure formation involved in morphogenesis (ortholog) AND anterior/posterior axis specification (ortholog) AND PARTICIPATES IN Wnt signaling pathway AND canonical Wnt signaling pathwayHedgehog signaling pathway AND ASSOCIATED WITH Ectromelia (ortholog) AND Endometrial Neoplasms (ortholog) AND Mammary Neoplasms Animal (ortholog) AND FOUND IN cytoplasm AND extracellular matrix (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr10:92925605..92969613 | 10 |
| Cdc27 | gene:RGD | ENCODES a protein that exhibits protein phosphatase binding (ortholog) AND INVOLVED IN mitotic metaphase/anaphase transition (ortholog) AND protein K11-linked ubiquitination (ortholog) AND PARTICIPATES IN cell cycle pathway mitotic AND ubiquitin/proteasome degradation pathway AND FOUND IN anaphase-promoting complex (ortholog) AND centrosome (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr10:93678790..93725987 | 10 |
| Mettl2 | gene:RGD | ENCODES a protein that exhibits methyltransferase activity (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr10:94522903..94536622 | 10 |
| Tlk2 | gene:RGD | ENCODES a protein that exhibits ATP binding (ortholog) AND protein serine/threonine kinase activity (ortholog) AND INVOLVED IN cellular response to gamma radiation (ortholog) AND chromosome segregation (ortholog) AND intracellular signal transduction (ortholog) AND FOUND IN intermediate filament (ortholog) AND nucleus (ortholog) AND perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr10:94583881..94675624 | 10 |
| Limd2 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INTERACTS WITH C60 fullerene AND cisplatin AND furan | Chr10:95552509..95554534 | 10 |
| Ftsj3 | gene:RGD | ENCODES a protein that exhibits methyltransferase activity (inferred) AND INVOLVED IN RNA methylation (inferred) AND rRNA processing (inferred) AND FOUND IN nucleolus (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr10:95644169..95650613 | 10 |
| Psmc5 | gene:RGD | ENCODES a protein that exhibits ATPase activity AND TBP-class protein binding AND receptor binding (ortholog) AND INVOLVED IN ATP catabolic process AND negative regulation of transcription DNA-dependent (ortholog) AND proteasomal ubiquitin-dependent protein catabolic process (ortholog) AND PARTICIPATES IN retinoic acid signaling pathway AND ubiquitin/proteasome degradation pathway AND FOUND IN nuclear proteasome complex AND nucleus AND cytoplasm (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 6-dinitrotoluene AND 2-nitrofluorene | Chr10:95650987..95656921 | 10 |
| Polg2 | gene:RGD | ENCODES a protein that exhibits DNA-directed DNA polymerase activity (ortholog) AND identical protein binding (ortholog) AND INVOLVED IN metabolic process (ortholog) AND FOUND IN mitochondrial nucleoid (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:96120205..96130221 | 10 |
| Kpna2 | gene:RGD | ENCODES a protein that exhibits histone deacetylase binding (ortholog) AND nuclear localization sequence binding (ortholog) AND protein transporter activity (ortholog) AND INVOLVED IN regulation of transcription by glucose AND NLS-bearing substrate import into nucleus (ortholog) AND protein import into nucleus (ortholog) AND PARTICIPATES IN influenza A virus infection pathway AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr10:96342214..96352613 | 10 |
| Apoh | gene:RGD | ENCODES a protein that exhibits lipid binding AND eukaryotic cell surface binding (ortholog) AND glycoprotein binding (ortholog) AND INVOLVED IN blood coagulation AND organ regeneration AND triglyceride transport AND PARTICIPATES IN coagulation cascade pathway AND ASSOCIATED WITH Antiphospholipid Syndrome (ortholog) AND Arteriosclerosis (ortholog) AND Diabetes Mellitus (ortholog) AND FOUND IN cell surface (ortholog) AND chylomicron (ortholog) AND extracellular matrix (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND L-ethionine | Chr10:97725088..97739213 | 10 |
| Axin2 | gene:RGD | ENCODES a protein that exhibits beta-catenin binding AND protein kinase binding AND I-SMAD binding (ortholog) AND INVOLVED IN cell death AND cellular response to organic cyclic compound AND negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification AND PARTICIPATES IN altered canonical Wnt signaling pathway AND canonical Wnt signaling pathway AND colorectal cancer pathway AND ASSOCIATED WITH Colorectal Neoplasms (ortholog) AND Metaplasia (ortholog) AND FOUND IN protein complex AND centrosome (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 2' 4 4' 5 5'-hexachlorobiphenyl AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:98294466..98321830 | 10 |
| Abca8a | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATPase activity (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:99477700..99544364 | 10 |
| Map2k6 | gene:RGD | ENCODES a protein that exhibits protein kinase binding (ortholog) AND INVOLVED IN apoptotic process AND positive regulation of apoptotic process AND response to drug AND PARTICIPATES IN p38 MAPK signaling pathway AND FasL mediated signaling pathway AND Interleukin-6 signaling pathway AND ASSOCIATED WITH Cardiomegaly (ortholog) AND Cardiomyopathy Restrictive (ortholog) AND Fibrosis (ortholog) AND INTERACTS WITH (S)-nicotine AND 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine | Chr10:99859684..99974446 | 10 |
| Sstr2 | gene:RGD | ENCODES a protein that exhibits PDZ domain binding AND somatostatin receptor activity AND INVOLVED IN cellular response to estradiol stimulus AND cellular response to glucocorticoid stimulus AND cerebellum development AND ASSOCIATED WITH Brain Injuries AND Diabetes Mellitus Experimental AND Neuroblastoma (ortholog) AND FOUND IN cytoplasm AND plasma membrane AND membrane (ortholog) AND INTERACTS WITH (+)-pilocarpine AND C60 fullerene AND N-nitrosodiethylamine | Chr10:103246880..103254444 | 10 |
| Slc9a3r1 | gene:RGD | ENCODES a protein that exhibits PDZ domain binding (ortholog) AND beta-2 adrenergic receptor binding (ortholog) AND beta-catenin binding (ortholog) AND INVOLVED IN actin cytoskeleton organization (ortholog) AND adenylate cyclase-activating dopamine receptor signaling pathway (ortholog) AND apoptotic process (ortholog) AND PARTICIPATES IN eicosanoids signaling pathway AND platelet-derived growth factor signaling pathway AND FOUND IN apical plasma membrane AND cytoplasm AND microvillus membrane AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:105237637..105254750 | 10 |
| Ict1 | gene:RGD | ENCODES a protein that exhibits aminoacyl-tRNA hydrolase activity (ortholog) AND translation release factor activity codon nonspecific (ortholog) AND INVOLVED IN mitochondrial translational termination (ortholog) AND FOUND IN mitochondrial large ribosomal subunit (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr10:105481865..105488361 | 10 |
| Grb2 | gene:RGD | ENCODES a protein that exhibits epidermal growth factor receptor binding AND insulin receptor substrate binding AND phosphoprotein binding AND INVOLVED IN aging AND protein heterooligomerization AND anatomical structure formation involved in morphogenesis (ortholog) AND PARTICIPATES IN insulin signaling pathway AND insulin-like growth factor signaling pathway AND Interleukin-6 signaling pathway AND FOUND IN protein complex AND Grb2-EGFR complex (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide AND ammonium chloride | Chr10:105722014..105818649 | 10 |
| Llgl2 | gene:RGD | ENCODES a protein that exhibits PDZ domain binding (ortholog) AND INVOLVED IN regulation of establishment or maintenance of cell polarity (ortholog) AND FOUND IN cytoplasm (ortholog) AND intracellular membrane-bounded organelle (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND all-trans-retinoic acid | Chr10:105925312..105960550 | 10 |
| Recql5 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATP-dependent helicase activity (inferred) AND nucleic acid binding (inferred) AND INVOLVED IN DNA recombination (inferred) AND FOUND IN DNA-directed RNA polymerase II holoenzyme (ortholog) AND cytoplasm (ortholog) AND nuclear membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND furan AND 17alpha-ethynylestradiol (ortholog) | Chr10:106000185..106039287 | 10 |
| Acox1 | gene:RGD | ENCODES a protein that exhibits fatty acid binding AND palmitoyl-CoA oxidase activity AND FAD binding (ortholog) AND INVOLVED IN fatty acid beta-oxidation using acyl-CoA oxidase AND fatty acid oxidation (ortholog) AND generation of precursor metabolites and energy (ortholog) AND PARTICIPATES IN alpha-linoleic acid metabolic pathway AND eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma AND fatty acid metabolic pathway AND FOUND IN peroxisome AND cytoplasm (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 1-naphthyl isothiocyanate AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr10:106281977..106319382 | 10 |
| Evpl | gene:RGD | ENCODES a protein that exhibits protein binding bridging (ortholog) AND structural molecule activity (ortholog) AND INVOLVED IN keratinocyte differentiation (ortholog) AND peptide cross-linking (ortholog) AND FOUND IN cornified envelope (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 2 6-di-tert-butyl-4-methylphenol (ortholog) AND L-methionine (ortholog) | Chr10:106336953..106353217 | 10 |
| Prpsap1 | gene:RGD | ENCODES a protein that exhibits enzyme regulator activity AND kinase binding AND INVOLVED IN negative regulation of kinase activity AND FOUND IN protein complex AND ribose phosphate diphosphokinase complex AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil | Chr10:106582381..106604072 | 10 |
| Sphk1 | gene:RGD | ENCODES a protein that exhibits D-erythro-sphingosine kinase activity AND ATP binding (ortholog) AND DNA binding (ortholog) AND INVOLVED IN cellular response to growth factor stimulus AND cellular response to hydrogen peroxide AND cellular response to starvation AND PARTICIPATES IN platelet-derived growth factor signaling pathway AND sphingosine 1-phosphate signaling pathwayFc gamma receptor mediated signaling pathway AND ASSOCIATED WITH Adenocarcinoma AND Glioma AND Diabetes Mellitus Type 2 (ortholog) AND FOUND IN axon AND cytosol AND neuron projection AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr10:106641509..106645579 | 10 |
| St6galnac1 | gene:RGD | ENCODES a protein that exhibits alpha-N-acetylgalactosaminide alpha-2 6-sialyltransferase activity (ortholog) AND INVOLVED IN oligosaccharide biosynthetic process (ortholog) AND PARTICIPATES IN O-linked glycan biosynthetic pathway AND INTERACTS WITH calcitriol (ortholog) AND clofibrate (ortholog) AND lead diacetate (ortholog) | Chr10:106837311..106881619 | 10 |
| Srsf2 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND nucleic acid binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN RNA splicing (inferred) AND mRNA processing (inferred) AND FOUND IN nuclear speck (ortholog) AND nucleus (ortholog) AND spliceosomal complex (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND clofibric acid AND diuron | Chr10:106954365..106956807 | 10 |
| Sept9 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN protein heterooligomerization (ortholog) AND ASSOCIATED WITH Brachial Plexus Neuritis (ortholog) AND FOUND IN actin cytoskeleton (ortholog) AND microtubule (ortholog) AND perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND ammonium chloride | Chr10:107343672..107479964 | 10 |
| Usp36 | gene:RGD | ENCODES a protein that exhibits cysteine-type peptidase activity (inferred) AND ubiquitin thiolesterase activity (inferred) AND INVOLVED IN ubiquitin-dependent protein catabolic process (inferred) AND FOUND IN nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr10:108264874..108296384 | 10 |
| Engase | gene:RGD | ENCODES a protein that exhibits mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity (inferred) AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH C60 fullerene AND benzo[a]pyrene (ortholog) AND copper(2+) sulfate (ortholog) | Chr10:108478622..108491272 | 10 |
| Rbfox3 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND INVOLVED IN regulation of alternative mRNA splicing via spliceosome (ortholog) AND FOUND IN cytoplasm (ortholog) AND intracellular (ortholog) AND neuronal cell body (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND diisopropyl fluorophosphate AND methimazole | Chr10:108492172..108635296 | 10 |
| Slc26a11 | gene:RGD | ENCODES a protein that exhibits anion transmembrane transporter activity (ortholog) AND INVOLVED IN sulfate transport (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND endoplasmic reticulum (ortholog) AND integral to membrane (ortholog) AND INTERACTS WITH 2-methylcholine (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) AND 4-\{[(5 5 8 8-tetramethyl-5 6 7 8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ortholog) | Chr10:108730993..108741761 | 10 |
| Actg1 | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND structural constituent of cytoskeleton (ortholog) AND INVOLVED IN response to calcium ion AND sarcomere organization (ortholog) AND PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway AND dilated cardiomyopathy pathway AND hypertrophic cardimyopathy pathway AND ASSOCIATED WITH Presbycusis (inferred) AND FOUND IN actin cytoskeleton (ortholog) AND filamentous actin (ortholog) AND myofibril (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-di-tert-butyl-4-methylphenol | Chr10:109773489..109776334 | 10 |
| Hgs | gene:RGD | ENCODES a protein that exhibits protein domain specific binding (ortholog) AND INVOLVED IN endosome to lysosome transport AND negative regulation of JAK-STAT cascade (ortholog) AND PARTICIPATES IN autophagy pathway AND vascular endothelial growth factor signaling pathwayendocytic pathway AND FOUND IN cytosol AND membrane AND secretory granule AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND carbonyl sulfide | Chr10:109861289..109869587 | 10 |
| Arhgdia | gene:RGD | ENCODES a protein that exhibits Rho GDP-dissociation inhibitor activity (ortholog) AND INVOLVED IN Rho protein signal transduction (ortholog) AND regulation of catalytic activity (ortholog) AND regulation of protein localization (ortholog) AND PARTICIPATES IN platelet-derived growth factor signaling pathway AND neurotrophic factor signaling pathway AND vasopressin signaling pathway via receptor type 2 AND FOUND IN immunological synapse (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr10:109967771..109971260 | 10 |
| Pcyt2 | gene:RGD | ENCODES a protein that exhibits ethanolamine-phosphate cytidylyltransferase activity AND INVOLVED IN biosynthetic process (inferred) AND phosphatidylethanolamine biosynthetic process (inferred) AND PARTICIPATES IN glycerophospholipid metabolic pathway AND INTERACTS WITH 1 2 4-trimethylbenzene AND C60 fullerene AND ammonium chloride | Chr10:110002023..110009335 | 10 |
| Mafg | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND INVOLVED IN regulation of cellular pH AND adult behavior (ortholog) AND in utero embryonic development (ortholog) AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND cadmium dichloride | Chr10:110019741..110024927 | 10 |
| Uts2r | gene:RGD | ENCODES a protein that exhibits urotensin II receptor activity AND INVOLVED IN elevation of cytosolic calcium ion concentration AND negative regulation of blood pressure AND negative regulation of glomerular filtration AND ASSOCIATED WITH Acute Kidney Injury AND Cardiomyopathies AND Diabetes Mellitus Experimental AND FOUND IN early endosome AND plasma membrane AND recycling endosome AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND ammonium chloride | Chr10:110394782..110395942 | 10 |
| Narf | gene:RGD | ENCODES a protein that exhibits lamin binding (ortholog) AND FOUND IN lamin filament (ortholog) AND nuclear lumen (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr10:110476230..110494161 | 10 |
| Foxk2 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND pregnenolone 16alpha-carbonitrile | Chr10:110499723..110551516 | 10 |
| Prkar1a | gene:RGD | ENCODES a protein that exhibits cAMP binding AND cAMP-dependent protein kinase regulator activity AND ubiquitin protein ligase binding (ortholog) AND INVOLVED IN female meiosis AND negative regulation of meiosis AND regulation of protein kinase activity AND PARTICIPATES IN protein kinase A (PKA) signaling pathway AND apoptotic cell death pathway AND insulin signaling pathway AND ASSOCIATED WITH Cushing Syndrome (ortholog) AND Myxoma (ortholog) AND FOUND IN cAMP-dependent protein kinase complex AND cytoplasm AND neuromuscular junction (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4 6-trinitrotoluene AND D-gluconic acid | Chr10:148642200..148642454 | 10 |
| Gbe1 | gene:RGD | ENCODES a protein that exhibits 1 4-alpha-glucan branching enzyme activity AND carbohydrate binding AND INVOLVED IN glycogen biosynthetic process AND PARTICIPATES IN glycogen biosynthetic pathway AND starch and sucrose metabolic pathway AND ASSOCIATED WITH Glycogen Storage Disease Type IV (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 6-propyl-2-thiouracil AND L-ethionine | Chr11:8720408..8975471 | 10 |
| Cxadr | gene:RGD | ENCODES a protein that exhibits PDZ domain binding (ortholog) AND beta-catenin binding (ortholog) AND cell adhesion molecule binding (ortholog) AND INVOLVED IN AV node cell to bundle of His cell communication (ortholog) AND actin cytoskeleton reorganization (ortholog) AND cardiac muscle fiber development (ortholog) AND PARTICIPATES IN myocarditis pathway AND FOUND IN neuron projection AND tight junction AND acrosomal vesicle (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr11:17193505..17241549 | 10 |
| Grik1 | gene:RGD | ENCODES a protein that exhibits drug binding AND extracellular-glutamate-gated ion channel activity AND glutamate binding AND INVOLVED IN ionotropic glutamate receptor signaling pathway AND negative regulation of synaptic transmission GABAergic AND negative regulation of synaptic transmission glutamatergic AND PARTICIPATES IN long term potentiation AND glutamate signaling pathway AND ASSOCIATED WITH Status Epilepticus AND Epilepsy Absence (ortholog) AND FOUND IN dendrite AND ionotropic glutamate receptor complex AND neuronal cell body AND INTERACTS WITH (+)-pilocarpine AND C60 fullerene AND Delta(9)-tetrahydrocannabinol | Chr11:27703874..28106450 | 10 |
| Cldn8 | gene:RGD | ENCODES a protein that exhibits structural molecule activity (inferred) AND PARTICIPATES IN hepatitis C virus infection pathway AND FOUND IN endoplasmic reticulum (ortholog) AND plasma membrane (ortholog) AND tight junction (ortholog) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND 17beta-estradiol (ortholog) | Chr11:28419612..28421861 | 10 |
| Gart | gene:RGD | ENCODES a protein that exhibits phosphoribosylamine-glycine ligase activity AND phosphoribosylformylglycinamidine cyclo-ligase activity AND phosphoribosylglycinamide formyltransferase activity AND INVOLVED IN brainstem development AND cerebellum development AND cerebral cortex development AND PARTICIPATES IN de novo purine biosynthetic pathway AND folate mediated one-carbon metabolic pathway AND pathway of folate cycle/metabolism AND ASSOCIATED WITH Down Syndrome (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:31594859..31620110 | 10 |
| Kcne2 | gene:RGD | ENCODES a protein that exhibits potassium channel regulator activity AND voltage-gated potassium channel activity AND INVOLVED IN cellular protein localization (ortholog) AND potassium ion transmembrane transport (ortholog) AND regulation of ventricular cardiac muscle cell action potential (ortholog) AND ASSOCIATED WITH Atrial Fibrillation (ortholog) AND Long QT Syndrome (ortholog) AND FOUND IN integral to membrane AND voltage-gated potassium channel complex AND lysosome (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND ammonium chloride AND methimazole | Chr11:32277711..32290828 | 10 |
| Cbr1 | gene:RGD | ENCODES a protein that exhibits carbonyl reductase (NADPH) activity AND oxidoreductase activity acting on NADH or NADPH quinone or similar compound as acceptor (ortholog) AND INVOLVED IN ovulation from ovarian follicle AND phylloquinone catabolic process AND response to gonadotropin stimulus AND PARTICIPATES IN arachidonic acid metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND FOUND IN intracellular membrane-bounded organelle AND microvillus AND nucleus AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:33787957..33790320 | 10 |
| Hlcs | gene:RGD | ENCODES a protein that exhibits biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity AND protein homodimerization activity AND biotin binding (ortholog) AND INVOLVED IN response to biotin AND cell proliferation (ortholog) AND histone biotinylation (ortholog) AND PARTICIPATES IN biotin metabolic pathway AND FOUND IN chromatin (ortholog) AND cytoplasm (ortholog) AND cytosol (ortholog) AND INTERACTS WITH C60 fullerene AND indole-3-methanol AND lead diacetate | Chr11:34382010..34539032 | 10 |
| Pigp | gene:RGD | ENCODES a protein that exhibits phosphatidylinositol N-acetylglucosaminyltransferase activity (ortholog) AND INVOLVED IN GPI anchor biosynthetic process (ortholog) AND PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway AND FOUND IN endoplasmic reticulum (ortholog) AND glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND N-nitrosodiethylamine | Chr11:34610876..34617001 | 10 |
| Dyrk1a | gene:RGD | ENCODES a protein that exhibits protein serine/threonine kinase activity AND protein tyrosine kinase activity AND non-membrane spanning protein tyrosine kinase activity (ortholog) AND INVOLVED IN peptidyl-tyrosine phosphorylation AND protein autophosphorylation AND protein phosphorylation AND ASSOCIATED WITH Intellectual Disability (inferred) AND FOUND IN nuclear speck AND nucleolus AND nucleus AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr11:34879733..34970998 | 10 |
| Hmgn1 | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND INVOLVED IN chromatin organization (ortholog) AND post-embryonic camera-type eye morphogenesis (ortholog) AND pyrimidine dimer repair by nucleotide-excision repair (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:36429800..36435719 | 10 |
| Olr1535 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr11:41915692..41916621 | 10 |
| Olr1557 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr11:42319526..42320455 | 10 |
| Gpr15 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH C60 fullerene AND diarsenic trioxide (ortholog) AND pirinixic acid (ortholog) | Chr11:42709928..42712013 | 10 |
| Cpox | gene:RGD | ENCODES a protein that exhibits coproporphyrinogen oxidase activity AND identical protein binding AND protein homodimerization activity (ortholog) AND INVOLVED IN heme biosynthetic process AND protoporphyrinogen IX biosynthetic process AND response to arsenic-containing substance AND PARTICIPATES IN heme biosynthetic pathway AND porphyrin and chlorophyll metabolic pathway AND ASSOCIATED WITH Arthritis Experimental AND Porphyrias Hepatic AND Liver Diseases (ortholog) AND FOUND IN mitochondrial inner membrane AND mitochondrial intermembrane space AND mitochondrion AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 17beta-estradiol (ortholog) | Chr11:42748703..42758686 | 10 |
| Tfg | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND signal transducer activity (ortholog) AND INVOLVED IN positive regulation of I-kappaB kinase/NF-kappaB cascade (ortholog) AND signal transduction (ortholog) AND PARTICIPATES IN thyroid cancer pathway AND INTERACTS WITH 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND acetylsalicylic acid (ortholog) | Chr11:44826798..44853093 | 10 |
| Cblb | gene:RGD | ENCODES a protein that exhibits protein kinase binding AND INVOLVED IN response to gravity AND response to hormone stimulus AND signal transduction AND PARTICIPATES IN Jak-Stat signaling pathway AND T cell receptor signaling pathway AND chronic myeloid leukemia pathway AND ASSOCIATED WITH Arthritis Experimental AND Diabetes Mellitus Type 1 AND Insulin Resistance (ortholog) AND FOUND IN membrane raft AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:49690402..49856762 | 10 |
| Retnla | gene:RGD | ENCODES a protein that exhibits hormone activity (inferred) AND FOUND IN extracellular region (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND quartz | Chr11:53205246..53206745 | 10 |
| Atp6v1a | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND hydrogen ion transporting ATP synthase activity rotational mechanism (inferred) AND proton-transporting ATPase activity rotational mechanism (inferred) AND INVOLVED IN ATP hydrolysis coupled proton transport (inferred) AND PARTICIPATES IN oxidative phosphorylation pathway AND phagocytosis pathway AND rheumatoid arthritis pathway AND FOUND IN apical plasma membrane (ortholog) AND cytosol (ortholog) AND microvillus (ortholog) AND INTERACTS WITH 2 2 2-tetramine AND 6-propyl-2-thiouracil AND L-ethionine | Chr11:58127307..58180225 | 10 |
| Drd3 | gene:RGD | ENCODES a protein that exhibits dopamine binding AND dopamine receptor activity AND dopamine receptor activity coupled via Gi/Go AND INVOLVED IN G-protein coupled receptor internalization AND G-protein coupled receptor signaling pathway AND acid secretion AND PARTICIPATES IN dopamine signaling pathway AND ASSOCIATED WITH circling AND ASSOCIATED WITH Hypertension AND Parkinsonian Disorders AND Seizures AND FOUND IN apical part of cell AND cell projection AND endocytic vesicle AND INTERACTS WITH (S)-colchicine AND 17beta-estradiol AND C60 fullerene | Chr11:58446901..58520589 | 10 |
| Zbtb20 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription (ortholog) AND INVOLVED IN negative regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr11:58662837..59399213 | 10 |
| Arhgap31 | gene:RGD | ENCODES a protein that exhibits GTPase activator activity (ortholog) AND SH3 domain binding (ortholog) AND INVOLVED IN small GTPase mediated signal transduction (ortholog) AND FOUND IN lamellipodium (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND L-methionine (ortholog) | Chr11:63814916..63929011 | 10 |
| Cox17 | gene:RGD | ENCODES a protein that exhibits copper ion binding (ortholog) AND enzyme activator activity (ortholog) AND INVOLVED IN brain development AND heart development AND positive regulation of catalytic activity (ortholog) AND PARTICIPATES IN oxidative phosphorylation pathway AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr11:64183573..64185985 | 10 |
| Gpr156 | gene:RGD | ENCODES a protein that exhibits G-protein coupled GABA receptor activity (inferred) AND FOUND IN plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr11:64506980..64571771 | 10 |
| Hgd | gene:RGD | ENCODES a protein that exhibits homogentisate 1 2-dioxygenase activity (ortholog) AND INVOLVED IN cellular amino acid metabolic process (ortholog) AND PARTICIPATES IN tyrosine metabolic pathway AND ASSOCIATED WITH Alkaptonuria (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND L-ethionine | Chr11:64876269..64928243 | 10 |
| Rabl3 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN small GTPase mediated signal transduction (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND caffeine AND methylmercury chloride | Chr11:64943199..64972157 | 10 |
| Parp9 | gene:RGD | ENCODES a protein that exhibits NAD+ ADP-ribosyltransferase activity (inferred) AND INVOLVED IN regulation of response to interferon-gamma (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr11:66615587..66648294 | 10 |
| Ropn1 | gene:RGD | ENCODES a protein that exhibits cAMP-dependent protein kinase regulator activity (inferred) AND INVOLVED IN signal transduction (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:67915535..67944757 | 10 |
| Kalrn | gene:RGD | ENCODES a protein that exhibits enzyme binding AND INVOLVED IN axonogenesis AND intracellular signal transduction AND nervous system development AND PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis AND ASSOCIATED WITH Huntington Disease (inferred) AND FOUND IN neuron projection AND neuronal cell body AND perinuclear region of cytoplasm AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione | Chr11:68124348..68611336 | 10 |
| Umps | gene:RGD | ENCODES a protein that exhibits orotate phosphoribosyltransferase activity AND orotidine-5'-phosphate decarboxylase activity AND INVOLVED IN UMP biosynthetic process AND cellular response to drug AND female pregnancy AND PARTICIPATES IN de novo pyrimidine biosynthetic pathway AND pyrimidine metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Purine-Pyrimidine Metabolism Inborn Errors (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr11:68619835..68630244 | 10 |
| Slc12a8 | gene:RGD | ENCODES a protein that exhibits symporter activity (inferred) AND INVOLVED IN potassium ion transport (inferred) AND transmembrane transport (inferred) AND FOUND IN integral to membrane (inferred) AND membrane (inferred) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND ammonium chloride | Chr11:68934104..69087168 | 10 |
| Zfp148 | gene:RGD | ENCODES a protein that exhibits double-stranded DNA binding AND transcription regulatory region sequence-specific DNA binding AND DNA binding (ortholog) AND INVOLVED IN negative regulation of transcription from RNA polymerase II promoter AND protein complex assembly AND gamete generation (ortholog) AND FOUND IN nucleus AND Golgi apparatus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr11:69103680..69207360 | 10 |
| Muc4 | gene:RGD | ENCODES a protein that exhibits ErbB-2 class receptor binding AND protein complex binding AND INVOLVED IN cellular response to insulin stimulus AND cellular response to transforming growth factor beta stimulus AND digestive tract development AND ASSOCIATED WITH Cholangiocarcinoma AND Nematode Infections AND Neoplasm Metastasis AND FOUND IN apical plasma membrane AND cytoplasm AND endoplasmic reticulum AND INTERACTS WITH 17alpha-ethynylestradiol AND 17beta-estradiol AND C60 fullerene | Chr11:69830276..69858366 | 10 |
| Tfrc | gene:RGD | ENCODES a protein that exhibits Hsp70 protein binding AND chaperone binding AND transferrin receptor activity AND INVOLVED IN acute-phase response AND aging AND response to copper ion AND PARTICIPATES IN forkhead class A signaling pathway AND hypoxia inducible factor pathwayendocytic pathway AND ASSOCIATED WITH Acute-Phase Reaction AND Carcinoma Hepatocellular AND Muscular Atrophy AND FOUND IN cell surface AND extracellular vesicular exosome AND mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 2-acetamidofluorene | Chr11:69976258..69998098 | 10 |
| Bdh1 | gene:RGD | ENCODES a protein that exhibits 3-hydroxybutyrate dehydrogenase activity AND phospholipid binding AND INVOLVED IN adipose tissue development AND brain development AND liver development AND PARTICIPATES IN forkhead class A signaling pathway AND ketone bodies metabolic pathwaybutanoate metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Hyperthyroidism AND FOUND IN mitochondrial inner membrane AND mitochondrion (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr11:71130561..71165695 | 10 |
| Lsg1 | gene:RGD | ENCODES a protein that exhibits GTP binding (ortholog) AND INVOLVED IN nuclear export (ortholog) AND PARTICIPATES IN ribosome biogenesis pathway AND FOUND IN Cajal body (ortholog) AND cytoplasm (ortholog) AND endoplasmic reticulum (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND rotenone | Chr11:72026815..72051401 | 10 |
| Hes1 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding AND DNA binding (ortholog) AND N-box binding (ortholog) AND INVOLVED IN forebrain radial glial cell differentiation AND negative regulation of forebrain neuron differentiation AND negative regulation of transcription from RNA polymerase II promoter AND PARTICIPATES IN Notch signaling pathway AND maturity onset diabetes of the young pathway AND FOUND IN cytoplasm (ortholog) AND intracellular (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione | Chr11:72603482..72605673 | 10 |
| Opa1 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND GTPase activity (inferred) AND INVOLVED IN visual perception AND cellular senescence (ortholog) AND inner mitochondrial membrane organization (ortholog) AND FOUND IN dendrite (ortholog) AND mitochondrial crista (ortholog) AND mitochondrial inner membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND ammonium chloride | Chr11:73005470..73058136 | 10 |
| Il1rap | gene:RGD | ENCODES a protein that exhibits interleukin-1 receptor binding AND interleukin-1 receptor activity (ortholog) AND signal transducer activity (ortholog) AND INVOLVED IN cytokine-mediated signaling pathway (ortholog) AND interleukin-2 biosynthetic process (ortholog) AND PARTICIPATES IN interleukin-1 signaling pathway AND apoptotic cell death pathway AND cytokine mediated signaling pathway AND FOUND IN cytoplasm AND protein complex AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr11:76092252..76222576 | 10 |
| Cldn1 | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND INVOLVED IN calcium-independent cell-cell adhesion (ortholog) AND cell-cell junction organization (ortholog) AND PARTICIPATES IN hepatitis C virus infection pathway AND FOUND IN lateral plasma membrane AND tight junction AND apical plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:76473654..76488809 | 10 |
| St6gal1 | gene:RGD | ENCODES a protein that exhibits beta-galactoside alpha-2 6-sialyltransferase activity (ortholog) AND sialyltransferase activity (ortholog) AND INVOLVED IN metabolic process (ortholog) AND protein glycosylation (ortholog) AND PARTICIPATES IN N-linked glycan biosynthetic pathway AND O-linked glycan biosynthetic pathway AND FOUND IN Golgi cisterna membrane (inferred) AND extracellular region (inferred) AND integral to Golgi membrane (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene | Chr11:79723269..79765645 | 10 |
| Hrg | gene:RGD | ENCODES a protein that exhibits cell surface binding (ortholog) AND heme binding (ortholog) AND heparan sulfate proteoglycan binding (ortholog) AND INVOLVED IN defense response to fungus (ortholog) AND negative regulation of angiogenesis (ortholog) AND negative regulation of blood vessel endothelial cell migration (ortholog) AND ASSOCIATED WITH Thrombosis (ortholog) AND FOUND IN extracellular region (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND cefaloridine | Chr11:80248578..80264179 | 10 |
| Ahsg | gene:RGD | ENCODES a protein that exhibits receptor signaling protein tyrosine kinase inhibitor activity AND INVOLVED IN cellular response to insulin stimulus AND cerebral cortex development AND male gonad development AND PARTICIPATES IN Bone morphogenetic proteins signaling pathway AND ASSOCIATED WITH Coronary Artery Disease (ortholog) AND Diabetes Mellitus Type 2 (ortholog) AND Diabetes Gestational (ortholog) AND FOUND IN extracellular matrix AND extracellular space AND protein complex AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND 9-cis-retinoic acid | Chr11:80330615..80336658 | 10 |
| Etv5 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding transcription factor activity (ortholog) AND transcription regulatory region DNA binding (ortholog) AND INVOLVED IN male germ-line stem cell division AND positive regulation of glial cell proliferation AND positive regulation of neuron differentiation AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND C60 fullerene AND astemizole | Chr11:80846286..80904013 | 10 |
| Tra2b | gene:RGD | ENCODES a protein that exhibits mRNA binding (ortholog) AND INVOLVED IN response to reactive oxygen species AND mRNA splicing via spliceosome (ortholog) AND positive regulation of mRNA splicing via spliceosome (ortholog) AND PARTICIPATES IN spliceosome pathway AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 3H-1 2-dithiole-3-thione AND C60 fullerene | Chr11:81026729..81044936 | 10 |
| Ephb3 | gene:RGD | ENCODES a protein that exhibits axon guidance receptor activity (ortholog) AND ephrin receptor activity (ortholog) AND INVOLVED IN angiogenesis (ortholog) AND axon guidance (ortholog) AND axonal fasciculation (ortholog) AND PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis AND FOUND IN integral to plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND cocaine AND lead diacetate | Chr11:82027632..82046332 | 10 |
| Chrd | gene:RGD | ENCODES a protein that exhibits heparin binding (ortholog) AND syndecan binding (ortholog) AND INVOLVED IN BMP signaling pathway involved in spinal cord dorsal/ventral patterning (ortholog) AND central nervous system development (ortholog) AND dorsal/ventral pattern formation (ortholog) AND PARTICIPATES IN Bone morphogenetic proteins signaling pathway AND transforming growth factor-beta superfamily mediated signaling pathway AND FOUND IN extracellular space (ortholog) AND INTERACTS WITH 1-naphthyl isothiocyanate AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:82401701..82410401 | 10 |
| Psmd2 | gene:RGD | ENCODES a protein that exhibits enzyme regulator activity (inferred) AND INVOLVED IN regulation of protein catabolic process (inferred) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND FOUND IN proteasome accessory complex (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND bis(2-ethylhexyl) phthalate AND piperonyl butoxide | Chr11:82478177..82488804 | 10 |
| Alg3 | gene:RGD | ENCODES a protein that exhibits alpha-1 3-mannosyltransferase activity (ortholog) AND PARTICIPATES IN N-linked glycan biosynthetic pathway AND FOUND IN endoplasmic reticulum membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND phenobarbital AND 17alpha-ethynylestradiol (ortholog) | Chr11:82507540..82535341 | 10 |
| Abcf3 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATPase activity (inferred) AND INVOLVED IN defense response to virus (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:82570495..82582228 | 10 |
| Ap2m1 | gene:RGD | ENCODES a protein that exhibits lipid binding (inferred) AND INVOLVED IN intracellular protein transport (inferred) AND vesicle-mediated transport (inferred) AND PARTICIPATES IN Arf family mediated signaling pathway AND Huntington disease pathway AND endocytic pathway AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND amiodarone | Chr11:82585474..82591832 | 10 |
| Parl | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase activity (inferred) AND INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway (ortholog) AND negative regulation of release of cytochrome c from mitochondria (ortholog) AND FOUND IN mitochondrial inner membrane (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr11:82836666..82864977 | 10 |
| Gp1bb | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN blood coagulation (inferred) AND cell adhesion (inferred) AND cell cycle (inferred) AND PARTICIPATES IN platelet aggregation pathway AND cell-extracellular matrix signaling pathway AND FOUND IN integral to membrane (inferred) AND septin complex (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND cisplatin | Chr11:84369795..84370972 | 10 |
| Txnrd2 | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity AND thioredoxin-disulfide reductase activity AND INVOLVED IN response to drug AND response to hyperoxia AND response to selenium ion AND PARTICIPATES IN pyrimidine metabolic pathway AND selenoamino acid metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Reperfusion Injury AND FOUND IN axon AND cytoplasm AND dendrite AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND auranofin | Chr11:84513361..84561673 | 10 |
| Trmt2a | gene:RGD | ENCODES a protein that exhibits RNA methyltransferase activity (inferred) AND nucleic acid binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN RNA processing (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr11:84731490..84736099 | 10 |
| Slc25a1 | gene:RGD | ENCODES a protein that exhibits citrate transmembrane transporter activity (inferred) AND INVOLVED IN mitochondrial citrate transport (inferred) AND FOUND IN mitochondrial inner membrane (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND C60 fullerene AND ammonium chloride | Chr11:85043902..85046919 | 10 |
| Scarf2 | gene:RGD | ENCODES a protein that exhibits scavenger receptor activity (ortholog) AND INVOLVED IN heterophilic cell-cell adhesion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND methimazole | Chr11:85164352..85175734 | 10 |
| Pi4ka | gene:RGD | ENCODES a protein that exhibits 1-phosphatidylinositol 4-kinase activity AND PARTICIPATES IN inositol phosphate metabolic pathway AND phosphatidylinositol 3-kinase signaling pathway AND FOUND IN Golgi-associated vesicle membrane AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr11:85610281..85726603 | 10 |
| Ppm1f | gene:RGD | ENCODES a protein that exhibits calmodulin-dependent protein phosphatase activity (ortholog) AND phosphatase activity (ortholog) AND protein serine/threonine phosphatase activity (ortholog) AND INVOLVED IN positive regulation of cysteine-type endopeptidase activity involved in apoptotic process AND cellular response to drug (ortholog) AND intrinsic apoptotic signaling pathway (ortholog) AND FOUND IN cytosol AND perinuclear region of cytoplasm AND protein complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND ammonium chloride | Chr11:86086968..86114278 | 10 |
| Top3b | gene:RGD | ENCODES a protein that exhibits DNA topoisomerase type I activity (inferred) AND INVOLVED IN chromosome segregation (ortholog) AND PARTICIPATES IN homologous recombination pathway of double-strand break repair AND FOUND IN condensed chromosome (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND (S)-amphetamine (ortholog) | Chr11:86116936..86145314 | 10 |
| Pkp2 | gene:RGD | ENCODES a protein that exhibits intermediate filament binding (ortholog) AND protein complex scaffold (ortholog) AND protein kinase C binding (ortholog) AND INVOLVED IN adherens junction maintenance AND gap junction assembly AND lipid homeostasis AND PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway AND ASSOCIATED WITH Arrhythmogenic Right Ventricular Dysplasia (ortholog) AND FOUND IN adherens junction AND intercalated disc AND cell-cell junction (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr11:86553493..86584425 | 10 |
| Dnm1l | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND ubiquitin protein ligase binding (ortholog) AND INVOLVED IN dynamin polymerization involved in mitochondrial fission (ortholog) AND membrane fission involved in mitochondrial fission (ortholog) AND mitochondrial fission (ortholog) AND PARTICIPATES IN Fc gamma receptor mediated signaling pathway AND endocytic pathway AND FOUND IN cytosol AND intracellular membrane-bounded organelle AND mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr11:86617236..86665861 | 10 |
| Ube2v2 | gene:RGD | ENCODES a protein that exhibits acid-amino acid ligase activity (inferred) AND INVOLVED IN negative regulation of neuron apoptotic process AND positive regulation of DNA repair AND positive regulation of neuron projection development AND FOUND IN UBC13-MMS2 complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND PD123319 | Chr11:87215842..87249726 | 10 |
| QTL:Pia4 | QTL:RGD | COMP day 35 (LOD 6.1) | Chr12:568621..45568621 | 10 |
| Vom2r60 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride | Chr12:1141669..1252998 | 10 |
| Map2k7 | gene:RGD | ENCODES a protein that exhibits ATP binding AND JUN kinase kinase activity AND MAP kinase kinase activity AND INVOLVED IN JNK cascade AND activation of JUN kinase activity AND positive regulation of neuron apoptotic process AND PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway AND FasL mediated signaling pathway AND Reelin signaling pathway AND ASSOCIATED WITH Prostatic Intraepithelial Neoplasia (ortholog) AND Prostatic Neoplasms (ortholog) AND FOUND IN cytosol AND nucleus AND cytoplasm (ortholog) AND INTERACTS WITH cadmium dichloride AND (S)-nicotine (ortholog) AND 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine (ortholog) | Chr12:1545407..1552353 | 10 |
| Arhgef18 | gene:RGD | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog) AND INVOLVED IN actin cytoskeleton organization (ortholog) AND regulation of cell shape (ortholog) AND small GTPase mediated signal transduction (ortholog) AND FOUND IN apical part of cell (ortholog) AND cytoplasm (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND cadmium dichloride | Chr12:2712198..2855137 | 10 |
| Pomp | gene:RGD | ENCODES a protein that exhibits ion channel activity (inferred) AND INVOLVED IN proteasome assembly (ortholog) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-di-tert-butyl-4-methylphenol | Chr12:7719721..7732544 | 10 |
| Pan3 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND protein kinase activity (inferred) AND INVOLVED IN deadenylation-dependent decapping of nuclear-transcribed mRNA (ortholog) AND positive regulation of cytoplasmic mRNA processing body assembly (ortholog) AND protein targeting (ortholog) AND PARTICIPATES IN RNA degradation pathway AND FOUND IN centrosome (ortholog) AND cytoplasmic mRNA processing body (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND aflatoxin B1 (ortholog) | Chr12:8046162..8165081 | 10 |
| Flt3 | gene:RGD | ENCODES a protein that exhibits cytokine receptor activity AND glucocorticoid receptor binding AND phosphatidylinositol 3-kinase binding AND INVOLVED IN B cell differentiation AND cellular response to cytokine stimulus AND cellular response to glucocorticoid stimulus AND PARTICIPATES IN acute myeloid leukemia pathway AND cytokine mediated signaling pathway AND ASSOCIATED WITH Arthritis Experimental AND Leukemia Myeloid Acute (ortholog) AND Lymphatic Metastasis (ortholog) AND FOUND IN cell surface AND cytoplasm AND cytosol AND INTERACTS WITH 2-acetamidofluorene AND 6-propyl-2-thiouracil AND ammonium chloride | Chr12:8193629..8268682 | 10 |
| Lnx2 | gene:RGD | ENCODES a protein that exhibits PDZ domain binding (ortholog) AND INVOLVED IN protein homooligomerization (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND furan | Chr12:8359540..8420393 | 10 |
| Gsx1 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog) AND INVOLVED IN adenohypophysis development (ortholog) AND hypothalamus development (ortholog) AND neuron fate commitment (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND paracetamol (ortholog) | Chr12:8551150..8552445 | 10 |
| Cyp3a2 | gene:RGD | ENCODES a protein that exhibits demethylase activity AND monooxygenase activity AND testosterone 6-beta-hydroxylase activity AND INVOLVED IN drug metabolic process AND oxidative demethylation AND PARTICIPATES IN tamoxifen pharmacokinetics pathway AND linoleic acid metabolic pathway AND phase I biotransformation pathway via cytochrome P450 AND ASSOCIATED WITH Anxiety Disorders AND Inflammation (ortholog) AND Subarachnoid Hemorrhage (ortholog) AND FOUND IN endoplasmic reticulum membrane (inferred) AND INTERACTS WITH 1 2-dichloroethene AND 1 2-dilauroyl-sn-glycero-3-phosphocholine AND 17alpha-ethynylestradiol | Chr12:9517016..9541000 | 10 |
| Cyp3a23/3a1 | gene:RGD | ENCODES a protein that exhibits demethylase activity AND testosterone 6-beta-hydroxylase activity AND INVOLVED IN aging AND drug metabolic process AND oxidative demethylation AND PARTICIPATES IN tamoxifen pharmacokinetics pathway AND linoleic acid metabolic pathway AND phase I biotransformation pathway via cytochrome P450 AND ASSOCIATED WITH Depressive Disorder AND Inflammation AND FOUND IN endoplasmic reticulum membrane AND intracellular membrane-bounded organelle AND INTERACTS WITH 1-naphthyl isothiocyanate AND 2-acetamidofluorene AND 3H-1 2-dithiole-3-thione | Chr12:9567120..9595974 | 10 |
| Bhlha15 | gene:RGD | ENCODES a protein that exhibits DNA binding AND protein homodimerization activity (ortholog) AND INVOLVED IN G-protein coupled receptor signaling pathway (ortholog) AND Golgi organization (ortholog) AND calcium-mediated signaling (ortholog) AND PARTICIPATES IN maturity onset diabetes of the young pathway AND FOUND IN nucleus AND INTERACTS WITH 2 4 6-trinitrotoluene AND ammonium chloride AND coumarin | Chr12:10747865..10752041 | 10 |
| Pms2 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND single base insertion or deletion binding (inferred) AND INVOLVED IN response to drug AND PARTICIPATES IN altered mismatch repair pathway AND colorectal cancer pathway AND mismatch repair pathway AND ASSOCIATED WITH Brain Neoplasms (ortholog) AND Breast Neoplasms (ortholog) AND Colonic Neoplasms (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND O-methyleugenol AND cyclophosphamide | Chr12:11004507..11028754 | 10 |
| Rac1 | gene:RGD | ENCODES a protein that exhibits GTP binding AND GTPase activity AND Rab GTPase binding AND INVOLVED IN GTP catabolic process AND actin cytoskeleton organization AND actin filament organization AND PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway AND Arf family mediated signaling pathway AND E-cadherin signaling pathway AND ASSOCIATED WITH Heart Failure AND Hypertrophy Left Ventricular AND Cardiomegaly (ortholog) AND FOUND IN Golgi membrane AND cytoplasm AND cytoplasmic vesicle AND INTERACTS WITH 11-deoxycorticosterone AND 2 2'-iminobis[1-(6-fluoro-3 4-dihydro-2H-chromen-2-yl)ethanol] AND 2 4-dinitrotoluene | Chr12:11380314..11400531 | 10 |
| Zdhhc4 | gene:RGD | ENCODES a protein that exhibits transferase activity transferring acyl groups (inferred) AND zinc ion binding (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr12:11594931..11605771 | 10 |
| Wipi2 | gene:RGD | ENCODES a protein that exhibits phosphatidylinositol-3 5-bisphosphate binding (ortholog) AND phosphatidylinositol-3-phosphate binding (ortholog) AND INVOLVED IN autophagic vacuole assembly (ortholog) AND FOUND IN autophagic vacuole (ortholog) AND cytoplasm (ortholog) AND cytosol (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cadmium dichloride | Chr12:12306563..12334993 | 10 |
| Gna12 | gene:RGD | ENCODES a protein that exhibits D5 dopamine receptor binding AND INVOLVED IN response to drug AND Rho protein signal transduction (ortholog) AND cell differentiation (ortholog) AND PARTICIPATES IN eicosanoids signaling pathway AND endothelin signaling pathway AND sphingosine 1-phosphate signaling pathway AND FOUND IN brush border membrane AND INTERACTS WITH 3H-1 2-dithiole-3-thione AND C60 fullerene AND ammonium chloride | Chr12:14275708..14354843 | 10 |
| Snx8 | gene:RGD | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog) AND INVOLVED IN early endosome to Golgi transport (ortholog) AND intracellular protein transport (ortholog) AND FOUND IN early endosome membrane (ortholog) AND retromer complex (ortholog) AND INTERACTS WITH C60 fullerene AND furan AND (-)-epigallocatechin 3-gallate (ortholog) | Chr12:14724880..14773455 | 10 |
| Mafk | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN nervous system development AND regulation of transcription DNA-dependent (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr12:15312420..15323137 | 10 |
| Gper | gene:RGD | ENCODES a protein that exhibits drug binding AND hormone binding AND steroid binding AND INVOLVED IN intracellular steroid hormone receptor signaling pathway AND positive regulation of ERK1 and ERK2 cascade AND positive regulation of epidermal growth factor receptor signaling pathway AND PARTICIPATES IN estrogen signaling pathway AND G protein mediated signaling pathway via Galphas family AND FOUND IN plasma membrane AND INTERACTS WITH (S)-amphetamine AND 6-propyl-2-thiouracil AND LY294002 | Chr12:15718615..15719893 | 10 |
| Prkar1b | gene:RGD | ENCODES a protein that exhibits cAMP binding AND cAMP-dependent protein kinase regulator activity AND INVOLVED IN regulation of protein kinase activity AND learning or memory (ortholog) AND PARTICIPATES IN protein kinase A (PKA) signaling pathway AND ASSOCIATED WITH Hypertension (ortholog) AND FOUND IN cAMP-dependent protein kinase complex AND cytoplasm AND INTERACTS WITH C60 fullerene AND cefaloridine AND cisplatin | Chr12:16025867..16131129 | 10 |
| Zfp68 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND INVOLVED IN regulation of transcription DNA-dependent (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 6-propyl-2-thiouracil | Chr12:16534544..16549408 | 10 |
| Taf6 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN DNA-dependent transcription initiation (ortholog) AND negative regulation of cell cycle (ortholog) AND negative regulation of cell proliferation (ortholog) AND FOUND IN MLL1 complex (ortholog) AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr12:17620900..17629268 | 10 |
| Pop7 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND ribonuclease P activity (inferred) AND INVOLVED IN tRNA processing (inferred) AND PARTICIPATES IN RNA transport pathway AND ribosome biogenesis pathway AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr12:19570020..19571061 | 10 |
| Gnb2 | gene:RGD | ENCODES a protein that exhibits calcium channel regulator activity AND GTPase binding (ortholog) AND PARTICIPATES IN chemokine mediated signaling pathway AND glutamate signaling pathway AND FOUND IN cell body AND protein complex AND perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND cocaine | Chr12:19597312..19602329 | 10 |
| Irs3 | gene:RGD | ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding (ortholog) AND PARTICIPATES IN insulin signaling pathway AND aldosterone signaling pathway AND neurotrophic factor signaling pathway AND FOUND IN cytosol AND intracellular membrane-bounded organelle AND plasma membrane AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND N-acetyl-L-cysteine | Chr12:19709141..19711279 | 10 |
| Cldn15 | gene:RGD | ENCODES a protein that exhibits structural molecule activity (inferred) AND PARTICIPATES IN hepatitis C virus infection pathway AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND tight junction (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND benzo[a]pyrene (ortholog) | Chr12:20823334..20845306 | 10 |
| Plod3 | gene:RGD | ENCODES a protein that exhibits procollagen glucosyltransferase activity (ortholog) AND procollagen-lysine 5-dioxygenase activity (ortholog) AND INVOLVED IN cellular response to hormone stimulus AND basement membrane assembly (ortholog) AND collagen fibril organization (ortholog) AND PARTICIPATES IN O-linked glycan biosynthetic pathway AND lysine degradation pathway AND ASSOCIATED WITH Hypothyroidism AND FOUND IN rough endoplasmic reticulum membrane (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND cadmium dichloride | Chr12:20856527..20867088 | 10 |
| Ap1s1 | gene:RGD | ENCODES a protein that exhibits protein transporter activity (inferred) AND INVOLVED IN response to virus (ortholog) AND FOUND IN membrane coat (inferred) AND INTERACTS WITH C60 fullerene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr12:20907855..20918301 | 10 |
| Zp3 | gene:RGD | ENCODES a protein that exhibits acrosin binding (ortholog) AND carbohydrate binding (ortholog) AND manganese ion transmembrane transporter activity (ortholog) AND INVOLVED IN binding of sperm to zona pellucida (ortholog) AND blastocyst formation (ortholog) AND egg coat formation (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND acrosomal vesicle (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND ammonium chloride AND dexamethasone | Chr12:21805746..21812711 | 10 |
| Pom121 | gene:RGD | ENCODES a protein that exhibits structural constituent of nuclear pore AND INVOLVED IN nuclear pore organization AND PARTICIPATES IN RNA transport pathway AND FOUND IN nuclear pore AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr12:22431380..22448734 | 10 |
| Fkbp6 | gene:RGD | ENCODES a protein that exhibits FK506 binding (ortholog) AND peptidyl-prolyl cis-trans isomerase activity (ortholog) AND INVOLVED IN pachytene AND spermatogenesis AND peptidyl-proline modification (ortholog) AND ASSOCIATED WITH azoospermia AND ASSOCIATED WITH Infertility Male AND Williams Syndrome (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr12:22474002..22544784 | 10 |
| Baz1b | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND histone acetyl-lysine binding (ortholog) AND histone binding (ortholog) AND INVOLVED IN ATP-dependent chromatin remodeling (ortholog) AND DNA replication-dependent nucleosome disassembly (ortholog) AND chromatin assembly or disassembly (ortholog) AND FOUND IN WINAC complex (ortholog) AND centromeric heterochromatin (ortholog) AND chromatin remodeling complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr12:22586411..22644378 | 10 |
| Eln | gene:RGD | ENCODES a protein that exhibits extracellular matrix constituent conferring elasticity AND extracellular matrix binding (ortholog) AND INVOLVED IN blood vessel remodeling AND extracellular matrix organization (ortholog) AND regulation of actin filament polymerization (ortholog) AND ASSOCIATED WITH Aortic Aneurysm Abdominal (ortholog) AND Aortic Stenosis Supravalvular (ortholog) AND Aortic Valve Stenosis (ortholog) AND FOUND IN extracellular region AND elastic fiber (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND N-nitrosodiethylamine | Chr12:23033657..23077043 | 10 |
| Limk1 | gene:RGD | ENCODES a protein that exhibits heat shock protein binding (ortholog) AND protein heterodimerization activity (ortholog) AND INVOLVED IN negative regulation of ubiquitin-protein ligase activity (ortholog) AND positive regulation of actin filament bundle assembly (ortholog) AND positive regulation of axon extension (ortholog) AND PARTICIPATES IN Fc gamma receptor mediated signaling pathway AND FOUND IN Golgi apparatus AND axonal growth cone AND nucleus AND INTERACTS WITH Aroclor 1254 AND C60 fullerene AND ammonium chloride | Chr12:23091809..23125717 | 10 |
| Gtf2ird1 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN embryo development (ortholog) AND regulation of transcription DNA-dependent (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 3H-1 2-dithiole-3-thione AND C60 fullerene AND ammonium chloride | Chr12:23319373..23426094 | 10 |
| Sbds | gene:RGD | ENCODES a protein that exhibits microtubule binding (ortholog) AND rRNA binding (ortholog) AND ribosome binding (ortholog) AND INVOLVED IN bone marrow development (ortholog) AND bone mineralization (ortholog) AND cell proliferation (ortholog) AND PARTICIPATES IN ribosome biogenesis pathway AND ASSOCIATED WITH Abnormalities Multiple (ortholog) AND Exocrine Pancreatic Insufficiency (ortholog) AND Hematologic Diseases (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleolus (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND bromobenzene | Chr12:27457313..27466472 | 10 |
| Gusb | gene:RGD | ENCODES a protein that exhibits beta-glucuronidase activity AND carbohydrate binding AND INVOLVED IN carbohydrate metabolic process (ortholog) AND PARTICIPATES IN glycosaminoglycan degradation pathway AND pentose and glucuronate interconversion pathway AND porphyrin and chlorophyll metabolic pathway AND ASSOCIATED WITH Mucopolysaccharidoses (ortholog) AND FOUND IN lysosome AND intracellular membrane-bounded organelle (ortholog) AND INTERACTS WITH (R)-lipoic acid AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr12:27744409..27757755 | 10 |
| Ran | gene:RGD | ENCODES a protein that exhibits GDP binding AND GTP binding AND protein domain specific binding AND INVOLVED IN spermatid development AND actin cytoskeleton organization (ortholog) AND cellular protein complex localization (ortholog) AND PARTICIPATES IN microRNA pathway AND nuclear factor kappa B signaling pathwayRNA transport pathway AND FOUND IN nucleus AND protein complex AND chromatin (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr12:28736786..28739921 | 10 |
| Slc15a4 | gene:RGD | ENCODES a protein that exhibits L-histidine transmembrane transporter activity AND INVOLVED IN histidine transport AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND ammonium chloride | Chr12:30111863..30131134 | 10 |
| Aacs | gene:RGD | ENCODES a protein that exhibits acetoacetate-CoA ligase activity AND butyrate-CoA ligase activity AND INVOLVED IN adipose tissue development AND cellular response to cholesterol AND cellular response to glucose stimulus AND PARTICIPATES IN ketone bodies metabolic pathway AND butanoate metabolic pathway AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Obesity AND FOUND IN cytosol AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr12:32206863..32250583 | 10 |
| Ncor2 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II regulatory region DNA binding AND chromatin binding AND glucocorticoid receptor binding AND INVOLVED IN estrous cycle phase AND lactation AND ovulation cycle AND PARTICIPATES IN Notch signaling pathway AND androgen signaling pathway AND cortisol signaling pathway AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Endometrial Neoplasms (ortholog) AND Osteoarthritis (ortholog) AND FOUND IN chromatin AND nucleus AND histone deacetylase complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr12:32617643..32725753 | 10 |
| Zcchc8 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND FOUND IN catalytic step 2 spliceosome (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2-methylcholine (ortholog) | Chr12:34007470..34029866 | 10 |
| Clip1 | gene:RGD | ENCODES a protein that exhibits microtubule binding (ortholog) AND microtubule plus-end binding (ortholog) AND tubulin binding (ortholog) AND INVOLVED IN microtubule bundle formation (ortholog) AND positive regulation of microtubule polymerization (ortholog) AND PARTICIPATES IN mTOR signaling pathway AND FOUND IN centrosome (ortholog) AND cytoplasm (ortholog) AND cytoplasmic microtubule (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr12:34049773..34155531 | 10 |
| Orai1 | gene:RGD | ENCODES a protein that exhibits store-operated calcium channel activity (ortholog) AND INVOLVED IN positive regulation of calcium ion transport (ortholog) AND regulation of calcium ion transport (ortholog) AND store-operated calcium entry (ortholog) AND FOUND IN integral to plasma membrane (ortholog) AND protein complex (ortholog) AND INTERACTS WITH C60 fullerene AND benzo[a]pyrene AND dibutyl phthalate | Chr12:34631248..34646316 | 10 |
| Anapc5 | gene:RGD | ENCODES a protein that exhibits protein phosphatase binding (ortholog) AND INVOLVED IN protein K11-linked ubiquitination (ortholog) AND PARTICIPATES IN cell cycle pathway mitotic AND ubiquitin/proteasome degradation pathway AND FOUND IN anaphase-promoting complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr12:34850485..34884726 | 10 |
| Anapc7 | gene:RGD | ENCODES a protein that exhibits protein phosphatase binding (ortholog) AND INVOLVED IN protein K11-linked ubiquitination (ortholog) AND PARTICIPATES IN cell cycle pathway mitotic AND ubiquitin/proteasome degradation pathway AND FOUND IN anaphase-promoting complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr12:35327644..35354839 | 10 |
| Gpn3 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND nucleotide binding (inferred) AND FOUND IN protein complex (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND benzo[a]pyrene (ortholog) | Chr12:35384028..35392646 | 10 |
| Fam109a | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity (ortholog) AND INVOLVED IN endosome organization (ortholog) AND receptor recycling (ortholog) AND retrograde transport endosome to Golgi (ortholog) AND FOUND IN clathrin-coated vesicle (ortholog) AND early endosome (ortholog) AND recycling endosome (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 4-\{[(5 5 8 8-tetramethyl-5 6 7 8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ortholog) AND benzo[a]pyrene (ortholog) | Chr12:35917800..35921702 | 10 |
| Atxn2 | gene:RGD | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog) AND protein C-terminus binding (ortholog) AND INVOLVED IN cerebellar Purkinje cell differentiation (ortholog) AND cytoplasmic mRNA processing body assembly (ortholog) AND homeostasis of number of cells (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND cytoplasm (ortholog) AND cytoplasmic stress granule (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr12:35962308..36009114 | 10 |
| Trafd1 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INVOLVED IN response to cytokine stimulus AND negative regulation of innate immune response (ortholog) AND FOUND IN intracellular (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND capsaicin | Chr12:36301824..36315741 | 10 |
| Tpcn1 | gene:RGD | ENCODES a protein that exhibits NAADP-sensitive calcium-release channel activity (ortholog) AND identical protein binding (ortholog) AND FOUND IN endosome membrane (ortholog) AND lysosomal membrane (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 4 4'-diaminodiphenylmethane (ortholog) | Chr12:37140428..37227711 | 10 |
| Sds | gene:RGD | ENCODES a protein that exhibits protein dimerization activity AND L-serine ammonia-lyase activity (ortholog) AND protein homodimerization activity (ortholog) AND INVOLVED IN response to amino acid stimulus AND response to cobalamin AND response to nutrient levels AND PARTICIPATES IN cysteine and methionine metabolic pathway AND glycine serine and threonine metabolic pathway AND FOUND IN cytoplasm (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 2-nitrofluorene | Chr12:37281091..37288403 | 10 |
| Rbm19 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN positive regulation of embryonic development (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleolus (ortholog) AND nucleoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND all-trans-retinoic acid | Chr12:37619153..37704471 | 10 |
| Tesc | gene:RGD | ENCODES a protein that exhibits calcium ion binding (ortholog) AND magnesium ion binding (ortholog) AND phosphatase inhibitor activity (ortholog) AND INVOLVED IN cellular response to retinoic acid (ortholog) AND negative regulation of catalytic activity (ortholog) AND negative regulation of cell proliferation (ortholog) AND FOUND IN cytoplasm (ortholog) AND lamellipodium (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND dibutyl phthalate AND nicotinic acid | Chr12:39669706..39704041 | 10 |
| Fbxo21 | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr12:39719654..39753892 | 10 |
| Prkab1 | gene:RGD | ENCODES a protein that exhibits AMP-activated protein kinase activity AND protein kinase binding AND INVOLVED IN protein heterooligomerization AND regulation of catalytic activity AND PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway AND vascular endothelial growth factor signaling pathwayhypertrophic cardimyopathy pathway AND FOUND IN AMP-activated protein kinase complex AND protein complex AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND ammonium chloride | Chr12:41840866..41851241 | 10 |
| Cit | gene:RGD | ENCODES a protein that exhibits Rho GTPase binding AND protein serine/threonine kinase activity (ortholog) AND INVOLVED IN G2/M transition of mitotic cell cycle AND Golgi organization AND regulation of actin polymerization or depolymerization AND ASSOCIATED WITH Ataxia (ortholog) AND Seizures (ortholog) AND FOUND IN Golgi cisterna AND neuronal cell body AND plasma membrane AND INTERACTS WITH C60 fullerene AND ammonium chloride AND furan | Chr12:41858134..42019601 | 10 |
| Pxn | gene:RGD | ENCODES a protein that exhibits integrin binding AND protein complex binding AND protein kinase binding AND INVOLVED IN activation of MAPK activity (ortholog) AND branching morphogenesis of a tube (ortholog) AND cellular component movement (ortholog) AND PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis AND insulin-like growth factor signaling pathway AND integrin mediated signaling pathway AND FOUND IN focal adhesion AND cell leading edge (ortholog) AND lamellipodium (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND chlorpyrifos | Chr12:42322193..42370507 | 10 |
| Rnf10 | gene:RGD | ENCODES a protein that exhibits transcription regulatory region DNA binding AND INVOLVED IN negative regulation of Schwann cell proliferation AND positive regulation of myelination AND positive regulation of transcription from RNA polymerase II promoter AND FOUND IN nucleus AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr12:42609879..42643662 | 10 |
| Acads | gene:RGD | ENCODES a protein that exhibits acyl-CoA dehydrogenase activity AND butyryl-CoA dehydrogenase activity AND fatty-acyl-CoA binding AND INVOLVED IN butyrate catabolic process AND fatty acid beta-oxidation using acyl-CoA dehydrogenase AND protein homotetramerization AND PARTICIPATES IN fatty acid beta degradation pathway AND butanoate metabolic pathway AND fatty acid metabolic pathway AND ASSOCIATED WITH Colorectal Neoplasms (ortholog) AND FOUND IN mitochondrial matrix AND mitochondrial membrane AND mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND ammonium chloride | Chr12:42765284..42774528 | 10 |
| Oasl2 | gene:RGD | ENCODES a protein that exhibits 2'-5'-oligoadenylate synthetase activity (ortholog) AND double-stranded RNA binding (ortholog) AND INVOLVED IN metabolic process (ortholog) AND purine nucleotide biosynthetic process (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene | Chr12:42996518..43009338 | 10 |
| Foxn4 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (inferred) AND INVOLVED IN cell differentiation (ortholog) AND neuron fate commitment (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 2-methylcholine (ortholog) | Chr12:43372586..43381544 | 10 |
| Selplg | gene:RGD | ENCODES a protein that exhibits carbohydrate binding (inferred) AND INVOLVED IN cellular response to interleukin-6 (ortholog) AND leukocyte tethering or rolling (ortholog) AND PARTICIPATES IN Staphylococcus aureus infection pathway AND ASSOCIATED WITH Carotid Artery Diseases (ortholog) AND Colitis (ortholog) AND FOUND IN plasma membrane (inferred) AND INTERACTS WITH ammonium chloride AND (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr12:43842268..43843560 | 10 |
| Sart3 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN RNA processing (inferred) AND FOUND IN cytoplasm (ortholog) AND intracellular membrane-bounded organelle (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND phenytoin | Chr12:43893486..43921131 | 10 |
| Chek2 | gene:RGD | ENCODES a protein that exhibits kinase activity AND protein kinase activity AND protein serine/threonine kinase activity AND INVOLVED IN DNA damage checkpoint AND protein phosphorylation AND DNA damage induced protein phosphorylation (ortholog) AND PARTICIPATES IN p53 signaling pathway AND cell cycle pathway mitotic AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Breast Neoplasms Male (ortholog) AND Carcinoma Embryonal (ortholog) AND FOUND IN PML body (ortholog) AND chromosome telomeric region (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND L-ascorbic acid AND N-nitrosodiethylamine | Chr12:45933900..45965427 | 10 |
| Ulk1 | gene:RGD | ENCODES a protein that exhibits Rab GTPase binding (ortholog) AND protein complex binding (ortholog) AND protein kinase activity (ortholog) AND INVOLVED IN neuron projection development AND neuron projection regeneration AND Ras protein signal transduction (ortholog) AND PARTICIPATES IN autophagy pathway AND mTOR signaling pathway AND FOUND IN ULK1-ATG13-FIP200 complex (ortholog) AND autophagic vacuole (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND Delta(9)-tetrahydrocannabinol | Chr12:45996251..46022505 | 10 |
| Pus1 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND ligand-dependent nuclear receptor transcription coactivator activity (ortholog) AND pseudouridine synthase activity (ortholog) AND INVOLVED IN metabolic process (ortholog) AND positive regulation of transcription from RNA polymerase II promoter (ortholog) AND tRNA pseudouridine synthesis (ortholog) AND FOUND IN nucleolus (ortholog) AND nucleus (ortholog) AND transcription factor complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr12:46024978..46033733 | 10 |
| Ep400 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND DNA binding (inferred) AND chromatin binding (inferred) AND INVOLVED IN histone H2A acetylation (ortholog) AND histone H4 acetylation (ortholog) AND FOUND IN NuA4 histone acetyltransferase complex (ortholog) AND nuclear speck (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr12:46036453..46143426 | 10 |
| Tnfrsf11a | gene:RGD | ENCODES a protein that exhibits cytokine binding (ortholog) AND transmembrane signaling receptor activity (ortholog) AND tumor necrosis factor-activated receptor activity (ortholog) AND INVOLVED IN response to radiation AND TNFSF11-mediated signaling pathway (ortholog) AND adaptive immune response (ortholog) AND PARTICIPATES IN cytokine mediated signaling pathway AND rheumatoid arthritis pathway AND ASSOCIATED WITH Myocarditis AND Tibial Fractures AND Bone Diseases Developmental (ortholog) AND FOUND IN external side of plasma membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND diarsenic trioxide | Chr13:11958002..12014371 | 10 |
| Vps4b | gene:RGD | ENCODES a protein that exhibits ATP binding (ortholog) AND ATPase activity (ortholog) AND protein C-terminus binding (ortholog) AND INVOLVED IN ATP catabolic process (ortholog) AND cholesterol transport (ortholog) AND endosomal transport (ortholog) AND PARTICIPATES IN endocytic pathway AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND early endosome (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 4 4'-diaminodiphenylmethane (ortholog) | Chr13:12959843..12984933 | 10 |
| QTL:Bp5 | QTL:RGD | Diastolic: 5.6 Systolic: 3.4 | Chr13:23769074..68769074 | 10 |
| Blood pressure QTL 5 | qtl_ont:RGD_Ontology_RDO0005134 | Diastolic:+5.6+++++++++++Systolic:+3.4+ | Chr13:23769074..68769074 | 10 |
| Clasp1 | gene:RGD | ENCODES a protein that exhibits kinetochore binding (ortholog) AND microtubule binding (ortholog) AND microtubule plus-end binding (ortholog) AND INVOLVED IN cell division (ortholog) AND establishment of spindle orientation (ortholog) AND exit from mitosis (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND cell cortex (ortholog) AND centrosomal corona (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr13:31046104..31269294 | 10 |
| Insig2 | gene:RGD | ENCODES a protein that exhibits transcription factor binding AND INVOLVED IN response to fatty acid AND response to insulin stimulus AND response to lipid AND PARTICIPATES IN sterol regulatory element-binding protein signaling pathway AND ASSOCIATED WITH Fatty Liver (ortholog) AND Hypertriglyceridemia (ortholog) AND FOUND IN endoplasmic reticulum AND SREBP-SCAP-Insig complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene | Chr13:33331951..33345132 | 10 |
| Htr5b | gene:RGD | ENCODES a protein that exhibits drug binding AND serotonin binding AND serotonin receptor activity AND INVOLVED IN serotonin receptor signaling pathway AND PARTICIPATES IN calcium signaling pathway AND FOUND IN membrane AND INTERACTS WITH C60 fullerene AND ammonium chloride AND benzo[a]pyrene | Chr13:33545128..33558050 | 10 |
| Ddx18 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATP-dependent helicase activity (inferred) AND RNA binding (inferred) AND FOUND IN nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2-methylcholine (ortholog) | Chr13:33587928..33601436 | 10 |
| Ccnt2 | gene:RGD | ENCODES a protein that exhibits protein kinase binding (inferred) AND INVOLVED IN regulation of cyclin-dependent protein kinase activity (inferred) AND regulation of transcription DNA-dependent (inferred) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:40498884..40540130 | 10 |
| Zranb3 | gene:RGD | ENCODES a protein that exhibits K63-linked polyubiquitin binding (ortholog) AND annealing helicase activity (ortholog) AND endodeoxyribonuclease activity (ortholog) AND INVOLVED IN DNA repair (ortholog) AND DNA rewinding (ortholog) AND DNA strand renaturation (ortholog) AND FOUND IN nuclear replication fork (ortholog) AND INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND aflatoxin B1 (ortholog) | Chr13:40648221..40803738 | 10 |
| C4bpa | gene:RGD | ENCODES a protein that exhibits complement binding (inferred) AND INVOLVED IN complement activation classical pathway (inferred) AND immune response (inferred) AND innate immune response (inferred) AND PARTICIPATES IN coagulation cascade pathway AND complement system pathway AND ASSOCIATED WITH Radiation Pneumonitis (ortholog) AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:43552947..43588565 | 10 |
| Pfkfb2 | gene:RGD | ENCODES a protein that exhibits kinase binding AND 6-phosphofructo-2-kinase activity (ortholog) AND protein kinase binding (ortholog) AND INVOLVED IN glucose catabolic process AND lactate metabolic process AND positive regulation of glucokinase activity AND PARTICIPATES IN fructose and mannose metabolic pathway AND glycolysis pathway AND FOUND IN cytoplasm AND INTERACTS WITH 2-ethoxyethanol AND 2-methoxyethanol AND ammonium chloride | Chr13:43624838..43652660 | 10 |
| Il10 | gene:RGD | ENCODES a protein that exhibits interleukin-10 receptor binding AND cytokine activity (ortholog) AND INVOLVED IN cellular response to estradiol stimulus AND immune response AND negative regulation of apoptotic process AND PARTICIPATES IN Interleukin-10 signaling pathway AND interleukin-4 signaling pathwayEntamoeba histolyca infection pathway AND ASSOCIATED WITH Arthritis Experimental AND Asthma AND Bronchitis Chronic AND FOUND IN extracellular space AND INTERACTS WITH (+)-pilocarpine AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrobenzenesulfonic acid | Chr13:43953900..43957766 | 10 |
| Rassf5 | gene:RGD | ENCODES a protein that exhibits metal ion binding (inferred) AND INVOLVED IN apoptotic process (inferred) AND intracellular signal transduction (inferred) AND signal transduction (inferred) AND PARTICIPATES IN non-small cell lung cancer pathway AND FOUND IN cytoplasm (inferred) AND microtubule (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr13:44121863..44188493 | 10 |
| Srgap2 | gene:RGD | ENCODES a protein that exhibits Rac GTPase activator activity (ortholog) AND Rac GTPase binding (ortholog) AND protein homodimerization activity (ortholog) AND INVOLVED IN actin filament severing (ortholog) AND dendritic spine development (ortholog) AND extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration (ortholog) AND FOUND IN cytoplasm AND nucleus AND cytosol (ortholog) AND INTERACTS WITH C60 fullerene AND rotenone AND (-)-epigallocatechin 3-gallate (ortholog) | Chr13:44239946..44452446 | 10 |
| Ctse | gene:RGD | ENCODES a protein that exhibits aspartic-type endopeptidase activity AND protein homodimerization activity (ortholog) AND INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class II AND protein autoprocessing AND metabolic process (ortholog) AND FOUND IN endosome AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr13:44582911..44605241 | 10 |
| Rab7b | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN late endosome to Golgi transport (ortholog) AND positive regulation of NF-kappaB transcription factor activity (ortholog) AND positive regulation of interleukin-6 production (ortholog) AND PARTICIPATES IN Entamoeba histolyca infection pathway AND phagocytosis pathway AND FOUND IN Golgi apparatus (ortholog) AND late endosome (ortholog) AND lysosome (ortholog) AND INTERACTS WITH aflatoxin B1 (ortholog) | Chr13:44620063..44636864 | 10 |
| Rbbp5 | gene:RGD | ENCODES a protein that exhibits histone methyltransferase activity (H3-K4 specific) (ortholog) AND methylated histone residue binding (ortholog) AND transcription regulatory region DNA binding (ortholog) AND INVOLVED IN histone H3-K4 methylation (ortholog) AND response to DNA damage stimulus (ortholog) AND response to estrogen stimulus (ortholog) AND FOUND IN MLL1 complex (ortholog) AND Set1C/COMPASS complex (ortholog) AND histone methyltransferase complex (ortholog) AND INTERACTS WITH (S)-nicotine (ortholog) AND 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr13:45364906..45391757 | 10 |
| Mdm4 | gene:RGD | ENCODES a protein that exhibits enzyme binding (ortholog) AND INVOLVED IN G0 to G1 transition (ortholog) AND apoptotic process (ortholog) AND cell proliferation (ortholog) AND PARTICIPATES IN p53 signaling pathway AND FOUND IN nucleus (inferred) AND INTERACTS WITH 17beta-estradiol AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr13:45895832..45931421 | 10 |
| Kiss1 | gene:RGD | ENCODES a protein that exhibits kisspeptin receptor binding AND INVOLVED IN elevation of cytosolic calcium ion concentration AND elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway AND generation of ovulation cycle rhythm AND ASSOCIATED WITH early sexual maturation AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Carcinoma Ductal Breast (ortholog) AND Carcinoma Transitional Cell (ortholog) AND FOUND IN apical plasma membrane AND cytoplasm AND extracellular space AND INTERACTS WITH 2 2' 4 4' 5 5'-hexachlorobiphenyl AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr13:46244786..46247288 | 10 |
| Ren | gene:RGD | ENCODES a protein that exhibits endopeptidase activity AND insulin-like growth factor receptor binding AND receptor binding AND INVOLVED IN angiotensin maturation AND beta-amyloid metabolic process AND cellular response to drug AND PARTICIPATES IN renin-angiotensin cascade pathway AND ASSOCIATED WITH increased systemic arterial blood pressure AND ASSOCIATED WITH Diabetic Nephropathies AND Hypertension AND Hypertrophy Left Ventricular AND FOUND IN cytoplasmic part AND extracellular space AND intracellular (ortholog) AND INTERACTS WITH 11-deoxycorticosterone AND 2 2'-iminobis[1-(6-fluoro-3 4-dihydro-2H-chromen-2-yl)ethanol] AND 2 4-dinitrotoluene | Chr13:46262936..46275213 | 10 |
| Zc3h11a | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND INTERACTS WITH 2 4 6-trinitrobenzenesulfonic acid (ortholog) AND aflatoxin B1 (ortholog) AND cisplatin (ortholog) | Chr13:46546434..46585149 | 10 |
| Adora1 | gene:RGD | ENCODES a protein that exhibits G-protein beta/gamma-subunit complex binding AND G-protein coupled adenosine receptor activity AND G-protein coupled receptor binding AND INVOLVED IN G-protein coupled receptor signaling pathway AND activation of MAPKK activity AND adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway AND ASSOCIATED WITH abnormal brain ventricle morphology AND abnormal brain white matter morphology AND decreased circulating free fatty acid level AND ASSOCIATED WITH Cerebral Infarction AND Diabetes Mellitus Experimental AND Diabetic Nephropathies AND FOUND IN asymmetric synapse AND axolemma AND basolateral plasma membrane AND INTERACTS WITH (+)-pilocarpine AND 17beta-estradiol AND C60 fullerene | Chr13:47160292..47192804 | 10 |
| Rabif | gene:RGD | ENCODES a protein that exhibits zinc ion binding (ortholog) AND INVOLVED IN protein transport (inferred) AND small GTPase mediated signal transduction (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND methamphetamine | Chr13:47437336..47448832 | 10 |
| Rnpep | gene:RGD | ENCODES a protein that exhibits aminopeptidase activity AND cobalt ion binding AND copper ion binding AND INVOLVED IN aging AND negative regulation of blood pressure AND proteolysis AND PARTICIPATES IN angiotensin IV signaling pathway AND renin-angiotensin cascade pathway AND ASSOCIATED WITH Hypertension AND Mammary Neoplasms Experimental AND FOUND IN Golgi apparatus AND external side of plasma membrane AND extracellular region AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:48267923..48286295 | 10 |
| Ipo9 | gene:RGD | ENCODES a protein that exhibits histone binding (ortholog) AND protein transporter activity (ortholog) AND INVOLVED IN protein import into nucleus (ortholog) AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND L-methionine (ortholog) AND calcitriol (ortholog) | Chr13:48382355..48433927 | 10 |
| Csrp1 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND FOUND IN nucleus (inferred) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil | Chr13:48750202..48775815 | 10 |
| Phlda3 | gene:RGD | ENCODES a protein that exhibits phosphatidylinositol-3 4 5-trisphosphate binding (ortholog) AND phosphatidylinositol-3 4-bisphosphate binding (ortholog) AND phosphatidylinositol-3 5-bisphosphate binding (ortholog) AND INVOLVED IN induction of apoptosis (ortholog) AND intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog) AND negative regulation of protein kinase B signaling cascade (ortholog) AND FOUND IN intracellular membrane-bounded organelle (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:48789678..48793999 | 10 |
| Pkp1 | gene:RGD | ENCODES a protein that exhibits lamin binding (ortholog) AND INVOLVED IN intermediate filament bundle assembly (ortholog) AND ASSOCIATED WITH Ectodermal Dysplasia (ortholog) AND FOUND IN desmosome (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND bis(2-ethylhexyl) phthalate AND furan | Chr13:48910028..48958983 | 10 |
| Ddx59 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATP-dependent helicase activity (inferred) AND RNA binding (inferred) AND FOUND IN intracellular (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 2-methylcholine (ortholog) AND all-trans-retinoic acid (ortholog) | Chr13:49463559..49488659 | 10 |
| Zfp281 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog) AND sequence-specific DNA binding transcription factor activity (ortholog) AND transcription regulatory region DNA binding (ortholog) AND INVOLVED IN negative regulation of gene expression (ortholog) AND negative regulation of transcription DNA-dependent (ortholog) AND positive regulation of transcription DNA-dependent (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr13:49700599..49704316 | 10 |
| Atp6v1g3 | gene:RGD | ENCODES a protein that exhibits ATPase binding (ortholog) AND hydrogen-exporting ATPase activity phosphorylative mechanism (ortholog) AND INVOLVED IN ATP catabolic process (ortholog) AND ion transmembrane transport (ortholog) AND proton transport (ortholog) AND PARTICIPATES IN oxidative phosphorylation pathway AND phagocytosis pathway AND rheumatoid arthritis pathway AND FOUND IN cytosol AND plasma membrane AND INTERACTS WITH 6-propyl-2-thiouracil AND methimazole AND benzo[a]pyrene (ortholog) | Chr13:51462070..51476522 | 10 |
| Nek7 | gene:RGD | ENCODES a protein that exhibits protein serine/threonine kinase activity AND INVOLVED IN protein phosphorylation (ortholog) AND FOUND IN microtubule organizing center (inferred) AND nucleus (inferred) AND spindle pole (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND dibutyl phthalate AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr13:51679191..51942636 | 10 |
| Cdc73 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II core binding (ortholog) AND INVOLVED IN cellular response to lipopolysaccharide (ortholog) AND endodermal cell fate commitment (ortholog) AND histone H2B ubiquitination (ortholog) AND ASSOCIATED WITH Hyperparathyroidism (ortholog) AND Parathyroid Neoplasms (ortholog) AND FOUND IN Cdc73/Paf1 complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr13:57441674..57534385 | 10 |
| Glrx2 | gene:RGD | ENCODES a protein that exhibits 2 iron 2 sulfur cluster binding (inferred) AND electron carrier activity (inferred) AND metal ion binding (inferred) AND INVOLVED IN response to hydrogen peroxide (ortholog) AND response to organic substance (ortholog) AND FOUND IN mitochondrion (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND diuron AND elemental selenium | Chr13:57567017..57589873 | 10 |
| Uchl5 | gene:RGD | ENCODES a protein that exhibits endopeptidase inhibitor activity (ortholog) AND proteasome binding (ortholog) AND ubiquitin-specific protease activity (ortholog) AND INVOLVED IN forebrain morphogenesis (ortholog) AND lateral ventricle development (ortholog) AND midbrain development (ortholog) AND FOUND IN Ino80 complex (ortholog) AND cytoplasm (ortholog) AND cytosol (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND benzo[a]pyrene AND paclitaxel | Chr13:57605912..57643050 | 10 |
| Rgl1 | gene:RGD | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred) AND INVOLVED IN small GTPase mediated signal transduction (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 1 1 1-trichloro-2 2-bis(4-hydroxyphenyl)ethane AND 2 6-dinitrotoluene AND 3' 5'-cyclic AMP | Chr13:67468218..67754947 | 10 |
| Ncf2 | gene:RGD | ENCODES a protein that exhibits Rac GTPase binding (ortholog) AND protein C-terminus binding (ortholog) AND superoxide-generating NADPH oxidase activity (ortholog) AND INVOLVED IN aging AND cellular response to hormone stimulus AND positive regulation of blood pressure AND PARTICIPATES IN Leishmania infection pathway AND phagocytosis pathway AND ASSOCIATED WITH Burns AND Diabetes Mellitus Experimental AND Hypertension AND FOUND IN cytoplasm AND membrane AND acrosomal vesicle (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 2'-iminobis[1-(6-fluoro-3 4-dihydro-2H-chromen-2-yl)ethanol] AND 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | Chr13:67806516..67834105 | 10 |
| Lamc2 | gene:RGD | ENCODES a protein that exhibits heparin binding (ortholog) AND PARTICIPATES IN Entamoeba histolyca infection pathway AND Toxoplasma gondii infection pathway AND cell-extracellular matrix signaling pathway AND ASSOCIATED WITH Epidermolysis Bullosa Junctional (ortholog) AND FOUND IN cell cortex AND extracellular space AND laminin-2 complex AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND N-nitrosodiethylamine | Chr13:68151074..68211117 | 10 |
| Cacna1e | gene:RGD | ENCODES a protein that exhibits voltage-gated calcium channel activity (ortholog) AND INVOLVED IN behavioral fear response (ortholog) AND behavioral response to pain (ortholog) AND calcium ion transmembrane transport (ortholog) AND PARTICIPATES IN calcium signaling pathway AND mitogen activated protein kinase signaling pathway AND type 2 diabetes mellitus pathway AND ASSOCIATED WITH Hyperglycemia (ortholog) AND FOUND IN perikaryon AND INTERACTS WITH BAPTA AND C60 fullerene AND ammonium chloride | Chr13:69367254..69683943 | 10 |
| Xpr1 | gene:RGD | ENCODES a protein that exhibits receptor activity (ortholog) AND INVOLVED IN response to virus (ortholog) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND indole-3-methanol | Chr13:70238356..70379254 | 10 |
| Qsox1 | gene:RGD | ENCODES a protein that exhibits flavin-linked sulfhydryl oxidase activity (ortholog) AND INVOLVED IN protein thiol-disulfide exchange (ortholog) AND FOUND IN extracellular space (ortholog) AND integral to Golgi membrane (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND corticosterone | Chr13:70739793..70777526 | 10 |
| Tor1aip1 | gene:RGD | ENCODES a protein that exhibits lamin binding AND INVOLVED IN nuclear membrane organization (inferred) AND protein localization to nucleus (inferred) AND FOUND IN nuclear envelope AND INTERACTS WITH ammonium chloride AND gamma-hexachlorocyclohexane AND pregnenolone 16alpha-carbonitrile | Chr13:71042848..71072766 | 10 |
| Abl2 | gene:RGD | ENCODES a protein that exhibits magnesium ion binding (ortholog) AND manganese ion binding (ortholog) AND protein tyrosine kinase activity (ortholog) AND INVOLVED IN actin filament bundle assembly (ortholog) AND actin filament organization (ortholog) AND cellular response to retinoic acid (ortholog) AND PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway AND myocarditis pathway AND ASSOCIATED WITH Leukemia Myelogenous Chronic BCR-ABL Positive (inferred) AND FOUND IN actin cytoskeleton (ortholog) AND INTERACTS WITH C60 fullerene AND dopamine AND fenoldopam | Chr13:71546918..71915301 | 10 |
| Tor3a | gene:RGD | ENCODES a protein that exhibits 3-dehydroquinate dehydratase activity (inferred) AND ATP binding (inferred) AND INVOLVED IN chaperone mediated protein folding requiring cofactor (inferred) AND FOUND IN endoplasmic reticulum lumen (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND N-acetyl-L-cysteine AND N-nitrosodiethylamine | Chr13:71849603..71874034 | 10 |
| Fam20b | gene:RGD | ENCODES a protein that exhibits phosphotransferase activity alcohol group as acceptor (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr13:71877243..71913271 | 10 |
| Serpinc1 | gene:RGD | ENCODES a protein that exhibits heparin binding AND serine-type endopeptidase inhibitor activity AND protease binding (ortholog) AND INVOLVED IN negative regulation of inflammatory response AND response to nutrient AND PARTICIPATES IN glypican signaling pathway AND coagulation cascade pathway AND complement system pathway AND ASSOCIATED WITH Endotoxemia AND Inflammation AND Jaundice AND FOUND IN extracellular space AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND paracetamol | Chr13:76548456..76562724 | 10 |
| Dars2 | gene:RGD | ENCODES a protein that exhibits aspartate-tRNA(Asn) ligase activity (ortholog) AND protein homodimerization activity (ortholog) AND INVOLVED IN tRNA aminoacylation (ortholog) AND PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway AND FOUND IN mitochondrion (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND dibutyl phthalate | Chr13:76599896..76628866 | 10 |
| Prdx6 | gene:RGD | ENCODES a protein that exhibits glutathione peroxidase activity AND peroxidase activity (ortholog) AND phospholipase A2 activity (ortholog) AND INVOLVED IN hydrogen peroxide catabolic process AND bleb assembly (ortholog) AND oxidation-reduction process (ortholog) AND PARTICIPATES IN phenylalanine metabolic pathway AND ASSOCIATED WITH Arteriosclerosis (ortholog) AND Reperfusion Injury (ortholog) AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH (R)-adrenaline AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr13:76824968..76835517 | 10 |
| Tnfsf4 | gene:RGD | ENCODES a protein that exhibits tumor necrosis factor receptor superfamily binding AND tumor necrosis factor receptor binding (ortholog) AND INVOLVED IN T cell proliferation AND cytokine production AND positive regulation of activated T cell proliferation AND PARTICIPATES IN cytokine mediated signaling pathway AND ASSOCIATED WITH abnormal response to transplant AND ASSOCIATED WITH Myocardial Infarction (ortholog) AND FOUND IN cell surface AND extracellular space (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND isoflurane | Chr13:77026337..77050223 | 10 |
| Fmo3 | gene:RGD | ENCODES a protein that exhibits N N-dimethylaniline monooxygenase activity AND NADP binding AND amino acid binding AND INVOLVED IN drug metabolic process AND PARTICIPATES IN phase I biotransformation pathway via cytochrome P450 AND ASSOCIATED WITH Hypertension (ortholog) AND Metabolism Inborn Errors (ortholog) AND FOUND IN intracellular membrane-bounded organelle AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND N-nitrosodiethylamine | Chr13:78659513..78678524 | 10 |
| Sele | gene:RGD | ENCODES a protein that exhibits oligosaccharide binding (ortholog) AND phospholipase binding (ortholog) AND sialic acid binding (ortholog) AND INVOLVED IN inflammatory response AND leukocyte migration AND response to cytokine stimulus AND PARTICIPATES IN eicosanoids signaling pathway AND Plasmodium infection pathway AND Trypanosoma brucei infection pathway AND ASSOCIATED WITH Brain Injuries AND Reperfusion Injury AND Arthritis (ortholog) AND FOUND IN caveola (ortholog) AND coated pit (ortholog) AND cortical cytoskeleton (ortholog) AND INTERACTS WITH (S)-colchicine AND C60 fullerene AND ammonium chloride | Chr13:79813455..79822845 | 10 |
| F5 | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase activity AND INVOLVED IN blood coagulation AND blood circulation (ortholog) AND PARTICIPATES IN coagulation cascade pathway AND protein C anticoagulant pathwaycomplement system pathway AND ASSOCIATED WITH Dysarthria (ortholog) AND Dyspnea (ortholog) AND Femur Head Necrosis (ortholog) AND FOUND IN extracellular region AND extracellular space (ortholog) AND platelet alpha granule (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr13:79934956..79997285 | 10 |
| Slc19a2 | gene:RGD | ENCODES a protein that exhibits thiamine transmembrane transporter activity (ortholog) AND thiamine uptake transmembrane transporter activity (ortholog) AND INVOLVED IN thiamine transport (ortholog) AND ASSOCIATED WITH Anemia Megaloblastic (ortholog) AND Deafness (ortholog) AND Diabetes Mellitus (ortholog) AND FOUND IN plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:80017780..80031777 | 10 |
| Nme7 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND metal ion binding (inferred) AND nucleoside diphosphate kinase activity (inferred) AND INVOLVED IN brain development (ortholog) AND ciliary receptor clustering involved in smoothened signaling pathway (ortholog) AND determination of left/right symmetry (ortholog) AND PARTICIPATES IN purine metabolic pathway AND pyrimidine metabolic pathway AND FOUND IN centrosome (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr13:80073815..80214238 | 10 |
| Dcaf6 | gene:RGD | ENCODES a protein that exhibits ligand-dependent nuclear receptor transcription coactivator activity (ortholog) AND INVOLVED IN positive regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN Cul4-RING ubiquitin ligase complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND 3H-1 2-dithiole-3-thione AND C60 fullerene | Chr13:81082713..81183953 | 10 |
| Pou2f1 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription AND DNA binding (ortholog) AND sequence-specific DNA binding (ortholog) AND INVOLVED IN lens induction in camera-type eye (ortholog) AND negative regulation of transcription DNA-dependent (ortholog) AND olfactory placode formation (ortholog) AND PARTICIPATES IN forkhead class A signaling pathway AND FOUND IN nucleus AND transcription factor complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND ammonium chloride | Chr13:81607326..81739958 | 10 |
| Sdhc | gene:RGD | ENCODES a protein that exhibits electron carrier activity (inferred) AND succinate dehydrogenase activity (inferred) AND INVOLVED IN tricarboxylic acid cycle (inferred) AND PARTICIPATES IN citric acid cycle pathway AND electron transport chain pathwayAlzheimer disease pathway AND ASSOCIATED WITH Paraganglioma (ortholog) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND amiodarone | Chr13:87014569..87035239 | 10 |
| Nit1 | gene:RGD | ENCODES a protein that exhibits hydrolase activity acting on carbon-nitrogen (but not peptide) bonds (inferred) AND INVOLVED IN nitrogen compound metabolic process (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 6-propyl-2-thiouracil AND L-ethionine | Chr13:87242619..87246055 | 10 |
| Ncstn | gene:RGD | ENCODES a protein that exhibits peptidase activity AND endopeptidase activity (ortholog) AND INVOLVED IN protein processing AND T cell proliferation (ortholog) AND beta-amyloid metabolic process (ortholog) AND PARTICIPATES IN Notch signaling pathway AND syndecan signaling pathwayAlzheimer disease pathway AND ASSOCIATED WITH Alzheimer Disease (ortholog) AND FOUND IN lysosomal membrane AND Golgi apparatus (ortholog) AND endoplasmic reticulum (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND toluene | Chr13:88060484..88076493 | 10 |
| Pigm | gene:RGD | ENCODES a protein that exhibits mannosyltransferase activity AND INVOLVED IN GPI anchor biosynthetic process AND PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway AND FOUND IN endoplasmic reticulum membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr13:88377212..88380909 | 10 |
| Slamf9 | gene:RGD | ENCODES a protein that exhibits receptor activity (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4 6-trinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr13:88480177..88482957 | 10 |
| Crp | gene:RGD | ENCODES a protein that exhibits cholesterol binding AND protein homodimerization activity AND low-density lipoprotein particle binding (ortholog) AND INVOLVED IN aging AND cellular response to calcium ion AND cellular response to glucose stimulus AND PARTICIPATES IN classical complement pathway AND Interleukin-6 signaling pathway AND ASSOCIATED WITH Acute Kidney Injury AND Anemia Iron-Deficiency AND Arthritis Rheumatoid AND FOUND IN extracellular space AND filopodium AND growth cone AND INTERACTS WITH (-)-epigallocatechin 3-gallate AND 1 1-dichloroethene AND 2 3 7 8-tetrachlorodibenzodioxine | Chr13:88702243..88703153 | 10 |
| Apcs | gene:RGD | ENCODES a protein that exhibits carbohydrate binding (inferred) AND metal ion binding (inferred) AND INVOLVED IN protein complex assembly AND ASSOCIATED WITH Amyloidosis (ortholog) AND FOUND IN protein complex AND extracellular matrix (ortholog) AND extracellular space (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 3 3' 4 4' 5-pentachlorobiphenyl | Chr13:89112845..89113641 | 10 |
| Olr1583 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND benzo[a]pyrene AND cefaloridine | Chr13:89424463..89425404 | 10 |
| Ifi204 | gene:RGD | ENCODES a protein that exhibits double-stranded DNA binding (ortholog) AND transcription cofactor activity (ortholog) AND INVOLVED IN cellular response to interferon-beta (ortholog) AND inner ear development (ortholog) AND positive regulation of osteoblast differentiation (ortholog) AND FOUND IN cytoplasm (inferred) AND nucleus (inferred) AND INTERACTS WITH indole-3-methanol AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 2 4 6-trinitrobenzenesulfonic acid (ortholog) | Chr13:89752997..89770167 | 10 |
| Olr1590 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr13:89853119..89854066 | 10 |
| Spta1 | gene:RGD | ENCODES a protein that exhibits protein heterodimerization activity (ortholog) AND INVOLVED IN actin cytoskeleton organization (ortholog) AND hemopoiesis (ortholog) AND lymphocyte homeostasis (ortholog) AND ASSOCIATED WITH Elliptocytosis Hereditary (ortholog) AND FOUND IN cortical cytoskeleton (ortholog) AND cuticular plate (ortholog) AND membrane (ortholog) AND INTERACTS WITH C60 fullerene AND phenylephrine AND 1 4-phenylenediamine (ortholog) | Chr13:89951924..90028592 | 10 |
| Olr1601 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH 4 4'-diaminodiphenylmethane (ortholog) AND pregnenolone 16alpha-carbonitrile (ortholog) | Chr13:90101114..90102067 | 10 |
| Olr1602 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND disodium selenite (ortholog) | Chr13:90145460..90146437 | 10 |
| Kmo | gene:RGD | ENCODES a protein that exhibits kynurenine 3-monooxygenase activity AND NAD(P)H oxidase activity (ortholog) AND flavin adenine dinucleotide binding (ortholog) AND INVOLVED IN NAD metabolic process AND tryptophan catabolic process to kynurenine AND kynurenine metabolic process (ortholog) AND PARTICIPATES IN tryptophan metabolic pathway AND FOUND IN mitochondrial outer membrane AND mitochondrion AND mitochondrial inner membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:91363517..91394174 | 10 |
| Adss | gene:RGD | ENCODES a protein that exhibits adenylosuccinate synthase activity AND INVOLVED IN GTP catabolic process AND IMP metabolic process AND aspartate metabolic process AND PARTICIPATES IN de novo purine biosynthetic pathway AND alanine aspartate and glutamate metabolic pathway AND purine metabolic pathway AND ASSOCIATED WITH Sarcoma AND FOUND IN cytoplasm (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND clofibrate AND clofibric acid | Chr13:93681036..93711373 | 10 |
| Hnrnpu | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND INVOLVED IN CRD-mediated mRNA stabilization (ortholog) AND PARTICIPATES IN spliceosome pathway AND FOUND IN CRD-mediated mRNA stability complex (ortholog) AND catalytic step 2 spliceosome (ortholog) AND ribonucleoprotein complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND ammonium chloride | Chr13:93978865..93987654 | 10 |
| Smyd3 | gene:RGD | ENCODES a protein that exhibits histone-lysine N-methyltransferase activity (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cisplatin | Chr13:94643716..95108789 | 10 |
| Tfb2m | gene:RGD | ENCODES a protein that exhibits transcription cofactor activity (ortholog) AND INVOLVED IN positive regulation of transcription DNA-dependent (ortholog) AND transcription from mitochondrial promoter (ortholog) AND transcription initiation from mitochondrial promoter (ortholog) AND FOUND IN mitochondrial matrix (ortholog) AND mitochondrial nucleoid (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:95228520..95246255 | 10 |
| Ahctf1 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN cytokinesis (ortholog) AND nuclear pore complex assembly (ortholog) AND regulation of transcription DNA-dependent (ortholog) AND FOUND IN chromatin (ortholog) AND condensed chromosome kinetochore (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene | Chr13:95432560..95483323 | 10 |
| Adck3 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND protein serine/threonine kinase activity (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND C60 fullerene | Chr13:95869376..95896742 | 10 |
| Psen2 | gene:RGD | ENCODES a protein that exhibits endopeptidase activity (ortholog) AND INVOLVED IN response to hypoxia AND Notch signaling pathway (ortholog) AND T cell activation involved in immune response (ortholog) AND PARTICIPATES IN Alzheimer disease pathway AND Notch signaling pathway AND altered Notch signaling pathway involving the macromolecules modifying the main players AND ASSOCIATED WITH Alzheimer Disease (ortholog) AND Breast Neoplasms (ortholog) AND Hemorrhage (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND Z disc (ortholog) AND centrosome (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND dibutyl phthalate | Chr13:95934674..95951836 | 10 |
| Mixl1 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (inferred) AND sequence-specific DNA binding transcription factor activity (inferred) AND INVOLVED IN cell migration involved in gastrulation (ortholog) AND digestive tract development (ortholog) AND endoderm development (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND aflatoxin B1 (ortholog) | Chr13:96427597..96431628 | 10 |
| Acbd3 | gene:RGD | ENCODES a protein that exhibits fatty-acyl-CoA binding (inferred) AND INVOLVED IN steroid biosynthetic process (inferred) AND transport (inferred) AND FOUND IN Golgi membrane AND Golgi apparatus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr13:96461327..96490328 | 10 |
| Pycr2 | gene:RGD | ENCODES a protein that exhibits nucleotide binding (inferred) AND pyrroline-5-carboxylate reductase activity (inferred) AND INVOLVED IN L-proline biosynthetic process (inferred) AND PARTICIPATES IN arginine and proline metabolic pathway AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH C60 fullerene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr13:96633455..96637249 | 10 |
| Nvl | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND nucleoside-triphosphatase activity (inferred) AND PARTICIPATES IN ribosome biogenesis pathway AND FOUND IN aggresome (ortholog) AND cytoplasm (ortholog) AND nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr13:96862759..96917215 | 10 |
| Srp9 | gene:RGD | ENCODES a protein that exhibits 7S RNA binding (inferred) AND INVOLVED IN SRP-dependent cotranslational protein targeting to membrane (inferred) AND negative regulation of translational elongation (inferred) AND FOUND IN signal recognition particle endoplasmic reticulum targeting (inferred) AND INTERACTS WITH (S)-nicotine (ortholog) AND 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine (ortholog) AND 17alpha-ethynylestradiol (ortholog) | Chr13:98125510..98133650 | 10 |
| Tp53bp2 | gene:RGD | ENCODES a protein that exhibits NF-kappaB binding (ortholog) AND INVOLVED IN central nervous system development (ortholog) AND embryo development ending in birth or egg hatching (ortholog) AND heart development (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND phenytoin | Chr13:98432144..98468555 | 10 |
| Capn2 | gene:RGD | ENCODES a protein that exhibits calcium ion binding AND calcium-dependent cysteine-type endopeptidase activity AND cytoskeletal protein binding AND INVOLVED IN protein autoprocessing AND proteolysis AND response to hypoxia AND PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases AND Alzheimer disease pathway AND Endoplasmic Reticulum-associated degradation pathway AND FOUND IN chromatin (ortholog) AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione | Chr13:98473367..98524463 | 10 |
| Disp1 | gene:RGD | ENCODES a protein that exhibits peptide transporter activity (ortholog) AND INVOLVED IN determination of left/right symmetry (ortholog) AND diaphragm development (ortholog) AND dorsal/ventral pattern formation (ortholog) AND PARTICIPATES IN Hedgehog signaling pathway AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr13:99095659..99242282 | 10 |
| Hlx | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog) AND INVOLVED IN embryonic digestive tract morphogenesis (ortholog) AND enteric nervous system development (ortholog) AND liver development (ortholog) AND PARTICIPATES IN interleukin-12 signaling pathway AND FOUND IN nucleus (inferred) AND INTERACTS WITH cefaloridine AND 4-\{[(5 5 8 8-tetramethyl-5 6 7 8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ortholog) AND 4-hydroxynon-2-enal (ortholog) | Chr13:100685757..100691658 | 10 |
| Bpnt1 | gene:RGD | ENCODES a protein that exhibits 3'(2') 5'-bisphosphate nucleotidase activity AND inositol-1 4-bisphosphate 1-phosphatase activity AND magnesium ion binding AND INVOLVED IN dephosphorylation (ortholog) AND PARTICIPATES IN sulfur metabolic pathway AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:101340544..101367549 | 10 |
| Slc30a10 | gene:RGD | ENCODES a protein that exhibits cation transmembrane transporter activity (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 17beta-estradiol (ortholog) AND 2 4 6-trinitrobenzenesulfonic acid (ortholog) | Chr13:101474867..101492180 | 10 |
| Lyplal1 | gene:RGD | ENCODES a protein that exhibits hydrolase activity (inferred) AND INVOLVED IN negative regulation of Golgi to plasma membrane protein transport (ortholog) AND protein depalmitoylation (ortholog) AND FOUND IN cytosol (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND N-acetyl-L-cysteine AND N-nitrosodiethylamine | Chr13:102143174..102171752 | 10 |
| Smyd2 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II core binding (ortholog) AND histone methyltransferase activity (H3-K36 specific) (ortholog) AND p53 binding (ortholog) AND INVOLVED IN negative regulation of cell proliferation (ortholog) AND negative regulation of transcription from RNA polymerase II promoter (ortholog) AND peptidyl-lysine dimethylation (ortholog) AND PARTICIPATES IN p53 signaling pathway AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND benzo[a]pyrene AND all-trans-retinoic acid (ortholog) | Chr13:106160147..106201473 | 10 |
| Rps6kc1 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND phosphatidylinositol binding (inferred) AND protein kinase activity (inferred) AND INVOLVED IN cell communication (inferred) AND FOUND IN early endosome (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr13:106842538..106989914 | 10 |
| Batf3 | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND protein dimerization activity (inferred) AND protein heterodimerization activity (inferred) AND INVOLVED IN transcription DNA-dependent (inferred) AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 4 6-trinitrotoluene AND ammonium chloride AND diethylstilbestrol | Chr13:107128770..107140194 | 10 |
| Ppp2r5a | gene:RGD | ENCODES a protein that exhibits kinase binding (ortholog) AND INVOLVED IN negative regulation of establishment of protein localization to plasma membrane (ortholog) AND negative regulation of lipid kinase activity (ortholog) AND positive regulation of protein dephosphorylation (ortholog) AND PARTICIPATES IN canonical Wnt signaling pathway AND Wnt signaling pathway AND mRNA decay pathway AND FOUND IN M band (ortholog) AND Z disc (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND perfluorooctane-1-sulfonic acid AND perfluorooctanoic acid | Chr13:107413761..107458156 | 10 |
| Lamb3 | gene:RGD | ENCODES a protein that exhibits protein complex binding AND INVOLVED IN brown fat cell differentiation (ortholog) AND PARTICIPATES IN Entamoeba histolyca infection pathway AND Toxoplasma gondii infection pathway AND cell-extracellular matrix signaling pathway AND ASSOCIATED WITH Epidermolysis Bullosa Junctional (ortholog) AND FOUND IN basement membrane (ortholog) AND laminin-5 complex (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND cefaloridine | Chr13:109148815..109190322 | 10 |
| Plxna2 | gene:RGD | ENCODES a protein that exhibits semaphorin receptor activity (ortholog) AND INVOLVED IN cell surface receptor signaling pathway (ortholog) AND centrosome localization (ortholog) AND cerebellar granule cell precursor tangential migration (ortholog) AND FOUND IN integral to plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND C60 fullerene | Chr13:110555958..110754672 | 10 |
| Vom2r73 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr14:1300254..1310565 | 10 |
| Fgfrl1 | gene:RGD | ENCODES a protein that exhibits fibroblast growth factor binding (ortholog) AND fibroblast growth factor-activated receptor activity (ortholog) AND heparin binding (ortholog) AND INVOLVED IN diaphragm development (ortholog) AND fibroblast growth factor receptor signaling pathway (ortholog) AND heart valve morphogenesis (ortholog) AND FOUND IN plasma membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr14:1550894..1562953 | 10 |
| Glmn | gene:RGD | ENCODES a protein that exhibits hepatocyte growth factor receptor binding (ortholog) AND INVOLVED IN muscle cell differentiation (ortholog) AND negative regulation of T cell proliferation (ortholog) AND positive regulation of cytokine secretion (ortholog) AND ASSOCIATED WITH Arteriovenous Malformations (ortholog) AND Glomus Tumor (ortholog) AND INTERACTS WITH C60 fullerene AND indole-3-methanol AND (-)-epigallocatechin 3-gallate (ortholog) | Chr14:2744359..2789190 | 10 |
| Nudt9 | gene:RGD | ENCODES a protein that exhibits adenosine-diphosphatase activity (ortholog) AND INVOLVED IN ADP catabolic process (ortholog) AND IDP catabolic process (ortholog) AND PARTICIPATES IN purine metabolic pathway AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND cadmium dichloride | Chr14:6809091..6840664 | 10 |
| Hsd17b13 | gene:RGD | ENCODES a protein that exhibits nucleotide binding (inferred) AND oxidoreductase activity (inferred) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr14:6901197..6915871 | 10 |
| Wdfy3 | gene:RGD | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog) AND beta-N-acetylglucosaminylglycopeptide beta-1 4-galactosyltransferase activity (ortholog) AND INVOLVED IN metabolic process (ortholog) AND FOUND IN autophagic vacuole (ortholog) AND cytoplasm (ortholog) AND cytoplasmic part (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND (-)-epigallocatechin 3-gallate (ortholog) | Chr14:8916412..9060345 | 10 |
| Sec31a | gene:RGD | ENCODES a protein that exhibits calcium-dependent protein binding (ortholog) AND INVOLVED IN response to calcium ion (ortholog) AND PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway AND FOUND IN endosome AND ER to Golgi transport vesicle (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione | Chr14:10466582..10522655 | 10 |
| Hnrpdl | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND RNA binding (inferred) AND nucleic acid binding (inferred) AND INVOLVED IN regulation of transcription DNA-dependent (inferred) AND transcription DNA-dependent (inferred) AND FOUND IN cytoplasm (inferred) AND nucleus (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND 17beta-estradiol (ortholog) | Chr14:10861054..10864322 | 10 |
| Naa11 | gene:RGD | ENCODES a protein that exhibits peptide alpha-N-acetyltransferase activity (inferred) AND FOUND IN Golgi apparatus (ortholog) AND centrosome (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr14:13633055..13643091 | 10 |
| Shroom3 | gene:RGD | ENCODES a protein that exhibits actin binding (ortholog) AND INVOLVED IN actin cytoskeleton organization (ortholog) AND columnar/cuboidal epithelial cell development (ortholog) AND neural tube closure (ortholog) AND FOUND IN adherens junction (ortholog) AND apical junction complex (ortholog) AND apical part of cell (ortholog) AND INTERACTS WITH C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND aflatoxin B1 (ortholog) | Chr14:16658357..16954651 | 10 |
| Scarb2 | gene:RGD | ENCODES a protein that exhibits enzyme binding (ortholog) AND INVOLVED IN protein targeting to lysosome (ortholog) AND FOUND IN lysosomal lumen (ortholog) AND lysosomal membrane (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:17119366..17170850 | 10 |
| Cxcl11 | gene:RGD | ENCODES a protein that exhibits chemokine activity AND INVOLVED IN immune response AND PARTICIPATES IN Toll-like receptor signaling pathway AND chemokine mediated signaling pathway AND cytokine mediated signaling pathway AND ASSOCIATED WITH Alveolitis Extrinsic Allergic (ortholog) AND Anthrax (ortholog) AND Bronchiolitis Obliterans (ortholog) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND 2-amino-2-deoxy-D-glucopyranose | Chr14:17250648..17253423 | 10 |
| Cxcl10 | gene:RGD | ENCODES a protein that exhibits chemokine activity AND INVOLVED IN cellular response to heat AND immune response AND negative regulation of angiogenesis AND PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway AND Toll-like receptor signaling pathway AND chemokine mediated signaling pathway AND ASSOCIATED WITH Brain Ischemia AND Bronchiolitis Viral AND Diabetes Mellitus Type 1 AND FOUND IN extracellular space AND external side of plasma membrane (ortholog) AND extracellular region (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene | Chr14:17265986..17268183 | 10 |
| Cxcl9 | gene:RGD | ENCODES a protein that exhibits CXCR3 chemokine receptor binding (inferred) AND chemokine activity (inferred) AND INVOLVED IN defense response to virus (ortholog) AND PARTICIPATES IN interleukin-23 signaling pathway AND Toll-like receptor signaling pathway AND chemokine mediated signaling pathway AND ASSOCIATED WITH Myasthenia Gravis Autoimmune Experimental AND Alveolitis Extrinsic Allergic (ortholog) AND Anthrax (ortholog) AND FOUND IN external side of plasma membrane (ortholog) AND extracellular space (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr14:17284085..17288996 | 10 |
| Afm | gene:RGD | ENCODES a protein that exhibits vitamin E binding (ortholog) AND INVOLVED IN vitamin transport (ortholog) AND FOUND IN extracellular space AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:19049664..19082977 | 10 |
| Gc | gene:RGD | ENCODES a protein that exhibits vitamin D binding AND actin binding (ortholog) AND INVOLVED IN female pregnancy AND lactation AND response to estradiol stimulus AND ASSOCIATED WITH Brain Ischemia AND Carcinoma Hepatocellular AND Carotid Artery Injuries AND FOUND IN axon AND cytosol AND extracellular space AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND ammonium chloride | Chr14:20166243..20197060 | 10 |
| Ambn | gene:RGD | ENCODES a protein that exhibits growth factor activity (ortholog) AND INVOLVED IN cell adhesion (ortholog) AND cell proliferation (ortholog) AND FOUND IN proteinaceous extracellular matrix (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND cadmium dichloride | Chr14:21183338..21196650 | 10 |
| Prol1 | gene:RGD | ENCODES a protein that exhibits endopeptidase inhibitor activity (ortholog) AND peptidase inhibitor activity (ortholog) AND INVOLVED IN negative regulation of endopeptidase activity (ortholog) AND regulation of sensory perception of pain (ortholog) AND FOUND IN extracellular region (ortholog) AND membrane (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND indole-3-methanol | Chr14:21294053..21308816 | 10 |
| Sult1b1 | gene:RGD | ENCODES a protein that exhibits aryl sulfotransferase activity AND sulfotransferase activity (ortholog) AND INVOLVED IN flavonoid metabolic process (ortholog) AND metabolic process (ortholog) AND phenol-containing compound metabolic process (ortholog) AND FOUND IN cytosol (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 3 3' 4 4' 5-pentachlorobiphenyl | Chr14:22019193..22031914 | 10 |
| Polr2b | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND protein kinase activity (ortholog) AND INVOLVED IN protein phosphorylation (ortholog) AND transcription from RNA polymerase II promoter (ortholog) AND PARTICIPATES IN Huntington disease pathway AND purine metabolic pathway AND pyrimidine metabolic pathway AND FOUND IN DNA-directed RNA polymerase II core complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 17beta-estradiol (ortholog) | Chr14:33069966..33107615 | 10 |
| Rest | gene:RGD | ENCODES a protein that exhibits DNA binding AND RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription AND protein complex binding AND INVOLVED IN negative regulation of aldosterone biosynthetic process AND negative regulation of calcium ion-dependent exocytosis AND negative regulation of cortisol biosynthetic process AND PARTICIPATES IN Huntington disease pathway AND FOUND IN chromatin AND nucleus AND protein complex AND INTERACTS WITH 9-cis-retinoic acid AND C60 fullerene AND ammonium chloride | Chr14:33136046..33151142 | 10 |
| Hopx | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding (inferred) AND sequence-specific DNA binding transcription factor activity (inferred) AND INVOLVED IN heart development (ortholog) AND histone deacetylation (ortholog) AND lung alveolus development (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND ammonium chloride | Chr14:33369052..33377948 | 10 |
| Arl9 | gene:RGD | ENCODES a protein that exhibits GTP binding (inferred) AND INVOLVED IN small GTPase mediated signal transduction (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 6-propyl-2-thiouracil AND methimazole AND levonorgestrel (ortholog) | Chr14:33452273..33459278 | 10 |
| Paics | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND INVOLVED IN G1/S transition of mitotic cell cycle AND PARTICIPATES IN de novo purine biosynthetic pathway AND purine metabolic pathway AND ASSOCIATED WITH Schizophrenia (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 6-propyl-2-thiouracil | Chr14:33492707..33509389 | 10 |
| Gnpda2 | gene:RGD | ENCODES a protein that exhibits glucosamine-6-phosphate deaminase activity (inferred) AND INVOLVED IN N-acetylglucosamine metabolic process (inferred) AND carbohydrate metabolic process (inferred) AND PARTICIPATES IN amino sugar metabolic pathway AND nucleotide sugar metabolic pathway AND INTERACTS WITH 2 4-dinitrotoluene AND phenytoin AND 17alpha-ethynylestradiol (ortholog) | Chr14:41048839..41067584 | 10 |
| Ube2k | gene:RGD | ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog) AND ubiquitin-protein ligase activity (ortholog) AND ubiquitin-ubiquitin ligase activity (ortholog) AND INVOLVED IN protein K48-linked ubiquitination (ortholog) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND sodium dichromate | Chr14:45349287..45411823 | 10 |
| Tbc1d19 | gene:RGD | ENCODES a protein that exhibits Rab GTPase activator activity (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) AND 17beta-estradiol (ortholog) | Chr14:61840251..61958275 | 10 |
| Anapc4 | gene:RGD | ENCODES a protein that exhibits protein phosphatase binding (ortholog) AND INVOLVED IN protein K11-linked ubiquitination (ortholog) AND PARTICIPATES IN cell cycle pathway mitotic AND ubiquitin/proteasome degradation pathway AND FOUND IN anaphase-promoting complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND Delta(9)-tetrahydrocannabinol | Chr14:62879772..62911465 | 10 |
| Zcchc4 | gene:RGD | ENCODES a protein that exhibits methyltransferase activity (inferred) AND nucleic acid binding (inferred) AND zinc ion binding (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND benzo[a]pyrene (ortholog) | Chr14:62919537..62960883 | 10 |
| Pi4k2b | gene:RGD | ENCODES a protein that exhibits 1-phosphatidylinositol 4-kinase activity (inferred) AND ATP binding (inferred) AND phosphotransferase activity alcohol group as acceptor (inferred) AND PARTICIPATES IN inositol phosphate metabolic pathway AND phosphatidylinositol 3-kinase signaling pathway AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr14:62975861..63002714 | 10 |
| Lap3 | gene:RGD | ENCODES a protein that exhibits peptidase activity (ortholog) AND INVOLVED IN metabolic process (ortholog) AND PARTICIPATES IN arginine and proline metabolic pathway AND glutathione metabolic pathway AND FOUND IN trans-Golgi network AND cytoplasm (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND bromobenzene | Chr14:70680077..70699061 | 10 |
| Bst1 | gene:RGD | ENCODES a protein that exhibits NAD+ nucleosidase activity (inferred) AND nucleotide binding (inferred) AND PARTICIPATES IN calcium signaling pathway AND monoterpenoid biosynthetic pathway AND niacin metabolic pathway AND ASSOCIATED WITH Arthritis Rheumatoid (ortholog) AND FOUND IN anchored to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND ammonium chloride | Chr14:72404263..72414500 | 10 |
| RGD1565560 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN ribosome (inferred) AND INTERACTS WITH C60 fullerene | Chr14:73523489..73523965 | 10 |
| Rpl9 | gene:RGD | ENCODES a protein that exhibits rRNA binding (inferred) AND structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN cytoplasm (ortholog) AND cytosolic large ribosomal subunit (ortholog) AND nucleolus (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr14:76274247..76274951 | 10 |
| Rrm1-ps1 | gene:RGD | ENCODES a protein that exhibits purine nucleotide binding (ortholog) AND ribonucleoside-diphosphate reductase activity thioredoxin disulfide as acceptor (ortholog) AND INVOLVED IN deoxyribonucleotide biosynthetic process (ortholog) AND protein heterotetramerization (ortholog) AND protein oligomerization (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND corticosterone AND sodium dichromate | Chr14:77408781..77411150 | 10 |
| Zfp509 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH C60 fullerene AND amiodarone (ortholog) AND cyclosporin A (ortholog) | Chr14:77873462..77895156 | 10 |
| Nsg1 | gene:RGD | ENCODES a protein that exhibits dopamine receptor binding (inferred) AND INVOLVED IN dopamine receptor signaling pathway (inferred) AND FOUND IN Golgi membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND ammonium chloride | Chr14:77931947..77953690 | 10 |
| Mrfap1 | gene:RGD | ENCODES a protein that exhibits alpha-mannosidase activity (inferred) AND carbohydrate binding (inferred) AND zinc ion binding (inferred) AND INVOLVED IN mannose metabolic process (inferred) AND FOUND IN nucleus (inferred) AND perinuclear region of cytoplasm (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND cadmium dichloride | Chr14:79587301..79589078 | 10 |
| Ablim2 | gene:RGD | ENCODES a protein that exhibits actin binding (inferred) AND zinc ion binding (inferred) AND INVOLVED IN cytoskeleton organization (inferred) AND positive regulation of transcription from RNA polymerase II promoter (inferred) AND FOUND IN actin cytoskeleton (ortholog) AND cytoplasm (ortholog) AND intermediate filament cytoskeleton (ortholog) AND INTERACTS WITH C60 fullerene AND benzo[a]pyrene AND 4 4'-diaminodiphenylmethane (ortholog) | Chr14:80499878..80624108 | 10 |
| Htra3 | gene:RGD | ENCODES a protein that exhibits serine-type peptidase activity (ortholog) AND INVOLVED IN negative regulation of BMP signaling pathway (ortholog) AND negative regulation of transforming growth factor beta receptor signaling pathway (ortholog) AND proteolysis (ortholog) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH C60 fullerene AND dibutyl phthalate AND diuron | Chr14:80702016..80730742 | 10 |
| Cpz | gene:RGD | ENCODES a protein that exhibits metallocarboxypeptidase activity (inferred) AND zinc ion binding (inferred) AND INVOLVED IN Wnt receptor signaling pathway (inferred) AND proteolysis (inferred) AND FOUND IN proteinaceous extracellular matrix (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND alachlor | Chr14:80857371..80880592 | 10 |
| Adra2c | gene:RGD | ENCODES a protein that exhibits alpha2-adrenergic receptor activity AND G-protein coupled receptor activity (ortholog) AND alpha-2A adrenergic receptor binding (ortholog) AND INVOLVED IN female pregnancy AND negative regulation of uterine smooth muscle contraction AND positive regulation of vasoconstriction AND ASSOCIATED WITH Hyperalgesia AND Neuralgia AND Heart Failure (ortholog) AND FOUND IN axon AND axon terminus AND cytoplasm (ortholog) AND INTERACTS WITH 3H-1 2-dithiole-3-thione AND C60 fullerene AND ammonium chloride | Chr14:81107907..81109610 | 10 |
| Sh3bp2 | gene:RGD | ENCODES a protein that exhibits SH3 domain binding (ortholog) AND ASSOCIATED WITH Cherubism (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND cefaloridine | Chr14:81818728..81855875 | 10 |
| Whsc2 | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND INVOLVED IN negative regulation of transcription elongation from RNA polymerase II promoter (ortholog) AND FOUND IN NELF complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr14:82502840..82526916 | 10 |
| Ctbp1 | gene:RGD | ENCODES a protein that exhibits NAD binding AND protein homodimerization activity AND RNA polymerase II transcription corepressor activity (ortholog) AND INVOLVED IN Golgi organization AND negative regulation of histone H4 acetylation (ortholog) AND negative regulation of histone acetylation (ortholog) AND PARTICIPATES IN Notch signaling pathway AND Wnt signaling pathway AND chronic myeloid leukemia pathway AND FOUND IN cytosol AND nucleus (ortholog) AND transcription factor complex (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND ammonium chloride | Chr14:83022824..83050335 | 10 |
| Ywhah | gene:RGD | ENCODES a protein that exhibits actin binding (ortholog) AND enzyme binding (ortholog) AND glucocorticoid receptor binding (ortholog) AND INVOLVED IN glucocorticoid catabolic process (ortholog) AND glucocorticoid receptor signaling pathway (ortholog) AND intracellular protein transport (ortholog) AND PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway AND mTOR signaling pathway AND phosphatidylinositol 3-kinase-Akt signaling pathway AND ASSOCIATED WITH Schizophrenia (inferred) AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:83448395..83457778 | 10 |
| Zfp278 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND chromatin binding (ortholog) AND INVOLVED IN T cell differentiation (ortholog) AND male gonad development (ortholog) AND positive regulation of transcription DNA-dependent (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND dibutyl phthalate AND asbestos (ortholog) | Chr14:83905714..83936768 | 10 |
| Pik3ip1 | gene:RGD | ENCODES a protein that exhibits phosphatidylinositol 3-kinase catalytic subunit binding (ortholog) AND INVOLVED IN negative regulation of phosphatidylinositol 3-kinase activity (ortholog) AND negative regulation of phosphatidylinositol 3-kinase cascade (ortholog) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND diuron | Chr14:83955895..83967828 | 10 |
| Osbp2 | gene:RGD | ENCODES a protein that exhibits phospholipid binding (inferred) AND INVOLVED IN lipid transport (inferred) AND INTERACTS WITH C60 fullerene AND 17beta-estradiol (ortholog) AND 3 4-methylenedioxymethamphetamine (ortholog) | Chr14:84350465..84511727 | 10 |
| Rnf215 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND 17alpha-ethynylestradiol (ortholog) | Chr14:84761366..84767769 | 10 |
| Sf3a1 | gene:RGD | ENCODES a protein that exhibits RNA binding (ortholog) AND INVOLVED IN mRNA processing (ortholog) AND mRNA splicing via spliceosome (ortholog) AND PARTICIPATES IN spliceosome pathway AND FOUND IN U2-type spliceosomal complex (ortholog) AND catalytic step 2 spliceosome (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr14:84786072..84806825 | 10 |
| Nipsnap1 | gene:RGD | ENCODES a protein that exhibits neurotransmitter binding (ortholog) AND INVOLVED IN sensory perception of pain (ortholog) AND FOUND IN membrane (ortholog) AND mitochondrial inner membrane (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr14:85532437..85556559 | 10 |
| Thoc5 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND INVOLVED IN intronless viral mRNA export from host nucleus (ortholog) AND mRNA export from nucleus (ortholog) AND monocyte differentiation (ortholog) AND PARTICIPATES IN RNA transport pathway AND ASSOCIATED WITH Anemia (ortholog) AND Breast Neoplasms (ortholog) AND Leukopenia (ortholog) AND FOUND IN THO complex (ortholog) AND THO complex part of transcription export complex (ortholog) AND intermediate filament cytoskeleton (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr14:85561381..85612915 | 10 |
| Ewsr1 | gene:RGD | ASSOCIATED WITH Sarcoma Ewing (ortholog) AND FOUND IN Cajal body AND cytoplasm AND nucleolus AND INTERACTS WITH 17beta-estradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:85730483..85758958 | 10 |
| Ewing sarcoma breakpoint region 1 | gene_ont:RGD_Ontology_RDO0005265 | ASSOCIATED WITH Sarcoma Ewing (ortholog) AND FOUND IN Cajal body AND cytoplasm AND nucleolus AND INTERACTS WITH 17beta-estradiol AND 24-dinitrotoluene AND 26-dinitrotoluene | Chr14:85730483..85758958 | 10 |
| Ewing sarcoma breakpoint region 1 | gene_ont:RGD_Ontology_RDO0005309 | ASSOCIATED WITH Sarcoma Ewing (ortholog) AND FOUND IN Cajal body AND cytoplasm AND nucleolus AND INTERACTS WITH 17beta-estradiol AND 24-dinitrotoluene AND 26-dinitrotoluene | Chr14:85730483..85758958 | 10 |
| Pgam2 | gene:RGD | ENCODES a protein that exhibits 2 3-bisphosphoglycerate-dependent phosphoglycerate mutase activity AND cofactor binding AND phosphoglycerate mutase activity AND INVOLVED IN gluconeogenesis AND response to inorganic substance AND response to mercury ion AND PARTICIPATES IN gluconeogenesis pathway AND glycolysis pathwayglycolysis/gluconeogenesis pathway AND ASSOCIATED WITH Deficiency Diseases (ortholog) AND Myoglobinuria (ortholog) AND FOUND IN cytosol AND nucleus AND INTERACTS WITH 3H-1 2-dithiole-3-thione AND C60 fullerene AND ammonium chloride | Chr14:86466055..86468166 | 10 |
| Polm | gene:RGD | ENCODES a protein that exhibits DNA binding (inferred) AND DNA nucleotidylexotransferase activity (inferred) AND DNA-directed DNA polymerase activity (inferred) AND INVOLVED IN B cell differentiation (ortholog) AND somatic hypermutation of immunoglobulin genes (ortholog) AND PARTICIPATES IN non-homologous end joining pathway of double-strand break repair AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr14:86491716..86501294 | 10 |
| Aebp1 | gene:RGD | ENCODES a protein that exhibits carboxypeptidase activity (ortholog) AND transcription corepressor activity (ortholog) AND INVOLVED IN regulation of transcription DNA-dependent (ortholog) AND FOUND IN extracellular matrix (ortholog) AND extracellular space (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 5-aza-2'-deoxycytidine AND C60 fullerene | Chr14:86525748..86535664 | 10 |
| Myl7 | gene:RGD | ENCODES a protein that exhibits calcium ion binding (inferred) AND ASSOCIATED WITH Heart Defects Congenital (ortholog) AND FOUND IN A band (ortholog) AND dendritic spine (ortholog) AND INTERACTS WITH 3H-1 2-dithiole-3-thione AND C60 fullerene AND rosiglitazone | Chr14:86568142..86570122 | 10 |
| Gck | gene:RGD | ENCODES a protein that exhibits ADP binding AND ATP binding AND glucokinase activity AND INVOLVED IN carbohydrate phosphorylation AND cellular glucose homeostasis AND cellular response to glucose starvation AND PARTICIPATES IN glycogen biosynthetic pathway AND glycogen metabolic pathway AND glycolysis pathway AND ASSOCIATED WITH decreased circulating glucose level AND increased circulating free fatty acid level AND increased circulating triglyceride level AND ASSOCIATED WITH Diabetes Mellitus Experimental AND Diabetes Mellitus Type 2 AND Coronary Artery Disease (ortholog) AND FOUND IN actin filament AND cell cortex AND cell cortex part AND INTERACTS WITH 1-naphthyl isothiocyanate AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr14:86572518..86587723 | 10 |
| Ddx56 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATP-dependent helicase activity (inferred) AND RNA binding (inferred) AND INVOLVED IN rRNA processing (inferred) AND FOUND IN nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr14:86985893..86994552 | 10 |
| Zmiz2 | gene:RGD | ENCODES a protein that exhibits ligand-dependent nuclear receptor transcription coactivator activity (ortholog) AND INVOLVED IN positive regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN mitochondrion (ortholog) AND nuclear replication fork (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND clofibric acid | Chr14:87137696..87154183 | 10 |
| RGD1562776 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN ribosome (inferred) AND INTERACTS WITH C60 fullerene | Chr14:89196110..89196479 | 10 |
| Grb10 | gene:RGD | ENCODES a protein that exhibits insulin receptor binding AND SH3/SH2 adaptor activity (ortholog) AND INVOLVED IN insulin receptor signaling pathway AND negative regulation of glycogen biosynthetic process AND positive regulation of phosphorylation AND PARTICIPATES IN insulin signaling pathway AND insulin-like growth factor signaling pathway AND platelet-derived growth factor signaling pathway AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND cisplatin | Chr14:92814797..92911442 | 10 |
| Rab1 | gene:RGD | ENCODES a protein that exhibits GTP binding AND INVOLVED IN ER to Golgi vesicle-mediated transport AND FOUND IN Golgi membrane AND endoplasmic reticulum membrane AND neuronal cell body AND INTERACTS WITH 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione AND ammonium chloride | Chr14:100973039..101027893 | 10 |
| Sertad2 | gene:RGD | ENCODES a protein that exhibits transcription coactivator activity (ortholog) AND INVOLVED IN negative regulation of cell growth (ortholog) AND positive regulation of transcription DNA-dependent (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr14:101372813..101445258 | 10 |
| Cct4 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND unfolded protein binding (inferred) AND INVOLVED IN chaperone mediated protein folding requiring cofactor (inferred) AND protein folding (inferred) AND FOUND IN centrosome (ortholog) AND chaperonin-containing T-complex (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND furan | Chr14:103675110..103687893 | 10 |
| Xpo1 | gene:RGD | ENCODES a protein that exhibits protein domain specific binding AND protein transporter activity (ortholog) AND INVOLVED IN negative regulation of transcription from RNA polymerase II promoter AND protein export from nucleus AND response to drug AND PARTICIPATES IN Hedgehog signaling pathway AND nuclear factor kappa B signaling pathwayRNA transport pathway AND FOUND IN annulate lamellae (ortholog) AND kinetochore (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr14:103943249..103978717 | 10 |
| Papolg | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND polynucleotide adenylyltransferase activity (inferred) AND INVOLVED IN RNA polyadenylation (inferred) AND transcription DNA-dependent (inferred) AND PARTICIPATES IN mRNA decay pathway AND FOUND IN nucleus (inferred) AND INTERACTS WITH C60 fullerene AND Delta(9)-tetrahydrocannabinol AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr14:104800058..104833509 | 10 |
| Mtif2 | gene:RGD | ENCODES a protein that exhibits ribosomal small subunit binding (ortholog) AND translation factor activity nucleic acid binding (ortholog) AND INVOLVED IN regulation of translational initiation (ortholog) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND (S)-nicotine (ortholog) | Chr14:110538911..110559208 | 10 |
| Rps27a | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (ortholog) AND FOUND IN cytosolic small ribosomal subunit AND small ribosomal subunit (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND benzene | Chr14:110559621..110561451 | 10 |
| Rtn4 | gene:RGD | ENCODES a protein that exhibits protein complex binding AND INVOLVED IN aging AND axonal fasciculation AND negative regulation of axon extension AND ASSOCIATED WITH Seizures AND FOUND IN cytoplasm AND endoplasmic reticulum AND integral to endoplasmic reticulum membrane AND INTERACTS WITH 2 6-dinitrotoluene AND Delta(9)-tetrahydrocannabinol AND N-nitrosodiethylamine | Chr14:110725089..110772578 | 10 |
| Sptbn1 | gene:RGD | ENCODES a protein that exhibits protein complex binding AND ankyrin binding (ortholog) AND structural constituent of cytoskeleton (ortholog) AND INVOLVED IN Golgi to plasma membrane protein transport (ortholog) AND SMAD protein import into nucleus (ortholog) AND common-partner SMAD protein phosphorylation (ortholog) AND PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway AND ASSOCIATED WITH Abnormalities Multiple (ortholog) AND Stomach Neoplasms (ortholog) AND FOUND IN protein complex AND M band (ortholog) AND cortical cytoskeleton (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr14:111076741..111246286 | 10 |
| Zfp503 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND benzo[a]pyrene AND diuron | Chr15:2352911..2356699 | 10 |
| Vdac2 | gene:RGD | ENCODES a protein that exhibits nucleotide binding (inferred) AND porin activity (inferred) AND voltage-gated anion channel activity (inferred) AND INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway (ortholog) AND negative regulation of protein polymerization (ortholog) AND PARTICIPATES IN Huntington disease pathway AND Parkinson disease pathway AND calcium signaling pathway AND FOUND IN mitochondrial inner membrane (ortholog) AND mitochondrial nucleoid (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 2 2-tetramine AND 2 6-dinitrotoluene | Chr15:2515297..2528969 | 10 |
| Vcl | gene:RGD | ENCODES a protein that exhibits Rho GTPase binding AND alpha-catenin binding (ortholog) AND dystroglycan binding (ortholog) AND INVOLVED IN adherens junction assembly (ortholog) AND apical junction assembly (ortholog) AND cell adhesion (ortholog) AND PARTICIPATES IN E-cadherin signaling pathway AND vascular endothelial growth factor signaling pathwayEntamoeba histolyca infection pathway AND ASSOCIATED WITH Cardiomyopathy Dilated (ortholog) AND Cardiomyopathy Hypertrophic (ortholog) AND FOUND IN Z disc AND actin filament AND focal adhesion AND INTERACTS WITH 1 3-dinitrobenzene AND 2 6-dinitrotoluene AND 2-methoxyethanol | Chr15:3478214..3576911 | 10 |
| Anxa7 | gene:RGD | ENCODES a protein that exhibits calcium-dependent phospholipid binding AND calcium-dependent protein binding (ortholog) AND INVOLVED IN cellular membrane fusion AND response to calcium ion AND response to organic cyclic compound AND ASSOCIATED WITH Breast Neoplasms (ortholog) AND Colonic Neoplasms (ortholog) AND Lymphoma Non-Hodgkin (ortholog) AND FOUND IN cytosol (ortholog) AND nuclear envelope (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:4047956..4075981 | 10 |
| Dnajc9 | gene:RGD | ENCODES a protein that exhibits heat shock protein binding (inferred) AND unfolded protein binding (inferred) AND INVOLVED IN social behavior (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND cadmium dichloride AND 3-methylcholanthrene (ortholog) | Chr15:4152480..4156756 | 10 |
| Rpl15 | gene:RGD | ENCODES a protein that exhibits structural constituent of ribosome (inferred) AND INVOLVED IN translation (inferred) AND FOUND IN cytosolic large ribosomal subunit (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:9082190..9085473 | 10 |
| Ngly1 | gene:RGD | ENCODES a protein that exhibits metal ion binding (inferred) AND peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity (inferred) AND INVOLVED IN glycoprotein catabolic process (ortholog) AND PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway AND FOUND IN cytoplasm (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND phenytoin AND (-)-epigallocatechin 3-gallate (ortholog) | Chr15:10704196..10750564 | 10 |
| Cadps | gene:RGD | ENCODES a protein that exhibits calcium ion binding AND INVOLVED IN positive regulation of calcium ion-dependent exocytosis AND catecholamine secretion (ortholog) AND synaptic vesicle priming (ortholog) AND FOUND IN cytoplasmic vesicle (ortholog) AND INTERACTS WITH 2 2' 4 4' 5 5'-hexachlorobiphenyl AND 2 6-dinitrotoluene AND 3 3' 4 4' 5-pentachlorobiphenyl | Chr15:13859286..14319814 | 10 |
| Flnb | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND INVOLVED IN skeletal muscle tissue development (ortholog) AND PARTICIPATES IN mitogen activated protein kinase signaling pathway AND ASSOCIATED WITH Bone Diseases Developmental (ortholog) AND Osteochondrodysplasias (ortholog) AND Spinal Diseases (ortholog) AND FOUND IN cytoplasm (ortholog) AND focal adhesion (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 6-dinitrotoluene AND 3 3' 4 4' 5-pentachlorobiphenyl | Chr15:18949027..19082504 | 10 |
| Ero1l | gene:RGD | ENCODES a protein that exhibits oxidoreductase activity (ortholog) AND INVOLVED IN brown fat cell differentiation (ortholog) AND chaperone mediated protein folding requiring cofactor (ortholog) AND endoplasmic reticulum unfolded protein response (ortholog) AND PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway AND FOUND IN endoplasmic reticulum (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND carbon monoxide | Chr15:21169438..21205536 | 10 |
| Gnpnat1 | gene:RGD | ENCODES a protein that exhibits glucosamine 6-phosphate N-acetyltransferase activity AND monosaccharide binding AND INVOLVED IN N-acetylglucosamine metabolic process AND glucosamine metabolic process AND liver development AND PARTICIPATES IN hexosamine biosynthetic pathway AND amino sugar metabolic pathway AND nucleotide sugar metabolic pathway AND FOUND IN Golgi apparatus (ortholog) AND endoplasmic reticulum-Golgi intermediate compartment (ortholog) AND late endosome (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2-amino-2-deoxy-D-glucopyranose (ortholog) AND aflatoxin B1 (ortholog) | Chr15:21272165..21284459 | 10 |
| Cdkn3 | gene:RGD | ENCODES a protein that exhibits protein serine/threonine phosphatase activity (inferred) AND protein tyrosine phosphatase activity (inferred) AND INVOLVED IN cell cycle arrest (inferred) AND FOUND IN perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH (S)-colchicine AND 17alpha-ethynylestradiol AND 2 6-dinitrotoluene | Chr15:22617409..22624922 | 10 |
| Gmfb | gene:RGD | ENCODES a protein that exhibits actin binding (inferred) AND growth factor activity (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cadmium dichloride | Chr15:22664728..22675100 | 10 |
| Cgrrf1 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INVOLVED IN negative regulation of cell growth AND FOUND IN nucleus (inferred) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:22683387..22703833 | 10 |
| Ktn1 | gene:RGD | ENCODES a protein that exhibits kinesin binding (inferred) AND INVOLVED IN microtubule-based movement (inferred) AND FOUND IN endoplasmic reticulum (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND diuron | Chr15:23633479..23722293 | 10 |
| Olr1611 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene | Chr15:26020147..26022189 | 10 |
| Olr1622 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND 4 4'-diaminodiphenylmethane (ortholog) | Chr15:26340325..26341263 | 10 |
| Tep1 | gene:RGD | ENCODES a protein that exhibits RNA binding (ortholog) AND telomerase activity (ortholog) AND INVOLVED IN telomere maintenance via recombination (ortholog) AND FOUND IN ribonucleoprotein complex AND cytoplasm (ortholog) AND nuclear matrix (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND 2 6-dinitrotoluene AND ammonium chloride | Chr15:26802624..26852308 | 10 |
| Chd8 | gene:RGD | ENCODES a protein that exhibits armadillo repeat domain binding AND beta-catenin binding AND ATP binding (ortholog) AND INVOLVED IN canonical Wnt receptor signaling pathway AND negative regulation of Wnt receptor signaling pathway AND negative regulation of transcription DNA-dependent AND PARTICIPATES IN Wnt signaling pathway AND FOUND IN nucleus AND protein complex AND MLL1 complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr15:27642767..27704443 | 10 |
| Olr1641 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride | Chr15:27869372..27870328 | 10 |
| Olr1646 | gene:RGD | ENCODES a protein that exhibits G-protein coupled receptor activity (inferred) AND olfactory receptor activity (inferred) AND INVOLVED IN G-protein coupled receptor signaling pathway (inferred) AND detection of chemical stimulus involved in sensory perception of smell (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND indole-3-methanol | Chr15:32344133..32345077 | 10 |
| Rem2 | gene:RGD | ENCODES a protein that exhibits GTP binding AND GTPase activity AND INVOLVED IN small GTPase mediated signal transduction (inferred) AND FOUND IN membrane AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND ammonium chloride | Chr15:32539996..32544475 | 10 |
| Prmt5 | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND methyltransferase activity (ortholog) AND protein-arginine omega-N symmetric methyltransferase activity (ortholog) AND INVOLVED IN endothelial cell activation (ortholog) AND negative regulation of transcription from RNA polymerase II promoter (ortholog) AND peptidyl-arginine N-methylation (ortholog) AND PARTICIPATES IN homocysteine metabolic pathway AND methionine cycle/metabolic pathway AND p53 signaling pathway AND ASSOCIATED WITH Leydig Cell Tumor (ortholog) AND Seminoma (ortholog) AND FOUND IN protein complex AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr15:32574951..32584336 | 10 |
| Psmb5 | gene:RGD | ENCODES a protein that exhibits peptidase activity (ortholog) AND INVOLVED IN proteasomal ubiquitin-dependent protein catabolic process (ortholog) AND response to oxidative stress (ortholog) AND PARTICIPATES IN ubiquitin/proteasome degradation pathway AND FOUND IN proteasome core complex (ortholog) AND INTERACTS WITH 1 3-dinitrobenzene AND 17alpha-ethynylestradiol AND 2 4 6-trinitrotoluene | Chr15:32689859..32694364 | 10 |
| Bcl2l2 | gene:RGD | ENCODES a protein that exhibits BH domain binding AND protein heterodimerization activity AND INVOLVED IN apoptotic process AND Sertoli cell proliferation (ortholog) AND negative regulation of apoptotic process (ortholog) AND PARTICIPATES IN intrinsic apoptotic pathway AND FOUND IN cytoplasm AND mitochondrion AND cytosol (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND DDE AND ammonium chloride | Chr15:32983165..32988018 | 10 |
| Slc22a17 | gene:RGD | ENCODES a protein that exhibits transmembrane signaling receptor activity (ortholog) AND INVOLVED IN siderophore transport (ortholog) AND FOUND IN integral to organelle membrane (ortholog) AND integral to plasma membrane (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:33008690..33015184 | 10 |
| Dhrs4 | gene:RGD | ENCODES a protein that exhibits 3-keto sterol reductase activity (ortholog) AND alcohol dehydrogenase [NAD(P)+] activity (ortholog) AND carbonyl reductase (NADPH) activity (ortholog) AND INVOLVED IN alcohol metabolic process (ortholog) AND cellular ketone metabolic process (ortholog) AND oxidation-reduction process (ortholog) AND PARTICIPATES IN retinol metabolic pathway AND FOUND IN peroxisome AND mitochondrion (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND amiodarone | Chr15:33609570..33621142 | 10 |
| Pck2 | gene:RGD | ENCODES a protein that exhibits phosphoenolpyruvate carboxykinase (GTP) activity AND phosphoenolpyruvate carboxykinase activity AND INVOLVED IN gluconeogenesis AND oxaloacetate metabolic process AND response to glucocorticoid stimulus AND PARTICIPATES IN gluconeogenesis pathway AND citric acid cycle pathway AND eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma AND FOUND IN mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND Delta(9)-tetrahydrocannabinol | Chr15:33671834..33680613 | 10 |
| Ipo4 | gene:RGD | ENCODES a protein that exhibits protein transporter activity (inferred) AND INVOLVED IN intracellular protein transport (inferred) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND furan | Chr15:33761275..33771195 | 10 |
| Nedd8 | gene:RGD | ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog) AND INVOLVED IN protein neddylation AND response to organic cyclic compound AND protein localization (ortholog) AND PARTICIPATES IN neddylation pathway AND p53 signaling pathway AND proteasome degradation pathway involving cullin-dependent ubiquitin ligases AND ASSOCIATED WITH Astrocytoma (ortholog) AND Liver Diseases Alcoholic (ortholog) AND Parkinson Disease (ortholog) AND FOUND IN nucleus AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr15:33797457..33820624 | 10 |
| Rabggta | gene:RGD | ENCODES a protein that exhibits Rab geranylgeranyltransferase activity AND INVOLVED IN protein geranylgeranylation AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr15:33862275..33868619 | 10 |
| Ripk3 | gene:RGD | ENCODES a protein that exhibits NF-kappaB-inducing kinase activity (ortholog) AND identical protein binding (ortholog) AND protein kinase activity (ortholog) AND INVOLVED IN I-kappaB kinase/NF-kappaB cascade (ortholog) AND activation of protein kinase activity (ortholog) AND induction of apoptosis (ortholog) AND FOUND IN intracellular (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr15:33947406..33956351 | 10 |
| Gzmbl2 | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase activity (inferred) AND INVOLVED IN proteolysis (inferred) AND PARTICIPATES IN interleukin-12 signaling pathway AND INTERACTS WITH 1-chloro-2 4-dinitrobenzene AND 4-(ethoxymethylene)-2-phenyloxazol-5-one AND C60 fullerene | Chr15:35061676..35074048 | 10 |
| Gzmb | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase activity AND peptidase activity (ortholog) AND serine-type peptidase activity (ortholog) AND INVOLVED IN induction of necroptosis by extracellular signals AND positive regulation of cell death AND T cell mediated cytotoxicity (ortholog) AND PARTICIPATES IN allograft rejection pathway AND autoimmune thyroid disease pathway AND graft-versus-host disease pathway AND ASSOCIATED WITH Acute Lung Injury (ortholog) AND Bronchiolitis Obliterans (ortholog) AND Pulmonary Disease Chronic Obstructive (ortholog) AND FOUND IN early endosome AND cytoplasm (ortholog) AND intracellular membrane-bounded organelle (ortholog) AND INTERACTS WITH 1-chloro-2 4-dinitrobenzene AND 4-(ethoxymethylene)-2-phenyloxazol-5-one AND C60 fullerene | Chr15:35195075..35198506 | 10 |
| Pspc1 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND nucleotide binding (inferred) AND INVOLVED IN regulation of transcription DNA-dependent (inferred) AND transcription DNA-dependent (inferred) AND FOUND IN nucleolus (ortholog) AND nucleoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND indole-3-methanol AND 17alpha-ethynylestradiol (ortholog) | Chr15:35718357..35779139 | 10 |
| Gjb2 | gene:RGD | ENCODES a protein that exhibits gap junction channel activity (inferred) AND INVOLVED IN male genitalia development AND ASSOCIATED WITH Deafness (ortholog) AND FOUND IN gap junction AND lateral plasma membrane AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND N-methyl-N'-nitro-N-nitrosoguanidine | Chr15:36153526..36159490 | 10 |
| Cryl1 | gene:RGD | ENCODES a protein that exhibits L-gulonate 3-dehydrogenase activity (ortholog) AND NAD+ binding (ortholog) AND protein homodimerization activity (ortholog) AND INVOLVED IN fatty acid metabolic process (inferred) AND PARTICIPATES IN pentose and glucuronate interconversion pathway AND FOUND IN cytosol (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 2-acetamidofluorene | Chr15:36320075..36440579 | 10 |
| Lats2 | gene:RGD | ENCODES a protein that exhibits ATP binding (ortholog) AND protein serine/threonine kinase activity (ortholog) AND INVOLVED IN G1/S transition of mitotic cell cycle (ortholog) AND cellular protein localization (ortholog) AND hippo signaling cascade (ortholog) AND FOUND IN nucleus (ortholog) AND spindle pole (ortholog) AND INTERACTS WITH 2-methoxyethanol AND C60 fullerene AND (-)-epigallocatechin 3-gallate (ortholog) | Chr15:36720000..36761065 | 10 |
| Kpna3 | gene:RGD | ENCODES a protein that exhibits protein C-terminus binding (ortholog) AND INVOLVED IN protein import into nucleus (inferred) AND FOUND IN cytoplasm (inferred) AND nucleus (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND cyproterone acetate | Chr15:40513214..40585152 | 10 |
| Mtmr9 | gene:RGD | ENCODES a protein that exhibits enzyme regulator activity (ortholog) AND INVOLVED IN regulation of catalytic activity (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr15:42787644..42809678 | 10 |
| Msra | gene:RGD | ENCODES a protein that exhibits peptide-methionine (S)-S-oxide reductase activity AND INVOLVED IN aging AND oxidation-reduction process (ortholog) AND FOUND IN cytoplasm AND mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:43509775..43756283 | 10 |
| Gulo | gene:RGD | ENCODES a protein that exhibits L-gulonolactone oxidase activity (ortholog) AND flavin adenine dinucleotide binding (ortholog) AND INVOLVED IN L-ascorbic acid biosynthetic process (ortholog) AND PARTICIPATES IN ascorbate and aldarate metabolic pathway AND FOUND IN endoplasmic reticulum membrane (inferred) AND integral to membrane (inferred) AND membrane (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 4-dinitrotoluene AND 6-propyl-2-thiouracil | Chr15:45410685..45434014 | 10 |
| Ptk2b | gene:RGD | ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding AND protein complex binding AND non-membrane spanning protein tyrosine kinase activity (ortholog) AND INVOLVED IN MAPK cascade AND actin filament organization AND activation of Janus kinase activity AND PARTICIPATES IN Jak-Stat signaling pathway AND Rho/Rac/Cdc42 mediated signaling pathway AND the extracellular signal-regulated Raf/Mek/Erk signaling pathway AND ASSOCIATED WITH Anti-Glomerular Basement Membrane Disease AND Brain Ischemia AND Hypertrophy Left Ventricular AND FOUND IN axon AND cell cortex AND focal adhesion AND INTERACTS WITH (+)-pilocarpine AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr15:45589222..45717866 | 10 |
| Bnip3l | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND lamin binding (ortholog) AND protein heterodimerization activity (ortholog) AND INVOLVED IN defense response to virus (ortholog) AND induction of apoptosis (ortholog) AND mitochondrial protein catabolic process (ortholog) AND PARTICIPATES IN intrinsic apoptotic pathway AND FOUND IN cytosol AND mitochondrion AND endoplasmic reticulum (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND 2-nitrotoluene AND 3H-1 2-dithiole-3-thione | Chr15:46516626..46539756 | 10 |
| Ppp2r2a | gene:RGD | ENCODES a protein that exhibits protein serine/threonine phosphatase activity (ortholog) AND INVOLVED IN protein dephosphorylation (ortholog) AND response to morphine (ortholog) AND PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway AND Trypanosoma cruzi infection pathway AND hepatitis C virus infection pathway AND FOUND IN protein phosphatase type 2A complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 3H-1 2-dithiole-3-thione | Chr15:46546447..46605977 | 10 |
| Adam7 | gene:RGD | ENCODES a protein that exhibits endopeptidase activity (ortholog) AND INVOLVED IN integrin-mediated signaling pathway (inferred) AND proteolysis (inferred) AND FOUND IN plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND ammonium chloride | Chr15:48184131..48232533 | 10 |
| Nkx3-1 | gene:RGD | ENCODES a protein that exhibits DNA binding (ortholog) AND MADS box domain binding (ortholog) AND RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity (ortholog) AND INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog) AND activation of pro-apoptotic gene products (ortholog) AND androgen receptor signaling pathway (ortholog) AND PARTICIPATES IN forkhead class A signaling pathway AND prostate cancer pathway AND FOUND IN intracellular (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND 17beta-estradiol (ortholog) AND 17beta-hydroxy-17-methylestra-4 9 11-trien-3-one (ortholog) | Chr15:49743313..49745905 | 10 |
| Loxl2 | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND methylated histone residue binding (ortholog) AND protein-lysine 6-oxidase activity (ortholog) AND INVOLVED IN collagen fibril organization (ortholog) AND endothelial cell migration (ortholog) AND endothelial cell proliferation (ortholog) AND FOUND IN basement membrane AND nucleus (ortholog) AND INTERACTS WITH cisplatin AND dopamine AND fenoldopam | Chr15:49982103..50068902 | 10 |
| R3hcc1 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND nucleotide binding (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND benzo[a]pyrene (ortholog) | Chr15:50072604..50088460 | 10 |
| Pdlim2 | gene:RGD | ENCODES a protein that exhibits alpha-actinin binding AND filamin binding AND muscle alpha-actinin binding AND FOUND IN cortical actin cytoskeleton AND stress fiber AND actin cytoskeleton (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene | Chr15:50564108..50575871 | 10 |
| Slc39a14 | gene:RGD | ENCODES a protein that exhibits ferrous iron transmembrane transporter activity (ortholog) AND zinc ion transmembrane transporter activity (ortholog) AND INVOLVED IN cellular zinc ion homeostasis (ortholog) AND ferrous iron transport (ortholog) AND iron ion transmembrane transport (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND endoplasmic reticulum (ortholog) AND integral to membrane (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND phenacetin AND phenylhydrazine | Chr15:50703198..50749644 | 10 |
| Epb49 | gene:RGD | ENCODES a protein that exhibits actin binding (inferred) AND INVOLVED IN cytoskeleton organization (inferred) AND FOUND IN cortical cytoskeleton (ortholog) AND cytoplasm (ortholog) AND membrane (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND phenytoin | Chr15:51004498..51032118 | 10 |
| Med4 | gene:RGD | ENCODES a protein that exhibits RNA polymerase II transcription cofactor activity (ortholog) AND receptor activity (ortholog) AND thyroid hormone receptor binding (ortholog) AND INVOLVED IN androgen receptor signaling pathway (ortholog) AND intracellular steroid hormone receptor signaling pathway (ortholog) AND positive regulation of transcription DNA-dependent (ortholog) AND FOUND IN mediator complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 3H-1 2-dithiole-3-thione AND pregnenolone 16alpha-carbonitrile | Chr15:54158386..54168660 | 10 |
| Sucla2 | gene:RGD | ENCODES a protein that exhibits succinate-CoA ligase (ADP-forming) activity AND INVOLVED IN succinate metabolic process AND succinyl-CoA metabolic process AND tricarboxylic acid cycle AND PARTICIPATES IN citric acid cycle pathway AND propanoate metabolic pathway AND FOUND IN mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:54214262..54267830 | 10 |
| Esd | gene:RGD | ENCODES a protein that exhibits hydrolase activity acting on ester bonds (ortholog) AND INVOLVED IN metabolic process (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND L-ethionine | Chr15:55556681..55576172 | 10 |
| Cpb2 | gene:RGD | ENCODES a protein that exhibits carboxypeptidase activity AND INVOLVED IN fibrinolysis AND negative regulation of fibrinolysis AND proteolysis AND PARTICIPATES IN coagulation cascade pathway AND complement system pathway AND ASSOCIATED WITH Burns AND Sepsis AND Angina Pectoris (ortholog) AND FOUND IN extracellular space AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:56104920..56154321 | 10 |
| Cog3 | gene:RGD | ENCODES a protein that exhibits protein transporter activity (ortholog) AND INVOLVED IN ER to Golgi vesicle-mediated transport (ortholog) AND intra-Golgi vesicle-mediated transport (ortholog) AND protein glycosylation (ortholog) AND FOUND IN Golgi apparatus (ortholog) AND Golgi transport complex (ortholog) AND cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr15:56600798..56648037 | 10 |
| Gtf2f2 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATP-dependent helicase activity (inferred) AND DNA binding (inferred) AND INVOLVED IN positive regulation of transcription from RNA polymerase II promoter AND FOUND IN microtubule cytoskeleton (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr15:56803445..56925046 | 10 |
| Nufip1 | gene:RGD | ENCODES a protein that exhibits RNA binding (ortholog) AND identical protein binding (ortholog) AND protein binding bridging (ortholog) AND INVOLVED IN box C/D snoRNP assembly (ortholog) AND positive regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN cytosolic ribosome (ortholog) AND nuclear matrix (ortholog) AND nucleolus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND sodium dichromate | Chr15:57028109..57058834 | 10 |
| Akap11 | gene:RGD | ENCODES a protein that exhibits kinase regulator activity AND protein complex scaffold AND protein kinase A catalytic subunit binding AND INVOLVED IN regulation of phosphorylation AND regulation of protein kinase A signaling cascade AND PARTICIPATES IN protein kinase A (PKA) signaling pathway AND FOUND IN cytoplasm AND peroxisome AND protein complex AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 2-methoxyethanol | Chr15:59649461..59679551 | 10 |
| Wbp4 | gene:RGD | ENCODES a protein that exhibits proline-rich region binding (ortholog) AND INVOLVED IN mRNA cis splicing via spliceosome (ortholog) AND FOUND IN nuclear speck (ortholog) AND nucleus (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr15:61517401..61543453 | 10 |
| Pcdh17 | gene:RGD | ENCODES a protein that exhibits calcium ion binding (inferred) AND INVOLVED IN homophilic cell adhesion (inferred) AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND INTERACTS WITH C60 fullerene AND astemizole AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr15:66391901..66482530 | 10 |
| Tdrd3 | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND methylated histone residue binding (ortholog) AND transcription coactivator activity (ortholog) AND INVOLVED IN chromatin modification (inferred) AND mRNA processing (inferred) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND (-)-epigallocatechin 3-gallate (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr15:69605244..69739566 | 10 |
| Uchl3 | gene:RGD | ENCODES a protein that exhibits peptidase activity (ortholog) AND ubiquitin binding (ortholog) AND INVOLVED IN adult walking behavior (ortholog) AND cellular response to insulin stimulus (ortholog) AND eating behavior (ortholog) AND FOUND IN cytoplasm (ortholog) AND mitochondrion (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND ammonium chloride | Chr15:85628490..85670420 | 10 |
| Lmo7 | gene:RGD | ENCODES a protein that exhibits actinin binding AND protein C-terminus binding AND INVOLVED IN cell-cell adhesion AND FOUND IN apical plasma membrane AND cell-cell adherens junction AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr15:85710975..85928469 | 10 |
| Fbxl3 | gene:RGD | ENCODES a protein that exhibits ubiquitin-protein ligase activity (ortholog) AND INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (ortholog) AND proteasomal ubiquitin-dependent protein catabolic process (ortholog) AND regulation of circadian rhythm (ortholog) AND FOUND IN SCF ubiquitin ligase complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cocaine | Chr15:87093141..87113003 | 10 |
| Mycbp2 | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity (ortholog) AND INVOLVED IN branchiomotor neuron axon guidance (ortholog) AND cell morphogenesis involved in neuron differentiation (ortholog) AND central nervous system projection neuron axonogenesis (ortholog) AND FOUND IN axon (ortholog) AND microtubule cytoskeleton (ortholog) AND INTERACTS WITH 6-propyl-2-thiouracil AND L-ethionine AND amiodarone | Chr15:87124558..87364839 | 10 |
| Dct | gene:RGD | ENCODES a protein that exhibits dopachrome isomerase activity (ortholog) AND INVOLVED IN cell development (ortholog) AND developmental pigmentation (ortholog) AND melanin biosynthetic process (ortholog) AND PARTICIPATES IN tyrosine metabolic pathway AND FOUND IN cytoplasm (ortholog) AND cytosol (ortholog) AND melanosome (ortholog) AND INTERACTS WITH diuron AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 5 6-dihydroxyindole-2-carboxylic acid (ortholog) | Chr15:102798699..102832240 | 10 |
| Tgds | gene:RGD | ENCODES a protein that exhibits coenzyme binding (inferred) AND dTDP-glucose 4 6-dehydratase activity (inferred) AND nucleotide binding (inferred) AND INVOLVED IN nucleotide-sugar metabolic process (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND cyclosporin A (ortholog) AND etoposide (ortholog) | Chr15:102906505..102927476 | 10 |
| Dnajc3 | gene:RGD | ENCODES a protein that exhibits chaperone binding (ortholog) AND misfolded protein binding (ortholog) AND INVOLVED IN proteolysis involved in cellular protein catabolic process (ortholog) AND PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway AND influenza A virus infection pathway AND FOUND IN cytoplasm (ortholog) AND endoplasmic reticulum Sec complex (ortholog) AND endoplasmic reticulum lumen (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil | Chr15:103881634..103921295 | 10 |
| Ipo5 | gene:RGD | ENCODES a protein that exhibits protein transporter activity (inferred) AND INVOLVED IN ribosomal protein import into nucleus (ortholog) AND FOUND IN intracellular (inferred) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2-methoxyethanol AND C60 fullerene | Chr15:105944155..106021407 | 10 |
| Farp1 | gene:RGD | ENCODES a protein that exhibits Rho guanyl-nucleotide exchange factor activity (inferred) AND phospholipid binding (inferred) AND INVOLVED IN negative regulation of phosphatase activity (ortholog) AND FOUND IN cytoskeleton (inferred) AND INTERACTS WITH 17beta-estradiol AND C60 fullerene AND diuron | Chr15:106171848..106253441 | 10 |
| Timm8a2 | gene:RGD | ENCODES a protein that exhibits metal ion binding (inferred) AND INVOLVED IN protein import into mitochondrial inner membrane (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH C60 fullerene AND furan | Chr15:107145036..107148697 | 10 |
| Tm9sf2 | gene:RGD | ASSOCIATED WITH Precursor Cell Lymphoblastic Leukemia-Lymphoma (ortholog) AND FOUND IN endosome membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr15:107228796..107281296 | 10 |
| transmembrane 9 superfamily member 2 | gene_ont:RGD_Ontology_RDO0004950 | ASSOCIATED WITH Precursor Cell Lymphoblastic Leukemia-Lymphoma (ortholog) AND FOUND IN endosome membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 26-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2378-tetrachlorodibenzodioxine (ortholog) | Chr15:107228796..107281296 | 10 |
| transmembrane 9 superfamily member 2 | gene_ont:RGD_Ontology_RDO0005309 | ASSOCIATED WITH Precursor Cell Lymphoblastic Leukemia-Lymphoma (ortholog) AND FOUND IN endosome membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 26-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2378-tetrachlorodibenzodioxine (ortholog) | Chr15:107228796..107281296 | 10 |
| transmembrane 9 superfamily member 2 | gene_ont:RGD_Ontology_RDO0005741 | ASSOCIATED WITH Precursor Cell Lymphoblastic Leukemia-Lymphoma (ortholog) AND FOUND IN endosome membrane (inferred) AND integral to membrane (inferred) AND INTERACTS WITH 26-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) AND 2378-tetrachlorodibenzodioxine (ortholog) | Chr15:107228796..107281296 | 10 |
| Clybl | gene:RGD | ENCODES a protein that exhibits carbon-carbon lyase activity (inferred) AND citrate (pro-3S)-lyase activity (inferred) AND metal ion binding (inferred) AND INVOLVED IN cellular aromatic compound metabolic process (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr15:107313924..107539458 | 10 |
| Pcca | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND biotin carboxylase activity (inferred) AND metal ion binding (inferred) AND INVOLVED IN cellular amino acid catabolic process (inferred) AND fatty acid catabolic process (inferred) AND PARTICIPATES IN glyoxylate and dicarboxylate metabolic pathway AND propanoate metabolic pathway AND valine leucine and isoleucine degradation pathway AND ASSOCIATED WITH Amino Acid Metabolism Inborn Errors (ortholog) AND FOUND IN mitochondrion AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND dibutyl phthalate | Chr15:107659723..108028929 | 10 |
| DA.WOKW-(D16Rat88-D16Wox7)/K | congenic:RGD_Rat_Strain | A cross of DA/K and WOKW/K which resulted in a segment of chr 16 from WOKW/K introgressed in DA/K background | Chr16:819225..63306215 | 10 |
| Zcchc24 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND cisplatin | Chr16:1310191..1361259 | 10 |
| Anxa11 | gene:RGD | ENCODES a protein that exhibits S100 protein binding (ortholog) AND calcium ion binding (ortholog) AND calcium-dependent phospholipid binding (ortholog) AND INVOLVED IN cytokinesis completion of separation (ortholog) AND phagocytosis (ortholog) AND response to calcium ion (ortholog) AND FOUND IN azurophil granule (ortholog) AND cytoplasm (ortholog) AND midbody (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND cadmium dichloride AND furan | Chr16:1449907..1496053 | 10 |
| Arhgef3 | gene:RGD | ENCODES a protein that exhibits Rho guanyl-nucleotide exchange factor activity (inferred) AND phospholipid binding (inferred) AND INVOLVED IN intracellular signal transduction (inferred) AND regulation of Rho protein signal transduction (inferred) AND FOUND IN intracellular (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr16:2595636..2665051 | 10 |
| Cacna2d3 | gene:RGD | ENCODES a protein that exhibits voltage-gated calcium channel activity AND INVOLVED IN calcium ion transport AND PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway AND dilated cardiomyopathy pathway AND hypertrophic cardimyopathy pathway AND FOUND IN voltage-gated calcium channel complex (inferred) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND tamoxifen | Chr16:4173412..5059574 | 10 |
| Itih4 | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred) AND INVOLVED IN hyaluronan metabolic process (inferred) AND ASSOCIATED WITH Angina Unstable (ortholog) AND Hypercholesterolemia (ortholog) AND Myocardial Infarction (ortholog) AND FOUND IN cytoplasm (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr16:6319608..6334782 | 10 |
| Itih3 | gene:RGD | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred) AND INVOLVED IN hyaluronan metabolic process (inferred) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND ammonium chloride | Chr16:6341043..6358767 | 10 |
| Glt8d1 | gene:RGD | ENCODES a protein that exhibits transferase activity transferring glycosyl groups (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND corticosterone | Chr16:6429357..6444262 | 10 |
| Nisch | gene:RGD | ENCODES a protein that exhibits G-protein coupled amine receptor activity AND INVOLVED IN glucose metabolic process AND norepinephrine secretion AND regulation of blood pressure AND ASSOCIATED WITH Hypertension AND FOUND IN membrane AND INTERACTS WITH 2 6-dinitrotoluene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) AND 2-butoxyethanol (ortholog) | Chr16:6601521..6637734 | 10 |
| Bap1 | gene:RGD | ENCODES a protein that exhibits chromatin binding (ortholog) AND ubiquitin thiolesterase activity (ortholog) AND ubiquitin-specific protease activity (ortholog) AND INVOLVED IN monoubiquitinated histone H2A deubiquitination (ortholog) AND protein K48-linked deubiquitination (ortholog) AND protein deubiquitination (ortholog) AND FOUND IN PR-DUB complex (ortholog) AND cytoplasm (ortholog) AND intracellular membrane-bounded organelle (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND (S)-nicotine (ortholog) AND 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine (ortholog) | Chr16:6684470..6693296 | 10 |
| Oxnad1 | gene:RGD | ENCODES a protein that exhibits oxidoreductase activity (inferred) AND FOUND IN mitochondrion (ortholog) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND perfluorooctanoic acid | Chr16:7546368..7575437 | 10 |
| Timm23 | gene:RGD | ENCODES a protein that exhibits enzyme binding AND INVOLVED IN intracellular protein transport AND FOUND IN mitochondrial inner membrane AND integral to mitochondrial inner membrane (ortholog) AND mitochondrial inner membrane presequence translocase complex (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene AND ammonium chloride | Chr16:7663204..7689233 | 10 |
| Ogdhl | gene:RGD | ENCODES a protein that exhibits oxoglutarate dehydrogenase (succinyl-transferring) activity (inferred) AND thiamine pyrophosphate binding (inferred) AND INVOLVED IN tricarboxylic acid cycle (inferred) AND PARTICIPATES IN citric acid cycle pathway AND lysine degradation pathway AND tryptophan metabolic pathway AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND indole-3-methanol | Chr16:7837198..7859438 | 10 |
| Ercc6 | gene:RGD | ENCODES a protein that exhibits ATP binding (ortholog) AND DNA binding (ortholog) AND DNA-dependent ATPase activity (ortholog) AND INVOLVED IN DNA repair (ortholog) AND activation of JNKK activity (ortholog) AND activation of JUN kinase activity (ortholog) AND PARTICIPATES IN nucleotide excision repair pathway AND FOUND IN nucleolus (ortholog) AND nucleoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND cadmium dichloride | Chr16:8024881..8091587 | 10 |
| Sftpa1 | gene:RGD | ENCODES a protein that exhibits bacterial cell surface binding AND INVOLVED IN cellular response to mechanical stimulus AND cellular response to nitric oxide AND circadian rhythm AND PARTICIPATES IN forkhead class A signaling pathway AND phagocytosis pathway AND ASSOCIATED WITH Asthma AND Hyperoxia AND Lung Diseases AND FOUND IN cytoplasmic vesicle AND extracellular space AND multivesicular body AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 6-propyl-2-thiouracil AND ammonium chloride | Chr16:17570887..17574389 | 10 |
| Mbl1 | gene:RGD | ENCODES a protein that exhibits calcium ion binding AND calcium-dependent protein binding AND mannose binding AND INVOLVED IN complement activation lectin pathway AND defense response to Gram-positive bacterium (ortholog) AND killing by host of symbiont cells (ortholog) AND PARTICIPATES IN Staphylococcus aureus infection pathway AND coagulation cascade pathway AND complement system pathway AND ASSOCIATED WITH Myocardial Reperfusion Injury AND Obesity (ortholog) AND Reperfusion Injury (ortholog) AND FOUND IN extracellular space AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr16:17591820..17597859 | 10 |
| Cherp | gene:RGD | ENCODES a protein that exhibits ion channel binding (ortholog) AND INVOLVED IN cellular calcium ion homeostasis (ortholog) AND negative regulation of cell proliferation (ortholog) AND positive regulation of NFAT protein import into nucleus (ortholog) AND PARTICIPATES IN spliceosome pathway AND FOUND IN sarcoplasmic reticulum membrane AND cytoplasm (ortholog) AND perinuclear region of cytoplasm (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND N-nitrosodiethylamine | Chr16:17785631..17798683 | 10 |
| Calr3 | gene:RGD | ENCODES a protein that exhibits calcium ion binding (inferred) AND unfolded protein binding (inferred) AND INVOLVED IN protein folding (inferred) AND FOUND IN endoplasmic reticulum (inferred) AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2 4-dinitrotoluene AND cadmium dichloride | Chr16:17814237..17842744 | 10 |
| Rab8a | gene:RGD | ENCODES a protein that exhibits protein kinase binding AND INVOLVED IN axonogenesis AND regulation of long-term neuronal synaptic plasticity AND regulation of protein localization AND PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway AND Rab family mediated signaling pathway AND FOUND IN Golgi apparatus AND cytoplasmic membrane-bounded vesicle AND dendrite AND INTERACTS WITH 2 6-dinitrotoluene AND ammonium chloride AND haloperidol | Chr16:18078519..18099882 | 10 |
| Zfp709 | gene:RGD | ENCODES a protein that exhibits nucleic acid binding (inferred) AND zinc ion binding (inferred) AND INVOLVED IN cellular response to heat AND cellular response to lipopolysaccharide AND FOUND IN plasma membrane AND INTERACTS WITH 2 4 6-trinitrotoluene AND ammonium chloride AND (-)-epigallocatechin 3-gallate (ortholog) | Chr16:18397910..18407047 | 10 |
| Nr2f6 | gene:RGD | ENCODES a protein that exhibits sequence-specific DNA binding AND sequence-specific DNA binding transcription factor activity AND INVOLVED IN negative regulation of transcription from RNA polymerase II promoter AND detection of temperature stimulus involved in sensory perception of pain (ortholog) AND entrainment of circadian clock by photoperiod (ortholog) AND FOUND IN nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr16:18535181..18542627 | 10 |
| Abhd8 | gene:RGD | ENCODES a protein that exhibits hydrolase activity (inferred) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND dibutyl phthalate | Chr16:18628138..18634875 | 10 |
| Plvap | gene:RGD | ENCODES a protein that exhibits protein homodimerization activity AND FOUND IN caveola AND integral to membrane AND cytoplasm (ortholog) AND INTERACTS WITH 1 2 4-trimethylbenzene AND C60 fullerene AND ammonium chloride | Chr16:18668569..18678431 | 10 |
| Pgls | gene:RGD | ENCODES a protein that exhibits 6-phosphogluconolactonase activity AND monosaccharide binding AND INVOLVED IN pentose-phosphate shunt oxidative branch AND pentose-phosphate shunt (ortholog) AND PARTICIPATES IN pentose phosphate pathway - oxidative phase AND pentose phosphate pathway AND FOUND IN cytoplasm (inferred) AND INTERACTS WITH cadmium dichloride AND chlorpyrifos AND dibutyl phthalate | Chr16:18791241..18796727 | 10 |
| Slc5a5 | gene:RGD | ENCODES a protein that exhibits sodium:iodide symporter activity AND iodide transmembrane transporter activity (ortholog) AND symporter activity (ortholog) AND INVOLVED IN iodide transport AND sodium ion transport AND anion transport (ortholog) AND ASSOCIATED WITH Congenital Hypothyroidism (ortholog) AND FOUND IN plasma membrane AND nucleus (ortholog) AND INTERACTS WITH 17beta-estradiol AND 6-propyl-2-thiouracil AND adenosine | Chr16:19046200..19056281 | 10 |
| Rab3a | gene:RGD | ENCODES a protein that exhibits ATPase activator activity AND ATPase binding AND GTP binding AND INVOLVED IN positive regulation of ATPase activity AND GTP catabolic process (ortholog) AND axonogenesis (ortholog) AND PARTICIPATES IN insulin secretion pathway AND FOUND IN cytosol AND intracellular organelle AND membrane AND INTERACTS WITH C60 fullerene AND ammonium chloride AND cocaine | Chr16:19189765..19193874 | 10 |
| Pde4c | gene:RGD | ENCODES a protein that exhibits 3' 5'-cyclic-AMP phosphodiesterase activity AND drug binding AND INVOLVED IN cAMP catabolic process AND negative regulation of insulin secretion AND PARTICIPATES IN protein kinase A (PKA) signaling pathway AND purine metabolic pathway AND FOUND IN primary cilium (ortholog) AND INTERACTS WITH C60 fullerene AND ammonium chloride AND 17beta-estradiol (ortholog) | Chr16:19197277..19215627 | 10 |
| Crlf1 | gene:RGD | ENCODES a protein that exhibits ciliary neurotrophic factor receptor binding (ortholog) AND cytokine activity (ortholog) AND cytokine binding (ortholog) AND INVOLVED IN negative regulation of motor neuron apoptotic process (ortholog) AND negative regulation of neuron apoptotic process (ortholog) AND positive regulation of cell proliferation (ortholog) AND ASSOCIATED WITH Abnormalities Multiple (ortholog) AND FOUND IN CRLF-CLCF1 complex (ortholog) AND cytoplasm (ortholog) AND plasma membrane (ortholog) AND INTERACTS WITH C60 fullerene AND all-trans-retinoic acid AND tributylstannane | Chr16:19431472..19442747 | 10 |
| Sugp2 | gene:RGD | ENCODES a protein that exhibits RNA binding (inferred) AND INVOLVED IN RNA processing (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND 17alpha-ethynylestradiol (ortholog) | Chr16:19644374..19673741 | 10 |
| Slc25a42 | gene:RGD | ENCODES a protein that exhibits ADP transmembrane transporter activity (ortholog) AND AMP transmembrane transporter activity (ortholog) AND ATP transmembrane transporter activity (ortholog) AND INVOLVED IN ADP transport (ortholog) AND AMP transport (ortholog) AND ATP transport (ortholog) AND FOUND IN mitochondrial inner membrane (ortholog) AND mitochondrion (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND C60 fullerene AND pirinixic acid | Chr16:19697100..19720036 | 10 |
| Hapln4 | gene:RGD | ENCODES a protein that exhibits hyaluronic acid binding (inferred) AND INVOLVED IN cell adhesion (inferred) AND INTERACTS WITH C60 fullerene AND cadmium dichloride AND diuron | Chr16:19816321..19824506 | 10 |
| Gatad2a | gene:RGD | ENCODES a protein that exhibits protein binding bridging (ortholog) AND INVOLVED IN anterior neuropore closure (ortholog) AND blood vessel development (ortholog) AND embryonic body morphogenesis (ortholog) AND FOUND IN NuRD complex (ortholog) AND nucleus (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr16:19913558..20004379 | 10 |
| Atp13a1 | gene:RGD | ENCODES a protein that exhibits ATP binding (inferred) AND ATPase activity coupled to transmembrane movement of ions phosphorylative mechanism (inferred) AND metal ion binding (inferred) AND INVOLVED IN cation transport (inferred) AND FOUND IN integral to membrane (inferred) AND INTERACTS WITH 2 6-dinitrotoluene AND N-nitrosodiethylamine AND cadmium dichloride | Chr16:20100481..20116536 | 10 |
| Aadat | gene:RGD | ENCODES a protein that exhibits kynurenine-oxoglutarate transaminase activity AND pyridoxal phosphate binding AND 2-aminoadipate transaminase activity (ortholog) AND INVOLVED IN tryptophan catabolic process to kynurenine AND 2-oxoglutarate metabolic process (ortholog) AND glutamate metabolic process (ortholog) AND PARTICIPATES IN tryptophan metabolic pathway AND lysine biosynthetic pathway AND lysine degradation pathway AND FOUND IN mitochondrion AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND Aroclor 1254 | Chr16:32845006..32885600 | 10 |
| Aga | gene:RGD | ENCODES a protein that exhibits N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity AND protein self-association AND INVOLVED IN protein deglycosylation (ortholog) AND protein maturation (ortholog) AND ASSOCIATED WITH Lysosomal Storage Diseases (ortholog) AND FOUND IN lysosome AND endoplasmic reticulum (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND capsaicin AND benzo[a]pyrene (ortholog) | Chr16:41383536..41395394 | 10 |
| Asah1 | gene:RGD | ENCODES a protein that exhibits ceramidase activity (ortholog) AND INVOLVED IN lung development AND response to organic substance AND metabolic process (ortholog) AND PARTICIPATES IN ceramide signaling pathway AND sphingolipid metabolic pathway AND ASSOCIATED WITH Sphingolipidoses (ortholog) AND FOUND IN lysosome (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr16:54279253..54311084 | 10 |
| Mtmr7 | gene:RGD | ENCODES a protein that exhibits protein tyrosine phosphatase activity (inferred) AND INVOLVED IN inositol phosphate dephosphorylation (inferred) AND phosphatidylinositol dephosphorylation (inferred) AND PARTICIPATES IN fructose and mannose metabolic pathway AND FOUND IN cytosol (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ethanol | Chr16:54982204..55073152 | 10 |
| Tusc3 | gene:RGD | ENCODES a protein that exhibits dolichyl-diphosphooligosaccharide-protein glycotransferase activity (ortholog) AND magnesium ion transmembrane transporter activity (ortholog) AND INVOLVED IN cognition (ortholog) AND magnesium ion transport (ortholog) AND protein N-linked glycosylation via asparagine (ortholog) AND PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway AND N-linked glycan biosynthetic pathway AND ASSOCIATED WITH Prostatic Neoplasms (ortholog) AND FOUND IN mitochondrion (ortholog) AND oligosaccharyltransferase complex (ortholog) AND INTERACTS WITH 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene AND indole-3-methanol | Chr16:56760904..56929685 | 10 |
| Cldn23 | gene:RGD | ENCODES a protein that exhibits structural molecule activity (inferred) AND PARTICIPATES IN hepatitis C virus infection pathway AND FOUND IN integral to membrane (inferred) AND plasma membrane (inferred) AND tight junction (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND C60 fullerene AND 2 3 7 8-tetrachlorodibenzodioxine (ortholog) | Chr16:60109161..60110885 | 10 |
| Mfhas1 | gene:RGD | ASSOCIATED WITH Histiocytoma Benign Fibrous (ortholog) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND benzo[a]pyrene | Chr16:60251500..60330831 | 10 |
| malignant fibrous histiocytoma amplified sequence 1 | gene_ont:RGD_Ontology_RDO0005265 | ASSOCIATED WITH Histiocytoma Benign Fibrous (ortholog) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND benzo[a]pyrene | Chr16:60251500..60330831 | 10 |
| malignant fibrous histiocytoma amplified sequence 1 | gene_ont:RGD_Ontology_RDO0005309 | ASSOCIATED WITH Histiocytoma Benign Fibrous (ortholog) AND INTERACTS WITH C60 fullerene AND N-nitrosodiethylamine AND benzo[a]pyrene | Chr16:60251500..60330831 | 10 |
| Dctn6 | gene:RGD | ENCODES a protein that exhibits dynein binding (ortholog) AND PARTICIPATES IN vasopressin signaling pathway via receptor type 2 AND FOUND IN centrosome (ortholog) AND dynactin complex (ortholog) AND INTERACTS WITH 2 6-dinitrotoluene AND cadmium dichloride AND 17alpha-ethynylestradiol (ortholog) | Chr16:61805057..61824399 | 10 |
| Rbpms | gene:RGD | ENCODES a protein that exhibits poly(A) RNA binding (ortholog) AND transcription coactivator activity (ortholog) AND INVOLVED IN positive regulation of SMAD protein import into nucleus (ortholog) AND positive regulation of pathway-restricted SMAD protein phosphorylation (ortholog) AND INTERACTS WITH 17alpha-ethynylestradiol AND C60 fullerene AND all-trans-retinoic acid | Chr16:62009626..62163466 | 10 |
| Ppp2cb | gene:RGD | ENCODES a protein that exhibits phosphoprotein phosphatase activity AND protein C-terminus binding AND protein serine/threonine phosphatase activity AND INVOLVED IN negative regulation of Ras protein signal transduction AND protein dephosphorylation AND negative regulation of apoptotic process (ortholog) AND PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway AND Trypanosoma cruzi infection pathway AND Wnt signaling pathway AND FOUND IN cytoplasm (ortholog) AND protein phosphatase type 2A complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND ammonium chloride | Chr16:62330513..62351968 | 10 |
| Nrg1 | gene:RGD | ENCODES a protein that exhibits ErbB-3 class receptor binding AND ErbB-2 class receptor binding (ortholog) AND growth factor activity (ortholog) AND INVOLVED IN glucose transport AND myelination AND regulation of blood pressure AND PARTICIPATES IN angiotensin II signaling pathway AND epidermal growth factor/neuregulin signaling pathway AND glypican signaling pathway AND FOUND IN apical plasma membrane (ortholog) AND cytoplasm (ortholog) AND extracellular space (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 4 6-trinitrotoluene | Chr16:63937796..64126183 | 10 |
| Eif4ebp1 | gene:RGD | ENCODES a protein that exhibits eukaryotic initiation factor 4E binding AND translation initiation factor binding AND INVOLVED IN lung development AND negative regulation of protein complex assembly AND negative regulation of translational initiation AND PARTICIPATES IN insulin signaling pathway AND mTOR signaling pathwayRNA transport pathway AND ASSOCIATED WITH Ataxia Telangiectasia (ortholog) AND Tuberous Sclerosis (ortholog) AND FOUND IN cytoplasm AND nucleus AND protein complex AND INTERACTS WITH 2 4 6-trinitrotoluene AND 2-nitrofluorene AND 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | Chr16:69110522..69123895 | 10 |
| Brf2 | gene:RGD | ENCODES a protein that exhibits zinc ion binding (inferred) AND INVOLVED IN DNA-dependent transcription initiation (inferred) AND regulation of transcription DNA-dependent (inferred) AND FOUND IN nucleus (inferred) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND diuron | Chr16:69250416..69255138 | 10 |
| Zfp703 | gene:RGD | ENCODES a protein that exhibits repressing transcription factor binding (ortholog) AND INVOLVED IN adherens junction assembly (ortholog) AND mammary gland epithelial cell differentiation (ortholog) AND negative regulation of homotypic cell-cell adhesion (ortholog) AND FOUND IN cytoplasm (ortholog) AND nucleus (ortholog) AND INTERACTS WITH C60 fullerene AND all-trans-retinoic acid AND 17beta-estradiol (ortholog) | Chr16:69405004..69409137 | 10 |
| Hook3 | gene:RGD | ENCODES a protein that exhibits identical protein binding (ortholog) AND microtubule binding (ortholog) AND INVOLVED IN Golgi localization (ortholog) AND cytoplasmic microtubule organization (ortholog) AND early endosome to late endosome transport (ortholog) AND FOUND IN FHF complex (ortholog) AND Golgi apparatus (ortholog) AND HOPS complex (ortholog) AND INTERACTS WITH 17beta-estradiol AND 2 3 7 8-tetrachlorodibenzodioxine AND 2 6-dinitrotoluene | Chr16:70338144..70424173 | 10 |
| Fnta | gene:RGD | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity AND drug binding AND isoprenoid binding AND INVOLVED IN negative regulation of apoptotic process AND negative regulation of nitric-oxide synthase biosynthetic process AND positive regulation of cell cycle AND FOUND IN CAAX-protein geranylgeranyltransferase complex AND cytoplasm AND microtubule associated complex (ortholog) AND INTERACTS WITH (-)-perillyl alcohol AND 2 4-dinitrotoluene AND 2 6-dinitrotoluene | Chr16:70440340..70458433 | 10 |
| Ash2l | gene:RGD | ENCODES a protein that exhibits histone methyltransferase activity (H3-K4 specific) (ortholog) AND transcription regulatory region DNA binding (ortholog) AND INVOLVED IN histone H3-K4 methylation (ortholog) AND positive regulation of cell proliferation (ortholog) AND positive regulation of transcription from RNA polymerase II promoter (ortholog) AND FOUND IN MLL1 complex (ortholog) AND Set1C/COMPASS complex (ortholog) AND histone methyltransferase complex (ortholog) AND INTERACTS WITH 2 4-dinitrotoluene AND 2 6-dinitrotoluene AND cadmium dichloride | Chr16:70617717..70639166 | 10 |
| Htra4 | gene:RGD | ENCODES a protein that exhibits insulin-like growth factor binding (inferred) AND serine-type endopeptidase activity (inferred) AND INVOLVED IN proteolysis (inferred) AND regulation of cell growth (inferred) AND FOUND IN extracellular region (inferred) AND INTERACTS WITH 17alpha-ethynylestradiol AND 2 6-dinitrotoluene | Chr16:71424709..71438884 | 10 |